Simon J. Davis - Publications, H-index & Citations

Simon J. Davis

university of oxford

61H指数

283论文数

1.5W被引数

收录论文 117

发表时间

Realizing the potential of agonistic antibody immunotherapy 实现激动性抗体免疫治疗的潜力

Nature Reviews Drug Discovery

IF101.8

2026-05-19

PREAI

Mark S. Cragg; Xiaojie Yu; Christopher Paluch; Simon J. Davis

PD-1 signaling and PD-1 blockade–mediated tumor control are established at microvillar T cell contacts PD-1信号传导和PD-1阻断介导的肿瘤控制在小微绒毛T细胞接触处建立

Science Immunology

IF16.3

2026-05-15

PREAI

Edward Jenkins; Martin Fellermeyer; Daniel F. Heraghty; Sumana Sharma; Tanmay Mitra; Mateusz Kotowski; Joseph Clarke; Yuan Lui; Sam Daly; Zach Marin; Debasis Banik; Markus Körbel; Emily Zhi Qing Ng; Thomas Lister; Ana Mafalda Santos; Steven F. Lee; Michael L. Dustin; Simon J. Davis; David Klenerman

Spatial protein expression patterns across pathologically-associated fibers revealed molecular specialization in inclusion body myositis 病理相关纤维上的空间蛋白质表达模式揭示了包涵体肌炎中的分子特化现象。

Cell Communication and Signaling

IF8.9

2026-02-21

OAAI

T. I. Nijssen; S. Davis; R. A. O’Shaughnessy; E. Bos; A. J. van der Kooi; J. Raaphorst; E. Aronica; R. Fischer; B. M. Kessler; Vered Raz

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti-CEACAM5 CAR T-Cell Efficacy Against Colorectal Cancer 肿瘤微环境的酶重塑增强了Anti-CEACAM5 car-t细胞对结直肠癌的疗效

Advanced Science

IF14.1

2026-01-22

OAAI

Debasis Banik; Christopher J. Ward; Soura Chakraborty; Ziwei Zhang; Daniel Heraghty; Prasanna Suresh; Bing Li; Shekhar Kedia; Jhuma Pramanik; Simon J. Davis; James P. Roy; Michael A. Chapman; Bidesh Mahata; David Klenerman

From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes

MBIO

IF4.7

2025-02-05

OAAI

Reis, Ana Luisa; Rathakrishnan, Anusyah; Petrovan, Vlad; Islam, Muneeb; Goatley, Lynnette; Moffat, Katy; Vuong, Mai Tuyet; Lui, Yuan; Davis, Simon J.; Ikemizu, Shinji; Dixon, Linda K.

POLCAM: instant molecular orientation microscopy for the life sciences POLCAM: 生命科学的即时分子取向显微镜

NATURE METHODS

IF32.1

2024-10-07

OAAI

Bruggeman, Ezra; Zhang, Oumeng; Needham, Lisa-Maria; Korbel, Markus; Daly, Sam; Cheetham, Matthew; Peters, Ruby; Wu, Tingting; Klymchenko, Andrey S.; Davis, Simon J.; Paluch, Ewa K.; Klenerman, David; Lew, Matthew D.; O'Holleran, Kevin; Lee, Steven F.

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis

SCIENTIFIC REPORTS

IF3.9

2024-08-28

OAAI

Quinn, Joel; Salman, Ahmed; Paluch, Christopher; Jackson-Wood, Matthew; McClements, Michelle E.; Luo, Jian; Davis, Simon J.; Cornall, Richard J.; MacLaren, Robert E.; Dendrou, Calliope A.; Xue, Kanmin

The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling

CELL COMMUNICATION AND SIGNALING

IF8.9

2024-05-24

OAAI

Santos, Rita F.; Linhares, Annika de Sousa; Steinberger, Peter; Davis, Simon. J.; Oliveira, Liliana; Carmo, Alexandre M.

High-density volumetric super-resolution microscopy

NATURE COMMUNICATIONS

IF15.7

2024-03-02

OAAI

Daly, Sam; Fernandes, Joao Ferreira; Bruggeman, Ezra; Handa, Anoushka; Peters, Ruby; Benaissa, Sarah; Zhang, Boya; Beckwith, Joseph S.; Sanders, Edward W.; Sims, Ruth R.; Klenerman, David; Davis, Simon J.; O'Holleran, Kevin; Lee, Steven F.

