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J

Johan H. van Es

University Medical Center

77H指数
197论文数
5.6W被引数
收录论文 86
发表时间
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Fetal reversion from diverse lineages sustains the intestinal stem cell pool and confers stress resilience多种谱系来源的胎儿逆转维持了肠道干细胞库并赋予其抗压能力
errCommunications Biology
IF5.1
err2026-01-13
err0
errOAAI
errSakura Kirino; Fumiya Uefune; Kensuke Miyake; Nobuhiko Ogasawara; Sakurako Kobayashi; Satoshi Watanabe; Yui Hiraguri; Go Ito; Keiichi Akahoshi; Daisuke Ban; Johan H. van Es; Hans Clevers; Mamoru Watanabe; Ryuichi Okamoto; Shiro Yui
err分享
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Human gut M cells resemble dendritic cells and present gluten antigen人肠M细胞类似于树突状细胞并呈递面筋抗原
errNature
IF48.5
err2025-12-10
err0
PREAI
errDaisong Wang; Sangho Lim; Willine J. van de Wetering; Carmen Lopez-Iglesias; Yuu Okura; Yuri Teranishi-Ikawa; Akihiko Mizoroki; Willem Kasper Spoelstra; Talya Dayton; Gijs J. F. van Son; Apollo Pronk; Niels Smakman; Gieneke B. C. Gonera-de Jong; Sebo Withoff; Iris H. Jonkers; Jeroen S. van Zon; Sander J. Tans; Peter J. Peters; Johan H. van Es; Hans Clevers
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A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease患者源性肠器官样细胞系集合揭示了与儿童炎症性肠病遗传驱动因素相关的上皮表型
errINFLAMMATORY BOWEL DISEASES
IF4.3
err2025-11-01
err0
PREAI
errJeshvaghani, Zahra Shojaei; Argmann, Carmen; de Vries, Maaike H.; van Es, Johan H.; Collen, Lauren, V; Kotlarz, Daniel; Sveen, Mia; Comella, Phillip H.; Snapper, Scott B.; Klein, Christoph; Schadt, Eric E.; Clevers, Hans; Mokry, Michal; Kuijk, Ewart; Nieuwenhuis, Edward
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A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels一种整合素激活抗体的单链衍生物能够增强基质胶和胶原蛋白水凝胶中类器官的生长
errNature Biotechnology
IF41.7
err2025-10-28
err0
errOAAI
errWim B. M. de Lau; Joost J. A. P. M. Wijnakker; Gijs J. F. van Son; Daniel Krueger; Daisong Wang; Matthijs S. Abendroth; Robin Schreurs; Claudia Y. Janda; Fenna L. H. van Rijt; Benjamin J. P. Chalopin; Emma Bokobza; Johan H. van Es; Timothy A. Springer; Arnoud Sonnenberg; Hans Clevers
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Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities小鼠舌前上皮类器官建模揭示了区域和细胞特性
errADVANCED SCIENCE
IF14.1
err2025-09-01
err0
errOAAI
errKim, Seok-Young; Verweij, Laurens H. G.; Lin, Lin; van Es, Johan H.; Slack, Jay; Winkel, Chris; Candelli, Tito; Lijnzaad, Philip; Margaritis, Thanasis; Breimer, Gerben E.; Sanders, Karin; van de Wetering, Marc; Clevers, Hans
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Author Correction: HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction作者更正：HDAC1和HDAC2通过破坏β-catenin–TCF相互作用来调节少突胶质细胞分化
errNature Neuroscience
IF20
err2025-07-16
err0
PREAI
errFeng Ye; Ying Chen; ThaoNguyen Hoang; Rusty L. Montgomery; Xian-hui Zhao; Hong Bu; Tom Hu; Makoto M. Taketo; Johan H. van Es; Hans Clevers; Jenny Hsieh; Rhonda Bassel-Duby; Eric N. Olson; Q. Richard Lu
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Human airway submucosal gland organoids to study respiratory inflammation and infection人呼吸道黏膜下腺类器官，用于研究呼吸道炎症和感染
errCell Stem Cell
IF20.4
err2025-06-12
err0
errOAAI
errLin Lin; Carla Pou Casellas; Antonella F.M. Dost; Harry Begthel; Jeroen Korving; Stieneke van den Brink; Talya Dayton; Matthijs F.M. van Oosterhout; Niels Smakman; Lisa Thomann; Volker Thiel; Johan H. van Es; Hans Clevers
