Timothy A. Brown - Publications, H-index & Citations

Timothy A. Brown

Howard Hughes Medical Institute

35H指数

90论文数

1.0W被引数

收录论文 30

发表时间

A sensitive orange fluorescent calcium ion indicator for imaging neural activity 一种用于神经活动成像的敏感橙色荧光钙离子指示剂

Nature Communications

IF15.7

2026-06-22

OAAI

Abhi Aggarwal; Heather A. Baker; Céline D. Dürst; I-Wen Chen; Pablo de Chambrier; Carrie Stine; Julia Marie Gonzales; Jonathan S. Marvin; Milène Vandal; Torgny Lundberg; Cherie A. Brown-Panton; Kenryo Sakoi; Ronak Patel; Ching-Yao Wang; Frank Visser; Yannick Fouad; Smrithi Sunil; Matthew Wiens; Takuya Terai; Kei Takahashi-Yamashiro; Roger J. Thompson; Timothy A. Brown; Yusuke Nasu; Minh Dang Nguyen; Grant R. J. Gordon; Sarah McFarlane; Kaspar Podgorski; Anthony Holtmaat; Robert E. Campbell; Alexander W. Lohman

Quantification of residual protein from biocatalysts employed in the synthesis of pharmaceutical drug substances using reversed-phase HPLC 采用反相高效液相色谱法对合成药物活性物质所用生物催化剂中的残留蛋白进行定量

Journal of Chromatography A

IF4

2026-05-02

PREAI

Matthew R. Swoyer; Kaitlyn M. Flynn; Timothy A. Brown; Phillip D. Clayman; Emily L. Gill; Andy D. Roberson; Jordan M. Shick; Elizabeth A. Hartnett; James P. Grinias; Justin M. Godinho

iGlucoSnFR2: A genetically encoded fluorescent sensor for measuring intracellular or extracellular glucose in vivo in mouse brain iGlucoSnFR2：一种用于在活体小鼠脑内测量细胞内或细胞外葡萄糖的遗传编码荧光传感器

Science Advances

IF12.5

2025-11-12

PREAI

Jonathan S. Marvin; Philipp Mächler; Chengbo Meng; Tayfun Ates; Ronak H. Patel; Raghabendra Adhikari; Monika A. Makurath; Zaneta Ku; Daniel Feliciano; Deniz Atasoy; Guohong Cui; David Kleinfeld; Timothy A. Brown

DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning DELTA：一种用于全脑测量突触蛋白质周转的方法，揭示了学习期间的区域性可塑性

NATURE NEUROSCIENCE

IF20

2025-03-31

OAAI

Mohar, Boaz; Michel, Gabriela; Wang, Yi-Zhi; Hernandez, Veronica; Grimm, Jonathan B.; Park, Jin-Yong; Patel, Ronak; Clarke, Morgan; Brown, Timothy A.; Bergmann, Cornelius; Gebis, Kamil K.; Wilen, Anika P.; Liu, Bian; Johnson, Richard; Graves, Austin; Tchumatchenko, Tatjana; Savas, Jeffrey N.; Fornasiero, Eugenio F.; Huganir, Richard L.; Tillberg, Paul W.; Lavis, Luke D.; Svoboda, Karel; Spruston, Nelson

iATPSnFR2: A high-dynamic-range fluorescent sensor for monitoring intracellular ATP iATPSnFR2: 一种用于监测细胞内ATP的高动态范围荧光传感器

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-05-15

OAAI

Marvin, Jonathan S.; Kokotos, Alexandros C.; Kumar, Mukesh; Pulido, Camila; Tkachuk, Ariana N.; Yao, Jocelyn Shuxin; Brown, Timothy A.; Ryan, Timothy A.

An engineered biosensor enables dynamic aspartate measurements in living cells 工程生物传感器可在活细胞中进行动态天冬氨酸测量

ELIFE

IF0

2024-02-23

OAAI

Davidsen, Kristian; Marvin, Jonathan S.; Aggarwal, Abhi; Brown, Timothy A.; Sullivan, Lucas B.

Optimized Red-Absorbing Dyes for Imaging and Sensing

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-10-16

OAAI

Grimm, Jonathan B.; Tkachuk, Ariana N.; Patel, Ronak; Hennigan, S. Thomas; Gutu, Alina; Dong, Peng; Gandin, Valentina; Osowski, Anastasia M.; Holland, Katie L.; Liu, Zhe J.; Brown, Timothy A.; Lavis, Luke D.

Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction 线粒体类核的超分辨率荧光成像揭示了它们的空间范围，极限和膜相互作用

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

211

OAAI

Brown, Timothy A.; Tkachuk, Ariana N.; Shtengel, Gleb; Kopek, Benjamin G.; Bogenhagen, Daniel F.; Hess, Harald F.; Clayton, David A.

2,7-Diaminobenzopyrylium Dyes Are Live-Cell Mitochondrial Stains

ACS BIO & MED CHEM AU

IF4.3

2022-02-28

OAAI

Banala, Sambashiva; Tkachuk, Ariana N.; Patel, Ronak; Kumar, Pratik; Brown, Timothy A.; Lavis, Luke D.

