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H

Hagen Tilgner

Weill Cornell Medicine
H指数:30
被引数:1.9万

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Spatial isoform sequencing at single-cell resolution reveals cell-type-specific spatial isoform variability in multiple brain cell types

单细胞分辨率下的空间异构体测序揭示多种脑细胞类型中细胞类型特异性的空间异构体变异性

Nature Methods
IF32.1
2026-09-040
OAAI
Lieke Michielsen; Andrey D. Prjibelski; Careen Foord; Yelizaveta Spiegelman; Taewoo Kim; Wen Hu; Julien Jarroux; Justine Hsu; Rebecca Pfeil; Xinyi Zhang; Li Gan; Alexandru I. Tomescu; Iman Hajirasouliha; Hagen U. Tilgner
A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain

一项单细胞、长读长、异构体解析的FTD病例对照研究揭示了人类大脑中细胞类型特异性和广泛的剪接失调。

Cell Reports
IF6.9
2025-09-050
OAAI
Natan Belchikov; Wen Hu; Li Fan; Anoushka Joglekar; Yi He; Careen Foord; Julien Jarroux; Justine Hsu; Shaun Pollard; Sadaf Amin; Andrey D. Prjibelski; Shiaoching Gong; Sai Zhang; Roberta Giannelli; Harro Seelaar; Alexandru I. Tomescu; M. Elizabeth Ross; Alissa Nana Li; Lea T. Grinberg; Salvatore Spina; Bruce L. Miller; Johnathan Cooper-Knock; Michael P. Snyder; William W. Seeley; Priyanka Rao-Ruiz; Sabine Spijker; August B. Smit; Claire D. Clelland; Li Gan; Hagen U. Tilgner
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types
Nature Communications
IF15.7
2025-08-290
OAAI
Careen Foord; Andrey D. Prjibelski; Wen Hu; Lieke Michielsen; Andrea Vandelli; Oleksandr Narykov; Brian Evans; Justine Hsu; Natan Belchikov; Julien Jarroux; Yi He; M. Elizabeth Ross; Iman Hajirasouliha; Gian Gaetano Tartaglia; Dmitry Korkin; Alexandru I. Tomescu; Hagen U. Tilgner
Combined single-cell profiling of chromatin–transcriptome and splicing across brain cell types, regions and disease state

Hu, W.; Foord, C.; Hsu, J.; Fan, L.; Corley, M.J.; Lanjewar, S.N.; Xu, S.; Belchikov, N.; He, Y.; Pang, A.P.S.; et al. 脑细胞类型、区域和疾病状态下组蛋白-转录组及剪接的联合单细胞分析。Nat. Biotechnol. 2025, 1–13. [Google Scholar] [CrossRef] [PubMed]

Nature Biotechnology
IF41.7
2025-07-220
OAAI
Wen Hu; Careen Foord; Justine Hsu; Li Fan; Michael J. Corley; Samantha N. Lanjewar; Siwei Xu; Natan Belchikov; Yi He; Alina P. S. Pang; Tarun N. Bhatia; Julien Jarroux; Anoushka Joglekar; Teresa A. Milner; Lishomwa C. Ndhlovu; Jing Zhang; Eduardo Butelman; Steven A. Sloan; Virginia M. Y. Lee; Li Gan; Hagen U. Tilgner
The single-cell opioid responses in the context of HIV (SCORCH) consortium
MOLECULAR PSYCHIATRY
IF10.1
2024-06-151
OAAI
Ament, Seth A.; Campbell, Rianne R.; Lobo, Mary Kay; Receveur, Joseph P.; Agrawal, Kriti; Borjabad, Alejandra; Byrareddy, Siddappa N.; Chang, Linda; Clarke, Declan; Emani, Prashant; Gabuzda, Dana; Gaulton, Kyle J.; Giglio, Michelle; Giorgi, Federico M.; Gok, Busra; Guda, Chittibabu; Hadas, Eran; Herb, Brian R.; Hu, Wen; Huttner, Anita; Ishmam, Mohammad R.; Jacobs, Michelle M.; Kelschenbach, Jennifer; Kim, Dong-Wook; Lee, Cheyu; Liu, Shuhui; Liu, Xiaokun; Madras, Bertha K.; Mahurkar, Anup A.; Mash, Deborah C.; Mukamel, Eran A.; Niu, Meng; O'Connor, Richard M.; Pagan, Chelsea M.; Pang, Alina P. S.; Pillai, Piya; Repunte-Canonigo, Vez; Ruzicka, W. Brad; Stanley, Jay; Tickle, Timothy; Tsai, Shang-Yi A.; Wang, Allen; Wills, Lauren; Wilson, Alyssa M.; Wright, Susan N.; Xu, Siwei; Yang, Junchen; Zand, Maryam; Zhang, Le; Zhang, Jing; Akbarian, Schahram; Buch, Shilpa; Cheng, Christine S.; Corley, Michael J.; Fox, Howard S.; Gerstein, Mark; Gummuluru, Suryaram; Heiman, Myriam; Ho, Ya-Chi; Kellis, Manolis; Kenny, Paul J.; Kluger, Yuval; Milner, Teresa A.; Moore, David J.; Morgello, Susan; Ndhlovu, Lishomwa C.; Rana, Tariq M.; Sanna, Pietro Paolo; Satterlee, John S.; Sestan, Nenad; Spector, Stephen A.; Spudich, Serena; Tilgner, Hagen U.; Volsky, David J.; White, Owen R.; Williams, Dionne W.; Zeng, Hongkui
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification

