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C

Charles W. Johannes

a*star - institute of sustainability for chemicals, energy & environment (isce2)
H指数:26
被引数:1,951

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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists (vol 15, 489, 2024)

设计规则：具有体内活性的 stapled peptides 及其在 Mdm2/X 抗体中的应用（卷 15，489，2024）

NATURE COMMUNICATIONS
IF15.7
2025-02-130
OA
Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia; Spiegelberg, Diana; Yan, Lin; Juang, Yu-Chi Angela; Ge, Lan; Aronica, Pietro G.; Kaan, Hung Yi Kristal; Lim, Yee Hwee; Peier, Andrea; Sherborne, Brad; Hochman, Jerome; Lin, Songnian; Biswas, Kaustav; Nestor, Marika; Verma, Chandra S.; Lane, David P.; Sawyer, Tomi K.; Garbaccio, Robert; Henry, Brian; Kannan, Srinivasaraghavan; Brown, Christopher J.; Johannes, Charles W.; Partridge, Anthony W.
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
NATURE COMMUNICATIONS
IF15.7
2024-01-128
OAAI
Chandramohan, Arun; Josien, Hubert; Yuen, Tsz Ying; Duggal, Ruchia; Spiegelberg, Diana; Yan, Lin; Juang, Yu-Chi Angela; Ge, Lan; Aronica, Pietro G.; Kaan, Hung Yi Kristal; Lim, Yee Hwee; Peier, Andrea; Sherborne, Brad; Hochman, Jerome; Lin, Songnian; Biswas, Kaustav; Nestor, Marika; Verma, Chandra S.; Lane, David P.; Sawyer, Tomi K.; Garbaccio, Robert; Henry, Brian; Kannan, Srinivasaraghavan; Brown, Christopher J.; Johannes, Charles W.; Partridge, Anthony W.
A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays

一种高通量微流体机械加工平台，可在基于细胞的测定中实现环肽的细胞内递送

BIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
2023-05-131
OAAI
Kasper, Stephen H.; Otten, Stephanie; Squadroni, Brian; Orr-Terry, Cionna; Kuang, Yi; Mussallem, Lily; Ge, Lan; Yan, Lin; Kannan, Srinivasaraghavan; Verma, Chandra S.; Brown, Christopher J.; Johannes, Charles W.; Lane, David P.; Chandramohan, Arun; Partridge, Anthony W.; Roberts, Lee R.; Josien, Hubert; Therien, Alex G.; Hett, Erik C.; Howell, Bonnie J.; Peier, Andrea; Ai, Xi; Cassaday, Jason
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay
ACS CHEMICAL BIOLOGY
IF3.8
2021-02-0434
PREAI
Peier, Andrea; Ge, Lan; Boyer, Nicolas; Frost, John; Duggal, Ruchia; Biswas, Kaustav; Edmondson, Scott; Hermes, Jeffrey D.; Yan, Lin; Zimprich, Chad; Sadruddin, Ahmad; Kaan, Hung Yi Kristal; Chandramohan, Arun; Brown, Christopher J.; Thean, Dawn; Lee, Xue Er; Yuen, Tsz Ying; Ferrer-Gago, Fernando J.; Johannes, Charles W.; Lane, David P.; Sherborne, Brad; Corona, Cesear; Robers, Matthew B.; Sawyer, Tomi K.; Partridge, Anthony W.
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling
CHEMICAL SCIENCE
IF7.4
2021-01-0114
OAAI
Lim, Shuhui; Boyer, Nicolas; Boo, Nicole; Huang, Chunhui; Venkatachalam, Gireedhar; Juang, Yu-Chi Angela; Garrigou, Michael; Kaan, Kristal; Duggal, Ruchia; Peh, Khong Ming; Sadruddin, Ahmad; Gopal, Pooja; Yuen, Tsz Ying; Ng, Simon; Kannan, Srinivasaraghavan; Brown, Christopher J.; Verma, Chandra; Orth, Peter; Peier, Andrea; Ge, Lan; Yu, Xiang; Bhatt, Bhavana; Chen, Feifei; Wang, Erjia; Li, Nianyu Jason; Gonzales, Raymond J.; Stoeck, Alexander; Henry, Brian; Sawyer, Tomi K.; Lane, David; Johannes, Charles W.; Biswas, Kaustav; Partridge, Anthony W.
De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2020-05-0121
OAAI
Ng, Simon; Juang, Yu-Chi; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Ferrer-Gago, Fernando J.; Lee, Xue'Er Cheryl; Liew, Xi; Johannes, Charles W.; Brown, Christopher J.; Kannan, Srinivasaraghavan; Aronica, Pietro G.; Berglund, Nils A.; Verma, Chandra S.; Liu, Lijuan; Stoeck, Alexander; Sawyer, Tomi K.; Partridge, Anthony W.; Lane, David P.
Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability
CHEMICAL SCIENCE
IF7.4
2020-01-0130
OAAI
Kannan, Srinivasaraghavan; Aronica, Pietro G. A.; Ng, Simon; Lian, Dawn Thean Gek; Frosi, Yuri; Chee, Sharon; Jiang, Shimin; Yuen, Tsz Ying; Sadruddin, Ahmad; Kaan, Hung Yi Kristal; Chandramohan, Arun; Wong, Jin Huei; Tan, Yaw Sing; Chang, Zi Wei; Ferrer-Gago, Fernando J.; Arumugam, Prakash; Han, Yi; Chen, Shiying; Renia, Laurent; Brown, Christopher J.; Johannes, Charles W.; Henry, Brian; Lane, David P.; Sawyer, Tomi K.; Verma, Chandra S.; Partridge, Anthony W.
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