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases

IMMUNITY

IF26.3

2024-02-01

OAAI

Lippert, Anna H.; Paluch, Christopher; Gaglioni, Meike; Vuong, Mai T.; Mccoll, James; Jenkins, Edward; Fellermeyer, Martin; Clarke, Joseph; Sharma, Sumana; da Silva, Sara Moreira; Akkaya, Billur; Anzilotti, Consuelo; Morgan, Sara H.; Jessup, Claire F.; Korbel, Markus; Gileadi, Uzi; Leitner, Judith; Knox, Rachel; Chirifu, Mami; Huo, Jiandong; Yu, Susan; Ashman, Nicole; Lui, Yuan; Wilkinson, Ian; Attfield, Kathrine E.; Fugger, Lars; Robertson, Nathan J.; Lynch, Christopher J.; Murray, Lynne; Steinberger, Peter; Santos, Ana Mafalda; Lee, Steven F.; Cornall, Richard J.; Klenerman, David; Davis, Simon J.

A high-throughput two-cell assay for interrogating inhibitory signaling pathways in T cells

LIFE SCIENCE ALLIANCE

IF2.9

2023-12-07

OAAI

Sharma, Sumana; Whitehead, Toby; Kotowski, Mateusz; Ng, Emily Zhi Qing; Clarke, Joseph; Leitner, Judith; Chen, Yi-Ling; Santos, Ana Mafalda; Steinberger, Peter; Davis, Simon J.

A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein

EMERGING MICROBES & INFECTIONS

IF7.5

2023-10-19

OAAI

Rathakrishnan, Anusyah; Reis, Ana L.; Petrovan, Vlad; Goatley, Lynnette C.; Moffat, Katy; Lui, Yuan; Vuong, Mai T.; Ikemizu, Shinji; Davis, Simon J.; Dixon, Linda K.

Combination CD200R/PD-1 blockade in a humanised mouse model

IMMUNOTHERAPY ADVANCES

IF4.9

2023-03-30

OAAI

Fellermeyer, Martin; Anzilotti, Consuelo; Paluch, Christopher; Cornall, Richard J.; Davis, Simon J.; Gileadi, Uzi

Antigen discrimination by T cells relies on size-constrained microvillar contact

NATURE COMMUNICATIONS

IF15.7

2023-03-23

OAAI

Jenkins, Edward; Korbel, Markus; O'Brien-Ball, Caitlin; McColl, James; Chen, Kevin Y.; Kotowski, Mateusz; Humphrey, Jane; Lippert, Anna H.; Brouwer, Heather; Santos, Ana Mafalda; Lee, Steven F.; Davis, Simon J.; Klenerman, David

The kinase occupancy of T cell coreceptors reconsidered 重新考虑T细胞共受体的激酶占用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-01

OAAI

Morch, Alexander M.; Schneider, Falk; Jenkins, Edward; Santos, Ana Mafalda; Fraser, Scott E.; Davis, Simon J.; Dustin, Michael L.

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

NATURE IMMUNOLOGY

IF27.6

2022-08-23

103

OAAI

Kennedy, Alan; Waters, Erin; Rowshanravan, Behzad; Hinze, Claudia; Williams, Cayman; Janman, Daniel; Fox, Thomas A.; Booth, Claire; Pesenacker, Anne M.; Halliday, Neil; Soskic, Blagoje; Kaur, Satdip; Qureshi, Omar S.; Morris, Emma C.; Ikemizu, Shinji; Paluch, Christopher; Huo, Jiandong; Davis, Simon J.; Boucrot, Emmanuel; Walker, Lucy S. K.; Sansom, David M.

Single-cell measurements of two-dimensional binding affinity across cell contacts

BIOPHYSICAL JOURNAL

IF3.1

2021-11-01

OAAI

Chouliara, Manto; Junghans, Victoria; Dam, Tommy; Santos, Ana Mafalda; Davis, Simon J.; Jonsson, Peter

Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling 在密切接触时捕获或减缓T细胞受体的扩散启动T细胞信号传导

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-09-15

OAAI

Chen, Kevin Y.; Jenkins, Edward; Korbel, Markus; Ponjavic, Aleks; Lippert, Anna H.; Santos, Ana Mafalda; Ashman, Nicole; O'Brien-Ball, Caitlin; McBride, Jemma; Klenerman, David; Davis, Simon J.

PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition

NATURE COMMUNICATIONS

IF15.7

2021-05-12

OAAI

Li, Kaitao; Yuan, Zhou; Lyu, Jintian; Ahn, Eunseon; Davis, Simon J.; Ahmed, Rafi; Zhu, Cheng

HLA-E-restricted, Gag-specific CD8+ T cells can suppress HIV-1 infection, offering vaccine opportunities

SCIENCE IMMUNOLOGY

IF16.3

2021-03-04

OAAI

Yang, Hongbing; Rei, Margarida; Brackenridge, Simon; Brenna, Elena; Sun, Hong; Abdulhaqq, Shaheed; Liu, Michael K. P.; Ma, Weiwei; Kurupati, Prathiba; Xu, Xiaoning; Cerundolo, Vincenzo; Jenkins, Edward; Davis, Simon J.; Sacha, Jonah B.; Frueh, Klaus; Picker, Louis J.; Borrow, Persephone; Gillespie, Geraldine M.; McMichael, Andrew J.

研究方向