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J

James M. Rae

ruhr university bochum

48H指数
294论文数
1.1W被引数
收录论文 97
发表时间
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Targeting monopolar spindle kinase I (Mps1 or TTK) induces radiosensitization in syngeneic models of triple negative breast cancer (TNBC) and potentiates type I interferon (T1IFN) signaling靶向单极纺锤体激酶I (Mps1或TTK)在自体同源的三阴性乳腺癌(TNBC)模型中诱导放射增敏并增强I型干扰素(T1IFN)信号传导
errNeoplasia
IF7.7
err2025-06-09
err0
PREAI
errKassidy M. Jungles; Caroline R. Bishop; Cydnee M. Wilson; Meilan Liu; Kalli R. Jungles; Kari Wilder-Romans; Corey W. Speers; Lori J. Pierce; James M. Rae
err分享
err收藏
Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-25
err0
PREAI
errRej, Rohan Kalyan; Hu, Biao; Chen, Zhixiang; Acharyya, Ranjan Kumar; Wu, Dimin; Metwally, Hoda; Mceachern, Donna; Wang, Yu; Jiang, Wei; Bai, Longchuan; Nishimura, Leticia S.; Gersch, Christina L.; Wang, Meilin; Wen, Bo; Sun, Duxin; Carlson, Kathryn; Katzenellenbogen, John A.; Xu, Guozhang; Zhang, Weihong; Wu, Wenxue; Priestley, E. Scott; Sui, Zhihua; Rae, James M.; Wang, Shaomeng
err分享
err收藏
Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER plus Human Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-01
err0
PREAI
errAcharyya, Ranjan Kumar; Rej, Rohan Kalyan; Hu, Biao; Chen, Zhixiang; Wu, Dimin; Lu, Jianfeng; Metwally, Hoda; Mceachern, Donna; Wang, Yu; Jiang, Wei; Bai, Longchuan; Tosovic, Jelena; Gersch, Christina L.; Xu, Guozhang; Zhang, Weihong; Wu, Wenxue; Priestley, E. Scott; Sui, Zhihua; Sarkari, Farzad; Wen, Bo; Sun, Duxin; Rae, James M.; Wang, Shaomeng
err分享
err收藏
Targeting aurora kinase B (AURKB) as a radiosensitizing strategy in syngeneic models of triple negative breast cancer ( TNBC)
errCANCER RESEARCH
IF16.6
err2024-03-22
err1
PREAI
errJungles, Kassidy M.; Wang, Zhuwen; Bishop, Caroline; Wilson, Cydnee; Liu, Meilan; James, Jadyn; Green, Michael; Rae, James M.; Speers, Corey W.; Pierce, Lori J.
err分享
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Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-30
err13
errOAAI
errChen, Zhixiang; Hu, Biao; Rej, Rohan Kalyan; Wu, Dimin; Acharyya, Ranjan Kumar; Wang, Mingliang; Xu, Tianfeng; Lu, Jianfeng; Metwally, Hoda; Wang, Yu; Mceachern, Donna; Bai, Longchuan; Gersch, Christina L.; Wang, Meilin; Zhang, Wenjing; Li, Qiuxia; Wen, Bo; Sun, Duxin; Rae, James M.; Wang, Shaomeng
err分享
err收藏
Targeting the Estrogen Receptor for the Treatment of Breast Cancer: Recent Advances and Challenges
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-06-28
err34
errOAAI
errRej, Rohan Kalyan; Thomas II, Junius Eugene; Acharyya, Ranjan Kumar; Rae, James Michael; Wang, Shaomeng
err分享
err收藏
Targeting monopolar spindle kinase I (TTK) as a radiosensitizing strategy in syngeneic murine models of triple negative breast cancer (TNBC) and its implications on the tumor immune microenvironment