在新型装订肽的设计中掺入推定的螺旋断裂氨基酸: 探索生物物理和细胞通透性

MOLECULES
IF4.6
2019-06-2040
OAAI
Partridge, Anthony W.; Kaan, Hung Yi Kristal; Juang, Yu-Chi; Sadruddin, Ahmad; Lim, Shuhui; Brown, Christopher J.; Ng, Simon; Thean, Dawn; Ferrer, Fernando; Johannes, Charles; Yuen, Tsz Ying; Kannan, Srinivasaraghavan; Aronica, Pietro; Tan, Yaw Sing; Pradhan, Mohan R.; Verma, Chandra S.; Hochman, Jerome; Chen, Shiying; Wan, Hui; Ha, Sookhee; Sherborne, Brad; Lane, David P.; Sawyer, Tomi K.
Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2018-06-0151
PREAI
Sawyer, Tomi K.; Partridge, Anthony W.; Kaan, Hung Yi Kristal; Juang, Yu-Chi; Lim, Shuhui; Johannes, Charles; Yuen, Tsz Ying; Verma, Chandra; Kannan, Srinivasaraghavan; Aronica, Pietro; Tan, Yaw Sing; Sherborne, Brad; Ha, Sookhee; Hochman, Jerome; Chen, Shiying; Surdi, Laura; Peier, Andrea; Sauvagnat, Berengere; Dandliker, Peter J.; Brown, Christopher J.; Ng, Simon; Ferrer, Fernando; Lane, David P.

研究方向

暂未获取到该数据
T
Tsz Ying Yuen
H 指数:15论文数:39被引数:571
D
David P. Lane
H 指数:136论文数:960被引数:7.8万
C
Christopher J. Brown
H 指数:32论文数:119被引数:3,796
A
Anthony W. Partridge
H 指数:28论文数:75被引数:3,501
H
Hung Yi Kristal Kaan
H 指数:20论文数:59被引数:1,242
T
Tomi K. Sawyer
H 指数:48论文数:337被引数:1.0万
S
Srinivasaraghavan Kannan
H 指数:31论文数:121被引数:2,880
C
Chandra Verma
H 指数:62论文数:531被引数:1.5万
A
Arun Chandramohan
H 指数:13论文数:28被引数:526
Y
Yee Hwee Lim
H 指数:20论文数:121被引数:1,464