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H

Hyuk Lee

Korea Research Institute of Chemical Technology

24H指数
58论文数
2.2K被引数
收录论文 33
发表时间
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Electrosynthesis of 1,1-Bis(difluoromethyl)alkenes via Twofold C−H Difluoromethylation as Bioisosteres of Elusive 1,1-Enediols通过两倍c-h二氟甲基化作为难以捉摸的1，1-烯二醇的生物电子等排物电合成1，1-双 (二氟甲基) 烯烃
errNature Communications
IF15.7
err2026-05-20
err0
errOAAI
errSeonyoung Kim; Eunji Kwon; Sung Bum Park; Areum Park; Hyuk Lee; Hyunwoo Kim
err分享
err收藏
Targeting IP6 signaling to destabilize homologous recombination proteins to overcome PARP inhibitor resistance靶向IP6信号通路以破坏同源重组蛋白，克服PARP抑制剂耐药性
errNature Communications
IF15.7
err2026-04-04
err0
errOAAI
errSeon-gyeong Lee; Yuri Seo; Seula Jeong; Yuheon Chung; Sukyeong Kong; Minyoung Kim; Joon Ho Rhlee; Sihyeon Um; Bijoy P. Mathew; Saikat Maiti; Malleswara Rao Kuram; Mohamed Ahmed Abozeid; Areum Park; Ji-Na Yoo; Keon Woo Khim; Kyuwon Son; Enkhzul Amarsanaa; Kyunghan Kim; Sehoon Hong; Jiyeon Choi; In Bae Park; Eun A. Lee; Ji Hwan Jeon; Jun Hong Park; Joo Seok Han; Chan Young Park; Seyun Kim; Jang Hyun Choi; Sung You Hong; Min-Duk Seo; Hyuk Lee; Joo-Yong Lee; Kyungjae Myung
err分享
err收藏
Targeting iron regulatory protein 2 (IRP2) to disrupt iron metabolism enhances radiosensitivity through mitochondrial dysfunction in breast cancer cells靶向铁调节蛋白2（IRP2）以破坏铁代谢通过线粒体功能障碍增强乳腺癌细胞的放射敏感性
errCell Death Discovery
IF7
err2025-07-31
err0
errOAAI
errYe Yeong Jeong; Jieon Hwang; Areum Park; Sungmin Cho; Inyoung Cho; Soseul Won; You Me Shin; Sung Eun Kim; Chan Hoon Maeng; Jaemoon Yang; Minhee Ku; Hyuk Lee; Sang Joon Shin
err分享
err收藏
Discovery of a selective dual-specificity tyrosine phosphorylation-regulated kinase 1B inhibitor with anti-adipogenic and anti-diabetic activities发现一种具有抗脂肪生成和抗糖尿病活性的选择性双特异性酪氨酸磷酸化调控激酶1B抑制剂
errFrontiers in Pharmacology
IF4.8
err2025-07-29
err0
errOAAI
errSein Kang†; Yoon-Ju Na†; Kyoung Jin Choi; Won Hoon Jung; Areum Park; Jeonghui Im; Sung Bum Park; Byumseok Koh; Joo-Youn Lee; Kwang-Lae Hoe; Heung Jae Kim; Sang Joon Shin; Hyuk Lee; Ki Young Kim
err分享
err收藏
Inhibition of IRP2-dependent reprogramming of iron metabolism suppresses tumor growth in colorectal cancer
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-10-07
err0
errOAAI
errHwang, Jieon; Park, Areum; Kim, Chinwoo; Kim, Chang Gon; Kwak, Jaesung; Kim, Byungil; Shin, Hyunjin; Ku, Minhee; Yang, Jaemoon; Baek, Ayoung; Choi, Jiwon; Lim, Hocheol; No, Kyoung Tai; Zhao, Xianghua; Choi, Uyeong; Kim, Tae Il; Jeong, Kyu-Sung; Lee, Hyuk; Shin, Sang Joon
err分享
err收藏
Inhibition of IRP2-dependent reprogramming of iron metabolism suppresses tumor growth in colorectal cancer
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-08-23
err3
errOAAI
errHwang, Jieon; Park, Areum; Kim, Chinwoo; Kim, Chang Gon; Kwak, Jaesung; Kim, Byungil; Shin, Hyunjin; Ku, Minhee; Yang, Jaemoon; Baek, Ayoung; Choi, Jiwon; Lim, Hocheol; No, Kyoung Tai; Zhao, Xianghua; Choi, Uyeong; Kim, Tae Il; Jeong, Kyu-Sung; Lee, Hyuk; Shin, Sang Joon
err分享
err收藏
KS20226, a first-in-class IRP2 inhibitor, preferentially induces reprogramming of iron metabolism and suppresses tumor growth in colorectal cancer
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHwang, Jieon; Park, Areum; Kim, Chinwoo; Kim, Chang Gon; Kwak, Jaesung; Kim, Byungil; Shin, Hyunjin; Ku, Minhee; Yang, Jaemoon; Baek, Ayoung; Choi, Jiwon; Lim, Hocheol; No, Kyoung Tai; Zhao, Xianghua; Choi, Uyeong; Kim, Tae Il; Jeong, Kyu-Sung; Lee, Hyuk; Shin, Sang Joon
err分享
err收藏
Radical hydrodifluoromethylation of unsaturated C-C bonds via an electroreductively triggered two-pronged approach
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2022-08-11
err12
errOAAI
errKim, Seonyoung; Hwang, Keon Ha; Park, Hyeong Gyu; Kwak, Jaesung; Lee, Hyuk; Kim, Hyunwoo
err分享
err收藏
KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
errCELL REPORTS
IF6.9
err2022-07-01
err11
errOAAI
errKim, Jaehee; Park, Areum; Hwang, Jieon; Zhao, Xianghua; Kwak, Jaesung; Kim, Hyun Woo; Ku, Minhee; Yang, Jaemoon; Kim, Tae Il; Jeong, Kyu-Sung; Choi, Uyeong; Lee, Hyuk; Shin, Sang Joon
err分享
err收藏
Development of in vitro three-dimensional drug screening system for obesity-related metabolic syndrome
errJOURNAL OF PHARMACOLOGICAL SCIENCES
IF2.9
err2022-04-01
err5
errOAAI
errChoi, Kyoung Jin; Lee, Joon Ho; Park, Sung Bum; Na, Yoon-Ju; Jung, Won Hoon; Lee, Hyuk; Kim, Ki Young
err分享
err收藏
Synthesis of 1H-Indazoles via Silver(I)-Mediated Intramolecular Oxidative C-H Bond Amination
errACS OMEGA
IF4.3
err2021-02-23
err11
errOAAI
errPark, Areum; Jeong, Kyu-Sung; Lee, Hyuk; Kim, Hyunwoo
err分享
err收藏
DISCOVERY OF A NOVEL EP2 AND EP4 DUAL ANTAGONIST
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2020-12-10
err0
PREAI
errLee, Yeri; Kim, Hyun Jin; Kim, Donggeon; Lee, Joo Youn; Yun, Chang Soo; Lee, Hyuk; Shin, Young Sook; Han, Soo Bong; Lim, Sang Kyun
err分享
err收藏
Copper-Catalyzed 1,2-Bistrifluoromethylation of Terminal Alkenes铜催化的末端烯烃的1，2-二三氟甲基化
errADVANCED SYNTHESIS & CATALYSIS
IF4
err2019-03-06
err17
PREAI
errOh, Hyunseok; Park, Areum; Jeong, Kyu-Sung; Han, Soo Bong; Lee, Hyuk
err分享
err收藏
Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B
errACS CATALYSIS
IF13.1
err2016-10-06
err24
PREAI
errPark, Areum; Kim, Sunmin; Park, Jeemin; Joe, Saerom; Min, Bora; Oh, Joonyoung; Song, Jaekwang; Park, SangYoun; Park, Seongsoon; Lee, Hyuk
err分享
err收藏
Biosynthesis of poly(2-hydroxyisovalerate-co-lactate) by metabolically engineered Escherichia coli
errBIOTECHNOLOGY JOURNAL
IF3.1
err2016-09-27
err25
PREAI
errYang, Jung Eun; Kim, Je Woong; Oh, Young Hoon; Choi, So Young; Lee, Hyuk; Park, A-Reum; Shin, Jihoon; Park, Si Jae; Lee, Sang Yup
err分享
err收藏
One-step fermentative production of poly(lactate-co-glycolate) from carbohydrates in Escherichia coli从大肠杆菌中的碳水化合物一步发酵生产聚 (乳酸-乙醇酸共聚物)
errNATURE BIOTECHNOLOGY
IF41.7
err2016-03-07
err186
PREAI
errChoi, So Young; Park, Si Jae; Kim, Won Jun; Yang, Jung Eun; Lee, Hyuk; Shin, Jihoon; Lee, Sang Yup
err分享
err收藏
Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy
errEMBO MOLECULAR MEDICINE
IF8.3
err2016-03-03
err38
errOAAI
errKim, Hyun-Yi; Choi, Sehee; Yoon, Ji-Hye; Lim, Hwan Jung; Lee, Hyuk; Choi, Jiwon; Ro, Eun Ji; Heo, Jung-Nyoung; Lee, Weontae; No, Kyoung Tai; Choi, Kang-Yell
err分享
err收藏
Repositioning Potential of PAK4 to Osteoclastic Bone Resorption
errJOURNAL OF BONE AND MINERAL RESEARCH
IF5.9
err2015-01-31
err7
PREAI
errChoi, Sik-Won; Yeon, Jeong-Tae; Ryu, Byung Jun; Kim, Kwang-Jin; Moon, Seong-Hee; Lee, Hyuk; Lee, Myeung Su; Lee, Sam Youn; Heo, Jin-Chul; Park, Sang-Joon; Kim, Seong Hwan
err分享
err收藏
Metabolic Engineering of Ralstonia eutropha for the Production of Polyhydroxyalkanoates From Sucrose
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2014-10-21
err63
PREAI
errPark, Si Jae; Jang, Young-Ah; Noh, Won; Oh, Young Hoon; Lee, Hyuk; David, Yokimiko; Baylon, Mary Grace; Shin, Jihoon; Yang, Jung Eun; Choi, So Young; Lee, Seung Hwan; Lee, Sang Yup
err分享
err收藏
PF-3758309, p21-activated kinase 4 inhibitor, suppresses migration and invasion of A549 human lung cancer cells via regulation of CREB, NF-κB, and β-catenin signalings
errMOLECULAR AND CELLULAR BIOCHEMISTRY
IF3.7
err2013-12-24
err48
PREAI
errRyu, Byung Jun; Lee, Hyuk; Kim, Seong-Ho; Heo, Jung-Nyoung; Choi, Sik-Won; Yeon, Jeong-Tae; Lee, Jeongmin; Lee, Jongsung; Cho, Jae Youl; Kim, Seong Hwan; Lee, Sang Yeol
err分享
err收藏

研究方向

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合作学者
合作期刊
S
Sang Yup Lee
H 指数: 137 · 论文数: 3.1K
T
T. Don Tilley
H 指数: 90 · 论文数: 1.3K
C
Chan Beum Park
H 指数: 79 · 论文数: 331
J
Jae Youl Cho
H 指数: 69 · 论文数: 618
D
Do Kyung Kim
H 指数: 66 · 论文数: 678
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