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Novel Multikinase Clk Inhibitor BH-30236 Targets Hematological Malignancies through Alternative Splicing Regulation 新型多激酶Clk抑制剂BH-30236通过选择性剪接调控靶向血液系统恶性肿瘤 Ling, Nancy; Sims, Gregory; Jiang, Ping; Deng, Wei; Zhai, Dayong; Li, Danan; Wang, Zhenping; Hu, Yue; Wang, Eric; Graber, Armin; Cui, J. Jean 分享 收藏
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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition Chaudhry, Sana; Beckedorff, Felipe; Jasdanwala, Shaista Shabbir; Totiger, Tulasigeri M.; Affer, Maurizio; Lawal, Abimbola Eunice; Montoya, Skye; Tamiro, Francesco; Tonini, Olivia; Chirino, Alexandra; Adams, Andrew; Sondhi, Anya K.; Noudali, Stephen; Cornista, Alyssa Mauri; Nicholls, Miah; Afaghani, Jumana; Robayo, Paola; Bilbao, Daniel; Nimer, Stephen D.; Rodriguez, Jose Antonio; Bhatt, Shruti; Wang, Eric; Taylor, Justin 分享 收藏
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies Benbarche, Salima; Pineda, Jose Mario Bello; Galvis, Laura Baquero; Biswas, Jeetayu; Liu, Bo; Wang, Eric; Zhang, Qian; Hogg, Simon J.; Lyttle, Kadeen; Dahi, Ariana; Lewis, Alexander M.; Saechi, Martina; Rahman, Jahan; Fox, Nina; Ai, Yuxi; Mehta, Sanjoy; Garippa, Ralph; Ortiz-Pacheco, Juliana; Li, Zhuoning; Monetti, Mara; Stanley, Robert F.; Doulatov, Sergei; Bradley, Robert K.; Abdel-Wahab, Omar 分享 收藏
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Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia Knorr, Katherine; Rahman, Jahan; Erickson, Caroline; Wang, Eric; Monetti, Mara; Li, Zhuoning; Ortiz-Pacheco, Juliana; Jones, Andrew; Lu, Sydney X.; Stanley, Robert F.; Baez, Maria; Fox, Nina; Castro, Cynthia; Marino, Alessandra E.; Jiang, Caroline; Penson, Alex; Hogg, Simon J.; Mi, Xiaoli; Nakajima, Hideaki; Kunimoto, Hiroyoshi; Nishimura, Koutarou; Inoue, Daichi; Greenbaum, Benjamin; Knorr, David; Ravetch, Jeffrey; Abdel-Wahab, Omar 分享 收藏
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity Thomas, James D.; Lu, Sydney X.; De Neef, Emma; Sabio, Erich; Rousseau, Benoit; Gigoux, Mathieu; Knorr, David A.; Greenbaum, Benjamin; Elhanati, Yuval; Hogg, Simon J.; Chow, Andrew; Ghosh, Arnab; Xie, Abigail; Zamarin, Dmitriy; Cui, Daniel; Erickson, Caroline; Singer, Michael; Cho, Hana; Wang, Eric; Lu, Bin; Durham, Benjamin H.; Shah, Harshal; Chowell, Diego; Gabel, Austin M.; Shen, Yudao; Liu, Jing; Jin, Jian; Rhodes, Matthew C.; Taylor, Richard E.; Molina, Henrik; Wolchok, Jedd D.; Merghoub, Taha; Diaz, Luis A., Jr.; Abdel-Wahab, Omar; Bradley, Robert K. 分享 收藏
Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening Tan, Jimin; Shenker-Tauris, Nina; Rodriguez-Hernaez, Javier; Wang, Eric; Sakellaropoulos, Theodore; Boccalatte, Francesco; Thandapani, Palaniraja; Skok, Jane; Aifantis, Iannis; Fenyo, David; Xia, Bo; Tsirigos, Aristotelis 分享 收藏
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NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia NUDT21通过替代mRNA聚腺苷酸化限制b细胞急性淋巴细胞白血病的CD19水平 Witkowski, Matthew T.; Lee, Soobeom; Wang, Eric; Lee, Anna K.; Talbot, Alexis; Ma, Chao; Tsopoulidis, Nikolaos; Brumbaugh, Justin; Zhao, Yaqi; Roberts, Kathryn G.; Hogg, Simon J.; Nomikou, Sofia; Ghebrechristos, Yohana E.; Thandapani, Palaniraja; Mullighan, Charles G.; Hochedlinger, Konrad; Chen, Weiqiang; Abdel-Wahab, Omar; Eyquem, Justin; Aifantis, Iannis 分享 收藏
The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation 炎症诱导的肿瘤可塑性在髓系转化中的影响 Yeaton, Anna; Cayanan, Geraldine; Loghavi, Sanam; Dolgalev, Igor; Leddin, Emmett M.; Loo, Christian E.; Torabifard, Hedieh; Nicolet, Deedra; Wang, Jingjing; Corrigan, Kate; Paraskevopoulou, Varvara; Starczynowski, Daniel T.; Wang, Eric; Abdel-Wahab, Omar; Viny, Aaron D.; Stone, Richard M.; Byrd, John C.; Guryanova, Olga A.; Kohli, Rahul M.; Cisneros, G. Andres; Tsirigos, Aristotelis; Eisfeld, Ann-Kathrin; Aifantis, Iannis; Guillamot, Maria 分享 收藏
Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation Chen, Sisi; Vedula, Rahul S.; Cuevas-Navarro, Antonio; Lu, Bin; Hogg, Simon J.; Wang, Eric; Benbarche, Salima; Knorr, Katherine; Kim, Won Jun; Stanley, Robert F.; Cho, Hana; Erickson, Caroline; Singer, Michael; Cui, Dan; Tittley, Steven; Durham, Benjamin H.; Pavletich, Tatiana S.; Fiala, Elise; Walsh, Michael F.; Inoue, Daichi; Monette, Sebastien; Taylor, Justin; Rosen, Neal; McCormick, Frank; Lindsley, R. Coleman; Castel, Pau; Abdel-Wahab, Omar 分享 收藏
Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors Wang, Eric; Mi, Xiaoli; Thompson, Meghan C.; Montoya, Skye; Notti, Ryan Q.; Afaghani, Jumana; Durham, Benjamin H.; Penson, Alex; Witkowski, Matthew T.; Lu, Sydney X.; Bourcier, Jessie; Hogg, Simon J.; Erickson, Caroline; Cui, Dan; Cho, Hana; Singer, Michael; Totiger, Tulasigeri M.; Chaudhry, Sana; Geyer, Mark; Alencar, Alvaro; Linley, Adam J.; Palomba, M. Lia; Coombs, Catherine C.; Park, Jae H.; Zelenetz, Andrew; Roeker, Lindsey; Rosendahl, Mary; Tsai, Donald E.; Ebata, Kevin; Brandhuber, Barbara; Hyman, David M.; Aifantis, Iannis; Mato, Anthony; Taylor, Justin; Abdel-Wahab, Omar 分享 收藏
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