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B

Bryce L. Sopher

university of washington
H指数:43
被引数:7,786

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Neuromuscular junction transcriptome analysis of spinal and bulbar muscular atrophy mice implicates sarcomere gene expression and calcium flux dysregulation in disease pathogenesis

脊髓和球部肌萎缩小鼠的神经肌肉接头转录组分析表明，肌原纤维基因表达和钙离子流失调与疾病发生机制有关。

HUMAN MOLECULAR GENETICS
IF3.2
2025-05-140
PRE
Gromova, Anastasia; Cha, Byeonggu; Nguyen, Nhat; Garg, Diya; Coscolluela, Connor; Strickland, Laura M.; Luong, David; Longo, Fabiana; Sopher, Bryce L.; ElMallah, Mai K.; La Spada, Albert R.
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy (vol 24, pg 427, 2018)
NATURE MEDICINE
IF50
2024-01-080
OA
Badders, Nisha M.; Korff, Ane; Miranda, Helen C.; Vuppala, Pradeep K.; Smith, Rebecca B.; Winborn, Brett J.; Quemin, Emmanuelle R.; Sopher, Bryce L.; Dearman, Jennifer; Messing, James; Kim, Nam Chul; Moore, Jennifer; Freibaum, Brian D.; Kanagaraj, Anderson P.; Fan, Baochang; Tillman, Heather; Chen, Ping-Chung; Wang, Yingzhe; Freeman III, Burgess B.; Li, Yimei; Kim, Hong Joo; La Spada, Albert R.; Taylor, J. Paul
Alternative splicing in a presenilin 2 variant associated with Alzheimer disease
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
IF3.9
2019-03-1032
OAAI
Braggin, Jacquelyn E.; Bucks, Stephanie A.; Course, Meredith M.; Smith, Carole L.; Sopher, Bryce; Osnis, Leah; Shuey, Kiel D.; Domoto-Reilly, Kimiko; Caso, Christina; Kinoshita, Chizuru; Scherpelz, Kathryn P.; Cross, Chloe; Grabowski, Thomas; Nik, Seyyed H. M.; Newman, Morgan; Garden, Gwenn A.; Leverenz, James B.; Tsuang, Debby; Latimer, Caitlin; Gonzalez-Cuyar, Luis F.; Keene, Christopher Dirk; Morrison, Richard S.; Rhoads, Kristoffer; Wijsman, Ellen M.; Dorschner, Michael O.; Lardelli, Michael; Young, Jessica E.; Valdmanis, Paul N.; Bird, Thomas D.; Jayadev, Suman
Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology
ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2019-02-2613
OAAI
Wenzel, H. Juergen; Murray, Karl D.; Haify, Saif N.; Hunsaker, Michael R.; Schwartzer, Jared J.; Kim, Kyoungmi; La Spada, Albert R.; Sopher, Bryce L.; Hagerman, Paul J.; Raske, Christopher; Severijnen, Lies-Anne W. F. M.; Willemsen, Rob; Hukema, Renate K.; Berman, Robert F.
Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy
NATURE MEDICINE
IF50
2018-03-0538
OAAI
Badders, Nisha M.; Korff, Ane; Miranda, Helen C.; Vuppala, Pradeep K.; Smith, Rebecca B.; Winborn, Brett J.; Quemin, Emmanuelle R.; Sopher, Bryce L.; Dearman, Jennifer; Messing, James; Kim, Nam Chul; Moore, Jennifer; Freibaum, Brian D.; Kanagaraj, Anderson P.; Fan, Baochang; Tillman, Heather; Chen, Ping-Chung; Wang, Yingzhe; Freeman, Burgess B., III; Li, Yimei; Kim, Hong Joo; La Spada, Albert R.; Taylor, J. Paul
Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal
CELL CYCLE
IF3.4
2018-02-2217
OAAI
Ferreccio, Amy; Mathieu, Julie; Detraux, Damien; Somasundaram, Logeshwaran; Cavanaugh, Christopher; Sopher, Bryce; Fischer, Karin; Bello, Thomas; Hussein, Abdiasis M.; Levy, Shiri; Cook, Savannah; Sidhu, Sonia B.; Artoni, Filippo; Palpant, Nathan J.; Reinecke, Hans; Wang, Yuliang; Paddison, Patrick; Murry, Charles; Jayadev, Suman; Ware, Carol; Ruohola-Baker, Hannele
PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically
NATURE MEDICINE
IF50
2015-12-0780
OAAI
Dickey, Audrey S.; Pineda, Victor V.; Tsunemi, Taiji; Liu, Patrick P.; Miranda, Helen C.; Gilmore-Hall, Stephen K.; Lomas, Nicole; Sampat, Kunal R.; Buttgereit, Anne; Torres, Mark-Joseph Manalang; Flores, April L.; Arreola, Martin; Arbez, Nicolas; Akimov, Sergey S.; Gaasterland, Terry; Lazarowski, Eduardo R.; Ross, Christopher A.; Yeo, Gene W.; Sopher, Bryce L.; Magnuson, Gavin K.; Pinkerton, Anthony B.; Masliah, Eliezer; La Spada, Albert R.
Loss of endophilin-B1 exacerbates Alzheimer's disease pathology

endophilin-B1的丧失加剧了阿尔茨海默病的病理学

BRAIN
IF11.7
2015-05-1630
OAAI
Wang, David B.; Kinoshita, Yoshito; Kinoshita, Chizuru; Uo, Takuma; Sopher, Bryce L.; Cudaback, Eiron; Keene, C. Dirk; Bilousova, Tina; Gylys, Karen; Case, Amanda; Jayadev, Suman; Wang, Hong-Gang; Garden, Gwenn A.; Morrison, Richard S.
Let-7 Coordinately Suppresses Components of the Amino Acid Sensing Pathway to Repress mTORC1 and Induce Autophagy
CELL METABOLISM
IF30.9
2014-10-0170
OAAI
Dubinsky, Amy N.; Dastidar, Somasish Ghosh; Hsu, Cynthia L.; Zahra, Rabaab; Djakovic, Stevan N.; Duarte, Sonia; Esau, Christine C.; Spencer, Brian; Ashe, Travis D.; Fischer, Kimberlee M.; MacKenna, Deidre A.; Sopher, Bryce L.; Masliah, Eliezer; Gaasterland, Terry; Chau, B. Nelson; de Almeida, Luis Pereira; Morrison, Bradley E.; La Spada, Albert R.

研究方向

暂未获取到该数据
A
Albert R. La Spada
H 指数:62论文数:254被引数:2.1万
C
Carol B. Ware
H 指数:46论文数:110被引数:1.3万
G
Gwenn A. Garden
H 指数:45论文数:112被引数:8,339
R
Richard S. Morrison
H 指数:57论文数:164被引数:1.0万
S
Suman Jayadev
H 指数:39论文数:224被引数:7,926
G
George M. Martin
H 指数:75论文数:536被引数:2.5万
R
Randell T. Libby
H 指数:18论文数:35被引数:3,254
C
Craig L. Bennett
H 指数:28论文数:71被引数:7,017
C
C. Kinoshita
H 指数:21论文数:105被引数:3,166
J
J. Paul Taylor
H 指数:93论文数:290被引数:6.0万