Po‐Ssu Huang - Publications, H-index & Citations

Po‐Ssu Huang

stanford university

38H指数

112论文数

1.1W被引数

收录论文 39

发表时间

De novo design of RNA pseudoknots with deep learning 基于深度学习的RNA假结从头设计

Science

IF45.8

2026-08-27

PREAI

Jill Townley; Wipapat Kladwang; David Baker; Hamish M. Blair; Christian A. Choe; Gina El Nesr; Andrew Favor; Eli Fisker; Daniel B. Haack; Shujun He; Jason Hingey; Po-Ssu Huang; Rui Huang; Chaitanya K. Joshi

ADAPT-M: a workflow for rapid, quantitative in vitro measurements of enriched protein libraries ADAPT-M：一种用于快速、定量体外测量富集蛋白质文库的工作流程

Nature Communications

IF15.7

2026-07-15

OAAI

Carla P. Perez; Nicole V. DelRosso; Cameron L. Noland; Udit Parekh; Christian A. Choe; Raphael R. Eguchi; Qi Wen; Polly M. Fordyce; Po-Ssu Huang

Structural ontogeny of protein-protein interactions 蛋白质相互作用的结构个体发育学

Science

IF45.8

2026-02-12

PREAI

Aerin Yang; Hanlun Jiang; Kevin M. Jude; Deniz Akpinaroglu; Stephan Allenspach; Alex Jie Li; James Bowden; Carla Patricia Perez; Liu Liu; Po-Ssu Huang; Tanja Kortemme; Jennifer Listgarten; K. Christopher Garcia

High throughput mutational characterization of the GPCR ligand C5a using yeast display and deep sequencing 利用酵母展示和深度测序技术对GPCR配体C5a进行高通量突变表征

Structure

IF4.3

2025-10-27

PREAI

Yu Xu; Kaushik Thakkar; Li Guan; Yu Miao; Manal Mehibel; Robert B. Lee; David Marciano; Vignesh Viswanathan; Ziwei Wang; Jinglong Wang; Lu Ji; Hongbin Cao; Camille Fisher Petrakian; Jocelyn Valenzuela; Edward LaGory; Xianglian Jia; Eui Jung Moon; Rodolph Martinez; Fang Wu; Richard L. Frock; Everett J. Moding; Quynh-Thu Le; Erinn B. Rankin; Cheng Zhang; Possu Huang; Monica M. Olcina; Amato J. Giaccia; Edward E. Graves

Assessing generative model coverage of protein structures with SHAPES 评估蛋白质结构的生成模型覆盖率与SHAPES

Cell Systems

IF7.7

2025-07-29

OAAI

Tianyu Lu; Melissa Liu; Yilin Chen; Jinho Kim; Po-Ssu Huang

Targeting peptide antigens using a multiallelic MHC I-binding system

NATURE BIOTECHNOLOGY

IF41.7

2024-12-13

OAAI

Du, Haotian; Mallik, Leena; Hwang, Daniel; Sun, Yi; Kaku, Chengzi; Hoces, Daniel; Sun, Shirley M.; Ghinnagow, Reem; Carro, Stephen D.; Phan, Hoang Anh T.; Gupta, Sagar; Blackson, Wyatt; Lee, Hyejin; Choe, Christian A.; Dersh, Devin; Liu, Jingjia; Bell, Braxton; Yang, Hongli; Papadaki, Georgia F.; Young, Michael C.; Zhou, Emily; El Nesr, Gina; Goli, Kimia Dasteh; Eisenlohr, Laurence C.; Minn, Andy J.; Hernandez-Lopez, Rogelio A.; Jardine, Joseph G.; Sgourakis, Nikolaos G.; Huang, Po-Ssu

A general system for targeting MHC class II-antigen complex via a single adaptable loop

NATURE BIOTECHNOLOGY

IF41.7

2024-12-13

PREAI

Du, Haotian; Liu, Jingjia; Jude, Kevin M.; Yang, Xinbo; Li, Ying; Bell, Braxton; Yang, Hongli; Kassardjian, Audrey; Blackson, Wyatt; Mobedi, Ali; Parekh, Udit; Sperberg, R. Andres Parra; Julien, Jean-Philippe; Mellins, Elizabeth D.; Garcia, K. Christopher; Huang, Po-Ssu

An all-atom protein generative model

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-06-25

OAAI

Chu, Alexander E.; Kim, Jinho; Cheng, Lucy; El Nesr, Gina; Xu, Minkai; Shuai, Richard W.; Huang, Po-Ssu

Sparks of function by de novo protein design 从头蛋白质设计的功能火花

NATURE BIOTECHNOLOGY

IF41.7

2024-02-15

PREAI

Chu, Alexander E.; Lu, Tianyu; Huang, Po-Ssu

A cysteine-specific solubilizing tag strategy enables efficient chemical protein synthesis of difficult targets

CHEMICAL SCIENCE

IF7.4

2024-01-01

OAAI

Li, Wenchao; Jacobsen, Michael T.; Park, Claire; Jung, Jae Un; Lin, Nai-Pin; Huang, Po-Ssu; Lal, Rayhan A.; Chou, Danny Hung-Chieh

How can the protein design community best support biologists who want to harness AI tools for protein structure prediction and design?

