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Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export ATP结合盒转运蛋白ABCC1的结构揭示了环二核苷酸cGAMP外排的分子基础 Shinde, Omkar; Boyer, Joshua A.; Cambier, Stephanie; Vanportfliet, Jordyn J.; Sui, Xuewu; Yadav, Gaya P.; Viverette, Elizabeth G.; Borgnia, Mario J.; West, A. Phillip; Zhang, Qi; Stetson, Daniel B.; Li, Pingwei 分享 收藏
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Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease Huang, Xiangyu; Zhao, Zhenchao; Zhu, Cheng; Chai, Lvye; Yan, Ya; Yuan, Ye; Wu, Lei; Li, Minjie; Jiang, Xiaohan; Wang, Haiwei; Liu, Zheng; Li, Pingwei; Li, Xin 分享 收藏
Structural Evaluations of a Selective Human STINGA230 Agonist and Its Use in Macrophage Immunotherapies 选择性人STINGA230激动剂的结构评估及其在巨噬细胞免疫疗法中的用途 Tang, Zhichao; Zhao, Junxing; Li, Ying; Tomer, Shallu; Selvaraju, Manikandan; Tien, Nicholas; Sun, Diyun; Johnson, David K.; Zhen, Anjie; Li, Pingwei; Wang, Jingxin 分享 收藏
Species-specific cleavage of cGAS by picornavirus protease 3C disrupts mitochondria DNA-mediated immune sensing Yan, Ya; Wu, Lei; Yuan, Ye; Wang, Haiwei; Yin, Hongyan; Li, Minjie; Chai, Lvye; Liang, Ruiying; Liu, Yanjie; Zhao, Dongming; Xing, Junji; Li, Pingwei; Li, Xin 分享 收藏
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease Yang, Kai S.; Blankenship, Lauren R.; Kuo, Syuan-Ting Alex; Sheng, Yan J.; Li, Pingwei; Fierke, Carol A.; Russell, David H.; Yan, Xin; Xu, Shiqing; Liu, Wenshe Ray 分享 收藏
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals 基于boceprevir的主要蛋白酶抑制剂作为SARS-CoV-2抗病毒药物的系统探索 Alugubelli, Yugendar R.; Geng, Zhi Zachary; Yang, Kai S.; Shaabani, Namir; Khatua, Kaustav; Ma, Xinyu R.; Vatansever, Erol C.; Cho, Chia-Chuan; Ma, Yuying; Xiao, Jing; Blankenship, Lauren R.; Yu, Ge; Sankaran, Banumathi; Li, Pingwei; Allen, Robert; Ji, Henry; Xu, Shiqing; Liu, Wenshe Ray 分享 收藏
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals 基于醛的三肽基主要蛋白酶抑制剂作为SARS-CoV-2抗病毒药物的多管齐下评估 Ma, Yuying; Yang, Kai S.; Geng, Zhi Zachary; Alugubelli, Yugendar R.; Shaabani, Namir; Vatansever, Erol C.; Ma, Xinyu R.; Cho, Chia-Chuan; Khatua, Kaustav; Xiao, Jing; Blankenship, Lauren R.; Yu, Ge; Sankaran, Banumathi; Li, Pingwei; Allen, Robert; Ji, Henry; Xu, Shiqing; Liu, Wenshe Ray 分享 收藏
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A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors** 多种高效SARS-CoV-2主要蛋白酶抑制剂的快速途径 ** Yang, Kai S.; Ma, Xinyu R.; Ma, Yuying; Alugubelli, Yugendar R.; Scott, Danielle A.; Vatansever, Erol C.; Drelich, Aleksandra K.; Sankaran, Banumathi; Geng, Zhi Z.; Blankenship, Lauren R.; Ward, Hannah E.; Sheng, Yan J.; Hsu, Jason C.; Kratch, Kaci C.; Zhao, Baoyu; Hayatshahi, Hamed S.; Liu, Jin; Li, Pingwei; Fierke, Carol A.; Tseng, Chien-Te K.; Xu, Shiqing; Liu, Wenshe Ray 分享 收藏
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The malectin-like receptor-like kinase LETUM1 modulates NLR protein SUMM2 activation via MEKK2 scaffolding Liu, Jun; Huang, Yanyan; Kong, Liang; Yu, Xiao; Feng, Baomin; Liu, Derui; Zhao, Baoyu; Mendes, Giselle C.; Yuan, Peiguo; Ge, Dongdong; Wang, Wen-Ming; Fontes, Elizabeth P. B.; Li, Pingwei; Shan, Libo; He, Ping 分享 收藏
TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection Hoffpauir, Caitlyn T.; Bell, Samantha L.; West, Kelsi O.; Jing, Tao; Wagner, Allison R.; Torres-Odio, Sylvia; Cox, Jeffery S.; West, A. Phillip; Li, Pingwei; Patrick, Kristin L.; Watson, Robert O. 分享 收藏
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The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming Zhou, Xiaofei; Yu, Jiayi; Cheng, Xuhong; Zhao, Baoyu; Manyam, Ganiraju C.; Zhang, Li; Schluns, Kimberly; Li, Pingwei; Wang, Jing; Sun, Shao-Cong 分享 收藏
Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon Li, Xin; Deng, Meng; Petrucelli, Alex S.; Zhu, Cheng; Mo, Jinyao; Zhang, Lu; Tam, Jason W.; Ariel, Pablo; Zhao, Baoyu; Zhang, Song; Ke, Hengming; Li, Pingwei; Dokholyan, Nikolay, V; Duncan, Joseph A.; Ting, Jenny P-Y 分享 收藏
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