Jared E. Toettcher - Publications, H-index & Citations

Jared E. Toettcher

princeton university

37H指数

116论文数

7.3K被引数

收录论文 54

发表时间

Design and optimization of a kinase-controlled allosteric switch 激酶调控别构开关的设计与优化

Nature Methods

IF32.1

2026-07-21

OAAI

Qinhao Cao; Jared E. Toettcher

An optogenetic smart microscopy platform reveals signaling dynamics-dependent control over collective cell migration 光遗传学智能显微平台揭示信号动力学依赖的集体细胞迁移控制

Cell Systems

IF7.7

2026-07-16

OAAI

Harrison R. Oatman; Beena C. Lad; Long Nguyen; Justin H. Gubbens; Jared E. Toettcher

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration CD44限制EGFR的移动性以极化驱动囊泡基迁移的细胞骨架信号模块

Nature Cell Biology

IF19.1

2026-07-06

OAAI

Ankita Jha; Ankit Chandra; Payam E. Farahani; Jared E. Toettcher; Ana M. Pasapera; Jason M. Haugh; Clare M. Waterman

Multimodal control of Cas13d activity through domain insertion at an allosteric hotspot 通过在别构热点处插入结构域对Cas13d活性进行多模态调控

Nature Communications

IF15.7

2026-06-03

OAAI

Liyuan Zhu; Long T. Nguyen; Alexandra G. Bell; Tom Krebel; Kara M. Gillmann; Qinhao Cao; Harrison Oatman; Jack Hariri; Andreas Möglich; Cameron Myhrvold; Jared E. Toettcher

Lights up on the embryonic dance: tools and applications of optogenetics in developmental biology 照亮胚胎发育之舞：光遗传学在发育生物学中的工具与应用

GENES & DEVELOPMENT

IF7.7

2026-05-01

PREAI

Gao, Yang; Ho, Emily K.; Toettcher, Jared E.

Efficient genome editing with chimeric oligonucleotide-directed editing 利用嵌合寡核苷酸定向编辑进行高效基因组编辑

Nature Communications

IF15.7

2026-04-13

OAAI

Long T. Nguyen; Noah R. Rakestraw; Brianna L. M. Pizzano; Rajan Iyyappan; Cullen B. Young; Yujia Huang; Kate T. Beerensson; Anne Fang; Sydney G. Antal; Katerina V. Anamisis; Coleen M. D. Peggs; Jun Yan; Yangwode Jing; Jordan G. Lewis; Rebecca D. Burdine; Britt Adamson; Zongliang Jiang; Jared E. Toettcher; Cameron Myhrvold; Piyush K. Jain

Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation 活体成像内源性转录因子动力学揭示外胚层和原始内胚层命运分离的机制

Current Biology

IF7.5

2025-07-31

OAAI

Rebecca P. Kim-Yip; David Denberg; Denis F. Faerberg; Hayden Nunley; Isabella Leite; Madeleine Chalifoux; Bradley Joyce; Jared Toettcher; Bin Gu; Eszter Posfai

Large-scale control over collective cell migration using light-activated epidermal growth factor receptors 利用光激活表皮生长因子受体对集体细胞迁移进行大规模控制

CELL SYSTEMS

IF7.7

2025-03-01

PREAI

Suh, Kevin; Thornton, Richard H.; Nguyen, Long; Farahani, Payam E.; Cohen, Daniel J.; Toettcher, Jared E.

Engineered chimeric receptors for dissecting interferon signaling

JOURNAL OF VIROLOGY

IF3.8

2024-10-22

PREAI

Lin, Aaron E.; Mesev, Emily V.; Toettcher, Jared E.; Ploss, Alexander

Recording morphogen signals reveals mechanisms underlying gastruloid symmetry breaking 记录形态发生信号揭示了类胃对称性破坏的机制

NATURE CELL BIOLOGY

IF19.1

2024-10-02

PREAI

McNamara, Harold M.; Solley, Sabrina C.; Adamson, Britt; Chan, Michelle M.; Toettcher, Jared E.

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

NATURE COMMUNICATIONS

IF15.7

2024-08-07

OAAI

Brumbaugh-Reed, Ellen H.; Gao, Yang; Aoki, Kazuhiro; Toettcher, Jared E.

Efficient prime editing in two-cell mouse embryos using PEmbryo

NATURE BIOTECHNOLOGY

IF41.7

2024-02-06

OAAI

Kim-Yip, Rebecca P.; Mcnulty, Ryan; Joyce, Bradley; Mollica, Antonio; Chen, Peter J.; Ravisankar, Purnima; Law, Benjamin K.; Liu, David R.; Toettcher, Jared E.; Ivakine, Evgueni A.; Posfai, Eszter; Adamson, Britt

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors

SCIENCE SIGNALING

IF6.6

2023-10-10

OAAI

Mesev, Emily V.; Lin, Aaron E.; Guare, Emma G.; Heller, Brigitte L.; Douam, Florian; Adamson, Britt; Toettcher, Jared E.; Ploss, Alexander

Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the Drosophila

DEVELOPMENT

IF3.6

2023-09-01

OAAI

Ho, Emily K.; Oatman, Harrison R.; Mcfann, Sarah E.; Yang, Liu; Johnson, Heath E.; Shvartsman, Stanislav Y.; Toettcher, Jared E.

Light-switchable transcription factors obtained by direct screening in mammalian cells

NATURE COMMUNICATIONS

IF15.7

2023-06-02

OAAI

Zhu, Liyuan; McNamara, Harold M.; Toettcher, Jared E.

pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

ELIFE

IF0

2023-05-22

OAAI

Farahani, Payam E.; Yang, Xiaoyu; Mesev, Emily, V; Fomby, Kaylan A.; Brumbaugh-Reed, Ellen H.; Bashor, Caleb J.; Nelson, Celeste M.; Toettcher, Jared E.

Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2023-05-01

OAAI

McNamara, Harold M.; Ramm, Beatrice; Toettcher, Jared E.

Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

CELL REPORTS

IF6.9

2022-03-01

OAAI

Singh, Anand P.; Wu, Ping; Ryabichko, Sergey; Raimundo, Joao; Swan, Michael; Wieschaus, Eric; Gregor, Thomas; Toettcher, Jared E.

A synthetic gene circuit for imaging-free detection of signaling pulses 用于无成像检测信号脉冲的合成基因电路

CELL SYSTEMS

IF7.7

2022-02-01

OAAI

Ravindran, Pavithran T.; McFann, Sarah; Thornton, Richard H.; Toettcher, Jared E.

Stress ball morphogenesis: How the lizard builds its lung

SCIENCE ADVANCES

IF12.5

2021-12-24

OAAI

Palmer, Michael A.; Nerger, Bryan A.; Goodwin, Katharine; Sudhakar, Anvitha; Lemke, Sandra B.; Ravindran, Pavithran T.; Toettcher, Jared E.; Kosmrlj, Andrej; Nelson, Celeste M.

研究方向