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Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation 严重和危重COVID-19患者的转录组学分析揭示了表达、剪接和聚腺苷酸化方面的改变 Labrecque, Marjorie; Brunet-Ratnasingham, Elsa; Hamilton, Laura K.; Auld, Daniel; Montpetit, Alexandre; Richards, Brent; Durand, Madeleine; Rousseau, Simon; Finzi, Andres; Kaufmann, Daniel E.; Tetreault, Martine 分享 收藏
Contribution of intact viral genomes persisting in blood and tissues during ART to plasma viral rebound in SHIV-infected rhesus macaques 在ART治疗期间，持续存在于血液和组织中的完整病毒基因组对SHIV感染恒河猴血浆病毒反弹的贡献 Trifone, Cesar; Richard, Corentin; Pagliuzza, Amelie; Dufour, Caroline; Lemieux, Audree; Clark, Natasha M.; Janaka, Sanath K.; Fennessey, Christine M.; Keele, Brandon E.; Fromentin, Remi; Estes, Jacob D.; Kaufmann, Daniel E.; Finzi, Andres; Evans, David T.; Chomont, Nicolas 分享 收藏
Distinct peripheral pro-inflammatory profile associated with tuberous sclerosis complex and epilepsy 与结节性硬化症和癫痫相关的不同外周促炎特征 Balthazard, Renaud; Drouin-Engler, Rose-Marie; Bertrand, Samuel; Zine-Eddine, Faycal; Li, Jimmy; Tastet, Olivier; Daigneault, Audrey; Mamane, Victoria H.; Ortega-Delgado, Gloria Gabrielle; Flores, Alina Maria Sreng; Kaufmann, Daniel E.; Major, Philippe; House, Andrew A.; Letourneau-Guillon, Laurent; Arbour, Nathalie; Keezer, Mark R.; Larochelle, Catherine 分享 收藏
CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies Richard, Jonathan; Sannier, Geremy; Zhu, Li; Prevost, Jeremie; Marchitto, Lorie; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Kim, Hongil; Sun, Yaping; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Delgado, Gloria-Gabrielle; Dube, Mathieu; Kirchhoff, Frank; Hahn, Beatrice H.; Kumar, Priti; Kaufmann, Daniel E.; Finzi, Andres 分享 收藏
Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity 持续的IFN信号传导与SARS-CoV-2-specific免疫的延迟发展有关 Brunet-Ratnasingham, Elsa; Morin, Sacha; Randolph, Haley E.; Labrecque, Marjorie; Belair, Justin; Lima-Barbosa, Raphael; Pagliuzza, Amelie; Marchitto, Lorie; Hultstrom, Michael; Niessl, Julia; Cloutier, Rose; Flores, Alina M. Sreng; Brassard, Nathalie; Benlarbi, Mehdi; Prevost, Jeremie; Ding, Shilei; Anand, Sai Priya; Sannier, Geremy; Marks, Amanda; Wagsaeter, Dick; Bareke, Eric; Zeberg, Hugo; Lipcsey, Miklos; Frithiof, Robert; Larsson, Anders; Zhou, Sirui; Nakanishi, Tomoko; Morrison, David; Vezina, Dani; Bourassa, Catherine; Gendron-Lepage, Gabrielle; Medjahed, Halima; Point, Floriane; Richard, Jonathan; Larochelle, Catherine; Prat, Alexandre; Cunningham, Janet L.; Arbour, Nathalie; Durand, Madeleine; Richards, J. Brent; Moon, Kevin; Chomont, Nicolas; Finzi, Andres; Tetreault, Martine; Barreiro, Luis; Wolf, Guy; Kaufmann, Daniel E. 分享 收藏
Intra-Host Evolution Analyses in an Immunosuppressed Patient Supports SARS-CoV-2 Viral Reservoir Hypothesis Fournelle, Dominique; Mostefai, Fatima; Brunet-Ratnasingham, Elsa; Poujol, Raphael; Grenier, Jean-Christophe; Galvez, Jose Hector; Pagliuzza, Amelie; Levade, Ines; Moreira, Sandrine; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Gendron-Lepage, Gabrielle; Bourassa, Catherine; Tauzin, Alexandra; Grandjean Lapierre, Simon; Chomont, Nicolas; Finzi, Andres; Kaufmann, Daniel E.; Craig, Morgan; Hussin, Julie G. 分享 收藏
Enhanced detection of antigen-specific T cells by a multiplexed AIM assay Lemieux, Audree; Sannier, Geremy; Nicolas, Alexandre; Nayrac, Manon; Delgado, Gloria -Gabrielle; Cloutier, Rose; Brassard, Nathalie; Laporte, Melanie; Duchesne, Melina; Flores, Alina Maria Sreng; Finzi, Andres; Tastet, Olivier; Dube, Mathieu; Kaufmann, Daniel E. 分享 收藏
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia Benlarbi, Mehdi; Richard, Jonathan; Bourassa, Catherine; Tolbert, William D.; Chartrand-Lefebvre, Carl; Gendron-Lepage, Gabrielle; Sylla, Mohamed; El-Far, Mohamed; Messier-Peet, Marc; Guertin, Camille; Turcotte, Isabelle; Fromentin, Remi; Verly, Myriam Maude; Prevost, Jeremie; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Maldarelli, Frank; Chomont, Nicolas; Begin, Philippe; Tremblay, Cecile; Baril, Jean-Guy; Trottier, Benoit; Trottier, Sylvie; Duerr, Ralf; Pazgier, Marzena; Durand, Madeleine; Finzi, Andres 分享 收藏
