Mehdi Mobli - Publications, H-index & Citations

Mehdi Mobli

the university of queensland

47H指数

219论文数

6.6K被引数

收录论文 76

发表时间

Antigen-Detected NMR for Minimal Epitope Engineering and Structure-Guided Selection of a Na_V1.7-Selective Nanobody 抗原检测NMR技术用于最小表位工程改造和结构指导的Na_V1.7选择性纳米抗体的筛选

Advanced Science

IF14.1

2026-09-07

OAAI

Junyu Liu; Wanlin Chen; Ben Cristofori-Armstrong; Theo Crawford; Kai-En Chen; Peng Xie; Rainbow Wing Bo Chan; Yifei Zhu; Mimi Golder; Anneka Pereira Schmidt; Jennifer D. Naughton; Nicholas D. Condon; Åsa Andersson; Farhad Dehkhoda; Kirsten L. McMahon; Tabea Klasfauseweh; Ashvriya Thapa; Hue Tran; Poanna Tran; Sina Jami; Lotten Ragnarsson; Sebastian G. B. Furness; Jennifer R. Deuis; Brett M. Collins; Wai-Hong Tham; Indira Prasadam; Irina Vetter; Mehdi Mobli

The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1b 纳米抗体Nb.C1增强了人酸敏感离子通道1a和1b

European Journal of Pharmacology

IF4.7

2026-04-07

PREAI

Mimi Golder; Neville J. Butcher; Jennifer D. Naughton; Junyu Liu; Theo Crawford; Lachlan D. Rash; Mehdi Mobli; Ben Cristofori-Armstrong

The Isolated Thumb Domain of Acid-Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding Studies 酸性离子通道分离的拇指结构域形成最小折叠单元，实现配体结合研究

Angewandte Chemie International Edition

IF16.9

2026-03-25

OAAI

Biswa P. Mishra; Ben Cristofori-Armstrong; Elena Budusan; Mimi Golder; Neville J. Butcher; Junyu Liu; Theo Crawford; Yanni K.-Y. Chin; Anneka Pereira Schmidt; Xinying Jia; Taylor B. Smallwood; Richard J. Clark; Jan P. Wurm; Lachlan D. Rash; Mehdi Mobli

Ancient origin and dynamic evolution of bivalent spider toxins 二价蜘蛛毒素的古老起源与动态演化

Molecular Biology and Evolution

IF5.3

2026-03-24

OAAI

Robin A Araya; Marius F Maurstad; David T Wilson; Lachlan D Rash; Mehdi Mobli; Kjetill S Jakobsen; Eivind A B Undheim; null; null

Topological isomers of a potent wound healing peptide: Structural insights and implications for bioactivity 一种强效伤口愈合肽的拓扑异构体：结构洞察及其对生物活性的影响

Journal of Biological Chemistry

IF3.9

2025-07-01

OAAI

Tiziano Raffaelli; David T. Wilson; Mehdi Mobli; Michael J. Smout; Guangzu Zhao; Rozita Takjoo; Paramjit S. Bansal; Rilei Yu; Zixuan Zhang; Alex Loukas; Norelle L. Daly

Refining the NaV1.7 pharmacophore of a class of venom-derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS LETTERS

IF3

2025-03-01

OAAI

Sharma, Gagan; Deuis, Jennifer R.; Jia, Xinying; Crawford, Theo; Rahnama, Sassan; Undheim, Eivind A. B.; Vetter, Irina; Chin, Yanni K. -Y.; Mobli, Mehdi

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2024-02-28

OAAI

Rahaman, Md. Habibur; Thygesen, Sara J.; Maxwell, Michael J.; Kim, Hyoyoung; Mudai, Prerna; Nanson, Jeffrey D.; Jia, Xinying; Vajjhala, Parimala R.; Hedger, Andrew; Vetter, Irina; Haselhorst, Thomas; Robertson, Avril A. B.; Dymock, Brian; Ve, Thomas; Mobli, Mehdi; Stacey, Katryn J.; Kobe, Bostjan

Structural Basis of the Bivalency of the TRPV1 Agonist DkTx TRPV1激动剂DkTx的二价结构基础

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-12-12

OAAI

Ramanujam, Venkatraman; Crawford, Theo; Cristofori-Armstrong, Ben; Deuis, Jennifer R.; Jia, Xinying; Maxwell, Michael J.; Jami, Sina; Ma, Linlin; Vetter, Irina; Mobli, Mehdi

Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH

ACS OMEGA

IF4.3

2023-07-11

OAAI

Tran, Poanna; Crawford, Theo; Ragnarsson, Lotten; Deuis, Jennifer R.; Mobli, Mehdi; Sharpe, Simon J.; Schroeder, Christina I.; Vetter, Irina

