Wim Annaert - Publications, H-index & Citations

Wim Annaert

vib

59H指数

197论文数

1.7W被引数

收录论文 87

发表时间

Atypical chemokine receptor 3 regulates synaptic removal in disease astrocytes 非典型趋化因子受体3调控病变星形胶质细胞中的突触清除

Molecular Neurodegeneration

IF17.5

2026-07-15

OAAI

V. Giusti; J. Park; E. Giusto; L. Masatti; P. Ramos-Gonzalez; L. Iovino; M. Sandre; A. Emmi; G. Kaur; E. Coletto; Zoë P. Van Acker; W. Annaert; E. Calura; F. Petrelli; A. Porzionato; R. De Caro; F. Cavaliere; W. S. Chung; L. Civiero

Amyloid precursor protein carboxy-terminal fragments as catalyzers of endolysosomal dysfunction in Alzheimer’s disease 阿尔茨海默病中，淀粉样前体蛋白羧基末端片段作为内溶酶体功能障碍的催化剂。

Trends in Neurosciences

IF15.1

2025-06-12

OAAI

Céline Vrancx; Wim Annaert

Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes γ-分泌酶功能障碍谱作为PSEN1、PSEN2和APP致病基因中常染色体显性遗传阿尔茨海默病(ADAD)发病年龄的统一预测因子

MOLECULAR NEURODEGENERATION

IF17.5

2025-04-26

OAAI

Fernandez, Sara Gutierrez; Oria, Cristina Gan; Petit, Dieter; Annaert, Wim; Ringman, John M.; Fox, Nick C.; Ryan, Natalie S.; Chavez-Gutierrez, Lucia

Proximal partners of the organellar N-terminal acetyltransferase NAA60: insights into Golgi structure and transmembrane protein topology 细胞器N-末端乙酰转移酶NAA60的近端伴侣：对高尔基体结构和跨膜蛋白拓扑结构的见解

Open Biology

IF3.6

2025-02-19

OAAI

Sebastian Tanco; Veronique Jonckheere; Arun Kumar Tharkeshwar; Annelies Bogaert; Kris Gevaert; Wim Annaert; Petra Van Damme

Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer's disease-relevant brain circuits Presenilin2的表达改变会影响阿尔茨海默氏病相关脑回路中的溶酶体内稳态和突触功能

NATURE COMMUNICATIONS

IF15.7

2024-11-29

OAAI

Perdok, Anika; Van Acker, Zoe P.; Vrancx, Celine; Sannerud, Ragna; Vorsters, Inge; Verrengia, Assunta; Callaerts-Vegh, Zsuzsanna; Creemers, Eline; Fernandez, Sara Gutierrez; D'hauw, Britt; Serneels, Lutgarde; Wierda, Keimpe; Chavez-Gutierrez, Lucia; Annaert, Wim

Mitochondrial dysfunction, cause or consequence in neurodegenerative diseases?

BIOESSAYS

IF2.7

2024-10-04

OAAI

Van Acker, Zoe P.; Leroy, Thomas; Annaert, Wim

Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites

DEVELOPMENTAL CELL

IF8.7

2024-06-01

OAAI

Bretou, Marine; Sannerud, Ragna; Escamilla-Ayala, Abril; Leroy, Tom; Vrancx, Celine; Van Acker, Zoe P.; Perdok, Anika; Vermeire, Wendy; Vorsters, Inge; Van Keymolen, Sophie; Maxson, Michelle; Pavie, Benjamin; Wierda, Keimpe; Eskelinen, Eeva-Liisa; Annaert, Wim

Maintenance of proteostasis by Drosophila Rer1 is essential for competitive cell survival and Myc-driven overgrowth

PLOS GENETICS

IF3.7

2024-02-26

OAAI

Paul, Pranab Kumar; Umarvaish, Shruti; Bajaj, Shivani; Farin, S. Rishana; Mohan, Hrudya; Annaert, Wim; Chaudhary, Varun

Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism

NATURE COMMUNICATIONS

IF15.7

2023-05-24

OAAI

Van Acker, Zoe P.; Perdok, Anika; Hellemans, Ruben; North, Katherine; Vorsters, Inge; Cappel, Cedric; Dehairs, Jonas; Swinnen, Johannes V.; Sannerud, Ragna; Bretou, Marine; Damme, Markus; Annaert, Wim

Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-06-21

OAAI

Vrijsen, Stephanie; Vrancx, Celine; Del Vecchio, Mara; Swinnen, Johannes V.; Agostinis, Patrizia; Winderickx, Joris; Vangheluwe, Peter; Annaert, Wim

The microglial lysosomal system in Alzheimer's disease: Guardian against proteinopathy 阿尔茨海默氏病中的小胶质溶酶体系统: 蛋白质病的监护人

AGEING RESEARCH REVIEWS

IF12.4

2021-11-01

OAAI

Van Acker, Zoe P.; Perdok, Anika; Bretou, Marine; Annaert, Wim

Assembly of γ-secretase occurs through stable dimers after exit from the endoplasmic reticulum

JOURNAL OF CELL BIOLOGY

IF6.4

2021-07-22

OAAI

Wouters, Rosanne; Michiels, Christine; Sannerud, Ragna; Kleizen, Bertrand; Dillen, Katleen; Vermeire, Wendy; Ayala, Abril Escamilla; Demedts, David; Schekman, Randy; Annaert, Wim

BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis BNIP3通过抑制细胞内铁稳态促进hif-1α 驱动的黑色素瘤生长

EMBO JOURNAL

IF8.3

2021-05-01

OAAI

Vara-Perez, Monica; Rossi, Matteo; van den Haute, Chris; Maes, Hannelore; Sassano, Maria Livia; Venkataramani, Vivek; Michalke, Bernhard; Romano, Erminia; Rillaerts, Kristine; Garg, Abhishek D.; Schepkens, Corentin; Bosisio, Francesca M.; Wouters, Jasper; Oliveira, Ana Isabel; Vangheluwe, Peter; Annaert, Wim; Swinnen, Johannes, V; Colet, Jean Marie; van den Oord, Joost J.; Fendt, Sarah-Maria; Mazzone, Massimiliano; Agostinis, Patrizia

The Nanoscopic Organization of Synapse Structures: A Common Basis for Cell Communication

MEMBRANES

IF3.6

2021-03-30

OAAI

Yang, Xiaojuan; Annaert, Wim

Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson's disease

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2021-02-12

OAAI

Smolders, Stefanie; Philtjens, Stephanie; Crosiers, David; Sieben, Anne; Hens, Elisabeth; Heeman, Bavo; Van Mossevelde, Sara; Pals, Philippe; Asselbergh, Bob; Dos Santos Dias, Roberto; Vermeiren, Yannick; Vandenberghe, Rik; Engelborghs, Sebastiaan; De Deyn, Peter Paul; Martin, Jean-Jacques; Cras, Patrick; Annaert, Wim; Van Broeckhoven, Christine

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Hamouda, Norin Nabil; Van den Haute, Chris; Vanhoutte, Roeland; Sannerud, Ragna; Azfar, Mujahid; Mayer, Rupert; Calabuig, Alvaro Cortes; Swinnen, Johannes, V; Agostinis, Patrizia; Baekelandt, Veerle; Annaert, Wim; Impens, Francis; Verhelst, Steven H. L.; Eggermont, Jan; Martin, Shaun; Vangheluwe, Peter

PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Soares, Alberto Carpinteiro; Ferreira, Andreia; Marieen, Jonas; Delay, Charlotte; Lee, Edward; Trojanowski, John Q.; Moechars, Dieder; Annaert, Wim; De Muynck, Louis

Bring it back, bring it back, don't take it away from me - the sorting receptor RER1

JOURNAL OF CELL SCIENCE

IF3.6

2020-09-01

OAAI

Annaert, Wim; Kaether, Christoph

Contribution of the Presenilins in the cell biology, structure and function of γ-secretase

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2020-09-01

OAAI

Escamilla-Ayala, Abril; Wouters, Rosanne; Sannerud, Ragna; Annaert, Wim

Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface

ELIFE

IF0

2020-07-07

OAAI

Escamilla-Ayala, Abril Angelica; Sannerud, Ragna; Mondin, Magali; Poersch, Karin; Vermeire, Wendy; Paparelli, Laura; Berlage, Caroline; Koenig, Marcelle; Chavez-Gutierrez, Lucia; Ulbrich, Maximilian H.; Munck, Sebastian; Mizuno, Hideaki; Annaert, Wim

研究方向