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C

Chris Pepper

department of clinical and experimental medicine
H指数:50
被引数:6,966
浏览量:0

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TLR9-dependent migration identifies different Chronic Lymphocytic Leukemia signaling states under BTK inhibition.

TLR9依赖性迁移识别BTK抑制下慢性淋巴细胞白血病的不同信号状态。

Blood
IF23.1
2026-10-070
PRE
Emma Kennedy; Lauren Stott; Iona Ashworth; Eleni Ladikou; John Jones; Rosalynd Johnston; Aimilia Vareli; Valter Gattei; Antonella Zucchetto; Triantafillos Liloglou; Piers Patten; Sandrine Jayne; Martin J.S. Dyer; Sean Girvan; David A. Cairns; Fabio Simoes; Simon Mitchell; Chris Pepper; Andrea G.S. Pepper
Exploring the Bone Marrow Microenvironment as a Therapeutic Barrier and Targetable Source of Crosstalk in Acute Myeloid Leukemia

探索骨髓微环境作为急性髓系白血病中的治疗屏障和可靶向的串扰来源

Blood and Lymphatic Cancer-Targets and Therapy
IF4.9
2026-05-190
OAAI
Aleksandra Kolosova; Imogen Anna Mould; Chris Pepper; Simon Mitchell; Andrea GS Pepper; Eleni E Ladikou; Fabio A Simoes
Design, Synthesis, and Biological Evaluation of Efflux-Resistant Imatinib Derivatives
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-10-010
PRE
Chowdhury, Madiha M.; Pretheshan, Priantha; Chowdhury, Nasima S.; Andriollo, Paolo; Shah, Ajit J.; Forbes, Ben; Pepper, Chris; Rahman, Khondaker Miraz
Systems biology-enabled targeting of NF-κΒ and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL

