Marc J. Lajoie - Publications, H-index & Citations

Marc J. Lajoie

Harvard University

21H指数

50论文数

3.5K被引数

收录论文 17

发表时间

In vitro modeling of antigen-driven exhaustion in human CAR T cells

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Steele, Maria; Tan, Tina; Yokoyama, Jason; Wang, Allan; Crowl, Ty; Hammer, Jared; Chen, Jerry; Haworth, Kevin; Moffett, Howell; Foster, Aaron; Lajoie, Marc; Boyken, Scott; Amin, Rupesh

Development of tumor-restricted IL-12 with antigen-dependent expression and localized IL-12 activity

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Huang, Szu-Han; Davenport, Thaddeus M.; Moffett, Howell F.; Weitzner, Brian D.; Cassereau, Luke; Baker, Laura E.; Hammerson, Bradley; Zhuang, Summer; Saechao, Christine; Song, Lisa; Mimms, Jade; Chian, David; Sims, Candace; Hiraragi, Hajime; Lajoie, Marc J.; Boyken, Scott E.; Boldajipour, Bijan

OPB-101: An optimized mesothelin-specific CAR T cell product expressing CD8-targeted IL-2/15 and engineered to resist T cell exhaustion

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Amin, Rupesh; Moffett, Howell; Haworth, Kevin; Chen, Jerry; Yokoyama, Jason; Wang, Allan; Tait, Leah; Steele, Maria; Crowl, John; Davenport, Thaddeus; DeSautelle, Joseph; Hammer, Jared; Obenza, Willimark; Montoya, Vanessa; Kirkpatrick, Robin; Baker, Laura; Tan, Tina; Shirley, Kristie; Hammerson, Bradley; Langan, Robert; Clausen, David; Sample, Paul; Weitzner, Brian; Yuan, Shujun; Lajoie, Marc; Boyken, Scott; Foster, Aaron

In vivo selection of synthetic nucleocapsids for tissue targeting

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-11-08

OAAI

Olshefsky, Audrey; Benasutti, Halli; Sylvestre, Meilyn; Butterfield, Gabriel L.; Rocklin, Gabriel J.; Richardson, Christian; Hicks, Derrick R.; Lajoie, Marc J.; Song, Kefan; Leaf, Elizabeth; Treichel, Catherine; Decarreau, Justin; Ke, Sharon; Kher, Gargi; Carter, Lauren; Chamberlain, Jeffrey S.; Baker, David; King, Neil P.; Pun, Suzie H.

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy

NATURE BIOTECHNOLOGY

IF41.7

2022-10-31

OAAI

Quijano-Rubio, Alfredo; Bhuiyan, Aladdin M.; Yang, Huilin; Leung, Isabel; Bello, Elisa; Ali, Lestat R.; Zhangxu, Kevin; Perkins, Jilliane; Chun, Jung-Ho; Wang, Wentao; Lajoie, Marc J.; Ravichandran, Rashmi; Kuo, Yun-Huai; Dougan, Stephanie K.; Riddell, Stanley R.; Spangler, Jamie B.; Dougan, Michael; Silva, Daniel-Adriano; Baker, David

Characterizing the portability of phage-encoded homologous recombination proteins

NATURE CHEMICAL BIOLOGY

IF13.7

2021-01-18

OAAI

Filsinger, Gabriel T.; Wannier, Timothy M.; Pedersen, Felix B.; Lutz, Isaac D.; Zhang, Julie; Stork, Devon A.; Debnath, Anik; Gozzi, Kevin; Kuchwara, Helene; Volf, Verena; Wang, Stan; Rios, Xavier; Gregg, Christopher J.; Lajoie, Marc J.; Shipman, Seth L.; Aach, John; Laub, Michael T.; Church, George M.

Conditional Recruitment to a DNA-Bound CRISPR-Cas Complex Using a Colocalization-Dependent Protein Switch 使用共定位依赖性蛋白质开关有条件地招募到DNA结合的crispr-cas复合物

ACS SYNTHETIC BIOLOGY

IF3.9

2020-08-20

OAAI

Kirkpatrick, Robin L.; Lewis, Kieran; Langan, Robert A.; Lajoie, Marc J.; Boyken, Scott E.; Eakman, Madeleine; Baker, David; Zalatan, Jesse G.

Conditionally active de novo IL-2 cytokine mimetics for targeted immunotherapy: de novo split technology

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Quijano-Rubio, Alfredo; Ali, Lestat R.; Bhuiyan, Md A.; Lajoie, Marc J.; Dougan, Michael; Baker, David; Silva, Daniel-Adriano

Improved bacterial recombineering by parallelized protein discovery 通过平行蛋白质发现改进细菌重组工程

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-05-28

OAAI

Wannier, Timothy M.; Nyerges, Akos; Kuchwara, Helene M.; Czikkely, Marton; Balogh, David; Filsinger, Gabriel T.; Borders, Nathaniel C.; Gregg, Christopher J.; Lajoie, Marc J.; Rios, Xavier; Pal, Csaba; Church, George M.

Rewriting the Genetic Code

ANNUAL REVIEW OF MICROBIOLOGY

IF0

2017-09-08

132

OAAI

Mukai, Takahito; Lajoie, Marc J.; Englert, Markus; Soll, Dieter

Optimizing complex phenotypes through model-guided multiplex genome engineering

GENOME BIOLOGY

IF9.4

2017-05-25

OAAI

Kuznetsov, Gleb; Goodman, Daniel B.; Filsinger, Gabriel T.; Landon, Matthieu; Rohland, Nadin; Aach, John; Lajoie, Marc J.; Church, George M.

Millstone: software for multiplex microbial genome analysis and engineering

GENOME BIOLOGY

IF9.4

2017-05-25

OAAI

Goodman, Daniel B.; Kuznetsov, Gleb; Lajoie, Marc J.; Ahern, Brian W.; Napolitano, Michael G.; Chen, Kevin Y.; Chen, Changping; Church, George M.

An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes

NATURE CHEMICAL BIOLOGY

IF13.7

2017-02-13

126

PREAI

Italia, James S.; Addy, Partha Sarathi; Wrobel, Chester J. J.; Crawford, Lisa A.; Lajoie, Marc J.; Zheng, Yunan; Chatterjee, Abhishek

Multiplex pairwise assembly of array-derived DNA oligonucleotides

NUCLEIC ACIDS RESEARCH

IF13.1

2015-11-08

OAAI

Klein, Jason C.; Lajoie, Marc J.; Schwartz, Jerrod J.; Strauch, Eva-Maria; Nelson, Jorgen; Baker, David; Shendure, Jay

Rational optimization of tolC as a powerful dual selectable marker for genome engineering

NUCLEIC ACIDS RESEARCH

IF13.1

2014-01-22

OAAI

Gregg, Christopher J.; Lajoie, Marc J.; Napolitano, Michael G.; Mosberg, Joshua A.; Goodman, Daniel B.; Aach, John; Isaacs, Farren J.; Church, George M.

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

NUCLEIC ACIDS RESEARCH

IF13.1

2012-05-24

OAAI

Carr, Peter A.; Wang, Harris H.; Sterling, Bram; Isaacs, Farren J.; Lajoie, Marc J.; Xu, George; Church, George M.; Jacobson, Joseph M.

Lambda Red Recombineering in Escherichia coli Occurs Through a Fully Single-Stranded Intermediate

GENETICS

IF5.1

2010-11-01

188

OAAI

Mosberg, J. A.; Lajoie, M. J.; Church, G. M.

研究方向