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W

William J. Polacheck

University of North Carolina School of Medicine
H指数:29
被引数:5,456

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Targeting hypersialylation in pancreatic cancer microfluidic models reverses its malignant phenotype and enhances CAR-T therapy

靶向胰腺癌微流体模型中的过度唾液酸化可逆转其恶性表型并增强CAR-T疗法

Cell Death & Disease
IF9.6
2026-11-020
OA
Pedro Enrique Guerrero; Jack Zhang-Zhou; Soraya Hernández-Hatibi; Alejandro Martín-Contreras; Patricia Balsas; Júlia López; Maria Del Valle Blazquez-Romero; Laura Miró; María José Gómez-Benito; Diego Sánchez-Martínez; Julián Pardo; William J. Polacheck; Esther Llop; Rosa Peracaula; José Manuel García-Aznar
A novel manganese glycerophosphate vaccine gel elicits broad and durable immunity across an aged and pox virus model

一种新型锰甘油磷酸盐疫苗凝胶在老年和痘病毒模型中诱导广泛且持久的免疫应答

Nanoscale
IF5.1
2026-04-010
OA
Islam, Md Jahirul; Ontiveros-Padilla, Luis; Ehrenzeller, Stephen A.; Middleton, Denzel D.; Roque, John A.; Murphy, Connor T.; Lukesh, Nicole Rose; Hendy, Dylan A.; Pena, Erik S.; Stack, Ryan N.; Polacheck, William J.; Bachelder, Eric M.; Ainslie, Kristy M.
A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine- induced ROCK2/JAM-A complex

淋巴管的3D仿生模型通过细胞因子诱导的ROCK2/jam-a复合物揭示细胞-细胞连接收紧和淋巴水肿

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-10-025
OAAI
Lee, Esak; Chan, Siu-Lung; Lee, Yang; Polacheck, William J.; Kwak, Sukyoung; Wen, Aiyun; Nguyen, Duc- Huy T.; Kutys, Matthew L.; Alimperti, Stella; Kolarzyk, Anna M.; Kwak, Tae Joon; Eyckmans, Jeroen; Bielenberg, Diane R.; Chen, Hong; Chen, Christopher S.
Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation

PIK3CA-driven血管畸形的微生理模型揭示了Rac1和mTORC1/2失调在病变形成中的作用

SCIENCE ADVANCES
IF12.5
2023-02-1710
OAAI
Aw, Wen Yih; Cho, Crescentia; Wang, Hao; Cooper, Anne Hope; Doherty, Elizabeth L.; Rocco, David; Huang, Stephanie A.; Kubik, Sarah; Whitworth, Chloe P.; Armstrong, Ryan; Hickey, Anthony J.; Griffith, Boyce; Kutys, Matthew L.; Blatt, Julie; Polacheck, William J.

研究方向

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Christopher S. Chen
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W
Wen Yih Aw
H 指数:10论文数:60被引数:442
C
Chloe P. Whitworth
H 指数:5论文数:15被引数:114
R
Roger D. Kamm
H 指数:117论文数:769被引数:4.7万
M
Mitesh Rathod
H 指数:9论文数:24被引数:174
S
Stephanie Huang
H 指数:24论文数:74被引数:1,843
E
Elizabeth L. Doherty
H 指数:5论文数:14被引数:116
M
Matthew L. Kutys
H 指数:17论文数:49被引数:1,844
B
Brendon M. Baker
H 指数:42论文数:159被引数:1.0万
R
Rebecca G. Wells
H 指数:69论文数:289被引数:1.6万