CELL SYSTEMS

IF7.7

2023-08-01

PREAI

Hoecker, Birte; Lu, Peilong; Glasgow, Anum; Marks, Debora S.; Chatterjee, Pranam; Slusky, Joanna S. G.; Schueler-Furman, Ora; Huang, Possu

Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins 全合成平台可快速生成基于四价双特异性纳米抗体的免疫球蛋白

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-06-05

OAAI

Mindrebo, Laetitia Misson; Liu, Hejun; Ozorowski, Gabriel; Tran, Quoc; Woehl, Jordan; Khalek, Irene; Smith, Jessica M.; Barman, Shawn; Zhao, Fangzhu; Keating, Celina; Limbo, Oliver; Verma, Megan; Liu, Jingjia; Stanfield, Robyn L.; Zhu, Xueyong; Turner, Hannah L.; Sok, Devin; Huang, Po-Ssu; Burton, Dennis R.; Ward, Andrew B.; Wilson, Ian A.; Jardine, Joseph G.

Ig-VAE: Generative modeling of protein structure by direct 3D coordinate generation Ig-vae: 通过直接3D坐标生成的蛋白质结构生成建模

plos biology

IF3.6

2022-06-27

OAAI

Eguchi, Raphael R.; Choe, Christian A.; Huang, Po-Ssu

Interleukin-2 superkines by computational design 通过计算设计Interleukin-2超级因子

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-16

OAAI

Ren, Junming; Chu, Alexander E.; Jude, Kevin M.; Picton, Lora K.; Kare, Aris J.; Su, Leon; Romero, Alejandra Montano; Huang, Po-Ssu; Garcia, K. Christopher

Chimeric mutants of staphylococcal hemolysin, which act as both one-component and two-component hemolysin, created by grafting the stem domain

FEBS JOURNAL

IF4.2

2022-02-16

PREAI

Ghanem, Nouran; Kanagami, Natsuki; Matsui, Takashi; Takeda, Kein; Kaneko, Jun; Shiraishi, Yasuyuki; Choe, Christian A.; Uchikubo-Kamo, Tomomi; Shirouzu, Mikako; Hashimoto, Tsubasa; Ogawa, Tomohisa; Matsuura, Tomoaki; Huang, Po-Ssu; Yokoyama, Takeshi; Tanaka, Yoshikazu

Protein sequence design with a learned potential

NATURE COMMUNICATIONS

IF15.7

2022-02-08

OAAI

Anand, Namrata; Eguchi, Raphael; Mathews, Irimpan I.; Perez, Carla P.; Derry, Alexander; Altman, Russ B.; Huang, Po-Ssu

Structure-based protein design with deep learning 基于结构的蛋白质设计与深度学习

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2021-12-01

OAAI

Ovchinnikov, Sergey; Huang, Po-Ssu

Theoretical basis for stabilizing messenger RNA through secondary structure design (vol 49, pg 10604, 2021)

NUCLEIC ACIDS RESEARCH

IF13.1

2021-09-30

OAAI

Wayment-Steele, Hannah K.; Kim, Do Soon; Choe, Christian A.; Nicol, John J.; Wellington-Oguri, Roger; Watkins, Andrew M.; Sperberg, R. Andres Parra; Huang, Po-Ssu; Participants, Eterna; Das, Rhiju

Theoretical basis for stabilizing messenger RNA through secondary structure design

NUCLEIC ACIDS RESEARCH

IF13.1

2021-09-14

OAAI

Wayment-Steele, Hannah K.; Kim, Do Soon; Choe, Christian A.; Nicol, John J.; Wellington-Oguri, Roger; Watkins, Andrew M.; Sperberg, R. Andres Parra; Huang, Po-Ssu; Participants, Eterna; Das, Rhiju

Optical control of fast and processive engineered myosins in vitro and in living cells 体外和活细胞中快速和加工的工程化肌球蛋白的光学控制

NATURE CHEMICAL BIOLOGY

IF13.7

2021-02-18

PREAI

Ruijgrok, Paul V.; Ghosh, Rajarshi P.; Zemsky, Sasha; Nakamura, Muneaki; Gong, Rui; Ning, Lin; Chen, Robert; Vachharajani, Vipul T.; Chu, Alexander E.; Anand, Namrata; Eguchi, Raphael R.; Huang, Po-Ssu; Lin, Michael Z.; Alushin, Gregory M.; Liphardt, Jan T.; Bryant, Zev

研究方向