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L

Ludger J.E. Goeminne

Brigham and Women's Hospital and Harvard Medical School
H指数:21
被引数:1,355
浏览量:0

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荣誉奖项

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Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment

将蛋白质组学衰老时钟整合到2a期临床试验中支持同步的抗衰老评估

Nature Biotechnology
IF41.7
2026-09-070
OAAI
Alex Zhavoronkov; Fedor Galkin; Shan Chen; Feng Ren; Alex Aliper; Mikhail Durymanov; Denis Sidorenko; Hui Cui; Jing-Dong J. Han; Hao Xu; Xiaodong Liu; Zuojun Xu; Christoph Kuppe; M. Austin Argentieri; Kejun Ying; Ludger J. E. Goeminne; Mahdi Moqri; Alexander Tyshkovskiy; Vadim N. Gladyshev
Integrative epigenetics and transcriptomics identify aging genes in human blood

整合表观遗传学和转录组学鉴定人类血液中的衰老基因

Nature Communications
IF15.7
2026-01-190
OAAI
Mahdi Moqri; Kejun Ying; Jesse R. Poganik; Chiara Herzog; Qingwen Chen; Mehrnoosh Emamifar; Alexander Tyshkovskiy; Alec Eames; Jure Mur; Dmitrii Glubokov; Benyamin Matei-Dediu; Ludger Goeminne; Wayne Mitchell; Daniel L. McCartney; Lucas A. Salas; Riccardo E. Marioni; Jessica A. Lasky-Su; Michael P. Snyder; Vadim N. Gladyshev
A unified framework for systematic curation and evaluation of aging biomarkers

一个用于衰老生物标志物系统性整理与评估的统一框架

Nature Aging
IF19.4
2025-11-040
PRE
Kejun Ying; Seth Paulson; Alec Eames; Alexander Tyshkovskiy; Siyuan Li; Nir Eynon; Macsue Jacques; Robin Grolaux; Kirsten Seale; Erik Jacques; Ludger J. E. Goeminne; Andrea Cipriano; Martin Perez-Guevara; Mehrnoosh Emamifar; Maximiliano Casas Martínez; Dayoon Kwon; Anna Kosheleva; Michael Snyder; Dane Gobel; Chiara Herzog; Daniel L. McCartney; Riccardo E. Marioni; Jessica Lasky-Su; Jesse R. Poganik; Mahdi Moqri; Vadim N. Gladyshev
Challenges and recommendations for the translation of biomarkers of aging

衰老生物标志物翻译的挑战和建议

NATURE AGING
IF19.4
2024-09-160
PRE
Herzog, Chiara M. S.; Goeminne, Ludger J. E.; Poganik, Jesse R.; Barzilai, Nir; Belsky, Daniel W.; Betts-LaCroix, Joe; Chen, Brian H.; Chen, Michelle; Cohen, Alan A.; Cummings, Steven R.; Fedichev, Peter O.; Ferrucci, Luigi; Fleming, Alexander; Fortney, Kristen; Furman, David; Gorbunova, Vera; Higgins-Chen, Albert; Hood, Lee; Horvath, Steve; Justice, Jamie N.; Kiel, Douglas P.; Kuchel, George A.; Lasky-Su, Jessica; Lebrasseur, Nathan K.; Maier, Andrea B.; Schilling, Birgit; Sebastiano, Vittorio; Slagboom, P. Eline; Snyder, Michael P.; Verdin, Eric; Widschwendter, Martin; Zhavoronkov, Alex; Moqri, Mahdi; Gladyshev, Vadim N.
Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-05-1721
PRE
Lima, Tanes I.; Laurila, Pirkka-Pekka; Wohlwend, Martin; Morel, Jean David; Goeminne, Ludger J. E.; Li, Hao; Romani, Mario; Li, Xiaoxu; Oh, Chang-Myung; Park, Dohyun; Rodriguez-Lopez, Sandra; Ivanisevic, Julijana; Gallart-Ayala, Hector; Crisol, Barbara; Delort, Florence; Batonnet-Pichon, Sabrina; Silveira, Leonardo R.; Venkata, Lakshmi Sankabattula Pavani Veera; Padala, Anil K.; Jain, Suresh; Auwerx, Johan
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression