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errJungles, Kassidy M.; Wang, Zhuwen; Bishop, Caroline R.; Jungles, Kalli R.; Wilson, Cydnee; Liu, Meilan; Pearson, Ashley N.; Holcomb, Erin A.; Chandler, Ben; James, Jadyn; Huber, Amanda; Pierce, Lori J.; Speers, Corey; Rae, James M.; Green, Michael D.
err分享
err收藏
Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errCani, Andi K.; Dolce, Emily M.; Hu, Kevin; Liu, Chia-Jen; Darga, Elizabeth P.; Robinson, Dan; Wu, Yi-Mi; Thomas, Dafydd G.; Paoletti, Costanza; Tomlins, Scott A.; Rae, James M.; Udager, Aaron M.; Chinnaiyan, Arul M.; Cobain, Erin F.; Hayes, Daniel F.
err分享
err收藏
Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer
errBRITISH JOURNAL OF CANCER
IF6.8
err2022-05-26
err4
errOAAI
errMichmerhuizen, Anna R.; Lerner, Lynn M.; Ward, Connor; Pesch, Andrea M.; Zhang, Amanda; Schwartz, Rachel; Wilder-Romans, Kari; Eisner, Joel R.; Rae, James M.; Pierce, Lori J.; Speers, Corey W.
err分享
err收藏
Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models (vol 8, 31, 2022)
errNPJ BREAST CANCER
IF7.6
err2022-04-20
err0
errOAAI
errMichmerhuizen, Anna R.; Lerner, Lynn M.; Pesch, Andrea M.; Ward, Connor; Schwartz, Rachel; Wilder-Romans, Kari; Liu, Meilan; Nino, Charles; Jungles, Kassidy; Azaria, Ruth; Jelley, Alexa; Zambrana Garcia, Nicole; Harold, Alexis; Zhang, Amanda; Wharram, Bryan; Hayes, Daniel F.; Rae, James M.; Pierce, Lori J.; Speers, Corey W.
err分享
err收藏
Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models
errNPJ BREAST CANCER
IF7.6
err2022-03-10
err12
errOAAI
errMichmerhuizen, Anna R.; Lerner, Lynn M.; Pesch, Andrea M.; Ward, Connor; Schwartz, Rachel; Wilder-Romans, Kari; Liu, Meilan; Nino, Charles; Jungles, Kassidy; Azaria, Ruth; Jelley, Alexa; Garcia, Nicole Zambrana; Harold, Alexis; Zhang, Amanda; Wharram, Bryan; Hayes, Daniel F.; Rae, James M.; Pierce, Lori J.; Speers, Corey W.
err分享
err收藏
Endocrine therapy treatment radiosensitizes estrogen receptor-positive breast cancers
errCANCER RESEARCH
IF16.6
err2022-02-15
err0
PREAI
errMichmerhuizen, Anna R.; Lerner, Lynn; Pesch, Andrea M.; Ward, Connor; Schwartz, Rachel; Wilder-Romans, Kari; Liu, Meilan; Wharram, Bryan; Harold, Alexis; Azaria, Ruth; Garcia, Nicole Zambrana; Hayes, Daniel F.; Rae, James M.; Pierce, Lori J.; Speers, Corey W.
err分享
err收藏
Evaluation of the predicted sensitivity to endocrine therapy (SET2,3 index) and the 21-gene Breast Recurrence Score® assay in node-positive postmenopausal breast cancer: Results from an analysis in the SWOG S8814 trial
errCANCER RESEARCH
IF16.6
err2022-02-15
err0
PREAI
errSpeers, Corey W.; Symmans, W. Fraser; Barlow, William E.; Trevarton, Alex; The, Stephanie; Du, Lili; Rae, James M.; Shak, Steven; Baehner, Frederick L.; Sharma, Priyanka; Pusztai, Lajos; Hortobagyi, Gabriel N.; Hayes, Daneil F.; Albain, Kathy S.; Godwin, Andrew; Thompson, Alastair
err分享
err收藏
RB expression confers sensitivity to CDK4/6 inhibitor-mediated radiosensitization across breast cancer subtypes
errJCI INSIGHT
IF6.1
err2022-02-08
err14
errOAAI