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

NATURE COMMUNICATIONS

IF15.7

2023-04-28

OAAI

Jami, Sina; Deuis, Jennifer R.; Klasfauseweh, Tabea; Cheng, Xiaoyang; Kurdyukov, Sergey; Chung, Felicity; Okorokov, Andrei L.; Li, Shengnan; Zhang, Jiangtao; Ben Cristofori-Armstrong; Israel, Mathilde R.; Ju, Robert J.; Robinson, Samuel D.; Zhao, Peng; Ragnarsson, Lotten; Andersson, Asa; Tran, Poanna; Schendel, Vanessa; McMahon, Kirsten L.; Tran, Hue N. T.; Chin, Yanni K. -Y.; Zhu, Yifei; Liu, Junyu; Crawford, Theo; Purushothamvasan, Saipriyaa; Habib, Abdella M.; Andersson, David A.; Rash, Lachlan D.; Wood, John N.; Zhao, Jing; Stehbens, Samantha J.; Mobli, Mehdi; Leffler, Andreas; Jiang, Daohua; Cox, James J.; Waxman, Stephen G.; Dib-Hajj, Sulayman D.; Gregory Neely, G.; Durek, Thomas; Vetter, Irina

Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation

COMMUNICATIONS CHEMISTRY

IF6.2

2023-03-04

OAAI

Jia, Xinying; Chin, Yanni K. -Y.; Zhang, Alan H. H.; Crawford, Theo; Zhu, Yifei; Fletcher, Nicholas L. L.; Zhou, Zihan; Hamilton, Brett R. R.; Stroet, Martin; Thurecht, Kristofer J. J.; Mobli, Mehdi

Designing antimicrobial peptides using deep learning and molecular dynamic simulations 使用深度学习和分子动力学模拟设计抗菌肽

BRIEFINGS IN BIOINFORMATICS

IF7.7

2023-03-01

PREAI

Cao, Qiushi; Ge, Cheng; Wang, Xuejie; Harvey, Peta J.; Zhang, Zixuan; Ma, Yuan; Wang, Xianghong; Jia, Xinying; Mobli, Mehdi; Craik, David J.; Jiang, Tao; Yang, Jinbo; Wei, Zhiqiang; Wang, Yan; Chang, Shan; Yu, Rilei

Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-02-07

PREAI

Bartling, Christian R. O.; Alexopoulou, Flora; Kuschert, Sarah; Chin, Yanni K. -Y.; Jia, Xinying; Sereikaite, Vita; Ozcelik, Dennis; Jensen, Thomas M.; Jain, Palash; Nygaard, Mads M.; Harpsoe, Kasper; Gloriam, David E.; Mobli, Mehdi; Stromgaard, Kristian

Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes

SCIENTIFIC REPORTS

IF3.9

2022-07-04

OAAI

Mohanty, Biswaranjan; Orts, Julien; Wang, Geqing; Nebl, Stefan; Alwan, Wesam S.; Doak, Bradley C.; Williams, Martin L.; Heras, Begona; Mobli, Mehdi; Scanlon, Martin J.

The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-05-01

OAAI

Liu, Liping; Lucas, Richard M.; Nanson, Jeffrey D.; Li, Yan; Whitfield, Jason; Curson, James E. B.; Tuladhar, Neeraj; Alexandrov, Kirill; Mobli, Mehdi; Sweet, Matthew J.; Kobe, Bostjan; Stow, Jennifer L.; Luo, Lin

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

NEURON

IF15

2021-04-01

162

OAAI

Figley, Matthew D.; Gu, Weixi; Nanson, Jeffrey D.; Shi, Yun; Sasaki, Yo; Cunnea, Katie; Malde, Alpeshkumar K.; Jia, Xinying; Luo, Zhenyao; Saikot, Forhad K.; Mosaiab, Tamim; Masic, Veronika; Holt, Stephanie; Hartley-Tassell, Lauren; McGuinness, Helen Y.; Manik, Mohammad K.; Bosanac, Todd; Landsberg, Michael J.; Kerry, Philip S.; Mobli, Mehdi; Hughes, Robert O.; Milbrandt, Jeffrey; Kobe, Bostjan; DiAntonio, Aaron; Ve, Thomas

Recombinant production, bioconjugation and membrane binding studies of Pn3a, a selective NaV1.7 inhibitor

BIOCHEMICAL PHARMACOLOGY

IF5.6

2020-11-01

PREAI

Sharma, Gagan; Deuis, Jennifer R.; Jia, Xinying; Mueller, Alexander; Vetter, Irina; Mobli, Mehdi

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

NATURE COMMUNICATIONS

IF15.7

2020-06-23

123

OAAI

Elliott, Alysha G.; Huang, Johnny X.; Neve, Soren; Zuegg, Johannes; Edwards, Ingrid A.; Cain, Amy K.; Boinett, Christine J.; Barquist, Lars; Lundberg, Carina Vingsbo; Steen, Jason; Butler, Mark S.; Mobli, Mehdi; Porter, Kaela M.; Blaskovich, Mark A. T.; Lociuro, Sergio; Strandh, Magnus; Cooper, Matthew A.

Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-05-12

OAAI

Pineda, Sandy S.; Chin, Yanni K. -Y.; Undheim, Eivind A. B.; Senff, Sebastian; Mobli, Mehdi; Dauly, Claire; Escoubas, Pierre; Nicholson, Graham M.; Kaas, Quentin; Guo, Shaodong; Herzig, Volker; Mattick, John S.; King, Glenn F.

Residual Dipolar Couplings for Resolving Cysteine Bridges in Disulfide-Rich Peptides

FRONTIERS IN CHEMISTRY

IF4.2

2020-01-22

OAAI

Ramanujam, Venkatraman; Shen, Yang; Ying, Jinfa; Mobli, Mehdi

研究方向