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CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies Richard, Jonathan; Sannier, Geremy; Zhu, Li; Prevost, Jeremie; Marchitto, Lorie; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Kim, Hongil; Sun, Yaping; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Delgado, Gloria-Gabrielle; Dube, Mathieu; Kirchhoff, Frank; Hahn, Beatrice H.; Kumar, Priti; Kaufmann, Daniel E.; Finzi, Andres 分享 收藏
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Systemic Treatment with siRNA Targeting Gamma-Secretase Activating Protein Inhibits Amyloid- β Accumulation in Alzheimer's Disease Kim, Sunghwa; Ullah, Irfan; Beloor, Jagadish; Chung, Kunho; Kim, Jongkil; Yi, Yujong; Kang, Eunhwa; Yun, Gyeongju; Heo, Seoyoun; Pyun, Seon-Hong; Kim, Seung Hyun; Kumar, Priti; Lee, Sang-Kyung 分享 收藏
Proof- of- concept studies with a computationally designed Mpro inhibitor as a synergistic combination regimen alternative to Paxlovid Papini, Christina; Ullah, Irfan; Ranjan, Amalendu P.; Zhang, Shuo; Wu, Qihao; Spasov, Krasimir A.; Zhang, Chunhui; Mothes, Walther; Crawford, Jason M.; Lindenbach, Brett D.; Uchil, Pradeep D.; Kumar, Priti; Jorgensen, William L.; Anderson, Karen S. 分享 收藏
A novel humanized mouse model recapitulates the unique TME found in patients with HIV-associated NSCLC Juric, Melani; Kaufmann, Gabriel; Zhu, Li; Ranjan, Kishu; Agrawal, Kriti; Rajendran, Barani Kumar; Rajashekar, Jyothi K.; Zhao, Hongyu; Kluger, Yuval; Emu, Brinda; Schalper, Kurt A.; Kumar, Priti; Flavell, Richard A.; Chiorazzi, Michael 分享 收藏
Blocking Fas signaling in adipose tissue ameliorates obesity-associated inflammation, insulin resistance, and hepatosteatosis Beloor, Jagadish; Ullah, Irfan; Kim, Jongkil; Choi, Changseon; Kim, Sunghwa; Chung, Kunho; Kr, Jyothi; Yi, Yujong; Rhim, Taiyoun; Kumar, Priti; Lee, Sang-Kyung 分享 收藏
Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells Behrens, Ryan T.; Rajashekar, Jyothi Krishnaswamy; Bruce, James W.; Evans III, Edward L.; Hansen, Amelia M.; Salazar-Quiroz, Natalia; Simons, Lacy M.; Ahlquist, Paul; Hultquist, Judd F.; Kumar, Priti; Sherer, Nathan M. 分享 收藏
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing Lyons, Danielle E.; Kumar, Priti; Roan, Nadia R.; Defechereux, Patricia A.; Feschotte, Cedric; Lange, Ulrike C.; Murthy, Niren; Sameshima, Pauline; Verdin, Eric; Ake, Julie A.; Parsons, Matthew S.; Nath, Avindra; Gianella, Sara; Smith, Davey M.; Kallas, Esper G.; Villa, Thomas J.; Strange, Richard; Mwesigwa, Betty; Furler O'Brien, Robert L.; Nixon, Douglas F.; Ndhlovu, Lishomwa C.; Valente, Susana T.; Ott, Melanie 分享 收藏
Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine 基于OMV的SARS-CoV-2疫苗的免疫原性和临床前功效 Grandi, Alberto; Tomasi, Michele; Ullah, Irfan; Bertelli, Cinzia; Vanzo, Teresa; Accordini, Silvia; Gagliardi, Assunta; Zanella, Ilaria; Benedet, Mattia; Corbellari, Riccardo; Di Lascio, Gabriele; Tamburini, Silvia; Caproni, Elena; Croia, Lorenzo; Rava, Micol; Fumagalli, Valeria; Di Lucia, Pietro; Marotta, Davide; Sala, Eleonora; Iannacone, Matteo; Kumar, Priti; Mothes, Walther; Uchil, Pradeep D.; Cherepanov, Peter; Bolognesi, Martino; Pizzato, Massimo; Grandi, Guido 分享 收藏
Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models Lorenzo, Maria M.; Marin-Lopez, Alejandro; Chiem, Kevin; Jimenez-Cabello, Luis; Ullah, Irfan; Utrilla-Trigo, Sergio; Calvo-Pinilla, Eva; Lorenzo, Gema; Moreno, Sandra; Ye, Chengjin; Park, Jun-Gyu; Matia, Alejandro; Brun, Alejandro; Sanchez-Puig, Juana M.; Nogales, Aitor; Mothes, Walther; Uchil, Pradeep D.; Kumar, Priti; Ortego, Javier; Fikrig, Erol; Martinez-Sobrido, Luis; Blasco, Rafael 分享 收藏
