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J

James M. Murphy

monash university

89H指数
486论文数
2.6W被引数
收录论文 187
发表时间
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Black Sheep: Pseudokinases Bucking the Trend to Reveal Non-Catalytic Kinase Functions黑羊：伪激酶逆势而为揭示非催化性激酶功能
errIUBMB Life
IF3.2
err2026-09-12
err0
errOAAI
errJames M. Murphy; Natalia Jura; Peter D. Mace
err分享
err收藏
An Ancestral Mechanism of Calmodulin Binding to Cds1 Kinase Inhibits Catalytic Activity钙调蛋白与Cds1激酶结合的祖先机制抑制催化活性
errIUBMB Life
IF3.2
err2026-09-12
err0
errOAAI
errStephanie A. Manovella; Tingting Wang; Samuel N. Young; Toby A. Dite; Vineet Vaibhav; Steve Binos; Laura F. Dagley; Anh T. N. Nguyen; Anthony R. Means; Janni Petersen; John W. Scott; James M. Murphy; Christopher R. Horne
err分享
err收藏
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease坏死性凋亡到凋亡的信号轴是炎症性肠病的病理基础
errScience
IF45.8
err2026-08-27
err0
PREAI
errJiyi Pang; Aysha H. Al-Ani; Komal M. Patel; Yunzhuo Zhou; Samuel N. Young; Jinjin Chen; Isabella Kong; Marilou Barrios; James A. Rickard; Siqi Chen; Xiuquan Ma; Farzaneh Shojaee; Seong-Beom Kim; Siavash Foroughi; Wayne Cawthorne; Annette V. Jacobsen; Asha Jois; Ashley L. Weir; Lachlan W. Whitehead; Pradeep Rajasekhar; Christopher R. Horne; Ruqian Lyu; Lucy J. Mather; Raymond K. H. Yip; Ellen Tsui; Imadh Azeez; Tao Tan; Weiwei Liang; Suresh Sivanesan; Andrew Metz; Ash Patwardhan; Natalie Shea; Guru Iyngkaran; Daniel Schneider; Alexander T. Elford; William Beattie; Finlay Macrae; Gianmaria Liccardi; Henning Walczak; Yuxia Zhang; Oliver M. Sieber; Tim Spelman; Lisa Giulino-Roth; Michael Christie; Yunshun Chen; Kelly L. Rogers; Rory Bowden; Sandra E. Nicholson; Kate E. Lawlor; Edwin D. Hawkins; Britt Christensen; Andre L. Samson; James E. Vince; James M. Murphy
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Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects低激动活性和平衡通路调节区分了一种缺乏胆碱能不良反应的M1毒蕈碱受体正向别构调节剂
errACS Chemical Neuroscience
IF3.9
err2026-06-30
err0
PREAI
errHuong T. M. Nguyen; Elham Khajehali; Vi Pham; John W. Scott; Toby A. Dite; Laura F. Dagley; James M. Murphy; Geoff Thompson; Andrew B. Tobin; David M. Thal; Arthur Christopoulos; Emma T. van der Westhuizen; Celine Valant
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Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitisBECLIN1单倍剂量不足对杯状细胞功能和结肠炎易感性的影响
errCell Death & Disease
IF9.6
err2026-06-17
err0
errOAAI
errJuliani Juliani; Sharon Tran; Tiffany J. Harris; Sarah L. Ellis; Aysha H. Al-Ani; Yashodha Wijebandara; Komal M. Patel; Samuel N. Young; Marco Evangelista; David Baloyan; Camilla M. Reehorst; Rebecca Nightingale; Laura J. Jenkins; Peter De Cruz; Kinga Duszyc; Benjamin T. Kile; Alpha S. Yap; John M. Mariadason; Britt Christensen; André L. Samson; James M. Murphy; Walter D. Fairlie; Erinna F. Lee
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Inspiring discovery through reviews and visualization in biochemistry通过综述和可视化在生物化学领域激发发现
errTrends in Biochemical Sciences
IF11
err2026-04-02
err0
PREAI
errJames M. Murphy; Arthur J. Olson
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err收藏