用于转录本鉴定和定量的长读rna-seq方法的系统评估

NATURE METHODS
IF32.1
2024-06-0715
OAAI
Pardo-Palacios, Francisco J.; Wang, Dingjie; Reese, Fairlie; Diekhans, Mark; Carbonell-Sala, Silvia; Williams, Brian; Loveland, Jane E.; De Maria, Maite; Adams, Matthew S.; Balderrama-Gutierrez, Gabriela; Behera, Amit K.; Gonzalez Martinez, Jose M.; Hunt, Toby; Lagarde, Julien; Liang, Cindy E.; Li, Haoran; Meade, Marcus Jerryd; Moraga Amador, David A.; Prjibelski, Andrey D.; Birol, Inanc; Bostan, Hamed; Brooks, Ashley M.; Celik, Muhammed Hasan; Chen, Ying; Du, Mei R. M.; Felton, Colette; Goeke, Jonathan; Hafezqorani, Saber; Herwig, Ralf; Kawaji, Hideya; Lee, Joseph; Li, Jian-Liang; Lienhard, Matthias; Mikheenko, Alla; Mulligan, Dennis; Nip, Ka Ming; Pertea, Mihaela; Ritchie, Matthew E.; Sim, Andre D.; Tang, Alison D.; Wan, Yuk Kei; Wang, Changqing; Wong, Brandon Y.; Yang, Chen; Barnes, If; Berry, Andrew E.; Capella-Gutierrez, Salvador; Cousineau, Alyssa; Dhillon, Namrita; Fernandez-Gonzalez, Jose M.; Ferrandez-Peral, Luis; Garcia-Reyero, Natalia; Goetz, Stefan; Hernandez-Ferrer, Carles; Kondratova, Liudmyla; Liu, Tianyuan; Martinez-Martin, Alessandra; Menor, Carlos; Mestre-Tomas, Jorge; Mudge, Jonathan M.; Panayotova, Nedka G.; Paniagua, Alejandro; Repchevsky, Dmitry; Ren, Xingjie; Rouchka, Eric; Saint-John, Brandon; Sapena, Enrique; Sheynkman, Leon; Smith, Melissa Laird; Suner, Marie-Marthe; Takahashi, Hazuki; Youngworth, Ingrid A.; Carninci, Piero; Denslow, Nancy D.; Guigo, Roderic; Hunter, Margaret E.; Maehr, Rene; Shen, Yin; Tilgner, Hagen U.; Wold, Barbara J.; Vollmers, Christopher; Frankish, Adam; Au, Kin Fai; Sheynkman, Gloria M.; Mortazavi, Ali; Conesa, Ana; Brooks, Angela N.
Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain

基于单细胞长读测序的映射揭示了发育中和成年小鼠和人脑中的特殊剪接模式

Nature Neuroscience
IF20
2024-04-090
OAAI
Anoushka Joglekar; Wen Hu; Bei Zhang; Oleksandr Narykov; Mark Diekhans; Jordan Marrocco; Jennifer Balacco; Lishomwa C. Ndhlovu; Teresa A. Milner; Olivier Fedrigo; Erich D. Jarvis; Gloria Sheynkman; Dmitry Korkin; M. Elizabeth Ross; Hagen U. Tilgner
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue

