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Mahdi Moqri

Brigham and Women's Hospital and Harvard Medical School
H指数:19
被引数:2,017
浏览量:0

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Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment

将蛋白质组学衰老时钟整合到2a期临床试验中支持同步的抗衰老评估

Nature Biotechnology
IF41.7
2026-09-070
OAAI
Alex Zhavoronkov; Fedor Galkin; Shan Chen; Feng Ren; Alex Aliper; Mikhail Durymanov; Denis Sidorenko; Hui Cui; Jing-Dong J. Han; Hao Xu; Xiaodong Liu; Zuojun Xu; Christoph Kuppe; M. Austin Argentieri; Kejun Ying; Ludger J. E. Goeminne; Mahdi Moqri; Alexander Tyshkovskiy; Vadim N. Gladyshev
Immune aging biomarkers for clinical trials

用于临床试验的免疫衰老生物标志物

Nature Medicine
IF50
2026-07-030
PRE
Andrea Cipriano; Jamie Justice; Jesse R. Poganik; Mahdi Moqri; Omar O. Abudayyeh; Jonathan Gootenberg; Laura Haynes; Yotam Levin; Daniel E. Martin-Herranz; Arne N. Akbar; Joan Mannick; Graham Pawelec; Shai S. Shen-Orr; John Tsang; Wolfgang Wagner; Miriam Merad; Sacha Gnjatic; Alfred Gellhorn; Michael J. Corley; George A. Kuchel; Luigi Ferrucci; David Furman; Chiara M. S. Herzog
Meta-analysis of DNA methylation aging signatures in 17 human tissues

17种人类组织中DNA甲基化衰老标志物的荟萃分析

Nature Aging
IF19.4
2026-06-260
OAAI
Macsue Jacques; Kirsten Seale; Sarah Voisin; Anna Lysenko; Robin Grolaux; Bernadette Jones-Freeman; Severine Lamon; Mandhri Abeysooriya; Itamar Levinger; Carlie Bauer; Adam P. Sharples; Aino Heikkinen; Elina Sillanpaa; Miina Ollikainen; Cassandra Smith; James R. Broatch; Navabeh Zarekookandeh; Linn Gillberg; Ida Blom; Jesse R. Poganik; Mahdi Moqri; Vadim N. Gladyshev; Matthew Taper; Cassandra Malecki; Sean Lal; Nathalie Saurat; Steve Horvath; Andrew Teschendorff; Nir Eynon
Integrative epigenetics and transcriptomics identify aging genes in human blood

整合表观遗传学和转录组学鉴定人类血液中的衰老基因

Nature Communications
IF15.7
2026-01-190
OAAI
Mahdi Moqri; Kejun Ying; Jesse R. Poganik; Chiara Herzog; Qingwen Chen; Mehrnoosh Emamifar; Alexander Tyshkovskiy; Alec Eames; Jure Mur; Dmitrii Glubokov; Benyamin Matei-Dediu; Ludger Goeminne; Wayne Mitchell; Daniel L. McCartney; Lucas A. Salas; Riccardo E. Marioni; Jessica A. Lasky-Su; Michael P. Snyder; Vadim N. Gladyshev
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes

14种表观时钟与174种新发疾病结局的客观比较

Nature Communications
IF15.7
2025-12-160
OAAI
Christos Mavrommatis; Daniel W. Belsky; Kejun Ying; Mahdi Moqri; Archie Campbell; Anne Richmond; Vadim N. Gladyshev; Tamir Chandra; Daniel L. McCartney; Riccardo E. Marioni
Epigenetic age predictors for non-invasive assessment of human skin

非侵入性评估人类皮肤的表观遗传年龄预测因子

npj Aging
IF6
2025-12-120
OAAI
Angel Menendez Vazquez; Dimitris Katsanos; Miruna Vasile; Andrew Graham; Victoria Dyster; Shakiba Kaveh; Mahdi Moqri; Cristiana Banila
A unified framework for systematic curation and evaluation of aging biomarkers

一个用于衰老生物标志物系统性整理与评估的统一框架

Nature Aging
IF19.4
2025-11-040
PRE
Kejun Ying; Seth Paulson; Alec Eames; Alexander Tyshkovskiy; Siyuan Li; Nir Eynon; Macsue Jacques; Robin Grolaux; Kirsten Seale; Erik Jacques; Ludger J. E. Goeminne; Andrea Cipriano; Martin Perez-Guevara; Mehrnoosh Emamifar; Maximiliano Casas Martínez; Dayoon Kwon; Anna Kosheleva; Michael Snyder; Dane Gobel; Chiara Herzog; Daniel L. McCartney; Riccardo E. Marioni; Jessica Lasky-Su; Jesse R. Poganik; Mahdi Moqri; Vadim N. Gladyshev
Profiling Epigenetic Aging at Cell-Type Resolution Through Long-Read Sequencing