遗传背景影响线粒体功能障碍和NASH进展的易感性

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2023-02-1415
OAAI
Benegiamo, Giorgia; von Alvensleben, Giacomo V. G.; Rodriguez-Lopez, Sandra; Goeminne, Ludger J. E.; Bachmann, Alexis M.; Morel, Jean-David; Broeckx, Ellen; Ma, Jing Ying; Carreira, Vinicius; Youssef, Sameh A.; Azhar, Nabil; Reilly, Dermot F.; D'Aquino, Katharine; Mullican, Shannon; Bou-Sleiman, Maroun; Auwerx, Johan
COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

COX7A2L遗传变异决定了小鼠和人类的心肺适应性

NATURE METABOLISM
IF20.8
2022-10-1716
OAAI
Benegiamo, Giorgia; Sleiman, Maroun Bou; Wohlwend, Martin; Rodriguez-Lopez, Sandra; Goeminne, Ludger J. E.; Laurila, Pirkka-Pekka; Klevjer, Marie; Salonen, Minna K.; Lahti, Jari; Jha, Pooja; Cogliati, Sara; Enriquez, Jose Antonio; Brumpton, Ben M.; Bye, Anja; Eriksson, Johan G.; Auwerx, Johan
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
CELL METABOLISM
IF30.9
2022-10-0114
OAAI
Li, Hao; Perino, Alessia; Huang, Qingyao; Von Alvensleben, Giacomo V. G.; Banaei-Esfahani, Amir; Velazquez-Villegas, Laura A.; Gariani, Karim; Korbelius, Melanie; Sleiman, Maroun Bou; Imbach, Jeromine; Sun, Yu; Li, Xiaoxu; Bachmann, Alexis; Goeminne, Ludger J. E.; Gallart-Ayala, Hector; Williams, Evan G.; Ivanisevic, Julijana; Auwerx, Johan; Schoonjans, Kristina
Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism
SCIENCE ADVANCES
IF12.5
2022-07-2911
OAAI
Katashima, Carlos Kiyoshi; Micheletti, Thayana de Oliveira; Braga, Renata Rosseto; Gaspar, Rodrigo Stellzer; Goeminne, Ludger J. E.; Moura-Assis, Alexandre; Crisol, Barbara Moreira; Bricola, Rafael S.; Silva, Vagner Ramon R.; Ramos, Camila de Oliveira; da Rocha, Alisson L.; Tavares, Mariana Rosolen; Simabuco, Fernando Moreira; Matheus, Valquiria Aparecida; Buscaratti, Lucas; Marques-Souza, Henrique; Pazos, Patricia; Gonzalez-Touceda, David; Tovar, Sulay; Garcia, Maria del Carmen; Rosa Neto, Jose Cesar; Curi, Rui; Hirabara, Sandro Massao; Brum, Patricia Chakur; Prada, Patricia Oliveira; de Moura, Leandro P.; Pauli, Jose Rodrigo; da Silva, Adelino S. R.; Cintra, Dennys Esper; Velloso, Licio A.; Ropelle, Eduardo Rochete

研究方向

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J
Johan Auwerx
H 指数:183论文数:914被引数:12.5万
V
Vadim N. Gladyshev
H 指数:123论文数:791被引数:5.3万
M
Mahdi Moqri
H 指数:19论文数:77被引数:2,017
L
Lieven Clement
H 指数:29论文数:174被引数:4,953
H
Héctor Gallart‐Ayala
H 指数:36论文数:139被引数:4,190
M
Martin Wohlwend
H 指数:18论文数:51被引数:956
B
Bárbara Crisol
H 指数:15论文数:50被引数:629
T
Tyshkovskiy, Alexander
H 指数:0论文数:6被引数:3
P
Pirkka‐Pekka Laurila
H 指数:22论文数:61被引数:1,497
J
Julijana Ivanišević
H 指数:40论文数:145被引数:1.0万