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Stephen C. Blacklow

harvard medical school

73H指数
291论文数
2.2W被引数
收录论文 92
发表时间
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β-arrestin recruitment facilitates a direct association with G proteinsβ-arrestin招募促进与G蛋白的直接结合
errNature Communications
IF15.7
err2026-07-17
err0
errOAAI
errClaudia Y. Lee; Jeffrey S. Smith; Taylor Kohlmann; Emily M. Meara; Uyen Pham; Frank Kwarcinski; Andrew N. Dates; Jessica K. Orofino; Issac Choi; Ari S. Hilibrand; Chanpreet Jassal; Abigail Gilmer; Stephen C. Blacklow; Gregory G. Tall; Andrew C. Kruse; Sudarshan Rajagopal
err分享
err收藏
Adhesion G protein-coupled receptors粘附g蛋白偶联受体
errPharmacological Reviews
IF17.3
err2026-01-16
err0
errOAAI
errTobias Langenhan; Garret R. Anderson; Demet Araç; Gabriela Aust; Monserrat Avila-Zozaya; Sofie Morsing Bagger; Patrick Barth; Sandra Berndt; Stephen C. Blacklow; Beatriz Blanco-Redondo; Antony A. Boucard; James Bridges; Lara-Sophie Brodmerkel; Kathleen M. Caron; Yin Kwan Chung; Andrew N. Dates; Virginea de Araujo Farias; Daniel Del Toro; Joseph G. Duman; Felix B. Engel
err分享
err收藏
Design of soluble Notch agonists that drive T cell development and boost immunity可溶性Notch激动剂的设计：驱动T细胞发育并增强免疫力
errCell
IF42.5
err2025-08-01
err0
PREAI
errRubul Mout; Ran Jing; Mayuri Tanaka-Yano; Emily D. Egan; Helen Eisenach; Martin A. Kononov; Roland Windisch; Mohamad Ali Toufic Najia; Allison Tompkins; Luca Hensch; Trevor Bingham; Rajesh Gunage; Yunliang Zhao; Natasha I. Edman; Christopher Li; Dahai Wang; Thorsten M. Schlaeger; Leonard I. Zon; Trista E. North; Urban Lendahl; R. Grant Rowe; David Baker; Stephen C. Blacklow; George Q. Daley
err分享
err收藏
Molecular mechanism of PP2A/B55α phosphatase inhibition by IER5IER5对PP2A/B55α磷酸酶的分子抑制机制
errCELL CHEMICAL BIOLOGY
IF7.2
err2025-04-01
err0
PREAI
errCao, Ruili; Jones, Daniel T. D.; Pan, Li; Yang, Annie; Wang, Shumei; Padi, Sathish K. R.; Rawson, Shaun; Aster, Jon C.; Blacklow, Stephen C.
err分享
err收藏
Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors粘附g蛋白偶联受体中束缚激动剂信号的异质性
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-08-01
err4
PREAI
errDates, Andrew N.; Jones, Daniel T. D.; Smith, Jeffrey S.; Skiba, Meredith A.; Rich, Maria F.; Burruss, Maggie M.; Kruse, Andrew C.; Blacklow, Stephen C.
err分享
err收藏
A spatiotemporal map of co-receptor signaling networks underlying B cell activation
errCELL REPORTS
IF6.9
err2024-06-01
err1
errOAAI
errSusa, Katherine J.; Bradshaw, Gary A.; Eisert, Robyn J.; Schilling, Charlotte M.; Kalocsay, Marian; Blacklow, Stephen C.; Kruse, Andrew C.
err分享
err收藏
Tetraspanins: structure, dynamics, and principles of partner-protein recognition
errTRENDS IN CELL BIOLOGY
IF18.1
err2024-06-01
err10
PREAI
errSusa, Katherine J.; Kruse, Andrew C.; Blacklow, Stephen C.
err分享
err收藏
Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
errDEVELOPMENTAL CELL
IF8.7
err2024-06-01
err0
PREAI
errTveriakhina, Lena; Scanavachi, Gustavo; Egan, Emily D.; Correia, Ricardo Bango Da Cunha; Martin, Alexandre P.; Rogers, Julia M.; Yodh, Jeremy S.; Aster, Jon C.; Kirchhausen, Tom; Blacklow, Stephen C.
err分享
err收藏
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues
errNATURE COMMUNICATIONS
IF15.7
err2024-04-10
err0
errOAAI
errKock, Kian Hong; Kimes, Patrick K.; Gisselbrecht, Stephen S.; Inukai, Sachi; Phanor, Sabrina K.; Anderson, James T.; Ramakrishnan, Gayatri; Lipper, Colin H.; Song, Dongyuan; Kurland, Jesse V.; Rogers, Julia M.; Jeong, Raehoon; Blacklow, Stephen C.; Irizarry, Rafael A.; Bulyk, Martha L.