The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice Ullah, Irfan; Beaudoin-Bussieres, Guillaume; Symmes, Kelly; Cloutier, Marc; Ducas, Eric; Tauzin, Alexandra; Laumaea, Annemarie; Grunst, Michael W.; Dionne, Katrina; Richard, Jonathan; Begin, Philippe; Mothes, Walther; Kumar, Priti; Bazin, Renee; Finzi, Andres; Uchil, Pradeep D. 分享 收藏
HIV-1 Vpu restricts Fc-mediated effector functions in vivo HIV-1 Vpu在体内限制Fc介导的效应子功能 Prevost, Jeremie; Anand, Sai Priya; Rajashekar, Jyothi Krishnaswamy; Zhu, Li; Richard, Jonathan; Goyette, Guillaume; Medjahed, Halima; Gendron-Lepage, Gabrielle; Chen, Hung-Ching; Chen, Yaozong; Horwitz, Joshua A.; Grunst, Michael W.; Zolla-Pazner, Susan; Haynes, Barton F.; Burton, Dennis R.; Flavell, Richard A.; Kirchhoff, Frank; Hahn, Beatrice H.; Smith, Amos B.; Pazgier, Marzena; Nussenzweig, Michel C.; Kumar, Priti; Finzi, Andres 分享 收藏
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities 工程ACE2-Fc通过直接中和和Fc效应子活性对抗小鼠致死性SARS-CoV-2感染 Chen, Yaozong; Sun, Lulu; Ullah, Irfan; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Hederman, Andrew P.; Tolbert, William D.; Sherburn, Rebekah; Nguyen, Dung N.; Marchitto, Lorie; Ding, Shilei; Wu, Di; Luo, Yuhong; Gottumukkala, Suneetha; Moran, Sean; Kumar, Priti; Piszczek, Grzegorz; Mothes, Walther; Ackerman, Margaret E.; Finzi, Andres; Uchil, Pradeep D.; Gonzalez, Frank J.; Pazgier, Marzena 分享 收藏
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection Fc增强的NTD结合非中和抗体延迟病毒扩散，并与nAb协同保护小鼠免受致死性SARS-CoV-2感染 Beaudoin-Bussieres, Guillaume; Chen, Yaozong; Ullah, Irfan; Prevost, Jeremie; Tolbert, William D.; Symmes, Kelly; Ding, Shilei; Benlarbi, Mehdi; Gong, Shang Yu; Tauzin, Alexandra; Gasser, Romain; Chatterjee, Debashree; Vezina, Dani; Goyette, Guillaume; Richard, Jonathan; Zhou, Fei; Stamatatos, Leonidas; McGuire, Andrew T.; Charest, Hughes; Roger, Michel; Pozharski, Edwin; Kumar, Priti; Mothes, Walther; Uchil, Pradeep D.; Pazgier, Marzena; Finzi, Andres 分享 收藏
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern 两种广泛中和抗体针对SARS-CoV-2令人关注的新兴变体的结构基础和作用方式 Li, Wenwe; Chen, Yaozong; Prevost, Jeemie; Ullah, Irfan; Lu, Maoli; Gong, Shang Yu; Tauzin, Alexandra; Gasser, Romain; Vezina, Dani; Anand, Sai Priya; Goyette, Guillaume; Chaterjee, Debashree; Ding, Shilei; Tolbert, William D.; Grunst, Michael W.; Bo, Yuxia; Zhang, Shijian; Richard, Jonathan; Zhou, Fei; Huang, Rick K.; Esser, Lothar; Zeher, Allison; Cote, Marceline; Kumar, Priti; Sodroski, Joseph; Xia, Di; Uchil, Pradeep D.; Pazgier, Marzena; Finzi, Andres; Mothes, Walther 分享 收藏
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy 小鼠SARS-CoV-2感染的实时成像显示，中和抗体需要Fc功能才能获得最佳疗效 Ullah, Irfan; Prevost, Jeremie; Ladinsky, Mark S.; Stone, Helen; Lu, Maolin; Anand, Sai Priya; Beaudoin-Bussieres, Guillaume; Symmes, Kelly; Benlarbi, Mehdi; Ding, Shilei; Gasser, Romain; Fink, Corby; Chen, Yaozong; Tauzin, Alexandra; Goyette, Guillaume; Bourassa, Catherine; Medjahed, Halima; Mack, Matthias; Chung, Kunho; Wilen, Craig B.; Dekaban, Gregory A.; Dikeakos, Jimmy D.; Bruce, Emily A.; Kaufmann, Daniel E.; Stamatatos, Leonidas; McGuire, Andrew T.; Richard, Jonathan; Pazgier, Marzena; Bjorkman, Pamela J.; Mothes, Walther; Finzi, Andres; Kumar, Priti; Uchil, Pradeep D. 分享 收藏
In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission Haugh, Kelsey A.; Ladinsky, Mark S.; Ullah, Irfan; Stone, Helen M.; Pi, Ruoxi; Gilardet, Alexandre; Grunst, Michael W.; Kumar, Priti; Bjorkman, Pamela J.; Mothes, Walther; Uchil, Pradeep D. 分享 收藏
Long-acting and extended-release implant and nanoformulations with a synergistic antiretroviral two-drug combination controls HIV-1 infection in a humanized mouse model Beloor, Jagadish; Kudalkar, Shalley N.; Buzzelli, Gina; Yang, Fan; Mandl, Hanna K.; Rajashekar, Jyothi K.; Spasov, Krasimir A.; Jorgensen, William L.; Saltzman, W. Mark; Anderson, Karen S.; Kumar, Priti 分享 收藏
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