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexesIAP基生物降解剂可将坏死性凋亡转化为凋亡并消除癌症驱动蛋白复合物
errCell Chemical Biology
IF7.2
err2026-03-31
err0
errOAAI
errXiuquan Ma; François Vaillant; Deepagan Gopal; Kael Schoffer; Farzaneh Shojaee; Jiyi Pang; Christopher A. Baldwin; James M. Murphy; John Silke; Maria C. Tanzer; Jane E. Visvader; Ranja Salvamoser; James E. Vince
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Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy肿瘤和基质区室中的坏死性凋亡决定了对免疫原性细胞死亡为基础的免疫治疗的反应性
errNature Communications
IF15.7
err2026-03-01
err0
errOAAI
errFernando, Winnie; Clucas, Jarama; Rizzo, Alberto; Singer, Ramsay; Goode, Emily; Tiu, Crescens; Layzell, Scott; Konecnik, Joshua; Wilson, Rebecca; John, Sidonie Wicky; Jouny, Samuel; Guppy, Naomi; Boulat, Victoire; Mannion, Jonathan; Goicoechea, Maria; Tan, Shaun; Lawson, Sam; Starling, Chris; Elshtein, Gabrielle; Ravindran, Nivedita; Montgomery, Anna B.; Andres-Ejarque, Rosa; Allen, Mark; Lumbard, Steven; Wallberg, Fredrik; Betteridge, Kai; Scrimgeour, Ross; Robertson, David; Ward, George; Sims, Martin; Smyth, Tomoko; Samson, Andre L.; Murphy, James M.; Ivankovic, Daniela Kolarevic; Arwert, Esther N.; Calado, Dinis P.; Grigoriadis, Anita; Smalley, Matthew J.; Melcher, Alan; Haider, Syed; Lawrence, Toby; Roxanis, Ioannis; Tutt, Andrew N. J.; Tenev, Tencho; Meier, Pascal
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The kinase domain of RIPK3 tunes its scaffolding functionsRIPK3激酶结构域调控其支架功能
errCell Death and Differentiation
IF15.4
err2026-02-01
err1
PREAI
errChiou, Shene; Horne, Christopher R.; Patel, Komal M.; Preaudet, Adele; Rickard, James A.; Young, Samuel N.; Jois, Asha; Garnish, Sarah E.; Hempel, Anne; Hall, Cathrine; Hildebrand, Joanne M.; Kueh, Andrew J.; Silke, John; Putoczki, Tracy L.; Hawkins, Edwin D.; Samson, Andre L.; Murphy, James M.
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Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity钙调素对CHK2激酶的非典型结合抑制其催化活性
errBIOCHEMICAL JOURNAL
IF4.3
err2025-12-01
err0
errOAAI
errHorne, Christopher R.; Wang, Tingting; Young, Samuel N.; Dite, Toby A.; Nyvall, Hunter G.; Suresh, Sushant; Davies, Katherine A.; Castro, Abner Gonzalez; Vaibhav, Vineet; Mather, Lucy J.; Dagley, Laura F.; Belousoff, Matthew J.; Manning, Gerard; Means, Anthony R.; Burke, John E.; Petersen, Janni; Scott, John W.; Murphy, James M.
err分享
err收藏
Inhibition of RIPK1 or RIPK3 kinase activity post ischemia-reper fusion reduces the development of chronic kidney injury
errBIOCHEMICAL JOURNAL
IF4.3
err2025-01-21
err0
errOAAI
errPefanis, Aspasia; Bongoni, Anjan K.; Mcrae, Jennifer L.; Salvaris, Evelyn J.; Fisicaro, Nella; Murphy, James M.; Ierino, Francesco L.; Cowan, Peter J.
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MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions
errCELL DEATH & DISEASE
IF9.6
err2024-11-21
err0
errOAAI
errChiou, Shene; Cawthorne, Wayne; Soerianto, Thomas; Hofferek, Vinzenz; Patel, Komal M.; Garnish, Sarah E.; Crutchfield, Emma C. Tovey; Hall, Cathrine; Hildebrand, Joanne M.; McConville, Malcolm J.; Lawlor, Kate E.; Hawkins, Edwin D.; Samson, Andre L.; Murphy, James M.
