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R

Robert H. Mach

University of Pennsylvania

64H指数
681论文数
1.8W被引数
收录论文 217
发表时间
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A Structure–Activity Relationship Study of Alpha Synuclein PET Radiotracer M503-1619
errMolecules
IF4.6
err2026-08-16
err0
errOAAI
errGui-Long Tian; Chia-Ju Hsieh; Dinahlee Saturnino Guarino; Zsofia Lengyel-Zhand; Wai Kit Chia; Shihong Li; Thomas J. A. Graham; Catherine Hou; Hsiaoju Lee; Anthony J. Young; E. James Petersson; Robert H. Mach
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Machine learning prediction of multiple distinct high-affinity chemotypes for α-synuclein fibrilsΑ-突触核蛋白原纤维的多种不同高亲和力化学型的机器学习预测
errchem. commun.
IF0
err2026-01-17
err0
errOAAI
errXinning Li; Ryann M. Perez; Zhude Tu; Robert H. Mach; Sam Giannakoulias; E. James Petersson
err分享
err收藏
Optical Redox Imaging of Breast Cancer NADH Redox Status Associated with PGC1α Gene Expression乳腺癌NADH氧化还原状态的光学氧化还原成像及其与PGC1α基因表达的关系
errAcademic Radiology
IF3.9
err2025-12-18
err0
errOAAI
errZhenwu Lin; Yu Wen; He N. Xu; Lijun Zhang; Chenbo Zeng; Tony R. Lin; Joanna Floros; Robert Mach; Lin Z. Li
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err收藏
First-in-Human Biodistribution and Dosimetry of [11C]Trimethoprim首次人体生物分布和剂量学研究：[11C]Trimethoprim
errMolecular Imaging and Biology
IF2.5
err2025-11-22
err0
errOAAI
errAnthony J. Young; Robert K. Doot; Joshua K. Cho; Jonathan M. Pham; Alvaro A. Ordonez; Andres F. del Castillo; Tiffany L. Dominguez; Supritha Dugyala; Erin K. Schubert; Hsiaoju Lee; Austin R. Pantel; Robert H. Mach; David A. Mankoff; Mark A. Sellmyer
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Interactions of Neurodegenerative Disease Positron Emission Tomography Imaging Probe Candidates with the C-Terminus of α-Synuclein Fibrils神经退行性疾病正电子发射断层成像探针候选物与α-突触核蛋白纤维C末端之间的相互作用
errChemBioChem
IF2.8
err2025-10-13
err0
errOAAI
errKyle D. Shaffer; Ryann M. Perez; Marshall G. Lougee; Vinayak V. Pagar; Hee Jong Kim; Ho Young Kim; Benjamin A. Garcia; Robert H. Mach; E. James Petersson
err分享
err收藏
Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue利用扩增的路易体痴呆症纤维和放射自显影技术表征放射性配体Tg-1-90B与死后脑组织中α-突触核蛋白纤维的结合作用
errCells 2025, Vol. 14, Page 1477
IF5.2
err2025-09-22
err0
errOAAI
errJennifer Y. O’Shea; Dhruva D. Dhavale; Helen Hwang; Zachary Smith; Thomas J. A. Graham; Robert H. Mach; Paul T. Kotzbauer
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Genetic code expansion and enzymatic modifications as accessible methods for studying site-specific post-translational modifications of alpha-synuclein and tau遗传密码扩展和酶促修饰作为研究α-突触核蛋白和tau蛋白位点特异性翻译后修饰的可行方法
errProtein Science
IF5.2
err2025-09-13
err0
errOAAI
errIbrahim G. Saleh; Marie Shimogawa; Jennifer Ramirez; Bernard Abakah; Yarra Venkatesh; Honey Priya James; Ming-Hao Li; Sarah A. Louie; Marshall G. Lougee; Wai-Kit Chia; Christopher Brue; Richard B. Cooley; Ryan A. Mehl; Tobias Baumgart; Robert H. Mach; David Eliezer; Elizabeth Rhoades; E. James Petersson