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err收藏
A20 controls intestinal homeostasis through cell-specific activities (vol 5, 5103, 2014)A20通过细胞特异性活动调控肠道稳态（vol 5, 5103, 2014）
errNATURE COMMUNICATIONS
IF15.7
err2025-03-31
err0
errOAAI
errVereecke, Lars; Vieira-Silva, Sara; Billiet, Thomas; van Es, Johan H.; Mc Guire, Conor; Slowicka, Karolina; Sze, Mozes; van den Born, Maaike; De Hertogh, Gert; Clevers, Hans; Raes, Jeroen; Rutgeerts, Paul; Vermeire, Severine; Beyaert, Rudi; van Loo, Geert
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Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids通过选择错配修复缺陷型人类结肠类器官中的四个自发致癌突变来重述腺瘤-癌序列
errNATURE CANCER
IF28.5
err2024-11-01
err0
errOAAI
errMizutani, Tomohiro; Boretto, Matteo; Lim, Sangho; Drost, Jarno; Gonzalez, Diego Montiel; Oka, Rurika; Geurts, Maarten H.; Begthel, Harry; Korving, Jeroen; van Es, Johan H.; van Boxtel, Ruben; Clevers, Hans
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A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine人类小肠中单个核受体途径的全面转录组表征
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-10-30
err0
errOAAI
errWillemsen, Sam; Yengej, Fjodor A. Yousef; Puschhof, Jens; Rookmaaker, Maarten B.; Verhaar, Marianne C.; van Es, Johan; Beumer, Joep; Clevers, Hans
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Differences in incidence, nature of symptoms, and duration of long COVID among hospitalised migrant and non-migrant patients in the Netherland: a retrospective cohort study
errEUROPEAN JOURNAL OF PUBLIC HEALTH
IF3.9
err2024-10-28
err0
errOAAI
errChilunga, F.; Appleman, B.; van Vugt, M.; Klaverda, K.; Smeele, P.; van Es, J.; Wiersinga, W. J.; Rostila, M.; Prins, M.; Stronks, K.
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Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7表皮生长因子受体 (EGFR) 是肿瘤抑制因子E3连接酶FBXW7的靶标
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-14
err3
errOAAI
errBorettoa, Matteo; Geurtsa, Maarten H.; Gandhia, Shashank; Mac, Zilian; Staliarovae, Nadzeya; Celottia, Martina; Lima, Sangho; Hea, Gui-Wei; Millena, Rosemary; Driehuisa, Else; Begthela, Harry; Smabersf, Lidwien; Roodhartf, Jeanine; van Esa, Johan; Wu, Wei; Clevers, Hans
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Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome
errMOLECULAR CANCER
IF33.9
err2024-02-21
err3
errOAAI
errBroghammer, Felix; Korovina, Irina; Gouda, Mahesh; Celotti, Martina; van Es, Johan; Lange, Inga; Brunner, Cornelia; Mircetic, Jovan; Coppes, Robert P.; Gires, Olivier; Dahl, Andreas; Seifert, Michael; Cordes, Nils
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Human conjunctiva organoids to study ocular surface homeostasis and disease人类结膜类器官研究眼表稳态和疾病
errCELL STEM CELL
IF20.4
err2024-02-01
err6
errOAAI
errBannier-Helaouet, Marie; Korving, Jeroen; Ma, Zilian; Begthel, Harry; Giladi, Amir; Lamers, Mart M.; van de Wetering, Willine J.; Yawata, Nobuyo; Yawata, Makoto; LaPointe, Vanessa L. S.; Dickman, Mor M.; Kalmann, Rachel; Imhoff, Saskia M.; van Es, Johan H.; Lopez-Iglesias, Carmen; Peters, Peter J.; Haagmans, Bart L.; Wu, Wei; Clevers, Hans
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Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium (vol 36, pg 1793, 2017)Apc和Apc2之间的功能冗余调节组织稳态并防止小鼠乳腺上皮的肿瘤发生 (第36卷，1793页，2017)
errONCOGENE
IF7.3
err2024-01-23
err0
errOAAI
errDaly, C. S.; Shaw, P.; Ordonez, L. D.; Williams, G. T.; Quist, J.; Grigoriadis, A.; Van Es, J. H.; Clevers, H.; Clarke, A. R.; Reed, K. R.
