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An enzymatic dual-oxa Diels-Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (-)-anthrabenzoxocinone 酶催化的双氧杂Diels-Alder反应构建了(-)-anthrabenzoxocinone的氧桥三环缩醛单元 Yan, Xiaoli; Jia, Xinying; Luo, Zhenyao; Ji, Shunjia; Zhang, Meng-Jie; Zhang, Hui; Yu, Mingjia; Orts, Julien; Jiang, Kai; Lin, Zhi; Deng, Zixin; Kong, Xu-Dong; Kobe, Bostjan; Zhao, Yi-Lei 分享 收藏
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Gold Nanoparticles as a Platform for Delivery of Immunogenic Peptides to THP-1 Derived Macrophages: Insights into Nanotoxicity Zuniga, Eduardo; Contreras-Trigo, Braulio; Buchert, Jorge; Saez-Ahumada, Fabian; Hernandez, Leonardo; Fica-Leon, Victor; Nova-Lamperti, Estefania; Kobe, Bostjan; Guzman, Fanny; Diaz-Garcia, Victor; Guzman-Gutierrez, Enrique; Oyarzun, Patricio 分享 收藏
Structural basis for TIR domain-mediated innate immune signaling by Toll- like receptor adaptors TRIF and TRAM TIR结构域介导的Toll样受体接头蛋白TRIF和TRAM的固有免疫信号传导的结构基础 Manik, Mohammad K.; Pan, Mengqi; Xiao, Le; Gu, Weixi; Kim, Hyoyoung; Pospich, Sabrina; Hedger, Andrew; Vajjhala, Parimala R.; Lee, Morris Y. L.; Qian, Xiaoqi; Landsberg, Michael J.; Ve, Thomas; Nanson, Jeffrey D.; Raunser, Stefan; Stacey, Katryn J.; Wu, Hao; Kobe, Bostjan 分享 收藏
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Structural characterization of macro domain-containing Thoeris antiphage defense systems Shi, Yun; Masic, Veronika; Mosaiab, Tamim; Rajaratman, Premraj; Hartley-Tassell, Lauren; Sorbello, Mitchell; Goulart, Cassia C.; Vasquez, Eduardo; Mishra, Biswa P.; Holt, Stephanie; Gu, Weixi; Kobe, Bostjan; Ve, Thomas 分享 收藏
Small molecule drug discovery targeting the JAK-STAT pathway 靶向jak-stat通路的小分子药物发现 Lv, You; Mi, Pengbing; Babon, Jeffrey J.; Fan, Guohuang; Qi, Jianxun; Cao, Longxing; Lang, Jiajia; Zhang, Jin; Wang, Faming; Kobe, Bostjan 分享 收藏
o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2 Rahaman, Md. Habibur; Thygesen, Sara J.; Maxwell, Michael J.; Kim, Hyoyoung; Mudai, Prerna; Nanson, Jeffrey D.; Jia, Xinying; Vajjhala, Parimala R.; Hedger, Andrew; Vetter, Irina; Haselhorst, Thomas; Robertson, Avril A. B.; Dymock, Brian; Ve, Thomas; Mobli, Mehdi; Stacey, Katryn J.; Kobe, Bostjan 分享 收藏
Hfe Permease and Haemophilus influenzae Manganese Homeostasis Ganio, Katherine; Nasreen, Marufa; Yang, Zihao; Maunders, Eve A.; Luo, Zhenyao; Hossain, Sheikh Imamul; Ngu, Dalton H. Y.; Ellis, Daniel; Gu, Jin; Neville, Stephanie L.; Wilksch, Jonathan; Gunn, Adam P.; Whittall, Jonathan J.; Kobe, Bostjan; Deplazes, Evelyne; Kappler, Ulrike; Mcdevitt, Christopher A. 分享 收藏
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Discovery of C-5 Pyrazole-Substituted Pyrrolopyridine Derivatives as Potent and Selective Inhibitors for Janus Kinase 1 Lang, Jia-Jia; Lv, You; Kobe, Bostjan; Chen, Hongfei; Tan, Yan; Chen, Limei; Wang, Xuechuan; Mi, Pengbing; Zheng, Xing; Lin, Ying-Wu 分享 收藏
Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1 Tao, Le; Yang, Guangyue; Sun, Tiantian; Tao, Jie; Zhu, Chan; Yu, Huimin; Cheng, Yalan; Yang, Zongguo; Xu, Mingyi; Jiang, Yuefeng; Zhang, Wei; Wang, Zhiyi; Ma, Wenting; Wu, Liu; Xue, Dongying; Wang, Dongxue; Yang, Wentao; Zhao, Yongjuan; Horsefield, Shane; Kobe, Bostjan; Zhang, Zhe; Tang, Zongxiang; Li, Qigen; Zhai, Qiwei; Dooley, Steven; Seki, Ekihiro; Liu, Ping; Xu, Jianrong; Chen, Hongzhuan; Liu, Cheng 分享 收藏
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