系统生物学赋能的NF-κΒ和BCL2靶向克服了DLBCL中微环境介导的BH3-模拟剂耐药性

Cell Death & Disease
IF9.6
2025-08-160
OAAI
Aimilia Vareli; Haripriya Vaidehi Narayanan; Heather Clark; Eleanor Jayawant; Hui Zhou; Yi Liu; Emma Kennedy; Lauren Stott; Fabio Simoes; Alexander Hoffmann; Andrea Pepper; Chris Pepper; Simon Mitchell
Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data
BLOOD CANCER JOURNAL
IF11.6
2024-07-040
OAAI
Norris, Richard; Jones, John; Mancini, Erika; Chevassut, Timothy; Simoes, Fabio A.; Pepper, Chris; Pepper, Andrea; Mitchell, Simon
A therapeutic antibody targeting annexin-A1 inhibits cancer cell growth in vitro and in vivo
ONCOGENE
IF7.3
2024-01-105
OAAI
Al-Ali, Hussein N.; Crichton, Scott J.; Fabian, Charlene; Pepper, Chris; Butcher, David R.; Dempsey, Fiona C.; Parris, Christopher N.
Computational modeling of DLBCL predicts response to BH3-mimetics
NPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
2023-06-064
OAAI
Cloete, Ielyaas; Smith, Victoria M.; Jackson, Ross A.; Pepper, Andrea; Pepper, Chris; Vogler, Meike; Dyer, Martin J. S.; Mitchell, Simon
NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
FRONTIERS IN ONCOLOGY
IF3.3
2023-06-021
OAAI
Jayawant, Eleanor; Pack, Arran; Clark, Heather; Kennedy, Emma; Ghodke, Ankur; Jones, John; Pepper, Chris; Pepper, Andrea; Mitchell, Simon
NF-kB and the CLL microenvironment
FRONTIERS IN ONCOLOGY
IF3.3
2023-03-3017
OAAI
O'Donnell, Alice; Pepper, Chris; Mitchell, Simon; Pepper, Andrea
Synthesis and Characterization of NUC-7738, an Aryloxy Phosphoramidate of 3′-Deoxyadenosine, as a Potential Anticancer Agent
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-11-2310
OAAI
Serpi, Michaela; Ferrari, Valentina; McGuigan, Christopher; Ghazaly, Essam; Pepper, Chris
DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies
COMMUNICATIONS BIOLOGY
IF5.1
2022-07-292
OAAI
Procopiou, George; Jackson, Paul J. M.; di Mascio, Daniella; Auer, Jennifer L.; Pepper, Chris; Rahman, Khondaker Miraz; Fox, Keith R.; Thurston, David E.
MDX-124, a novel annexin-A1 antibody, shows anti-tumor efficacy in several preclinical models of triple-negative breast cancer
CANCER RESEARCH
IF16.6
2022-02-150
PRE
Dempsey, Fiona C.; Al-Ali, Hussein; Crichton, Scott J.; Fabian, Charlene; Pepper, Chris; Parris, Christopher N.
TP53 Mutations with Low Variant Allele Frequency Predict Short Survival in Chronic Lymphocytic Leukemia
CLINICAL CANCER RESEARCH
IF10.2
2021-07-2032
OA
Bomben, Riccardo; Rossi, Francesca Maria; Vit, Filippo; Bittolo, Tamara; D'Agaro, Tiziana; Zucchetto, Antonella; Tissino, Erika; Pozzo, Federico; Vendramini, Elena; Degan, Massimo; Zaina, Eva; Cattarossi, Ilaria; Varaschin, Paola; Nanni, Paola; Berton, Michele; Braida, Alessandra; Polesel, Jerry; Cohen, Jared A.; Santinelli, Enrico; Biagi, Annalisa; Gentile, Massimo; Morabito, Fortunato; Fronza, Gilberto; Pozzato, Gabriele; D'Arena, Giovanni; Olivieri, Jacopo; Bulian, Pietro; Pepper, Chris; Hockaday, Anna; Schuh, Anna; Hillmen, Peter; Rossi, Davide; Chiarenza, Annalisa; Zaja, Francesco; Di Raimondo, Francesco; Del Poeta, Giovanni; Gattei, Valter
Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies
LEUKEMIA
IF13.4
2021-06-194
OAAI
Pepper, Andrea G. S.; Zucchetto, Antonella; Norris, Kevin; Tissino, Erika; Polesel, Jerry; Soe, Zarni; Allsup, David; Hockaday, Anna; Ow, Pei Loo; Hillmen, Peter; Rawstron, Andrew; Catovsky, Daniel; Bulian, Pietro; Bomben, Riccardo; Baird, Duncan M.; Fegan, Christopher D.; Gattei, Valter; Pepper, Chris
Single Diastereomers of the Clinical Anticancer ProTide Agents NUC-1031 and NUC-3373 Preferentially Target Cancer Stem Cells In Vitro
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-06-0413
OAAI
Slusarczyk, Magdalena; Serpi, Michaela; Ghazaly, Essam; Kariuki, Benson M.; McGuigan, Christopher; Pepper, Chris
Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-03-0116
OAAI
Shao, Hao; Foley, David W.; Huang, Shiliang; Abbas, Abdullahi Y.; Lam, Frankie; Gershkovich, Pavel; Bradshaw, Tracey D.; Pepper, Chris; Fischer, Peter M.; Wang, Shudong
Transcriptomics-Based Characterization of the Toxicity of ZnO Nanoparticles Against Chronic Myeloid Leukemia Cells
INTERNATIONAL JOURNAL OF NANOMEDICINE
IF6.5
2020-10-0123
OAAI
Alsagaby, Suliman A.; Vijayakumar, Rajendran; Premanathan, Mariappan; Mickymaray, Suresh; Alturaiki, Wael; Al-Baradie, Raid S.; AlGhamdi, Saleh; Aziz, Mohammad A.; Alhumaydhi, Fahad A.; Alzahrani, Faisal A.; Alwashmi, Ameen S.; Al Abdulmonem, Waleed; Alharbi, Naif Khalaf; Pepper, Chris
Novel pyrrolobenzodiazepine benzofused hybrid molecules inhibit nuclear factor-KB activity and synergize with bortezomib and ibrutinib in hematologic cancers
HAEMATOLOGICA
IF7.9
2020-05-076
OAAI
Lewis, Thomas; Corcoran, David B.; Thurston, David E.; Giles, Peter J.; Ashelford, Kevin; Walsby, Elisabeth J.; Fegan, Christopher D.; Pepper, Andrea G. S.; Rahman, Khondaker Miraz; Pepper, Chris
Clinical utility of telomere length measurements in cancer
CURRENT OPINION IN GENETICS & DEVELOPMENT
IF3.6
2020-02-014
OAAI
Pepper, Chris; Norris, Kevin; Fegan, Christopher
Targeting CDK9 for treatment of colorectal cancer
MOLECULAR ONCOLOGY
IF4.5
2019-08-2140
OAAI
Rahaman, Muhammed H.; Lam, Frankie; Zhong, Longjin; Teo, Theodosia; Adams, Julian; Yu, Mingfeng; Milne, Robert W.; Pepper, Chris; Lokman, Noor A.; Ricciardelli, Carmela; Oehler, Martin K.; Wang, Shudong

研究方向

暂未获取到该数据
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Chris Fegan
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Guy Pratt
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D
David Allsup
H 指数:35论文数:169被引数:5,426
D
Daniel Catovsky
H 指数:100论文数:705被引数:4.9万
R
Richard S. Houlston
H 指数:120论文数:1,250被引数:6.1万
J
James M. Allan
H 指数:56论文数:235被引数:1.1万
D
David E. Thurston
H 指数:45论文数:341被引数:7,111
M
Martin J.S. Dyer
H 指数:91论文数:517被引数:2.8万
A
Andrea Pepper
H 指数:11论文数:39被引数:553
K
Khondaker Miraz Rahman
H 指数:33论文数:272被引数:4,525