未登录Ready-to-use iPSC-derived microglia progenitors for the treatment of CNS disease in mouse models of neuropathic mucopolysaccharidoses
Douvaras, Panagiotis; Buenaventura, Diego F.; Sun, Bruce; Lepack, Ashley; Baker, Elizabeth; Simpson, Elizabeth; Ebel, Mark; Lallos, Gregory; LoSchiavo, Deven; Stitt, Nicholas; Adams, Nathaniel; McAuliffe, Conor; Forton-Juarez, Ana; Kosmyna, Brian; Pereira, Elizabeth; Burnett, Benjamin; Dilworth, David; Fisher, Stephanie; Wang, Jing; Tonge, Peter; Tomishima, Mark; Paladini, Carlos; Wilkinson, Dan; Soh, Chew-Li; Srinivas, Maya; Patsch, Christoph; Irion, Stefan .png)
分享.png)
收藏Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2发现一种有效且选择性的靶向NSD2降解剂，用于还原H3K36me2Hanley, Ronan P.; Nie, David Y.; Tabor, John R.; Li, Fengling; Sobh, Amin; Xu, Chenxi; Barker, Natalie K.; Dilworth, David; Hajian, Taraneh; Gibson, Elisa; Szewczyk, Magdalena M.; Brown, Peter J.; Barsyte-Lovejoy, Dalia; Herring, Laura E.; Wang, Gang Greg; Licht, Jonathan D.; Vedadi, Masoud; Arrowsmith, Cheryl H.; James, Lindsey I. 分享 收藏 A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization靶向PWWP结构域的化学探针改变了NSD2核仁定位Dilworth, David; Hanley, Ronan P.; de Freitas, Renato Ferreira; Allali-Hassani, Abdellah; Zhou, Mengqi; Mehta, Naimee; Marunde, Matthew R.; Ackloo, Suzanne; Machado, Raquel Arminda Carvalho; Yazdi, Aliakbar Khalili; Owens, Dominic D. G.; Vu, Victoria; Nie, David Y.; Alqazzaz, Mona; Marcon, Edyta; Li, Fengling; Chau, Irene; Bolotokova, Albina; Qin, Su; Lei, Ming; Liu, Yanli; Szewczyk, Magdalena M.; Dong, Aiping; Kazemzadeh, Sina; Abramyan, Tigran; Popova, Irina K.; Hall, Nathan W.; Meiners, Matthew J.; Cheek, Marcus A.; Gibson, Elisa; Kireev, Dmitri; Greenblatt, Jack F.; Keogh, Michael-C; Min, Jinrong; Brown, Peter J.; Vedadi, Masoud; Arrowsmith, Cheryl H.; Barsyte-Lovejoy, Dalia; James, Lindsey, I; Schapira, Matthieu 分享 收藏 Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2de Freitas, Renato Ferreira; Liu, Yanli; Szewczyk, Magdalena M.; Mehta, Naimee; Li, Fengling; McLeod, David; Zepeda-Velazquez, Carlos; Dilworth, David; Hanley, Ronan P.; Gibson, Elisa; Brown, Peter J.; Al-Awar, Rima; James, Lindsey, I; Arrowsmith, Cheryl H.; Barsyte-Lovejoy, Dalia; Min, Jinrong; Vedadi, Masoud; Schapira, Matthieu; Allali-Hassani, Abdellah 分享 收藏 Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response (vol 11, 2396, 2020)Szewczyk, Magdalena M.; Ishikawa, Yoshinori; Organ, Shawna; Sakai, Nozomu; Li, Fengling; Halabelian, Levon; Ackloo, Suzanne; Couzens, Amber L.; Eram, Mohammad; Dilworth, David; Fukushi, Hideto; Harding, Rachel; dela Sena, Carlo C.; Sugo, Tsukasa; Hayashi, Kozo; McLeod, David; Zepeda, Carlos; Aman, Ahmed; Sanchez-Osuna, Maria; Bonneil, Eric; Takagi, Shinji; Al-Awar, Rima; Tyers, Mike; Richard, Stephane; Takizawa, Masayuki; Gingras, Anne-Claude; Arrowsmith, Cheryl H.; Vedadi, Masoud; Brown, Peter J.; Nara, Hiroshi; Barsyte-Lovejoy, Dalia 分享 收藏 Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress responseSzewczyk, Magdalena M.; Ishikawa, Yoshinori; Organ, Shawna; Sakai, Nozomu; Li, Fengling; Halabelian, Levon; Ackloo, Suzanne; Couzens, Amber L.; Eram, Mohammad; Dilworth, David; Fukushi, Hideto; Harding, Rachel; dela Sena, Carlo C.; Sugo, Tsukasa; Hayashi, Kozo; McLeod, David; Zepeda, Carlos; Aman, Ahmed; Sanchez-Osuna, Maria; Bonneil, Eric; Takagi, Shinji; Al-Awar, Rima; Tyers, Mike; Richard, Stephane; Takizawa, Masayuki; Gingras, Anne-Claude; Arrowsmith, Cheryl H.; Vedadi, Masoud; Brown, Peter