未登录 Activity of novel RNA therapeutics to overcome resistance to immune checkpoint blockade O'Ketch, Marvin; Kiefer, Jeffrey A.; Rasale, Dnyanesh; Weiner, Warren S.; Castano, Lizette A.; Azorsa, Nathalie A.; Lee, David W.; Barnhart, Kerry M.; Mousses, Spyro; Azorsa, David O. 分享 收藏
A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice Boudreau, Matthew W.; Duraki, Darjan; Wang, Lawrence; Mao, Chengjian; Kim, Ji Eun; Henn, Madeline A.; Tang, Bingtao; Fanning, Sean W.; Kiefer, Jeffrey; Tarasow, Theodore M.; Bruckheimer, Elizabeth M.; Moreno, Ramon; Mousses, Spyro; Greene, Geoffrey L.; Roy, Edward J.; Park, Ben Ho; Fan, Timothy M.; Nelson, Erik R.; Hergenrother, Paul J.; Shapiro, David J. 分享 收藏
Quantitative regression of estrogen receptor alpha positive breast cancer Boudreau, Matthew W.; Hergenrother, Paul J.; Duraki, Darjan; Wang, Lawrence; Mao, Chengjian; Park, Ben H.; Fan, Tim M.; Nelson, Eric R.; Shapiro, David J.; Moreno, Ramon; Bruckheimer, Elizabeth; Kiefer, Jeffrey; Tarasow, Theodore M. 分享 收藏
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis Hendricks, William P. D.; Zismann, Victoria; Sivaprakasam, Karthigayini; Legendre, Christophe; Poorman, Kelsey; Tembe, Waibhav; Perdigones, Nieves; Kiefer, Jeffrey; Liang, Winnie; DeLuca, Valerie; Stark, Mitchell; Ruhe, Alison; Froman, Roe; Duesbery, Nicholas S.; Washington, Megan; Aldrich, Jessica; Neff, Mark W.; Huentelman, Matthew J.; Hayward, Nicholas; Brown, Kevin; Thamm, Douglas; Post, Gerald; Khanna, Chand; Davis, Barbara; Breen, Matthew; Sekulic, Alexander; Trent, Jeffrey M. 分享 收藏
Elucidating cancer hallmark context from glioma MR imaging and RNA expression data Sui, Yunxia; Rusu, Mirabela; Shanbhag, Dattesh; Patil, Uday; Kiefer, Jeffrey; Barnholtz-Sloan, Jill; Berens, Michael; Ginty, Fiona; John, Graf; Gupta, Sandeep; Kodira, Chinnappa; Newberg, Lee; Raghunath, Sushravya; Sood, Anup; Raghunath, Sushravya 分享 收藏
Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma Liang, Winnie S.; Hendricks, William; Kiefer, Jeffrey; Schmidt, Jessica; Sekar, Shobana; Carpten, John; Craig, David W.; Adkins, Jonathan; Cuyugan, Lori; Manojlovic, Zarko; Halperin, Rebecca F.; Helland, Adrienne; Nasser, Sara; Legendre, Christophe; Hurley, Laurence H.; Sivaprakasam, Karthigayini; Johnson, Douglas B.; Crandall, Holly; Busam, Klaus J.; Zismann, Victoria; De Luca, Valerie; Lee, Jeeyun; Sekulic, Aleksandar; Ariyan, Charlotte E.; Sosman, Jeffrey; Trent, Jeffrey 分享 收藏
Targeting the platelet derived growth factor receptor (PDGFR) with the receptor tyrosine kinase inhibitor ponatinib in small cell carcinoma of the ovary, hypercalcemic type Lang, Jessica Diane; Hendricks, William; Ramos, Pilar; Yin, Holly; Sereduk, Chris; Kiefer, Jeffrey; Wang, Yemin; Karnezis, Anthony N.; Weissman, Bernard; Huntsman, David; Trent, Jeffrey 分享 收藏
Interpreting glioma MR imaging and somatic mutations in a cancer hallmark context Graf, John; Rusu, Mirabela; Sui, Yunxia; Shanbhag, Dattesh; Patil, Uday; Kiefer, Jeffrey; Barnholtz-Sloan, Jill; Berens, Michael; Ginty, Fiona; Gupta, Sandeep; Kodira, Chinnappa; Newberg, Lee; Raghunath, Sushravya; Sood, Anup 分享 收藏
Human mesodermal-derived CNS metastasis-associated stromal cells induce a fibrotic response to limit tumor growth Legendre, Christophe; Gooden, Gerald C.; Johnson, Kyle N.; Martinez, Rae Anne; Bernstein, Mark; Glen, Jennifer; Kiefer, Jeffrey; Hinek, Aleksander; Toms, Steven A.; Salhia, Bodour 分享 收藏
Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma Liang, Winnie S.; Hendricks, William; Kiefer, Jeffrey; Schmidt, Jessica; Sekar, Shobana; Carpten, John; Craig, David W.; Adkins, Jonathan; Cuyugan, Lori; Manojlovic, Zarko; Halperin, Rebecca F.; Helland, Adrienne; Nasser, Sara; Legendre, Christophe; Hurley, Laurence H.; Sivaprakasam, Karthigayini; Johnson, Douglas B.; Crandall, Holly; Busam, Klaus J.; Zismann, Victoria; Deluca, Valerie; Lee, Jeeyun; Sekulic, Aleksandar; Ariyan, Charlotte E.; Sosman, Jeffrey; Trent, Jeffrey 分享 收藏