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Urine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation
errBRITISH JOURNAL OF CANCER
IF6.8
err2023-12-15
err6
errOAAI
errViergever, Bastiaan J.; Raats, Danielle A. E.; Geurts, Veerle; Mullenders, Jasper; Jonges, Trudy N.; van der Heijden, Michiel S.; van Es, Johan H.; Kranenburg, Onno; Meijer, Richard P.
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A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury
errNATURE COMMUNICATIONS
IF15.7
err2023-09-05
err6
errOAAI
errCalafiore, Marco; Fu, Ya-Yuan; Vinci, Paola; Arnhold, Viktor; Chang, Winston Y.; Jansen, Suze A.; Egorova, Anastasiya; Takashima, Shuichiro; Kuttiyara, Jason; Ito, Takahiro; Serody, Jonathan; Nakae, Susumu; Turnquist, Heth; Van Es, Johan; Clevers, Hans; Lindemans, Caroline A.; Blazar, Bruce R.; Hanash, Alan M.
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One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids
errNATURE COMMUNICATIONS
IF15.7
err2023-08-17
err16
errOAAI
errGeurts, Maarten H.; Gandhi, Shashank; Boretto, Matteo G.; Akkerman, Ninouk; Derks, Lucca L. M.; van Son, Gijs; Celotti, Martina; Harshuk-Shabso, Sarina; Peci, Flavia; Begthel, Harry; Hendriks, Delilah; Schurmann, Paul; Andersson-Rolf, Amanda; Lopes, Susana M. Chuva de Sousa; van Es, Johan H.; van Boxtel, Ruben; Clevers, Hans
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A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err247
errOAAI
errvan Es, Johan H.; Haegebarth, Andrea; Kujala, Pekka; Itzkovitz, Shalev; Koo, Bon-Kyoung; Boj, Sylvia F.; Korving, Jeroen; van den Born, Maaike; van Oudenaarden, Alexander; Robine, Sylvie; Clevers, Hans
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The function of GORASPs in Golgi apparatus organization in vivo (vol 219, e202004191, 2020)
errJOURNAL OF CELL BIOLOGY
IF6.4
err2020-06-26
err0
errOAAI
errGrond, Rianne; Veenendaal, Tineke; Duran, Juan M.; Raote, Ishier; van Es, Johan H.; Corstjens, Sebastiaan; Delfgou, Laura; El Haddouti, Benaissa; Malhotra, Vivek; Rabouille, Catherine
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研究方向

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合作学者
合作期刊
R
Róbert Langer
H 指数: 262 · 论文数: 2.0K
H
Hans Clevers
H 指数: 236 · 论文数: 1.3K
E
Eric N. Olson
H 指数: 224 · 论文数: 981
G
Gregory J. Hannon
H 指数: 168 · 论文数: 495
T
Timothy A. Springer
H 指数: 165 · 论文数: 734
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