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D

Defang Ouyang

University of Macau

41H指数
183论文数
6.1K被引数
收录论文 114
发表时间
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A RISKmilk framework for predicting drug and chemical exposure in human milk during breastfeeding母乳喂养期间预测人乳中药物和化学品暴露的RISKmilk框架
errPharmacological Research
IF10.5
err2026-09-24
err0
errOAAI
errXinyang Liu; Wei Wang; Ping Xiong; Nannan Wang; Jinying Zhu; Yinyun Qin; Dunjin Chen; Jingsi Chen; Defang Ouyang
err分享
err收藏
Why choose between prediction power and mechanistic insight in QSRR modeling? A case study of artificial membrane chromatography and machine learning为何在QSRR建模中需要在预测能力和机制洞察之间进行选择？——人工膜色谱与机器学习的案例研究
errAnalytica Chimica Acta
IF6
err2026-09-01
err0
PREAI
errNisterenko, Wiktor; Nicman, Julia; Deng, Jiayin; Singh, Yash Raj; Rozycka, Alicja; Greber, Katarzyna Ewa; Szulczyk, Daniel; Nowacki, Michal; Dawidowski, Maciej; Drabczyk, Anna; Jaskowska, Jolanta; Zareba, Przemyslaw; Kulaga, Damian; Staszewski, Marek; Wujec, Monika; Krzeczynski, Piotr; Michalak, Olga; Klejborowska, Greta; Scarpellini, Camilla; Augustyns, Koen; Dernovsek, Jaka; Tomasic, Tihomir; Korabecny, Jan; Fedorowicz, Joanna; Saczewski, Jaroslaw; Sawicki, Wieslaw; Ouyang, Defang; Ciura, Krzesimir
err分享
err收藏
Dissecting corneal drug permeability under experimental variability and drug cold-start challenges via hybrid machine learning通过混合机器学习方法解析实验变异性及药物冷启动挑战下的角膜药物渗透性
errDrug Delivery and Translational Research
IF5.5
err2026-08-05
err0
PREAI
errShuya Xu; Nannan Wang; Yong Tao; Chihua Li; He Song; Defang Ouyang
err分享
err收藏
Machine learning algorithms to predict spray dried protein/ peptide formulations机器学习算法用于预测喷雾干燥蛋白质/肽制剂
errInternational Journal of Pharmaceutics
IF5.2
err2026-06-01
err0
PREAI
errWei, Liping; Deng, Jiayin; Sun, Yang; Yang, Yuchen; Wang, Xin; Gao, Qingxue; Hou, Yanzhu; Sun, Shirui; Fodera, Vito; van de Weert, Marco; Cun, Dongmei; Ouyang, Defang; Yang, Mingshi
err分享
err收藏
Lipid droplets-mediated delivery of curcumin for targeted mitochondrial photodynamic therapy脂滴介导的姜黄素靶向线粒体光动力疗法递送
errinternational journal of pharmaceutics: x
IF0
err2026-05-26
err0
errOAAI
errWen Lin; Shuni Zeng; Qiwei Chen; Zhitao Wang; Defang Ouyang; Yan Ma
err分享
err收藏
Computational insights into drug hygroscopicity by coupling machine learning and molecular simulation通过结合机器学习和分子模拟对药物吸湿性的计算洞察
errDrug Delivery and Translational Research
IF5.5
err2026-04-28
err0
PREAI
errXiaoyi Yin; Nannan Wang; Hao Zhong; Defang Ouyang
err分享
err收藏
DeepDrugDiscovery identifies blood–brain barrier permeable autophagy enhancers for Alzheimer’s diseaseDeepDrugDiscovery鉴定出可透过血脑屏障的自噬增强剂，用于阿尔茨海默病治疗
errNature Biomedical Engineering
IF26.6
err2026-04-24
err0
PREAI
errYu Dong; Xianglu Xiao; Xu-Xu Zhuang; Wenfan Wu; Zi-Ying Wang; Shuang Zhang; Jin-Tao Li; Ke Zhang; Wen-Yu Fu; Jun-Ming Chen; Shi Hang Xiong; Shenglong Deng; Krinos Li; Chao Ma; Wangzhen Jin; Xurui Jin; Qiwei Cai; Han-Ming Shen; Min Li; Huanxing Su; Jian-Bo Wan; Hua Yu; Defang Ouyang; Keqiang Ye; Evandro F. Fang; Chris Soon Heng Tan; Guang Yang; Zhangming Niu; Jia-Hong Lu
err分享
err收藏
Microstructural Insights into Solid Dispersions: A Combined Small-Angle Neutron Scattering and Molecular Dynamics Approach对固体分散体的微观结构见解: 结合小角度中子散射和分子动力学方法
errMolecular Pharmaceutics
IF4.5
err2026-02-07
err0
PREAI
errHaoshi Gao; Yunsen Zhang; Hanqiu Jiang; Chunyong He; Yubin Ke; Haifeng Li; Defang Ouyang
err分享
err收藏
Quality by Computational Design: Harnessing AI to Advance Rational Drug Development计算设计的质量: 利用人工智能推进合理药物开发
errAdvanced Drug Delivery Reviews
IF17.6
err2025-12-20
err0
PREAI
errNannan Wang; Hao Zhong; Ping Xiong; Jinying Zhu; Defang Ouyang
err分享
err收藏
FormulationLAI: A physiology-based machine learning framework for accelerated development of long-acting injectable formulations制剂LAI：一种基于生理学的机器学习框架，用于加速长效注射剂制剂的开发
