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Frank Buchholz

TUD Dresden University of Technology

63H指数
326论文数
1.7W被引数
收录论文 121
发表时间
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Antibody-TLR3 agonist-conjugates program the tumor microenvironment and induce immune responses leading to tumor regression in experimental EGFRvIII-positive glioma抗体-TLR3激动剂偶联物调控肿瘤微环境并诱导免疫反应，导致实验性EGFRvIII阳性胶质瘤的肿瘤消退
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-09-22
err0
errOAAI
errAlexander Hagstotz; Isabell Schau; Michael Seifert; Duran Sürün; Stefan Zimmermann; Frank Buchholz; Luise Rupp; Rebekka Wehner; Marc Schmitz; Gabriele Schackert; Ilker Eyüpoglu; Achim Temme
err分享
err收藏
A retargeted recombinase for precise insertion of large DNA靶向重组酶用于大片段DNA的精确插入
errNature Biotechnology
IF41.7
err2026-06-29
err0
PREAI
errFrank Buchholz
err分享
err收藏
Knock Out of miRNA-30a-5p and Reconstitution of the Actin Network Dynamics Partly Restores the Impaired Terminal Erythroid Differentiation during Blood Pharming敲除miRNA-30a-5p并重建肌动蛋白网络动力学，部分恢复了血液放血过程中受损的终末红系分化
errStem Cell Reviews and Reports
IF4.2
err2025-08-26
err0
errOAAI
errJessica Thiel; Duran Sürün; Desiree C. Brändle; Madeleine Teichert; Stephan R. Künzel; Ulrike Friedrich; Andreas Dahl; Kristin Schubert; Ignacy Rzagalinski; Andrej Shevchenko; Sofia Traikov; Peter Mirtschink; Lisa Wagenführ; Frank Buchholz; Kristina Hölig; Torsten Tonn; Romy Kronstein-Wiedemann
err分享
err收藏
A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs一种用于纠正癌症驱动基因突变的碱基编辑平台揭示了保守的p53转录程序
errGenome Biology
IF9.4
err2025-08-25
err0
PREAI
errPascal Wang; Rituparno Sen; Frank Buchholz; Shady Sayed
err分享
err收藏
A pooled CRISPR screen identifies the Tα2 enhancer element as a driver of TRA expression in a subset of mature human T lymphocytes一个混合型CRISPR筛选鉴定了Tα2增强子元件作为在部分成熟人T淋巴细胞中驱动TRA表达的驱动因素。
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-03-14
err0
errOAAI
errSchoenberg, Pascal Y.; Munoz-Ovalle, Angela; Paszkowski-Rogacz, Maciej; Crespo, Eugenia; Surun, Duran; Feldmann, Anja; Buchholz, Frank
err分享
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Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/CMethylstat通过靶向组蛋白去甲基化酶JMJD1B/C，使卵巢癌细胞对PARP抑制剂产生敏感性。
errCANCER GENE THERAPY
IF5
err2025-02-06
err0
errOAAI
errSchwarz, Franziska Maria; Klotz, Daniel Martin; Yang, Ruming; Brux, Melanie; Buchholz, Frank; Harb, Hani; Link, Theresa; Wimberger, Pauline; Theis, Mirko; Kuhlmann, Jan Dominik
err分享
err收藏
Characterization of immortalized bone marrow erythroid progenitor adult (imBMEP-A)-The - The fi rst inducible immortalized red blood cell progenitor cell line derived from bone marrow CD71-positive cells永生化骨髓红系祖细胞成体 (imbmep-a) 的表征-来自骨髓CD71-positive细胞的第一个可诱导的永生化红细胞祖细胞系
errCYTOTHERAPY
IF3.2
err2024-11-01
err0
errOAAI
errKronstein-Wiedemann, Romy; Thiel, Jessica; Sueruen, Duran; Teichert, Madeleine; Kuenzel, Stephan R.; Zimmermann, Stefan; Wagenfuehr, Lisa; Buchholz, Frank; Tonn, Torsten
err分享
err收藏
Selective regulation of aspartyl intramembrane protease activity by calnexin
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-10-26
err0
errOAAI
errContreras, Whendy; Groenendyk, Jody; Gentzel, Marc; Schoenberg, Pascal Y.; Buchholz, Frank; Michalak, Marek; Schroeder, Bernd; Mentrup, Torben
err分享
err收藏
Engineering spacer specificity of the Cre/loxP system
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-06-13
err0
errOAAI
errHoersten, Jenna; Ruiz-Gomez, Gloria; Paszkowski-Rogacz, Maciej; Gilioli, Giorgio; Guillem-Gloria, Pedro Manuel; Lansing, Felix; Pisabarro, M. Teresa; Buchholz, Frank
err分享
err收藏
Antibody-TLR3 agonist-conjugates induce innate immune responses and immune memory eradicating experimental EGFRvIII-positive tumors
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errTemme, Achim; Hagstotz, Alexander; Schau, Isabell; Seifert, Michael; Surun, Duran; Zimmermann, Stefan; Buchholz, Frank; Rupp, Luise; Wehner, Rebekka; Schmitz, Marc; Schackert, Gabriele; Eyupoglu, Ilker Y.
