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W

Wen Y. Wu

university of groningen
H指数:10
被引数:1,498
浏览量:0

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Along for the ride: prophage-induced flagellar remodelling

随行效应：原噬菌体诱导的鞭毛重塑

Trends in Microbiology
IF14.9
2026-08-180
PRE
Victor D. Pool; Wen Y. Wu
Editing without Breaking: Sustained Gene Control via Epigenetic Rewriting

表观遗传重写实现持久基因调控：无损编辑

Current Opinion in Biomedical Engineering
IF4.2
2026-04-130
OA
Wen Y. Wu; Marianne G. Rots
Base editing both DNA strands in distinct editing windows with small CRISPR-associated effector Cas12f1

使用小型CRISPR相关效应蛋白Cas12f1在两个不同的编辑窗口中对DNA的两条链进行碱基编辑。

iScience
IF4.1
2025-11-120
OAAI
Thomas Swartjes; Evgenios Bouzetos; Belén Adiego-Pérez; Victor D. Pool; Raymond H.J. Staals; John van der Oost; Wen Y. Wu
Biology and applications of CRISPR-Cas12 and transposon-associated homologs

CRISPR-Cas12和转座子相关同源物的生物学及应用

NATURE BIOTECHNOLOGY
IF41.7
2024-12-040
PRE
Wu, Wen Y.; Adiego-Perez, Belen; van der Oost, John
TldR: TnpB's evolutionary shift from transposon nucleases to RNA-guided transcriptional regulators

TldR: TnpB从转座子核酸酶到RNA引导的转录调节因子的进化转变

TRENDS IN MICROBIOLOGY
IF14.9
2024-11-010
PRE
Mohanraju, Prarthana; Wu, Wen Y.
Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a
NUCLEIC ACIDS RESEARCH
IF13.1
2024-04-222
OAAI
Olivi, Lorenzo; Bagchus, Cleo; Pool, Victor; Bekkering, Ezra; Speckner, Konstantin; Offerhaus, Hidde; Wu, Wen Y.; Depken, Martin; Martens, Koen J. A.; Staals, Raymond H. J.; Hohlbein, Johannes
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2023-07-1710
OAAI
Omura, Satoshi N.; Nakagawa, Ryoya; Sudfeld, Christian; Warren, Ricardo Villegas; Wu, Wen Y.; Hirano, Hisato; Laffeber, Charlie; Kusakizako, Tsukasa; Kise, Yoshiaki; Lebbink, Joyce H. G.; Itoh, Yuzuru; van der Oost, John; Nureki, Osamu
The miniature CRISPR-Cas12m effector binds DNA to block transcription
MOLECULAR CELL
IF16.6
2022-12-0144
OAAI
Wu, Wen Y.; Mohanraju, Prarthana; Liao, Chunyu; Adiego-Perez, Belen; Creutzburg, Sjoerd C. A.; Makarova, Kira S.; Keessen, Karlijn; Lindeboom, Timon A.; Khan, Tahseen S.; Prinsen, Stijn; Joosten, Rob; Yan, Winston X.; Migur, Anzhela; Laffeber, Charlie; Scott, David A.; Lebbink, Joyce H. G.; Koonin, Eugene, V; Beisel, Chase L.; van der Oost, John
Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types
CRISPR JOURNAL
IF4
2022-08-011
OAAI
Wu, Wen Y.; Jackson, Simon A.; Almendros, Cristobal; Haagsma, Anna C.; Yilmaz, Suzan; Gort, Gerrit; van der Oost, John; Brouns, Stan J. J.; Staals, Raymond H. J.
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a
NUCLEIC ACIDS RESEARCH
IF13.1
2020-01-2869
OAAI
Creutzburg, Sjoerd; Wu, Wen Y.; Mohanraju, Prarthana; Swartjes, Thomas; Alkan, Ferhat; Gorodkin, Jan; Staals, Raymond H. J.; van der Oost, John
Genome editing by natural and engineered CRISPR-associated nucleases
NATURE CHEMICAL BIOLOGY
IF13.7
2018-06-18100
PREAI
Wu, Wen Y.; Lebbink, Joyce H. G.; Kanaar, Roland; Geijsen, Niels; van der Oost, John
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array (vol 35, pg 31, 2017)
NATURE BIOTECHNOLOGY
IF41.7
2017-02-0121
OAAI
Zetsche, Bernd; Heidenreich, Matthias; Mohanraju, Prarthana; Fedorova, Iana; Kneppers, Jeroen; DeGennaro, Ellen M.; Winblad, Nerges; Choudhury, Sourav R.; Abudayyeh, Omar; Gootenberg, Jonathan S.; Wu, Wen Y.; Scott, David A.; Severinov, Konstantin; van der Oost, John; Zhang, Feng
Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array
NATURE BIOTECHNOLOGY
IF41.7
2016-12-05778
OAAI
Zetsche, Bernd; Heidenreich, Matthias; Mohanraju, Prarthana; Fedorova, Iana; Kneppers, Jeroen; DeGennaro, Ellen M.; Winblad, Nerges; Choudhury, Sourav R.; Abudayyeh, Omar O.; Gootenberg, Jonathan S.; Wu, Wen Y.; Scott, David A.; Severinov, Konstantin; van der Oost, John; Zhang, Feng

研究方向

暂未获取到该数据
J
John van der Oost
H 指数:95论文数:536被引数:4.8万
P
Prarthana Mohanraju
H 指数:15论文数:23被引数:3,792
R
Raymond H.J. Staals
H 指数:33论文数:80被引数:5,348
J
Joyce H.G. Lebbink
H 指数:32论文数:139被引数:2,933
B
Belén Adiego-Pérez
H 指数:8论文数:14被引数:568
D
David Scott
H 指数:42论文数:91被引数:4.1万
V
Victor Pool
H 指数:2论文数:7被引数:16
J
Jonathan S. Gootenberg
H 指数:49论文数:116被引数:4.3万
O
Omar O. Abudayyeh
H 指数:46论文数:110被引数:3.7万
E
Ellen M. DeGennaro
H 指数:10论文数:16被引数:2,395