errJournal of Controlled Release
IF11.5
err2025-11-17
err0
PREAI
errPing Xiong; Jinying Zhu; Hao Zhong; Wei Wang; Nannan Wang; Tianshu Lu; Jiayin Deng; Ruifeng Wang; Yiyang Wu; Yanqing Wang; Defang Ouyang
err分享
err收藏
Overcoming the prediction limitation of small datasets of mRNA lipid nanoparticles: Leveraging the power of language models and multi-task learning克服mRNA脂质纳米颗粒小数据集的预测限制：利用语言模型和多任务学习的力量
errActa Pharmaceutica Sinica B
IF14.6
err2025-11-01
err0
errOAAI
errYiyang Wu; Yuanjia Hu; Jianxin Wang; Defang Ouyang
err分享
err收藏
Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets揭示干扰素基因对三阴性乳腺癌免疫微环境的影响：识别治疗靶点
errFrontiers in Bioinformatics
IF3.9
err2025-10-08
err0
errOAAI
errYing Liu†; Jiayi Cai†; Aamir Fahira†; Kai Zhuang; Jiaojiao Wang; Zhi Zhang; Lin Yan; Yong Liu; Defang Ouyang; Zunnan Huang
err分享
err收藏
Artificial intelligence for drug delivery: Yesterday, today and tomorrow药物递送的人工智能：昨日、今日与明日
errActa Pharmaceutica Sinica B
IF14.6
err2025-09-17
err0
errOAAI
errYiyang Wu; Nannan Wang; Ping Xiong; Ruifeng Wang; Jiayin Deng; Defang Ouyang
err分享
err收藏
Integrating artificial intelligence and physiologically based pharmacokinetic modeling to predict in vitro and in vivo fate of amorphous solid dispersions将人工智能和生理学基础药代动力学模型相结合，以预测无定形固体分散体的体外和体内命运
errJournal of Controlled Release
IF11.5
err2025-08-16
err0
PREAI
errJinying Zhu; Ping Xiong; Wei Wang; Tianshu Lu; Defang Ouyang
err分享
err收藏
Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap-DNAs and Alleviating Pulmonary Fibrosis吸入性人工多聚体核酸酶降解中性粒细胞胞外陷阱-DNAs并缓解肺纤维化
errAdvanced Science
IF14.1
err2025-06-20
err0
errOAAI
errYibo Du; Chenxu Zhu; Ruifeng Wang; Shi Chen; Chuang Li; Defang OuYang; Lixin Liu; Yongming Chen
err分享
err收藏
Determining the Optimal Dosing of Methyldopa in Pregnancy-Induced Hypertension Using PBPK-PD Modeling利用PBPK-PD模型确定甲基多巴在妊娠期高血压中的最佳剂量
errClinical Pharmacokinetics
IF4
err2025-06-14
err0
PREAI
errXinyang Liu; Wei Wang; Jinying Zhu; Jingsi Chen; Xiaoyi Wang; Dunjin Chen; Defang Ouyang
err分享
err收藏
Machine learning-driven insights into retention mechanism in IAM chromatography of anticancer sulfonamides: Implications for biological efficacy机器学习驱动的抗肿瘤磺酰胺在IAM色谱中保留机制的见解：对生物效力的启示
errJOURNAL OF CHROMATOGRAPHY A
IF4
err2025-06-01
err0
PREAI
errNisterenko, Wiktor; Zolnowska, Beata; Deng, Jiayin; Zgoda, Dominika; Rozycka, Alicja; Greber, Katarzyna Ewa; Pogorzelska, Aneta; Szafranski, Krzysztof; Bulakowska, Anita; Tomorowicz, Lukasz; Kawiak, Anna; Sawicki, Wieslaw; Ouyang, Defang; Slawinski, Jaroslaw; Ciura, Krzesimir
err分享
err收藏
An Integrated AI-PBPK Platform for Predicting Drug In Vivo Fate and Tissue Distribution in Human and Inter-Species Extrapolation一个集成的AI-PBPK平台，用于预测药物在人体内的命运和组织分布以及种间外推
errClinical Pharmacology & Therapeutics
IF5.5
err2025-05-26
err0
PREAI
errWei Wang; Nannan Wang; Yiyang Wu; Zhuyifan Ye; Liang Zhao; Xianfeng Chen; Defang Ouyang
err分享
err收藏
Application of in-silico approaches in subunit vaccines: Overcoming the challenges of antigen and adjuvant development基于计算机方法的亚单位疫苗应用：克服抗原和佐剂开发的挑战
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2025-05-01
err0
PREAI
errTang, Xue; Deng, Jiayin; He, Chunting; Xu, Yanhua; Bai, Shuting; Guo, Zhaofei; Du, Guangsheng; Ouyang, Defang
err分享
err收藏
Enhanced antibody-mediated cellular cytotoxicity of germline-like anti-HER2 antibodies through a point mutation in complementarity-determining regions
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-04-01
err0
errOAAI
errZhou, Guangyu; Zhang, Yunsen; Gu, Yuheng; Cao, Bihui; Fan, Xin; Yu, Di; Fu, Shengyu; Liu, Manting; Assaraf, Yehuda G.; Li, Yaping; Ouyang, Defang; Zhao, Qi
err分享
err收藏

研究方向

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合作学者
合作期刊
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