errPesch, Andrea M.; Hirsh, Nicole H.; Michmerhuizen, Anna R.; Jungles, Kassidy M.; Wilder-Romans, Kari; Chandler, Benjamin C.; Liu, Meilan; Lerner, Lynn M.; Nino, Charles A.; Ward, Connor; Cobain, Erin F.; Lawrence, Theodore S.; Pierce, Lori J.; Rae, James M.; Speers, Corey W.
err分享
err收藏
Impact of Pharmacogenetics on Intravenous Tacrolimus Exposure and Conversions to Oral Therapy
errTRANSPLANTATION AND CELLULAR THERAPY
IF4.4
err2022-01-01
err9
errOAAI
errPasternak, Amy L.; Marcath, Lauren A.; Li, Yajing; Nguyen, Vy; Gersch, Christina L.; Rae, James M.; Frame, David; Scappaticci, Gianni; Kidwell, Kelley M.; Hertz, Daniel L.
err分享
err收藏
The role of estrogen receptor signaling in suppressing the immune response to cancer COMMENT
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2021-12-15
err10
errOAAI
errRae, James M.; Lippman, Marc E.
err分享
err收藏
CDK4/6 inhibitor-mediatated radiosensitization of estrogen receptor positive breast cancer
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errPesch, Andrea M.; Hirsh, Nicole; Chandler, Benjamin C.; Michmerhuizen, Anna R.; Ritter, Cassandra L.; Androsiglio, Marlie; Wilder-Romans, Kari; Liu, Meilan; Gersch, Christina L.; Larios, Jose M.; Rae, James M.; Speers, Corey W.
err分享
err收藏
Targeted degradation of activating estrogen receptor α ligand-binding domain mutations in human breast cancer (vol 15, pg 854, 2019)
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2020-03-16
err1
errOAAI
errGonzalez, Thomas L.; Hancock, Molly; Sun, Siqi; Gersch, Christina L.; Larios, Jose M.; David, Wadie; Hu, Jiantao; Hayes, Daniel F.; Wang, Shaomeng; Rae, James M.
err分享
err收藏
Targeted degradation of activating estrogen receptor α ligand-binding domain mutations in human breast cancer乳腺癌中激活雌激素受体 α 配体结合域突变的靶向降解
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2020-02-17
err51
PREAI
errGonzalez, Thomas L.; Hancock, Molly; Sun, Siqi; Gersch, Christina L.; Larios, Jose M.; David, Waddie; Hu, Jiantao; Hayes, Daniel F.; Wang, Shaomeng; Rae, James M.
err分享
err收藏
Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor Antagonist, Radiosensitizes AR-Positive Triple Negative Breast Cancer Cells
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2020-02-11
err28
errOAAI
errMichmerhuizen, Anna R.; Chandler, Benjamin; Olsen, Eric; Wilder-Romans, Kari; Moubadder, Leah; Liu, Meilan; Pesch, Andrea M.; Zhang, Amanda; Ritter, Cassandra; Ward, S. Tanner; Santola, Alyssa; Nyati, Shyam; Rae, James M.; Hayes, Daniel; Feng, Felix Y.; Spratt, Daniel; Wahl, Daniel; Eisner, Joel; Pierce, Lori J.; Speers, Corey
err分享
err收藏

研究方向

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合作学者
合作期刊
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Gabriel N. Hortobágyi
H 指数: 187 · 论文数: 1.9K
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Giuseppe Viale
H 指数: 157 · 论文数: 1.3K
J
Jorge S. Reis‐Filho
H 指数: 153 · 论文数: 1.5K
M
Mitch Dowsett
H 指数: 147 · 论文数: 1.6K
A
Arul M. Chinnaiyan
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