J.; Nara, Hiroshi; Barsyte-Lovejoy, Dalia 分享 收藏 Discovery of a chemical probe for PRDM9Allali-Hassani, Abdellah; Szewczyk, Magdalena M.; Ivanochko, Danton; Organ, Shawna L.; Bok, Jabez; Ho, Jessica Sook Yuin; Gay, Florence P. N.; Li, Fengling; Blazer, Levi; Eram, Mohammad S.; Halabelian, Levon; Dilworth, David; Luciani, Genna M.; Lima-Fernandes, Evelyne; Wu, Qin; Loppnau, Peter; Palmer, Nathan; Talib, S. Zakiah A.; Brown, Peter J.; Schapira, Matthieu; Kaldis, Philipp; O'Hagan, Ronan C.; Guccione, Ernesto; Barsyte-Lovejoy, Dalia; Arrowsmith, Cheryl H.; Sanders, John M.; Kattar, Solomon D.; Bennett, D. Jonathan; Nicholson, Benjamin; Vedadi, Masoud 分享 收藏 分享 收藏 Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3Boettcher, Jark; Dilworth, David; Reiser, Ulrich; Neumueller, Ralph A.; Schleicher, Michael; Petronczki, Mark; Zeeb, Markus; Mischerikow, Nikolai; Allali-Hassani, Abdellah; Szewczyk, Magdalena M.; Li, Fengling; Kennedy, Steven; Vedadi, Masoud; Barsyte-Lovejoy, Dalia; Brown, Peter J.; Huber, Kilian V. M.; Rogers, Catherine M.; Wells, Carrow, I; Fedorov, Oleg; Rumpel, Klaus; Zoephel, Andreas; Mayer, Moriz; Wunberg, Tobias; Boese, Dietrich; Zahn, Stephan; Arnhof, Heribert; Berger, Helmut; Reiser, Christoph; Hoermann, Alexandra; Krammer, Teresa; Corcokovic, Maja; Sharps, Bernadette; Winkler, Sandra; Haering, Daniela; Cockcroft, Xiao-Ling; Fuchs, Julian E.; Muellauer, Barbara; Weiss-Puxbaum, Alexander; Gerstberger, Thomas; Boehmelt, Guido; Vakoc, Christopher R.; Arrowsmith, Cheryl H.; Pearson, Mark; McConnell, Darryl B. 分享 收藏 Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1)Xiong, Yan; Greschik, Holger; Johansson, Catrine; Seifert, Ludwig; Bacher, Johannes; Park, Kwang-su; Babault, Nicolas; Martini, Michael; Fagan, Vincent; Li, Fengling; Chau, Irene; Christott, Thomas; Dilworth, David; Barsyte-Lovejoy, Dalia; Vedadi, Masoud; Arrowsmith, Cheryl H.; Brennan, Paul; Fedorov, Oleg; Jung, Manfred; Farnie, Gillian; Liu, Jing; Oppermann, Udo; Schuele, Roland; Jin, Jian 分享 收藏 分享 收藏 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification (vol 8, 13658, 2018Kalinin, Alexandr A.; Allyn-Feuer, Ari; Ade, Alex; Fon, Gordon-Victor; Meixner, Walter; Dilworth, David; Husain, Syed S.; de Wet, Jeffrey R.; Higgins, Gerald A.; Zheng, Gen; Creekmore, Amy; Wiley, John W.; Verdone, James E.; Veltri, Robert W.; Pienta, Kenneth J.; Coffey, Donald S.; Athey, Brian D.; Dinov, Ivo D. 分享 收藏 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification用于细胞核形态分析和分类的三维形状建模Kalinin, Alexandr A.; Allyn-Feuer, Ari; Ade, Alex; Fon, Gordon-Victor; Meixner, Walter; Dilworth, David; Husain, Syed S.; de Wett, Jeffrey R.; Higgins, Gerald A.; Zheng, Gen; Creekmore, Amy; Wiley, John W.; Verdone, James E.; Veltri, Robert W.; Pienta, Kenneth J.; Coffey, Donald S.; Athey, Brian D.; Dinov, Ivo D. 分享 收藏 The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stabilityDilworth, David; Gudavicius, Geoff; Xu, Xiaoxue; Boyce, Andrew K. J.; O'Sullivan, Connor; Serpa, Jason J.; Bilenky, Misha; Petrochenko, Evgeniy V.; Borchers, Christoph H.; Hirst, Martin; Swayne, Leigh Anne; Howard, Perry; Nelson, Christopher J. 分享 收藏 The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding moduleDilworth, David; Upadhyay, Santosh K.; Bonnafous, Pierre; Edoo, Amiirah Bibi; Bourbigot, Sarah; Pesek-Jardim, Francy; Gudavicius, Geoff; Serpa, Jason J.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Nelson, Christopher J.; Mackereth, Cameron D. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
