Shiming Chen

Washington University School of Medicine

H指数:36

被引数:5,043

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The long noncoding RNA Peanut (Gm11454) biases progenitors towards neurogenesis and rod photoreceptor differentiation during postnatal retinal development

Peanut (<em>Gm11454</em>)长链非编码RNA在出生后视网膜发育过程中促进前体细胞向神经发生和视杆细胞光感受器分化

Developmental Biology

IF2.1

2026-09-070

OAAI

Aberrant retinal structure and vasculature in mouse models of dominant retinopathies caused by CRX homeodomain mutations

小鼠CRX同源结构域突变所致显性视网膜病变模型的视网膜结构和血管异常

Scientific Reports

IF3.9

2026-07-030

Intratonsillar Immunotherapy: A Convenient and Effective Alternative to Subcutaneous Immunotherapy for Allergic Rhinitis

扁桃体内免疫疗法：一种治疗过敏性鼻炎的便捷且有效的皮下免疫疗法替代方案

Research

IF10.7

2025-01-160

Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors

GENOME RESEARCH

IF5.5

2024-02-144

OAAI

Transcriptional precision in photoreceptor development and diseases - Lessons from 25 years of CRX research

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2024-02-131

OAAI

Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation

GENOME BIOLOGY

IF9.4

2023-11-274

OAAI

Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms

ELIFE

IF0

2023-11-146

OAAI

Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity

SCIENTIFIC REPORTS

IF3.9

2023-08-091

OAAI

Disease-causing mutations in genes encoding transcription factors critical for photoreceptor development

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2023-04-274

OAAI

Fenofibrate Reduces the Severity of Neuroretinopathy in a Type 2 Model of Diabetes without Inducing Peroxisome Proliferator-Activated Receptor Alpha-Dependent Retinal Gene Expression

JOURNAL OF CLINICAL MEDICINE

IF2.9

2020-12-3110

OAAI

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

SCIENTIFIC REPORTS

IF3.9

2018-08-0913

OAAI

CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

EPIGENETICS & CHROMATIN

IF3.5

2018-08-0134

OAAI

Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision

JCI INSIGHT

IF6.1

2018-01-1115

OAAI

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

Crx-L253X突变在TVRM65小鼠中产生显性光感受器缺陷

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2017-09-1310

OAAI

CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2016-07-1523

OAAI

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

GENOME BIOLOGY

IF9.4

2015-09-0136

OAAI

Mechanistically Distinct Mouse Models for CRX-Associated Retinopathy

PLOS GENETICS

IF3.7

2014-02-0651

OAAI

Active opsin loci adopt intrachromosomal loops that depend on the photoreceptor transcription factor network

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-10-1736

OAAI

Transcriptional Regulation of Neural Retina Leucine Zipper (Nrl), a Photoreceptor Cell Fate Determinant

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2011-10-0155

OAAI

The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons

DEVELOPMENT

IF3.6

2011-06-0153

OAAI

Shiming Chen

个人简介

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