通过长读长测序在细胞类型分辨率下进行表观遗传衰老分析

Aging Cell
IF7.1
2025-07-020
OA
Alec Eames; Mahdi Moqri; Jesse R. Poganik; Vadim N. Gladyshev
Digital biomarkers of ageing for monitoring physiological systems in community-dwelling adults

社区居住成人中用于监测生理系统的衰老数字生物标志物

lancet healthy longevity
IF0
2025-06-120
OA
Jessica K Lu; Weilan Wang; Muhammad Daniel Azlan Mahadzir; Jesse R Poganik; Mahdi Moqri; Chiara Herzog; Eric Verdin; Vittorio Sebastiano; Vadim N Gladyshev; Andrea B Maier
Plasma protein-based organ-specific aging and mortality models unveil diseases as accelerated aging of organismal systems

基于血浆蛋白的器官特异性衰老和死亡率模型揭示了疾病作为生物系统加速衰老的现象

CELL METABOLISM
IF30.9
2025-01-018
PRE
Goeminne, Ludger J. E.; Vladimirova, Anastasiya; Eames, Alec; Tyshkovskiy, Alexander; Argentieri, M. Austin; Ying, Kejun; Moqri, Mahdi; Gladyshev, Vadim N.
Disagreement on foundational principles of biological aging
PNAS NEXUS
IF3.8
2024-12-038
OAAI
Gladyshev, Vadim N.; Anderson, Benjamin; Barlit, Hanna; Barre, Benjamin; Beck, Samuel; Behrouz, Bahareh; Belsky, Daniel W.; Chaix, Amandine; Chamoli, Manish; Chen, Brian H.; Cheng, Kaiyang; Chuprin, Jane; Churchill, Gary A.; Cipriano, Andrea; Colville, Alex; Deelen, Joris; Deigin, Yuri; Edmonds, KeHuan K.; English, Bradley W.; Fang, Ruogu; Florea, Michael; Gershteyn, Iosif M.; Gill, Diljeet; Goetz, Laura H.; Gorbunova, Vera; Griffin, Patrick T.; Horvath, Steve; Jensen, Martin Borch; Jin, Xin; Jovanovska, Sara; Kajderowicz, Kathrin M.; Kasahara, Tomoko; Kerepesi, Csaba; Kulkarni, Subhash; Labunskyy, Vyacheslav M.; Levine, Morgan E.; Libert, Sergiy; Lu, J. Yuyang; Lu, Yuancheng Ryan; Marioni, Riccardo E.; McCoy, Brianah M.; Mitchell, Wayne; Moqri, Mahdi; Nasirian, Farzaneh; Niimi, Peter; Oh, Hamilton Se-Hwee; Okundaye, Brian; Parkhitko, Andrey A.; Peshkin, Leonid; Petljak, Mia; Poganik, Jesse R.; Pridham, Glen; Promislow, Daniel E. L.; Prusisz, Weronika; Quiniou, Margaux; Raj, Ken; Richard, Daniel; Ricon, Jose Luis; Rutledge, Jarod; Scheibye-Knudsen, Morten; Schork, Nicholas J.; Seluanov, Andrei; Shadpour, Michael; Shindyapina, Anastasia V.; Shuken, Steven R.; Sivakumar, Sruthi; Stoeger, Thomas; Sugiura, Ayumu; Sutton, Nadia R.; Suvorov, Alexander; Tarkhov, Andrei E.; Teeling, Emma C.; Trapp, Alexandre; Tyshkovskiy, Alexander; Unfried, Maximilian; Ward-Caviness, Cavin K.; Yim, Sun Hee; Ying, Kejun; Yunes, Jeffrey; Zhang, Bohan; Zhavoronkov, Alex
Depletion of loss-of-function germline mutations in centenarians reveals longevity genes
NATURE COMMUNICATIONS
IF15.7
2024-10-190
OAAI
Ying, Kejun; Castro, Jose P.; Shindyapina, Anastasia V.; Tyshkovskiy, Alexander; Moqri, Mahdi; Goeminne, Ludger J. E.; Milman, Sofiya; Zhang, Zhengdong D.; Barzilai, Nir; Gladyshev, Vadim N.
Challenges and recommendations for the translation of biomarkers of aging

衰老生物标志物翻译的挑战和建议

NATURE AGING
IF19.4
2024-09-160
PRE
Herzog, Chiara M. S.; Goeminne, Ludger J. E.; Poganik, Jesse R.; Barzilai, Nir; Belsky, Daniel W.; Betts-LaCroix, Joe; Chen, Brian H.; Chen, Michelle; Cohen, Alan A.; Cummings, Steven R.; Fedichev, Peter O.; Ferrucci, Luigi; Fleming, Alexander; Fortney, Kristen; Furman, David; Gorbunova, Vera; Higgins-Chen, Albert; Hood, Lee; Horvath, Steve; Justice, Jamie N.; Kiel, Douglas P.; Kuchel, George A.; Lasky-Su, Jessica; Lebrasseur, Nathan K.; Maier, Andrea B.; Schilling, Birgit; Sebastiano, Vittorio; Slagboom, P. Eline; Snyder, Michael P.; Verdin, Eric; Widschwendter, Martin; Zhavoronkov, Alex; Moqri, Mahdi; Gladyshev, Vadim N.
Transcriptional and epigenetic characterization of a new in vitro platform to model the formation of human pharyngeal endoderm
GENOME BIOLOGY
IF9.4
2024-08-080
OAAI
Cipriano, Andrea; Colantoni, Alessio; Calicchio, Alessandro; Fiorentino, Jonathan; Gomes, Danielle; Moqri, Mahdi; Parker, Alexander; Rasouli, Sajede; Caldwell, Matthew; Briganti, Francesca; Roncarolo, Maria Grazia; Baldini, Antonio; Weinacht, Katja G.; Tartaglia, Gian Gaetano; Sebastiano, Vittorio
PRC2-AgeIndex as a universal biomarker of aging and rejuvenation