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Novel Non-Invasive PET Imaging of Reactive Oxygen Species Using [18 F]ROStrace in Three Proteinopathy-Associated Neurodegenerative Mouse Models使用[18 F]ROStrace的新型非侵入式PET成像技术，对三种蛋白质病相关神经退行性小鼠模型中的活性氧物种进行研究
errAcademic Radiology
IF3.9
err2025-08-14
err0
errOAAI
errYi Zhu; Meagan J. McManus; Robert H. Mach
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Correction: Highlight selection of radiochemistry and radiopharmacy developments by editorial board更正：突出由编辑委员会选定的放射化学和核药房发展内容
errEJNMMI Radiopharmacy and Chemistry
IF3.3
err2025-06-02
err0
errOAAI
errS. Spreckelmeyer; J. Dasilva; C. Decristoforo; R. H. Mach; J. Passchier; G. Carlucci; M. Al Qahtani; A. Duatti; B. T. Cornelissen; J. Engle; A. Denkova; J. J. M. A. Hendrikx; Y. Seimbille; X. Yang; H. Jia; M-R. Zhang; M. Yang; L. Perk; P. Caravan; P. Laverman; Z. Cheng; C. Hoehr; T. Sakr; J. R. Zeevaart
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Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer对一种用于乳腺癌动物模型中PARP抑制剂的简化放射性标记方法的评估
errEJNMMI RESEARCH
IF3
err2025-04-29
err0
errOAAI
errWeng, Chi-Chang; Chiang, Chao-Chih; Chung, Yi-Hsiu; Ho, Yi-Pei; Chang, Yu-Chuan; Hsiao, Ing-Tsung; Mach, Robert H.
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Toward a Small-Molecule Antagonist Radioligand for Positron Emission Tomography Imaging of the Mu Opioid Receptor开发一种用于正电子发射断层扫描成像的小分子拮抗剂放射性配体以靶向μ阿片受体
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2025-03-29
err0
PREAI
errPlakas, K; Hsieh, CJ; Guarino, DS; Hou, C; Chia, WK; Young, A; Schmitz, A; Ho, YP; Weng, CC; Lee, H; Li, SH; Graham, TJA; Mach, RH
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Highlight selection of radiochemistry and radiopharmacy developments by editorial board由编辑委员会突出显示放射化学和放射性药物领域的发展。
errEJNMMI RADIOPHARMACY AND CHEMISTRY
IF3.3
err2025-03-25
err0
errOAAI
errSpreckelmeyer, S.; Dasilva, J.; Decristoforo, C.; Mach, R. H.; Passchier, J.; Carlucci, G.; Qhatani, M. Al; Duatti, A.; Cornelissen, B. T.; Engle, J.; Denkova, A.; Hendrikx, J. J. M. A.; Seimbille, Y.; Yang, X.; Jia, H.; Zhang, M-r.; Yang, M.; Perk, L.; Caravan, P.; Laverman, P.; Cheng, Z.; Hoehr, C.; Sakr, T.; Zeevaart, J. R.
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Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers构效关系及2-(杂芳基-环烷基)-1H-吲哚类化合物作为Tau病正电子发射断层成像放射性示踪剂的评估
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-11
err0
errOAAI
errStehouwer, Jeffrey S.; Huang, Guofeng; Guarino, Dinahlee Saturnino; Debnath, Manik L.; Polu, Ashok; Geib, Steven J.; Lopresti, Brian; Ikonomovic, Milos D.; Mason, Neale; Mach, Robert H.; Mathis, Chester A.
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Monitoring mRNA vaccine antigen expression in vivo using PET/CT使用PET/CT监测mRNA疫苗抗原在体内的表达
errNATURE COMMUNICATIONS
IF15.7
err2025-03-06
err1
errOAAI
errBlizard, Gabrielle S.; Dwivedi, Garima; Pan, Yi-Gen; Hou, Catherine; Etersque, Jean M.; Said, Hooda; Chevrier, Anik; Lavertu, Marc; Ni, Houping; Davis, Benjamin; Tam, Ying; Cao, Quy; Mach, Robert H.; Weissman, Drew; Alameh, Mohamad-Gabriel; Sellmyer, Mark A.