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err收藏
Divergent roles of RIPK3 and MLKL in high-fat diet-induced obesity and MAFLD in mice
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-11-12
err0
errOAAI
errTye, Hazel; Conos, Stephanie A.; Djajawi, Tirta M.; Gottschalk, Timothy A.; Abdoulkader, Nasteho; Kong, Isabella Y.; Kammoun, Helene L.; Narayana, Vinod K.; Kratina, Tobias; Speir, Mary; Emery, Jack; Simpson, Daniel S.; Hall, Cathrine; Vince, Angelina J.; Russo, Sophia; Crawley, Rhiannan; Rashidi, Maryam; Hildebrand, Joanne M.; Murphy, James M.; Whitehead, Lachlan; De Souza, David P.; Masters, Seth L.; Samson, Andre L.; Lalaoui, Najoua; Hawkins, Edwin D.; Murphy, Andrew J.; Vince, James E.; Lawlor, Kate E.
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Death at a funeral: Activation of the dead enzyme, MLKL, to kill cells by necroptosis
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2024-10-01
err1
errOAAI
errDavies, Katherine A.; Czabotar, Peter E.; Murphy, James M.
err分享
err收藏
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation
errBIOCHEMICAL JOURNAL
IF4.3
err2024-08-27
err1
errOAAI
errGarnish, Sarah E.; Horne, Christopher R.; Meng, Yanxiang; Young, Samuel N.; Jacobsen, Annette, V; Hildebrand, Joanne M.; Murphy, James M.
err分享
err收藏
Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1
errPLANT PHYSIOLOGY
IF6.9
err2024-05-15
err2
errOAAI
errDiplock, Nathan; Baudin, Mael; Xiang, Xincheng (Derek); Liang, Lung-Yu; Dai, Weiwen; Murphy, James M.; Lucet, Isabelle S.; Hassan, Jana A.; Lewis, Jennifer D.
err分享
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An immunohistochemical atlas of necroptotic pathway expression
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-05-15
err6
errOAAI
errChiou, Shene; Al-Ani, Aysha H.; Pan, Yi; Patel, Komal M.; Kong, Isabella Y.; Whitehead, Lachlan W.; Light, Amanda; Young, Samuel N.; Barrios, Marilou; Sargeant, Callum; Rajasekhar, Pradeep; Zhu, Leah; Hempel, Anne; Lin, Ann; Rickard, James A.; Hall, Cathrine; Gangatirkar, Pradnya; Yip, Raymond K. H.; Cawthorne, Wayne; Jacobsen, Annette, V; Horne, Christopher R.; Martin, Katherine R.; Ioannidis, Lisa J.; Hansen, Diana S.; Day, Jessica; Wicks, Ian P.; Law, Charity; Ritchie, Matthew E.; Bowden, Rory; Hildebrand, Joanne M.; O'Reilly, Lorraine A.; Silke, John; Giulino-Roth, Lisa; Tsui, Ellen; Rogers, Kelly L.; Hawkins, Edwin D.; Christensen, Britt; Murphy, James M.; Samson, Andre L.
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Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-04-16
err1
errOAAI
errLiang, Lung-Yu; Geoghegan, Niall D.; Mlodzianoski, Michael; Leis, Andrew; Whitehead, Lachlan W.; Surudoi, Minglyanna G.; Young, Samuel N.; Janes, Peter; Shepherd, Doulin; Ghosal, Debnath; Rogers, Kelly L.; Murphy, James M.; Lucet, Isabelle S.
err分享
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Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases
errIMMUNITY
IF26.3
err2024-03-01
err8
PREAI
errLawlor, Kate E.; Murphy, James M.; Vince, James E.
err分享
err收藏
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo
errCELL DEATH & DISEASE
IF9.6
err2024-01-30
err7
errOAAI
errBader, Stefanie M.; Cooney, James P.; Bhandari, Reet; Mackiewicz, Liana; Dayton, Merle; Sheerin, Dylan; Georgy, Smitha Rose; Murphy, James M.; Davidson, Kathryn C.; Allison, Cody C.; Pellegrini, Marc; Doerflinger, Marcel
err分享
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研究方向

暂无研究方向
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