Paulsen, Bruna; Piechota, Sabrina; Barrachina, Ferran; Giovannini, Alexa; Kats, Simone; Potts, Kathryn S.; Rockwell, Graham; Marchante, Maria; Estevez, Samantha L.; Noblett, Alexander D.; Figueroa, Alexandra B.; Aschenberger, Caroline; Kelk, Dawn A.; Forti, Marcy; Marcinyshyn, Shelby; Wiemer, Klaus; Sanchez, Marta; Belchin, Pedro; Lee, Joseph A.; Buyuk, Erkan; Slifkin, Rick E.; Smela, Merrick Pierson; Fortuna, Patrick R. J.; Chatterjee, Pranam; McCulloh, David H.; Copperman, Alan B.; Ordonez-Perez, Daniel; Klein, Joshua U.; Kramme, Christian C.

Programmable protein stabilization with language model-derived peptide guides

基于语言模型衍生的多肽引导的蛋白质可编程稳定化

NATURE COMMUNICATIONS

IF15.7

2025-04-150

Rapid human oogonia-like cell specification via transcription factor-directed differentiation

EMBO REPORTS

IF6.2

2025-01-230

Synergizing sequence and structure representations to predict protein variants

CELL RESEARCH

IF25.9

2024-08-010

Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

从常规刺激周期中使用人类卵母细胞的卵巢支持细胞进行体外成熟，可产生与体内成熟卵母细胞具有改善的核成熟和转录组相似性的卵母细胞

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

IF2.7

2024-05-302

OAAI

Paulsen, Bruna; Piechota, Sabrina; Barrachina, Ferran; Giovannini, Alexa; Kats, Simone; Potts, Kathryn S.; Rockwell, Graham; Marchante, Maria; Estevez, Samantha L.; Noblett, Alexander D.; Figueroa, Alexandra B.; Aschenberger, Caroline; Kelk, Dawn A.; Forti, Marcy; Marcinyshyn, Shelby; Wiemer, Klaus; Sanchez, Marta; Belchin, Pedro; Lee, Joseph A.; Buyuk, Erkan; Slifkin, Rick E.; Smela, Merrick Pierson; Fortuna, Patrick R. J.; Chatterjee, Pranam; Mcculloh, David H.; Copperman, Alan B.; Ordonez-Perez, Daniel; Klein, Joshua U.; Kramme, Christian C.

Design of programmable peptide-guided oncoprotein degraders via generative language models

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-010

PRE

SaLT&PepPr is an interface-predicting language model for designing peptide-guided protein degraders

COMMUNICATIONS BIOLOGY

IF5.1

2023-10-249

OAAI

Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation

HUMAN REPRODUCTION

IF6.1

2023-10-1010

OAAI

Piechota, Sabrina; Marchante, Maria; Giovannini, Alexa; Paulsen, Bruna; Potts, Kathryn S.; Rockwell, Graham; Aschenberger, Caroline; Noblett, Alexander D.; Figueroa, Alexandra B.; Sanchez, Marta; Barrachina, Ferran; Wiemer, Klaus; Guzman, Luis; Belchin, Pedro; Smela, Merrick Pierson; Fortuna, Patrick R. J.; Chatterjee, Pranam; Tran, Nam D.; Kelk, Dawn A.; Forti, Marcy; Marcinyshyn, Shelby; Smith, Trozalla; McCulloh, David H.; Fernandez-Gonzalez, Marta-Julia; Abittan, Baruch; Ortiz, Silvia; Klein, Joshua U.; Klatsky, Peter; Ordonez-Perez, Daniel; Kramme, Christian C.

PAM-flexible genome editing with an engineered chimeric Cas9

NATURE COMMUNICATIONS

IF15.7

2023-10-0411

OAAI

How can the protein design community best support biologists who want to harness AI tools for protein structure prediction and design?

CELL SYSTEMS

IF7.7

2023-08-010

PRE

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

使用pe-tag在体外和体内对prime editor脱靶位点进行全基因组分析