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Noninvasive Detection of Oxidative Stress in a Mouse Model of 4R Tauopathy via Positron Emission Tomography with [18F]ROStrace通过正电子发射断层扫描与[18F]ROStrace检测4Rtau病小鼠模型中的氧化应激
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-02-21
err1
errOAAI
errGallagher, Evan; Li, Shihong; Lee, Hsiaoju; Xu, Hong; Lee, Virginia M. -Y.; Mach, Robert H.; Mcmanus, Meagan J.
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The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease开发一种用于帕金森病中α-突触核蛋白聚集体成像的PET放射性示踪剂
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errTian, Gui-Long; Hsieh, Chia-Ju; Guarino, Dinahlee Saturnino; Graham, Thomas J. A.; Lengyel-Zhand, Zsofia; Schmitz, Alexander; Chia, Wai Kit; Young, Anthony J.; Crosby, John-Grey; Plakas, Konstantinos; Huang, Tianyu; Jiang, Hao; Yu, Yanbo; Hou, Catherine; Lee, Hsiaoju; Petersson, E. James; Giannakoulias, Sam; O'Shea, Jennifer; Kotzbauer, Paul; Tu, Zhude; Mathis, Chester A.; Mach, Robert H.
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[18F]Fluorthanatrace PET in Ovarian Cancer: Comparison with [18F]FDG PET, Lesion Location, Tumor Grade, and Breast Cancer Gene Mutation Status[18F]Fluorthanatrace PET在卵巢癌中的应用：与[18F]FDG PET、病灶位置、肿瘤分级和乳腺癌基因突变状态的比较
errJOURNAL OF NUCLEAR MEDICINE
IF9.1
err2024-12-05
err0
PREAI
errWeeks, Joanna K.; Pantel, Austin R.; Gitto, Sarah B.; Liu, Fang; Schubert, Erin K.; Pryma, Daniel A.; Farwell, Michael D.; Mankoff, David A.; Mach, Robert H.; Simpkins, Fiona; Lin, Lilie L.
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Increased Reactive Oxygen Species using [18F]ROStrace PET and Dihydroethidium Staining in Myocardial Infarction Reperfusion injury使用[18F]ROStrace PET和二氢乙啶染色检测心肌梗死再灌注损伤中的活性氧增加
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errAwad, Marina; Swago, Sophia; Camillo, Chiara; Thompson, Elizabeth; Bhattaru, Abhijit; Moon, Brianna; Ferrari, Giovanni; Castillero, Estibaliz; Gallagher, Evan; Mcmanus, Meagan; Ferrari, Victor; Gorman, Robert; Tschabrunn, Cory; Mach, Robert; Karp, Joel; Bravo, Paco; Witschey, Walter
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Identification and In Vitro and In Vivo Characterization of KAC-50.1 as a Potential α-Synuclein PET RadioligandKAC-50.1作为潜在的 α-突触核蛋白PET放射性配体的鉴定以及体外和体内表征
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-11-11
err0
errOAAI
errGuarino, Dinahlee Saturnino; Azpiazu, Patricia Miranda; Sunnemark, Dan; Elmore, Charles S.; Bergare, Jonas; Artelsmair, Markus; Nordvall, Gunnar; Moren, Anton Forsberg; Jia, Zhisheng; Cortes-Gonzalez, Miguel; Mach, Robert; Wilcox, Kyle C.; Finnema, Sjoerd; Schou, Magnus; Varrone, Andrea
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Automation of simplified two-step radiolabeling via ditosylate synthon for 18F-labeled radiotracers using AllinOne module使用AllinOne模块通过二甲苯磺酸酯合成子对18f标记的放射性示踪剂进行简化的两步放射性标记的自动化
errNUCLEAR MEDICINE AND BIOLOGY
IF3
err2024-11-01
err1
PREAI
errLi, Shihong; Schmitz, Alexander; Lu, Yu-Ting; Pal, Rammyani; Sarkar, Swarbhanu; Sellmyer, Mark A.; Mach, Robert H.; Lee, Hsiaoju
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研究方向

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