err分享
err收藏
Activation of recombinases at specific DNA loci by zinc-finger domain insertions
errNATURE BIOTECHNOLOGY
IF41.7
err2024-01-31
err4
errOAAI
errMukhametzyanova, Liliya; Schmitt, Lukas Theo; Torres-Rivera, Julia; Rojo-Romanos, Teresa; Lansing, Felix; Paszkowski-Rogacz, Maciej; Hollak, Heike; Brux, Melanie; Augsburg, Martina; Schneider, Paul Martin; Buchholz, Frank
err分享
err收藏
Nucleolar protein TAAP1/C22orf46 confers pro-survival signaling in non-small cell lung cancer
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-01-16
err0
errOAAI
errDoering, Marietta; Brux, Melanie; Paszkowski-Rogacz, Maciej; Guillem-Gloria, Pedro M.; Buchholz, Frank; Pisabarro, M. Teresa; Theis, Mirko
err分享
err收藏
Quantification of evolved DNA-editing enzymes at scale with DEQSeq
errGENOME BIOLOGY
IF9.4
err2023-11-06
err2
errOAAI
errSchmitt, Lukas Theo; Schneider, Aksana; Posorski, Jonas; Lansing, Felix; Jelicic, Milica; Jain, Manavi; Sayed, Shady; Buchholz, Frank; Sueruen, Duran
err分享
err收藏
TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes
errCELL REPORTS
IF6.9
err2023-10-01
err2
errOAAI
errAich, Meghali; Ansari, Asgar Hussain; Ding, Li; Iesmantavicius, Vytautas; Paul, Deepanjan; Choudhary, Chunaram; Maiti, Souvik; Buchholz, Frank; Chakraborty, Debojyoti
err分享
err收藏
Precise excision of HTLV-1 provirus with a designer-recombinase
errMOLECULAR THERAPY
IF12
err2023-07-01
err6
errOAAI
errRojo-Romanos, Teresa; Karpinski, Janet; Millen, Sebastian; Beschorner, Niklas; Simon, Florian; Paszkowski-Rogacz, Maciej; Lansing, Felix; Schneider, Paul Martin; Sonntag, Jan; Hauber, Joachim; Thoma-Kress, Andrea K.; Buchholz, Frank
err分享
err收藏
Discovery and characterization of novel Cre-type tyrosine site-specific recombinases for advanced genome engineering用于高级基因组工程的新型Cre型酪氨酸位点特异性重组酶的发现和表征
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-05-09
err3
errOAAI
errJelicic, Milica; Schmitt, Lukas Theo; Paszkowski-Rogacz, Maciej; Walder, Angelika; Schubert, Nadja; Hoersten, Jenna; Sueruen, Duran; Buchholz, Frank
err分享
err收藏
Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3AmutNPM1mut AMLs诊断时保留的功能正常和白血病前期hsc与DNMT3AmutNPM1mut AMLs的良好预后相关
errBLOOD ADVANCES
IF7.1
err2023-03-20
err4
errOAAI
errDonato, Elisa; Correia, Nadia; Andresen, Carolin; Karpova, Darja; Wuerth, Roberto; Klein, Corinna; Sohn, Markus; Przybylla, Adriana; Zeisberger, Petra; Rothfelder, Kathrin; Salih, Helmut; Bonig, Halvard; Stasik, Sebastian; Roellig, Christoph; Dolnik, Anna; Bullinger, Lars; Buchholz, Frank; Thiede, Christian; Huebschmann, Daniel; Trumpp, Andreas
err分享
err收藏
Prediction of designer-recombinases for DNA editing with generative deep learning
errNATURE COMMUNICATIONS
IF15.7
err2022-12-27
err20
errOAAI
errSchmitt, Lukas Theo; Paszkowski-Rogacz, Maciej; Jug, Florian; Buchholz, Frank
err分享
err收藏
Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing
errCANCER RESEARCH
IF16.6
err2022-07-08
err17
errOAAI
errSayed, Shady; Sidorova, Olga A.; Hennig, Alexander; Augsburg, Martina; Vesga, Catherine P. Cortes; Abohawya, Moustafa; Schmitt, Lukas T.; Sueruen, Duran; Stange, Daniel E.; Mircetic, Jovan; Buchholz, Frank
err分享
err收藏
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool抗原呈递保护造血干细胞池的完整性
errCELL STEM CELL
IF20.4
err2022-05-01
err34
errOAAI
errHernandez-Malmierca, Pablo; Vonficht, Dominik; Schnell, Alexandra; Uckelmann, Hannah J.; Bollhagen, Alina; Mahmoud, Mohamed A. A.; Landua, Sophie-Luise; van der Salm, Elise; Trautmann, Christine L.; Raffel, Simon; Gruenschlaeger, Florian; Lutz, Raphael; Ghosh, Michael; Renders, Simon; Correia, Nadia; Donato, Elisa; Dixon, Karin O.; Hirche, Christoph; Andresen, Carolin; Robens, Claudia; Werner, Paula S.; Boch, Tobias; Eisel, David; Osen, Wolfram; Pilz, Franziska; Przybylla, Adriana; Klein, Corinna; Buchholz, Frank; Milsom, Michael D.; Essers, Marieke A. G.; Eichmueller, Stefan B.; Hofmann, Wolf-Karsten; Nowak, Daniel; Huebschmann, Daniel; Hundemer, Michael; Thiede, Christian; Bullinger, Lars; Mueller-Tidow, Carsten; Armstrong, Scott A.; Trumpp, Andreas; Kuchroo, Vijay K.; Haas, Simon
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Matthias Mann
H 指数: 250 · 论文数: 1.4K
M
Michael G. Rosenfeld
H 指数: 169 · 论文数: 491
V
Vijay K. Kuchroo
H 指数: 157 · 论文数: 682
N
Norbert Perrimon
H 指数: 154 · 论文数: 868
D
David M. Sabatini
H 指数: 149 · 论文数: 533
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