Integrated genomic analysis of survival outliers in glioblastoma Peng, Sen; Dhruv, Harshil; Armstrong, Brock; Salhia, Bodour; Legendre, Christophe; Kiefer, Jeffrey; Parks, Julianna; Virk, Selene; Sloan, Andrew E.; Ostrom, Quinn T.; Barnholtz-Sloan, Jill S.; Tran, Nhan L.; Berens, Michael E. 分享 收藏
Integrated genomic analysis of survival outliers in glioblastoma Peng, Sen; Dhurv, Harshil; Armstrong, Brock; Kiefer, Jeffrey; Salhia, Bodour; Ross, Julianna; Legendre, Christophe; Virk, Selene; Sloan, Andrew E.; Ostrom, Quinn T.; Barnholtz-Sloan, Jill; Tran, Nhan L.; Berens, Michael E. 分享 收藏
microRNA changes in liver tissue associated with fibrosis progression inpatients with hepatitis C Van Keuren-Jensen, Kendall R.; Malenica, Ivana; Courtright, Amanda L.; Ghaffari, Layla T.; Starr, Alex P.; Metpally, Raghu P.; Beecroft, Taylor A.; Carlson, Elizabeth W. J.; Kiefer, Jeffrey A.; Pockros, Paul J.; Rakela, Jorge 分享 收藏
Pilot Trial of Selecting Molecularly Guided Therapy for Patients with Non-V600 BRAF-Mutant Metastatic Melanoma: Experience of the SU2C/MRA Melanoma Dream Team LoRusso, Patricia M.; Boerner, Scott A.; Pilat, Mary Jo; Forman, Karen M.; Zuccaro, Clarice Y.; Kiefer, Jeffrey A.; Liang, Winnie S.; Hunsberger, Sally; Redman, Bruce G.; Markovic, Svetomir N.; Sekulic, Aleksandar; Bryce, Alan H.; Joseph, Richard W.; Cowey, C. Lance; Fecher, Leslie Anne; Sosman, Jeffrey Alan; Chapman, Paul B.; Schwartz, Gary K.; Craig, David W.; Carpten, John D.; Trent, Jeffrey M. 分享 收藏
Toward precision medicine in glioblastoma: the promise and the challenges 胶质母细胞瘤的精准医学: 前景与挑战 Prados, Michael D.; Byron, Sara A.; Tran, Nhan L.; Phillips, Joanna J.; Molinaro, Annette M.; Ligon, Keith L.; Wen, Patrick Y.; Kuhn, John G.; Mellinghoff, Ingo K.; de Groot, John F.; Colman, Howard; Cloughesy, Timothy F.; Chang, Susan M.; Ryken, Timothy C.; Tembe, Waibhav D.; Kiefer, Jeffrey A.; Berens, Michael E.; Craig, David W.; Carpten, John D.; Trent, Jeffrey M. 分享 收藏
The rare, highly malignant small cell carcinoma of the ovary displays common inactivating germline and somatic mutations in the tumor suppressor SMARCA4 Ramos, Pilar; Karnezis, Anthony; Craig, David; Sekulic, Aleksandar; Russell, Megan; Hendricks, William; Barrett, Michael; Shumansky, Karey; Yang, Yidong; Shah, Sohrab; Prentice, Leah; Marra, Marco; Kiefer, Jeffrey; Zismann, Victoria; McEachron, Troy; Salhia, Bodour; Pressey, Joseph; Farley, John; Anthony, Stephen; Roden, Richard; Cunliffe, Heather; Huntsman, David; Trent, Jeffrey 分享 收藏
Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4 Ramos, Pilar; Karnezis, Anthony N.; Craig, David W.; Sekulic, Aleksandar; Russell, Megan L.; Hendricks, William P. D.; Corneveaux, Jason J.; Barrett, Michael T.; Shumanskys, Karey; Yang, Yidong; Shah, Sohrab P.; Prentice, Leah M.; Marra, Marco A.; Kiefer, Jeffrey; Zismann, Victoria L.; McEachron, Troy A.; Salhia, Bodour; Prat, Jaime; D'Angelo, Emanuela; Clarke, Blaise A.; Pressey, Joseph G.; Farley, John H.; Anthony, Stephen P.; Roden, Richard B. S.; Cunliffe, Heather E.; Huntsman, David G.; Trent, Jeffrey M. 分享 收藏
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Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities Craig, David W.; O'Shaughnessy, Joyce A.; Kiefer, Jeffrey A.; Aldrich, Jessica; Sinari, Shripad; Moses, Tracy M.; Wong, Shukmei; Dinh, Jennifer; Christoforides, Alexis; Blum, Joanne L.; Aitelli, Cristi L.; Osborne, Cynthia R.; Izatt, Tyler; Kurdoglu, Ahmet; Baker, Angela; Koeman, Julie; Barbacioru, Catalin; Sakarya, Onur; De La Vega, Francisco M.; Siddiqui, Asim; Hoang, Linh; Billings, Paul R.; Salhia, Bodour; Tolcher, Anthony W.; Trent, Jeffrey M.; Mousses, Spyro; Von Hoff, Daniel; Carpten, John D. 分享 收藏
Identification of key tumorigenic pathways in pancreatic adenocarcinoma patients using massively parallel DNA and RNA sequencing Liang, Winnie S.; Craig, David W.; Carpten, John; Borad, Mitesh J.; Demeure, Michael J.; Weiss, Glen J.; Kiefer, Jeffrey A.; Posner, Richard; Hostetter, Galen H.; Izatt, Tyler; Sinari, Shripad; Christoforides, Alexis; Aldrich, Jessica; Kurdoglu, Ahmet; Phillips, Lori; Benson, Hollie; Baker, Angela; Han, Haiyong; Lake, Douglas; Stites, Edward C.; Ramanathan, Ramesh K.; Fonseca, Rafael; Stewart, A. Keith; Von Hoff, Daniel 分享 收藏