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H

Harpreet K. Saini

astex pharmaceuticals
H指数:25
被引数:7,672

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The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1

GBA1的注释已被其蛋白质编码假基因GBAP1所掩盖

SCIENCE ADVANCES
IF12.5
2024-06-283
OAAI
Gustavsson, Emil K.; Sethi, Siddharth; Gao, Yujing; Brenton, Jonathan W.; Garcia-Ruiz, Sonia; Zhang, David; Garza, Raquel; Reynolds, Regina H.; Evans, James R.; Chen, Zhongbo; Grant-Peters, Melissa; Macpherson, Hannah; Montgomery, Kylie; Dore, Rhys; Wernick, Anna I.; Arber, Charles; Wray, Selina; Gandhi, Sonia; Esselborn, Julian; Blauwendraat, Cornelis; Douse, Christopher H.; Adami, Anita; Atacho, Diahann A. M.; Kouli, Antonina; Quaegebeur, Annelies; Barker, Roger A.; Englund, Elisabet; Platt, Frances; Jakobsson, Johan; Wood, Nicholas W.; Houlden, Henry; Saini, Harpreet; Bento, Carla F.; Hardy, John; Ryten, Mina
Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile
CANCER RESEARCH
IF16.6
2024-03-221
PRE
Ahn, Maria; Bevan, Luke; Buck, Ildiko; Cano, Celine; Castro, Juan; Cons, Ben; Endicott, Jane; Fazal, Lynsey; Ferrari, Nicola; Hardcastle, Ian; Hearn, Keisha; Holvey, Rhian; Howard, Steven; Johnson, Chris; Jennings, Claire; Kucia-Tran, Justyna; Kyle, Suzanne; Lunec, John; Lyons, John; Miller, Duncan; Rees, David; Noble, Martin; Newell, David R.; Reeks, Judith; Saini, Harpreet; Denis, Jeffrey St.; Tamanini, Emiliano; Thomas, Huw; Thompson, Neil; Vinkovic, Mladen; Ward, George; Wallis, Nicola; Walton, Hugh; Wedge, Stephen; Williams, Pamela; Willmore, Elaine; Wilshire, Nicola; Zhao, Yan; Chessari, Gianni
Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-05-1845
PREAI
Heightman, Tom D.; Berdini, Valerio; Braithwaite, Hannah; Buck, Ildiko M.; Cassidy, Megan; Castro, Juan; Courtin, Aurelie; Day, James E. H.; East, Charlotte; Fazal, Lynsey; Graham, Brent; Griffiths-Jones, Charlotte M.; Lyons, John F.; Martins, Vanessa; Muench, Sandra; Munck, Joanne M.; Norton, David; O'Reilly, Marc; Palmer, Nick; Pathuri, Puja; Reader, Michael; Rees, David C.; Rich, Sharna J.; Richardson, Caroline; Saini, Harpreet; Thompson, Neil T.; Wallis, Nicola G.; Walton, Hugh; Wilsher, Nicola E.; Woolford, Alison J. -A.; Cooke, Michael; Cousin, David; Onions, Stuart; Shannon, Jonathan; Watts, John; Murray, Christopher W.
Fragment-based discovery of a highly potent, orally bioavailable ERK1/2 inhibitor that modulates the phosphorylation and catalytic activity of ERK1/2
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-010
PRE
Heightman, Tom D.; Berdini, Valerio; Braithwaite, Hannah; Buck, Ildiko; Cassidy, Megan; Castro, Juan; Courtin, Aurelie; Day, James; East, Charlotte; Fazal, Lynsey; Graham, Brent; Griffiths-Jones, Charlotte; Lyons, John; Martins, Vanessa; Muench, Sandra; Munck, Joanne; Norton, David; O'Reilly, Marc; Palmer, Nick; Pathuri, Puja; Reader, Mike; Rees, David; Rich, Sharna; Richardson, Caroline; Saini, Harpreet; Thompson, Neil; Wallis, Nicola; Walton, Hugh; Wilsher, Nicola; Woolford, Alison; Murray, Chris
Characterization of a novel ERK1/2 inhibitor, which modulates the phosphorylation and catalytic activity of ERK1/2
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-010
PRE
Munck, Joanne M.; Berdini, Valerio; Bevan, Luke D.; Braithwaite, Hannah; Buck, Ildiko M.; Cassidy, Megan; Castro, Juan; Courtin, Aurelie; Day, James E.; East, Charlotte; Fazal, Lynsey; Graham, Brent; Griffiths-Jones, Charlotte M.; Heightman, Tom D.; Hindley, Chris J.; Kidane, Birikiti; Kucia-Tran, Justyna; Lyons, John F.; Martins, Vanessa; Muench, Sandra; Murray, Chris W.; Norton, David; O'Reilly, Marc; Palmer, Nick; Pathuri, Puja; Reader, Mike; Rees, David C.; Rich, Sharna J.; Richardson, Caroline J.; Saini, Harpreet K.; Shah, Alpesh; Stanczuk, Lukas; Thompson, Neil T.; Walton, Hugh; Wilsher, Nicola E.; Woolford, Alison J.; Wallis, Nicola G.
Extracellular vesicles are independent metabolic units with asparaginase activity

细胞外囊泡是具有天冬酰胺酶活性的独立代谢单位

NATURE CHEMICAL BIOLOGY
IF13.7
2017-07-03113
OAAI
Iraci, Nunzio; Gaude, Edoardo; Leonardi, Tommaso; Costa, Ana S. H.; Cossetti, Chiara; Peruzzotti-Jametti, Luca; Bernstock, Joshua D.; Saini, Harpreet K.; Gelati, Maurizio; Vescovi, Angelo Luigi; Bastos, Carlos; Faria, Nuno; Occhipinti, Luigi G.; Enright, Anton J.; Frezza, Christian; Pluchino, Stefano

研究方向

暂未获取到该数据
A
Anton J. Enright
H 指数:70论文数:218被引数:4.2万
N
Nicholas Coleman
H 指数:65论文数:333被引数:1.5万
M
Matthew J. Murray
H 指数:38论文数:248被引数:5,403
J
James C. Nicholson
H 指数:44论文数:261被引数:7,885
S
Stijn van Dongen
H 指数:35论文数:91被引数:1.6万
N
Nicola G. Wallis
H 指数:28论文数:130被引数:2,744
C
Cinzia G. Scarpini
H 指数:24论文数:143被引数:1,924
M
Mark R. Pett
H 指数:21论文数:123被引数:2,475
N
Neil T. Thompson
H 指数:29论文数:199被引数:2,624
J
Joanne M. Munck
H 指数:16论文数:132被引数:1,026