Michael D. Johnson - Publications, H-index & Citations

Michael D. Johnson

department of oncology

64H指数

305论文数

1.6W被引数

收录论文 80

发表时间

Matriptase proteolysis selectively drives disassembly and internalization of the claudin-7 complex while preserving E-cadherin 基质溶酶蛋白水解选择性驱动紧密连接蛋白7复合物的解聚和内化，同时保留E-钙黏蛋白

Human Cell

IF3.1

2026-07-13

PREAI

Yu-Ling A. Kao; He-Yu Huang; Yin S. Yu; Nanxi Huang; Ya-Chin Chan; Chen-Ray Lee; Michael D. Johnson; Chen-Yong Lin

Dynamic modulation of intercellular adhesion mediated by matriptase-EPCAM/Trop-2 axes is critical for cell extrusion, division, and collective migration 基质溶酶-EPCAM/Trop-2轴动态调控的细胞间粘附对细胞外排、分裂和集体迁移至关重要

Cell Adhesion & Migration

IF3.5

2026-05-05

OAAI

Yu-Ling A. Kao; Qiaochu Wang; Dajun D. Lu; Shigeki Umemura; Vivien Lee; Ying Hsuan Tsai; Robert B. Barndt; Jehng‑Kang Wang; Michael D. Johnson; Chen-Yong Lin

C-terminally phosphorylated p27 activates self-renewal driver genes to program cancer stem cell expansion, mammary hyperplasia and cancer

NATURE COMMUNICATIONS

IF15.7

2024-06-17

OAAI

Razavipour, Seyedeh Fatemeh; Yoon, Hyunho; Jang, Kibeom; Kim, Minsoon; Nawara, Hend M.; Bagheri, Amir; Huang, Wei-Chi; Shin, Miyoung; Zhao, Dekuang; Zhou, Zhiqun; Van Boven, Derek; Briegel, Karoline; Morey, Lluis; Ince, Tan A.; Johnson, Michael; Slingerland, Joyce M.

SPINT2 mutations in the Kunitz domain 2 found in SCSD patients inactivate HAI-2 as prostasin inhibitor via abnormal protein folding and N-glycosylation

HUMAN MOLECULAR GENETICS

IF3.2

2024-01-25

PREAI

Huang, Nanxi; Wang, Qiaochu; Bernard, Robert B.; Chen, Chao-Yang; Hu, Je-Ming; Wang, Jehng-Kang; Chan, Khee-Siang; Johnson, Michael D.; Lin, Chen-Yong

HAI-1 is required for the novel role of FGFBP1 in maintenance of cell morphology and F-actin rearrangement in human keratinocytes

HUMAN CELL

IF3.1

2023-04-19

PREAI

Lu, Dajun D.; Huang, Nanxi; Li, Sheng-Wen A.; Fang, Jessica R.; Lai, Chih-Hsin; Wang, Jehng-Kang; Chan, Khee-Siang; Johnson, Michael D.; Lin, Chen-Yong

N-glycosylation on Asn-57 is required for the correct HAI-2 protein folding and protease inhibitory activity

GLYCOBIOLOGY

IF3.3

2023-01-13

OAAI

Huang, Nanxi; Wang, Qiaochu; Chen, Chao-Yang; Hu, Je-Ming; Wang, Jehng-Kang; Chang, Ping-Ying; Johnson, Michael D.; Lin, Chen-Yong

Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity

GENES & DISEASES

IF9.4

2022-07-01

OAAI

Chiu, Yi-Lin; Wu, Yi-Ying; Barndt, Robert B.; Lin, Yu-Wen; Sytwo, Hou-Ping; Cheng, Amy; Yang, Kacy; Chan, Khee-Siang; Wang, Jehng-Kang; Johnson, Michael D.; Lin, Chen-Yong

The difference in the intracellular Arg/Lys-rich and EHLVY motifs contributes to distinct subcellular distribution of HAI-1 versus HAI-2

HUMAN CELL

IF3.1

2021-10-13

PREAI

Huang, Nanxi; Barndt, Robert B.; Lu, Dajun D.; Wang, Qiaochu; Huang, Shih-Ming; Wang, Jehng-Kang; Chang, Ping-Ying; Chen, Chao-Yang; Hu, Je-Ming; Su, Hui-Chen; Johnson, Michael D.; Lin, Chen-Yong

Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells

HUMAN MOLECULAR GENETICS

IF3.2

2021-06-04

OAAI

Barndt, Robert B.; Lee, Mon-Juan; Huang, Nanxi; Lu, Dajun D.; Lee, See-Chi; Du, Po-Wen; Chang, Chun-Chia; Tsai, Ping-Feng B.; Huang, Yu-Siou K.; Chang, Hao-Ming; Wang, Jehng-Kang; Lai, Chih-Hsin; Johnson, Michael D.; Lin, Chen-Yong

Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes

HUMAN CELL

IF3.1

2021-01-24

PREAI

Lu, Dajun D.; Gu, Yayun; Li, Sheng-Wen A.; Barndt, Robert J.; Huang, Shih-Ming; Wang, Jehng-Kang; Su, Hui Chen; Johnson, Michael D.; Lin, Chen-Yong

Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation

HUMAN CELL

IF3.1

2020-08-10

PREAI

Jia, Bailing; Thompson, Hamishi A.; Barndt, Robert B.; Chiu, Yi-Lin; Lee, Mon-Juan; Lee, See-Chi; Wang, Jehng-Kang; Tang, Hung-Jen; Lin, Chen-Yong; Johnson, Michael D.

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin

HUMAN CELL

IF3.1

2020-07-02

PREAI

Chang, Shun-Cheng; Chiang, Chien-Ping; Lai, Chih-Hsin; Du, Po-Wen A.; Hung, Yu-Sin; Chen, Yu-Hsuan; Yang, Hui-Yu; Fang, Hao-Yu; Lee, Shiao-Pieng; Tang, Hung-Jen; Wang, Jehng-Kang; Johnson, Michael D.; Lin, Chen-Yong

The spatiotemporal control of human matriptase action on its physiological substrates: a case against a direct role for matriptase proteolytic activity in profilaggrin processing and desquamation

HUMAN CELL

IF3.1

2020-04-18

PREAI

Lin, Chen-Yong; Wang, Jehng-Kang; Johnson, Michael D.

Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2019-02-19

OAAI

Chiu, Yi-Lin; Wu, Yi-Ying; Barndt, Robert B.; Yeo, Yee Hui; Lin, Yu-Wen; Sytwo, Hou-Ping; Liu, Huan-Cheng; Xu, Yuan; Jia, Bailing; Wang, Jehng-Kang; Johnson, Michael D.; Lin, Chen-Yong

Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines

TOXICOLOGICAL SCIENCES

IF4.1

2018-04-07

OAAI

Gonzalez, Thomas L.; Moos, Rebecca K.; Gersch, Christina L.; Johnson, Michael D.; Richardson, Rudy J.; Koch, Holger M.; Rae, James M.

Cadmium removal from aqueous solution by low-cost native and surface modified Sorghum x drummondii (Sudangrass)

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING

IF7.2

2018-04-01

OAAI

Saraeian, Alireza; Hadi, Atefe; Raji, Foad; Ghassemi, Abbas; Johnson, Michael

Spectroscopic methods for aqueous cyclodextrin inclusion complex binding measurement for 1,4-dioxane, chlorinated co-contaminants, and ozone

JOURNAL OF CONTAMINANT HYDROLOGY

IF4.4

2018-03-01

OAAI

Khan, Naima A.; Johnson, Michael D.; Carroll, Kenneth C.

Comprehensive Mutation and Copy Number Profiling in Archived Circulating Breast Cancer Tumor Cells Documents Heterogeneous Resistance Mechanisms

CANCER RESEARCH

IF16.6

2018-02-14

OAAI

Paoletti, Costanza; Cani, Andi K.; Larios, Jose M.; Hovelson, Daniel H.; Aung, Kimberly; Darga, Elizabeth P.; Cannell, Emily M.; Baratta, Paul J.; Liu, Chia-Jen; Chu, David; Yazdani, Maryam; Blevins, Allen R.; Sero, Valeria; Tokudome, Nahomi; Thomas, Dafydd G.; Gersch, Christina; Schott, Anne F.; Wu, Yi-Mi; Lonigro, Robert; Robinson, Dan R.; Chinnaiyan, Arul M.; Bischoff, Farideh Z.; Johnson, Michael D.; Park, Ben H.; Hayes, Daniel F.; Rae, James M.; Tomlins, Scott A.

SELECTIVE INHIBITION OF PROSTASIN IN HUMAN ENTEROCYTES BY THE INTEGRAL MEMBRANE KUNITZ-TYPE SERINE PROTEASE INHIBITOR HAI-2

GASTROENTEROLOGY

IF25.1

2017-04-01

PREAI

Yeo, Yee Hui; Shiao, Frank; Liu, Li-Ching O.; Huang, Nanxi; Lai, Ying-Jung J.; Barndt, Robert J.; Tseng, Chun-Che; Wang, Jehng-Kang; Jia, Bailing; Johnson, Michael D.; Lin, Chen-Yong

Endocrine Response Phenotypes Are Altered by Charcoal-Stripped Serum Variability

ENDOCRINOLOGY

IF3.3

2016-10-01

OAAI

Sikora, Matthew J.; Johnson, Michael D.; Lee, Adrian V.; Oesterreich, Steffi

研究方向