A General Method to Improve Fluorophores Using Deuterated Auxochromes

JACS AU

IF8.7

2021-04-23

110

OAAI

Grimm, Jonathan B.; Xie, Liangqi; Casler, Jason C.; Patel, Ronak; Tkachuk, Ariana N.; Falco, Natalie; Choi, Heejun; Lippincott-Schwartz, Jennifer; Brown, Timothy A.; Glick, Benjamin S.; Liu, Zhe; Lavis, Luke D.

Rational Design of Bioavailable Photosensitizers for Manipulation and Imaging of Biological Systems 用于生物系统操作和成像的生物可利用光敏剂的合理设计

CELL CHEMICAL BIOLOGY

IF7.2

2020-08-01

OAAI

Binns, Thomas C.; Ayala, Anthony X.; Grimm, Jonathan B.; Tkachuk, Ariana N.; Castillon, Guillaume A.; Phan, Sebastien; Zhang, Lixia; Brown, Timothy A.; Liu, Zhe; Adams, Stephen R.; Ellisman, Mark H.; Koyama, Minoru; Lavis, Luke D.

A general method to optimize and functionalize red-shifted rhodamine dyes 优化和功能化红移罗丹明染料的通用方法

NATURE METHODS

IF32.1

2020-07-27

176

OAAI

Grimm, Jonathan B.; Tkachuk, Ariana N.; Xie, Liangqi; Choi, Heejun; Mohar, Boaz; Falco, Natalie; Schaefer, Kathy; Patel, Ronak; Zheng, Qinsi; Liu, Zhe; Lippincott-Schwartz, Jennifer; Brown, Timothy A.; Lavis, Luke D.

Improved methods for marking active neuron populations

NATURE COMMUNICATIONS

IF15.7

2018-10-25

108

OAAI

Moeyaert, Benjamien; Holt, Graham; Madangopal, Rajtarun; Perez-Alvarez, Alberto; Fearey, Brenna C.; Trojanowski, Nicholas F.; Ledderose, Julia; Zolnik, Timothy A.; Das, Aniruddha; Patel, Davina; Brown, Timothy A.; Sachdev, Robert N. S.; Eickholt, Britta J.; Larkum, Matthew E.; Turrigiano, Gina G.; Dana, Hod; Gee, Christine E.; Oertner, Thomas G.; Hope, Bruce T.; Schreiter, Eric R.

A general method to fine-tune fluorophores for live-cell and in vivo imaging

NATURE METHODS

IF32.1

2017-09-04

501

OAAI

Grimm, Jonathan B.; Muthusamy, Anand K.; Liang, Yajie; Brown, Timothy A.; Lemon, William C.; Patel, Ronak; Lu, Rongwen; Macklin, John J.; Keller, Philipp J.; Ji, Na; Lavis, Luke D.

General Synthetic Method for Si-Fluoresceins and Si-Rhodamines

ACS CENTRAL SCIENCE

IF10.4

2017-08-09

145

OAAI

Grimm, Jonathan B.; Brown, Timothy A.; Tkachuk, Ariana N.; Lavis, Luke D.

Bright photoactivatable fluorophores for single-molecule imaging 用于单分子成像的明亮光活化荧光团

NATURE METHODS

IF32.1

2016-10-24

321

OAAI

Grimm, Jonathan B.; English, Brian P.; Choi, Heejun; Muthusamy, Anand K.; Mehl, Brian P.; Dong, Peng; Brown, Timothy A.; Lippincott-Schwartz, Jennifer; Liu, Zhe; Lionnet, Timothee; Lavis, Luke D.

Direct Copper(III) Formation from O2 and Copper(I) with Histamine Ligation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-07-28

PREAI

Gary, J. Brannon; Citek, Cooper; Brown, Timothy A.; Zare, Richard N.; Wasinger, Erik C.; Stack, T. Daniel P.

High-density three-dimensional localization microscopy across large volumes 大体积高密度三维定位显微镜

NATURE METHODS

IF32.1

2016-03-07

228

OAAI

Legant, Wesley R.; Shao, Lin; Grimm, Jonathan B.; Brown, Timothy A.; Milkie, Daniel E.; Avants, Brian B.; Lavis, Luke D.; Betzig, Eric

Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

GLIA

IF5.1

2016-01-17

OAAI

Rinholm, Johanne E.; Vervaeke, Koen; Tadross, Michael R.; Tkachuk, Ariana N.; Kopek, Benjamin G.; Brown, Timothy A.; Bergersen, Linda H.; Clayton, David A.

Observation of electrochemically generated nitrenium ions by desorption electrospray ionization mass spectrometry

CHEMICAL SCIENCE

IF7.4

2016-01-01

OAAI

Brown, Timothy A.; Hosseini-Nassab, Niloufar; Chen, Hao; Zare, Richard N.

研究方向