Humoral Responses Elicited after a Fifth Dose of SARS-CoV-2 mRNA Bivalent Vaccine Tauzin, Alexandra; Beaudoin-Bussieres, Guillaume; Benlarbi, Mehdi; Nayrac, Manon; Bo, Yuxia; Gendron-Lepage, Gabrielle; Medjahed, Halima; Perreault, Josee; Gokool, Laurie; Arlotto, Pascale; Morrisseau, Chantal; Tremblay, Cecile; Kaufmann, Daniel E.; Martel-Laferriere, Valerie; Levade, Ines; Cote, Marceline; Bazin, Renee; Finzi, Andres 分享 收藏
Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation An, Andy Yi; Baghela, Arjun; Zhang, Peter G. Y.; Blimkie, Travis M.; Gauthier, Jeff; Kaufmann, Daniel Elias; Acton, Erica; Lee, Amy H. Y.; Levesque, Roger C.; Hancock, Robert E. W. 分享 收藏
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120 Richard, Jonathan; Prevost, Jeremie; Bourassa, Catherine; Brassard, Nathalie; Boutin, Marianne; Benlarbi, Mehdi; Goyette, Guillaume; Medjahed, Halima; Gendron-Lepage, Gabrielle; Gaudette, Fleur; Chen, Hung-Ching; Tolbert, William D.; Smith, Amos B., III; Pazgier, Marzena; Dube, Mathieu; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Finzi, Andres 分享 收藏
A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+T cell profile 接受血液透析的人的第三次SARS-CoV-2 mRNA疫苗剂量克服了b细胞缺陷，但引起了倾斜的CD4 T细胞谱 Sannier, Geremy; Nicolas, Alexandre; Dube, Mathieu; Marchitto, Lorie; Nayrac, Manon; Tastet, Olivier; Chatterjee, Debashree; Tauzin, Alexandra; Lima-Barbosa, Raphael; Laporte, Melanie; Cloutier, Rose; Flores, Alina M. Sreng; Boutin, Marianne; Gong, Shang Yu; Benlarbi, Mehdi; Ding, Shilei; Bourassa, Catherine; Gendron-Lepage, Gabrielle; Medjahed, Halima; Goyette, Guillaume; Brassard, Nathalie; Delgado, Gloria-Gabrielle; Niessl, Julia; Gokool, Laurie; Morrisseau, Chantal; Arlotto, Pascale; Rios, Norka; Tremblay, Cecile; Martel-Laferriere, Valerie; Prat, Alexandre; Belair, Justin; Beaubien-Souligny, William; Goupil, Remi; Nadeau-Fredette, Annie-Claire; Lamarche, Caroline; Finzi, Andres; Suri, Rita S.; Kaufmann, Daniel E. 分享 收藏
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures Baghela, Arjun; An, Andy; Zhang, Peter; Acton, Erica; Gauthier, Jeff; Brunet-Ratnasingham, Elsa; Blimkie, Travis; Freue, Gabriela Cohen; Kaufmann, Daniel; Lee, Amy H. Y.; Levesque, Roger C.; Hancock, Robert E. W. 分享 收藏
Humoral Responses against BQ.1.1 Elicited after Breakthrough Infection and SARS-CoV-2 mRNA Vaccination Tauzin, Alexandra; Benlarbi, Mehdi; Medjahed, Halima; Gregoire, Yves; Perreault, Josee; Gendron-Lepage, Gabrielle; Gokool, Laurie; Morrisseau, Chantal; Arlotto, Pascale; Tremblay, Cecile; Kaufmann, Daniel E.; Martel-Laferriere, Valerie; Levade, Ines; Cote, Marceline; De Serres, Gaston; Bazin, Renee; Finzi, Andres 分享 收藏
Spike recognition and neutralization of SARS-CoV-2 Omicron subvariants elicited after the third dose of mRNA vaccine Tauzin, Alexandra; Nicolas, Alexandre; Ding, Shilei; Benlarbi, Mehdi; Medjahed, Halima; Chatterjee, Debashree; Dionne, Katrina; Gong, Shang Yu; Gendron-Lepage, Gabrielle; Bo, Yuxia; Perreault, Josee; Goyette, Guillaume; Gokool, Laurie; Arlotto, Pascale; Morrisseau, Chantal; Tremblay, Cecile; Martel-Laferriere, Valeri; De Serres, Gaston; Levade, Ines; Kaufmann, Daniel E.; Cote, Marceline; Bazin, Renee; Finzi, Andres 分享 收藏
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Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function HIV特异性CD4 T细胞上的免疫检查点表达及其对其阻断的反应取决于谱系和功能 Brunet-Ratnasingham, Elsa; Morou, Antigoni; Dube, Mathieu; Niessl, Julia; Baxter, Amy E.; Tastet, Olivier; Brassard, Nathalie; Ortega-Delgado, Gloria; Charlebois, Roxanne; Freeman, Gordon J.; Tremblay, Cecile; Routy, Jean-Pierre; Kaufmann, Daniel E. 分享 收藏
A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses Tauzin, Alexandra; Gong, Shang Yu; Chatterjee, Debashree; Ding, Shilei; Painter, Mark M.; Goel, Rishi R.; Beaudoin-Bussieres, Guillaume; Marchitto, Lorie; Boutin, Marianne; Laumaea, Annemarie; Okeny, James; Gendron-Lepage, Gabrielle; Bourassa, Catherine; Medjahed, Halima; Goyette, Guillaume; Williams, Justine C.; Bo, Yuxia; Gokool, Laurie; Morrisseau, Chantal; Arlotto, Pascale; Bazin, Renee; Fafard, Judith; Tremblay, Cecile; Kaufmann, Daniel E.; De Serres, Gaston; Richard, Jonathan; Cote, Marceline; Duerr, Ralf; Martel-Laferriere, Valerie; Greenplate, Allison R.; Wherry, E. John; Finzi, Andres 分享 收藏
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