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S

Steven Staelens

University of Antwerp
H指数:39
被引数:7,810

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In Vivo PET Imaging of [18F]CHDI-385, a Radioligand for Mutant Huntingtin Aggregates in a Mouse Model of Huntington DiseaseDisease

[18F]CHDI-385的体内PET成像，该放射性配体用于亨廷顿病小鼠模型中突变亨廷顿蛋白聚集物的检测

Journal of Nuclear Medicine
IF9.1
2026-02-010
PRE
Zajicek, Franziska; Elvas, Filipe; Miranda, Alan; Akkermans, Jordy; Verhaeghe, Jeroen; Dominguez, Celia; Doot, Robert; Khetarpal, Vinod; Bard, Jonathan; Liu, Longbin; Staelens, Steven; Bertoglio, Daniele
Imaging brain development in a KCNQ2-developmental and epileptic encephalopathy mouse model: identifying early biomarkers for functional and structural brain changes

利用KCNQ2发育性癫痫性脑病小鼠模型成像脑发育：识别功能性和结构性脑变化的早期生物标志物

eBioMedicine
IF10.8
2025-10-250
OAAI
Charissa Millevert; Nicholas Vidas-Guscic; Mohit H. Adhikari; Alan Miranda; Liesbeth Vanherp; Laurent Villard; Elisabeth Jonckers; Philippe Joye; Johan Van Audekerke; Ignace Van Spilbeeck; Els De Vriendt; Marleen Verhoye; Steven Staelens; Daniele Bertoglio; Sarah Weckhuysen
Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates

异吲哚酮类PET示踪剂用于成像突变亨廷蛋白聚集物

Journal of Medicinal Chemistry
IF6.8
2025-07-070
PRE
Longbin Liu; Peter D. Johnson; Matthew R. Mills; Penelope A. Turner; Michael E. Prime; Christopher J. Brown; Adrian Kotey; Samuel Coe; Paul R. Giles; Catherine Lloyd; Sarah Hayes; Frederic J. Marlin; Filippo Rota; Frank Herrmann; Manuela Heßmann; Sabine Schaertl; Franziska Zajicek; Stef De Lombaerde; Filipe Elvas; Jeroen Verhaeghe; Steven Staelens; Daniele Bertoglio; Xuemei Chen; Michael P. Conlon; Randall Davis; Samantha F. Ensor; James Haber; Kathryn C. Haber; Ming Min Hsai; John E. Mangette; William F. Penniman; Luca Anzillotti; Simone Esposito; Angelo Lembo; Laura Orsatti; Davide Ventre; Maria Veneziano; Christine Sandiego; Scott Haller; Gwendolyn A. Marriner; Ignacio Munoz-Sanjuan; Vinod Khetarpal; Jonathan A. Bard; Celia Dominguez
Pharmacodynamic biomarkers responsive to mutant huntingtin lowering in a Huntington's disease mouse model

对降低亨廷顿病小鼠模型中突变亨廷顿蛋白反应的药效学生物标志物

NEUROBIOLOGY OF DISEASE
IF5.6
2025-06-010
OAAI
Marchionini, Deanna M.; De Lombaerde, Stef; van Rijswijk, Joelle; Zajicek, Franziska; Everix, Liesbeth; Miranda, Alan; Aaltonen, Mari J.; Kluger, Carleen M.; Wild, Thomas; Kakoulidou, Aglaia; Gundelach, Jannis; Fieblinger, Tim; Fentz, Joachim; Rosinski, Jim; Obenauer, John; Greene, Jonathan R.; Liu, Longbin; Munoz-Sanjuan, Ignacio; Verhoye, Marleen; Verhaeghe, Jeroen; Bard, Jonathan; Staelens, Steven; Bertoglio, Daniele
Tracking brain maturation in vivo: functional connectivity, white matter integrity, and synaptic density in developing mice

在体追踪脑成熟：发育期小鼠的功能连接、白质完整性和突触密度

EBIOMEDICINE
IF10.8
2025-05-011
PRE
Millevert, Charissa; Vidas-Guscic, Nicholas; Adhikari, Mohit H.; Miranda, Alan; Vanherp, Liesbeth; Jonckers, Elisabeth; Joye, Philippe; Van Audekerke, Johan; Van Spilbeeck, Ignace; Verhoye, Marleen; Staelens, Steven; Bertoglio, Daniele; Weckhuysen, Sarah
The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting

脑脊液Aβ1-42/Aβ1-40比率可改善与淀粉样蛋白-PET的一致性，以在临床环境中诊断阿尔茨海默氏病

JOURNAL OF ALZHEIMERS DISEASE
IF3.1
2025-02-0674
OAAI
Niemantsverdriet, Ellis; Ottoy, Julie; Somers, Charisse; De Roeck, Ellen; Struyfs, Hanne; Soetewey, Femke; Verhaeghe, Jeroen; Van den Bossche, Tobi; Van Mossevelde, Sara; Goeman, Johan; De Deyn, Peter Paul; Marien, Peter; Versijpt, Jan; Sleegers, Kristel; Van Broeckhoven, Christine; Wyffels, Leonie; Albert, Adrien; Ceyssens, Sarah; Stroobants, Sigrid; Staelens, Steven; Bjerke, Maria; Engelborghs, Sebastiaan
Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-12-2211
PRE
Liu, Longbin; Johnson, Peter D.; Prime, Michael E.; Khetarpal, Vinod; Brown, Christopher J.; Anzillotti, Luca; Bertoglio, Daniele; Chen, Xuemei; Coe, Samuel; Davis, Randall; Dickie, Anthony P.; Esposito, Simone; Gadouleau, Elise; Giles, Paul R.; Greenaway, Catherine; Haber, James; Halldin, Christer; Haller, Scott; Hayes, Sarah; Herbst, Todd; Herrmann, Frank; Hessmann, Manuela; Hsai, Ming Min; Khani, Yaser; Kotey, Adrian; Lembo, Angelo; Mangette, John E.; Marriner, Gwendolyn A.; Marston, Richard W.; Mills, Matthew R.; Monteagudo, Edith; Forsberg-Moren, Anton; Nag, Sangram; Orsatti, Laura; Sandiego, Christine; Schaertl, Sabine; Sproston, Joanne; Staelens, Steven; Tookey, Jack; Turner, Penelope A.; Vecchi, Andrea; Veneziano, Maria; Munoz-Sanjuan, Ignacio; Bard, Jonathan; Dominguez, Celia

研究方向

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Sigrid Stroobants
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Jeroen Verhaeghe
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Leonie Wyffels
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Daniele Bertoglio
H 指数:20论文数:82被引数:881
A
Alan Miranda
H 指数:14论文数:64被引数:582
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Steven Deleye
H 指数:15论文数:61被引数:668
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Stefaan Vandenberghe
H 指数:40论文数:424被引数:6,813
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Christel Vangestel
H 指数:20论文数:66被引数:1,294
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Jonathan Bard
H 指数:34论文数:98被引数:5,634
I
Ignace Lemahieu
H 指数:38论文数:578被引数:6,375