单核同工型RNA测序可解锁冷冻脑组织中的条形码外显子连接

NATURE BIOTECHNOLOGY
IF41.7
2022-03-0758
OAAI
Hardwick, Simon A.; Hu, Wen; Joglekar, Anoushka; Fan, Li; Collier, Paul G.; Foord, Careen; Balacco, Jennifer; Lanjewar, Samantha; Sampson, Maureen McGuirk; Koopmans, Frank; Prjibelski, Andrey D.; Mikheenko, Alla; Belchikov, Natan; Jarroux, Julien; Lucas, Anne Bergstrom; Palkovits, Miklos; Luo, Wenjie; Milner, Teresa A.; Ndhlovu, Lishomwa C.; Smit, August B.; Trojanowski, John Q.; Lee, Virginia M. Y.; Fedrigo, Olivier; Sloan, Steven A.; Tombacz, Dora; Ross, M. Elizabeth; Jarvis, Erich; Boldogkoi, Zsolt; Gan, Li; Tilgner, Hagen U.
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

出生后小鼠大脑的空间分辨的大脑区域和细胞类型特异性同工型图谱

NATURE COMMUNICATIONS
IF15.7
2021-01-19115
OAAI
Joglekar, Anoushka; Prjibelski, Andrey; Mahfouz, Ahmed; Collier, Paul; Lin, Susan; Schlusche, Anna Katharina; Marrocco, Jordan; Williams, Stephen R.; Haase, Bettina; Hayes, Ashley; Chew, Jennifer G.; Weisenfeld, Neil I.; Wong, Man Ying; Stein, Alexander N.; Hardwick, Simon A.; Hunt, Toby; Wang, Qi; Dieterich, Christoph; Bent, Zachary; Fedrigo, Olivier; Sloan, Steven A.; Risso, Davide; Jarvis, Erich D.; Flicek, Paul; Luo, Wenjie; Pitt, Geoffrey S.; Frankish, Adam; Smit, August B.; Ross, M. Elizabeth; Tilgner, Hagen U.
SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

SynGO: 一个基于证据的、专家策划的突触知识库

NEURON
IF15
2019-07-01444
OAAI
Koopmans, Frank; van Nierop, Pim; Andres-Alonso, Maria; Bymes, Andrea; Cijsouw, Tony; Coba, Marcelo P.; Cornelisse, L. Niels; Farrell, Ryan J.; Goldschmidt, Hana L.; Howrigan, Daniel P.; Hussain, Natasha K.; Imig, Cordelia; de Jong, Arthur P. H.; Jung, Hwajin; Kohansalnodehi, Mandokht; Kramarz, Barbara; Lipstein, Noa; Lovering, Ruth C.; MacGillavry, Harold; Mariano, Vittoria; Mi, Huaiyu; Ninov, Momchil; Osumi-Sutherland, David; Pielot, Rainer; Smalla, Karl-Heinz; Tang, Haiming; Tashman, Katherine; Toonen, Ruud F. G.; Verpelli, Chiara; Reig-Viader, Rita; Watanabe, Kyoko; van Weering, Jan; Achsel, Tilmann; Ashrafi, Ghazaleh; Asi, Nimra; Brown, Tyler C.; De Camilli, Pietro; Feuermann, Marc; Foulger, Rebecca E.; Gaudet, Pascale; Joglekar, Anoushka; Kanellopoulos, Alexandros; Malenka, Robert; Nicoll, Roger A.; Pulido, Camila; de Juan-Sanz, Jaime; Sheng, Morgan; Sudhof, Thomas C.; Tilgner, Hagen U.; Bagni, Claudia; Bayes, Alex; Biederer, Thomas; Brose, Nils; Chua, John Jia En; Dieterich, Daniela C.; Gundelfinger, Eckart D.; Hoogenraad, Casper; Huganir, Richard L.; Jahn, Reinhard; Kaeser, Pascal S.; Kim, Eunjoon; Kreutz, Michael R.; McPherson, Peter S.; Neale, Ben M.; O'Connor, Vincent; Posthuma, Danielle; Ryan, Timothy A.; Sala, Carlo; Feng, Guoping; Hyman, Steven E.; Thomas, Paul D.; Smit, August B.; Verhage, Matthijs

研究方向

暂未获取到该数据
A
Anoushka Joglekar
H 指数:14论文数:35被引数:2,387
M
M Snyder
H 指数:210论文数:3,272被引数:20.0万
胡
胡雯
H 指数:17论文数:55被引数:1,119
R
Roderic Guigó
H 指数:126论文数:707被引数:12.6万
J
Julien Jarroux
H 指数:9论文数:31被引数:1,431
A
Andrey D. Prjibelski
H 指数:22论文数:66被引数:3.5万
C
Careen Foord
H 指数:7论文数:19被引数:290
M
M. Elizabeth Ross
H 指数:49论文数:175被引数:9,921
A
August B. Smit
H 指数:83论文数:531被引数:3.1万
N
Natan Belchikov
H 指数:5论文数:17被引数:222