PRC2-AgeIndex作为衰老和复兴的普遍生物标志物

NATURE COMMUNICATIONS
IF15.7
2024-07-162
OAAI
Moqri, Mahdi; Cipriano, Andrea; Simpson, Daniel J.; Rasouli, Sajede; Murty, Tara; de Jong, Tineke Anna; Nachun, Daniel; Brandine, Guilherme de Sena; Ying, Kejun; Tarkhov, Andrei; Aberg, Karolina A.; van den Oord, Edwin; Zhou, Wanding; Smith, Andrew; Mackall, Crystal; Gladyshev, Vadim N.; Horvath, Steve; Snyder, Michael P.; Sebastiano, Vittorio
Nature of epigenetic aging from a single-cell perspective

从单细胞角度看表观遗传衰老的本质

NATURE AGING
IF19.4
2024-05-0910
PRE
Tarkhov, Andrei E.; Lindstrom-Vautrin, Thomas; Zhang, Sirui; Ying, Kejun; Moqri, Mahdi; Zhang, Bohan; Tyshkovskiy, Alexander; Levy, Orr; Gladyshev, Vadim N.
Validation of biomarkers of aging

衰老生物标志物的验证

NATURE MEDICINE
IF50
2024-02-1432
OA
Moqri, Mahdi; Herzog, Chiara; Poganik, Jesse R.; Ying, Kejun; Justice, Jamie N.; Belsky, Daniel W.; Higgins-Chen, Albert T.; Chen, Brian H.; Cohen, Alan A.; Fuellen, Georg; Haegg, Sara; Marioni, Riccardo E.; Widschwendter, Martin; Fortney, Kristen; Fedichev, Peter O.; Zhavoronkov, Alex; Barzilai, Nir; Lasky-Su, Jessica; Kiel, Douglas P.; Kennedy, Brian K.; Cummings, Steven; Slagboom, P. Eline; Verdin, Eric; Maier, Andrea B.; Sebastiano, Vittorio; Snyder, Michael P.; Gladyshev, Vadim N.; Horvath, Steve; Ferrucci, Luigi
Causality-enriched epigenetic age uncouples damage and adaptation

因果关系丰富的表观遗传年龄使损伤和适应解耦

NATURE AGING
IF19.4
2024-01-1924
OA
Ying, Kejun; Liu, Hanna; Tarkhov, Andrei E.; Sadler, Marie C.; Lu, Ake T.; Moqri, Mahdi; Horvath, Steve; Kutalik, Zoltan; Shen, Xia; Gladyshev, Vadim N.
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (vol 4, 14, 2024)
NATURE AGING
IF19.4
2024-01-040
OA
Cipriano, Andrea; Moqri, Mahdi; Maybury-Lewis, Sun Y.; Rogers-Hammond, Ryan; de Jong, Tineke Anna; Parker, Alexander; Rasouli, Sajede; Scholer, Hans Robert; Sinclair, David A.; Sebastiano, Vittorio
Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming
NATURE AGING
IF19.4
2023-12-159
OA
Cipriano, Andrea; Moqri, Mahdi; Maybury-Lewis, Sun Y.; Rogers-Hammond, Ryan; de Jong, Tineke Anna; Parker, Alexander; Rasouli, Sajede; Schoeler, Hans Robert; Sinclair, David A.; Sebastiano, Vittorio

研究方向

暂未获取到该数据
V
Vadim N. Gladyshev
H 指数:123论文数:791被引数:5.3万
K
Kejun Ying
H 指数:19论文数:53被引数:1,154
J
Jesse R. Poganik
H 指数:20论文数:67被引数:2,890
V
Vittorio Sebastiano
H 指数:39论文数:101被引数:9,724
M
M Snyder
H 指数:210论文数:3,271被引数:19.9万
S
Steve Horvath
H 指数:150论文数:947被引数:13.7万
C
Chiara Herzog
H 指数:14论文数:136被引数:1,568
L
Ludger J.E. Goeminne
H 指数:21论文数:71被引数:1,355
T
Tyshkovskiy, Alexander
H 指数:0论文数:6被引数:3
A
Andrea Cipriano
H 指数:13论文数:25被引数:753