err分享
err收藏
A spatiotemporal Notch interaction map from plasma membrane to nucleus
errSCIENCE SIGNALING
IF6.6
err2023-08-01
err3
errOAAI
errMartin, Alexandre P. P.; Bradshaw, Gary A. A.; Eisert, Robyn J. J.; Egan, Emily D. D.; Tveriakhina, Lena; Rogers, Julia M. M.; Dates, Andrew N. N.; Scanavachi, Gustavo; Aster, Jon C. C.; Kirchhausen, Tom; Kalocsay, Marian; Blacklow, Stephen C. C.
err分享
err收藏
Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve
errJAMA CARDIOLOGY
IF14.1
err2023-08-01
err15
errOAAI
errTessler, Idit; Albuisson, Juliette; Pineiro-Sabaris, Rebeca; Verstraeten, Aline; Kaya, Hatem Elif Kamber; Siguero-Alvarez, Marcos; Goudot, Guillaume; MacGrogan, Donal; Luyckx, Ilse; Shpitzen, Shoshana; Levin, Galina; Kelman, Guy; Reshef, Noga; Mananet, Hugo; Holdcraft, Jake; Muehlschlegel, Jochen D.; Peloso, Gina M.; Oppenheim, Olya; Cheng, Charles; Mazzella, Jean-Michael; Andelfinger, Gregor; Mital, Seema; Eriksson, Per; Billon, Clarisse; Heydarpour, Mahyar; Dietz, Harry C.; Jeunemaitre, Xavier; Leitersdorf, Eran; Sprinzak, David; Blacklow, Stephen C.; Body, Simon C.; Carmi, Shai; Loeys, Bart; de la Pompa, Jose Luis; Gilon, Dan; Messas, Emmanuel; Durst, Ronen
err分享
err收藏
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling
errNATURE COMMUNICATIONS
IF15.7
err2023-04-29
err4
errOAAI
errJones, Daniel T. D.; Dates, AndrewN.; Rawson, Shaun D.; Burruss, Maggie M.; Lipper, Colin H.; Blacklow, Stephen C.
err分享
err收藏
Calcium depletion dissociates and activates heterodimeric notch receptors
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err440
errOAAI
errRand, MD; Grimm, LM; Artavanis-Tsakonas, S; Patriub, V; Blacklow, SC; Sklar, J; Aster, JC
err分享
err收藏
Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1鉴定影响NOTCH1致白血病活性的保守负调控序列
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err94
errOAAI
errChiang, Mark Y.; Xu, Mina L.; Histen, Gavin; Shestova, Olga; Roy, Monideepa; Nam, Yunsun; Blacklow, Stephen C.; Sacks, David B.; Pear, Warren S.; Aster, Jon C.
err分享
err收藏
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err415
errOAAI
errWeng, AP; Nam, Y; Wolfe, MS; Pear, WNS; Griffin, JD; Blacklow, SC; Aster, JC
err分享
err收藏
Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err269
errOAAI
errMalecki, Michael J.; Sanchez-Irizarry, Cheryll; Mitchell, Jennifer L.; Histen, Gavin; Xu, Mina L.; Aster, Jon C.; Blacklow, Stephen C.
err分享
err收藏
Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err235
errOAAI
errSanchez-Irizarry, C; Carpenter, AC; Weng, AP; Pear, WS; Aster, JC; Blacklow, SC
err分享
err收藏
MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err7
errOAAI
errRogers, Julia M.; Guo, Bingqian; Egan, Emily D.; Aster, Jon C.; Adelman, Karen; Blacklow, Stephen C.
err分享
err收藏
Functional Comparison between Endogenous and Synthetic Notch Systems
errACS SYNTHETIC BIOLOGY
IF3.9
err2022-09-15
err11
errOAAI
errKhamaisi, Bassma; Luca, Vincent C.; Blacklow, Stephen C.; Sprinzak, David
err分享
err收藏
Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling
errNATURE CHEMICAL BIOLOGY
IF13.7
err2022-09-01
err6
errOAAI
errGonzalez-Perez, David; Das, Satyajit; Antfolk, Daniel; Ahsan, Hadia S.; Medina, Elliot; Dundes, Carolyn E.; Jokhai, Rayyan T. T.; Egan, Emily D. D.; Blacklow, Stephen C. C.; Loh, Kyle M. M.; Rodriguez, Paulo C. C.; Luca, Vincent C. C.
err分享
err收藏

研究方向

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