Anne Grapin‐Botton - Publications, H-index & Citations

Anne Grapin‐Botton

Max Planck Institute of Molecular Cell Biology and Genetics

42H指数

125论文数

6.0K被引数

收录论文 50

发表时间

High-content screening of organoids reveals the mechanisms of human pancreas acinar specification

Cell Stem Cell

IF20.4

2026-01-21

OAAI

Rashmiparvathi Keshara; Karolina Kuodyte; Antje Janosch; Cordula Andree; Marc Bickle; Martin Stöter; Rico Barsacchi; Yung Hae Kim; Anne Grapin-Botton

Permeability-driven pressure and cell proliferation control lumen morphogenesis in pancreatic organoids 通透性驱动的压力和细胞增殖控制胰腺类器官的管腔形态发生

Nature Cell Biology

IF19.1

2025-12-19

OAAI

Byung Ho Lee; Kana Fuji; Heike Petzold; Phil Seymour; Siham Yennek; Coline Schewin; Allison Lewis; Daniel Riveline; Tetsuya Hiraiwa; Masaki Sano; Anne Grapin-Botton

Integrating single-cell imaging and RNA sequencing datasets links differentiation and morphogenetic dynamics of human pancreatic endocrine progenitors

DEVELOPMENTAL CELL

IF8.7

2023-11-01

OAAI

Beydag-Tasoez, Belin Selcen; D'Costa, Joyson Verner; Hersemann, Lena; Lee, Byung Ho; Luppino, Federica; Kim, Yung Hae; Zechner, Christoph; Grapin-Botton, Anne

Emerging principles of primary cilia dynamics in controlling tissue organization and function

EMBO JOURNAL

IF8.3

2023-09-25

OAAI

Gopalakrishnan, Jay; Feistel, Kerstin; Friedrich, Benjamin M.; Grapin-Botton, Anne; Jurisch-Yaksi, Nathalie; Mass, Elvira; Mick, David U.; Mueller, Roman-Ulrich; May-Simera, Helen; Schermer, Bernhard; Schmidts, Miriam; Walentek, Peter; Wachten, Dagmar

Mapping and exploring the organoid state space using synthetic biology

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2023-05-01

PREAI

Tan, Tzer Han; Liu, Jifeng; Grapin-Botton, Anne

RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Thompson, Nancy; Gesina, Emilie; Scheinert, Peter; Bucher, Philipp; Grapin-Botton, Anne

Towards a better understanding of diabetes mellitus using organoid models

nature reviews endocrinology

IF40

2023-01-20

OAAI

Beydag-Tasoez, Belin Selcen; Yennek, Siham; Grapin-Botton, Anne

Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

NATURE COMMUNICATIONS

IF15.7

2022-10-21

OAAI

Katsumoto, Keiichi; Yennek, Siham; Chen, Chunguang; Silva, Luis Fernando Delgadillo; Traikov, Sofia; Sever, Dror; Azad, Ajuna; Shan, Jingdong; Vainio, Seppo; Ninov, Nikolay; Speier, Stephan; Grapin-Botton, Anne

Organoid Imaging: Seeing Development and Function

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY

IF11.4

2022-10-06

PREAI

Keshara, Rashmiparvathi; Kim, Yung Hae; Grapin-Botton, Anne

Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates 13 cell differentiation

STEM CELL REPORTS

IF5.1

2022-05-01

OAAI

Nakamura, Akiko; Wong, Yan Fung; Venturato, Andrea; Michaut, Magali; Venkateswaran, Seshasailam; Santra, Mithun; Goncalves, Carla; Larsen, Michael; Leuschner, Marit; Kim, Yung Hae; Brickman, Joshua; Bradley, Mark; Grapin-Botton, Anne

Stem cell-derived β cells go in monkeys

CELL STEM CELL

IF20.4

2022-04-01

OAAI

Grapin-Botton, Anne; Ludwig, Barbara

Epithelial morphogenesis in organoids

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2022-02-01

PREAI

Lee, Byung Ho; Seijo-Barandiaran, Irene; Grapin-Botton, Anne

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

NATURE COMMUNICATIONS

IF15.7

2021-05-25

OAAI

Goncalves, Carla A.; Larsen, Michael; Jung, Sascha; Stratmann, Johannes; Nakamura, Akiko; Leuschner, Marit; Hersemann, Lena; Keshara, Rashmiparvathi; Perlman, Signe; Lundvall, Lene; Thuesen, Lea Langhoff; Hare, Kristine Juul; Amit, Ido; Jorgensen, Anne; Kim, Yung Hae; del Sol, Antonio; Grapin-Botton, Anne

Regeneration of the pancreas: proliferation and cellular conversion of surviving cells

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2020-10-01

PREAI

Sever, Dror; Grapin-Botton, Anne

Nutrients men-TOR β-Cells to Adulthood

DEVELOPMENTAL CELL

IF8.7

2020-07-01

OAAI

Katsumoto, Keiichi; Grapin-Botton, Anne

Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity

CELL REPORTS

IF6.9

2020-05-01

OAAI

Flasse, Lydie; Yennek, Siham; Cortijo, Cedric; Barandiaran, Irene Seijo; Kraus, Marine R-C; Grapin-Botton, Anne

Bromodomain and Extra Terminal Protein Inhibitors Promote Pancreatic Endocrine Cell Fate

DIABETES

IF7.5

2019-01-17

OAAI

Huijbregts, Lukas; Petersen, Maja Borup Kjaer; Berthault, Claire; Hansson, Mattias; Aiello, Virginie; Rachdi, Latif; Grapin-Botton, Anne; Honore, Christian; Scharfmann, Raphael

Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

GASTROENTEROLOGY

IF25.1

2018-10-01

PREAI

Petersen, Natalia; Frimurer, Thomas M.; Pedersen, Marianne Terndrup; Egerod, Kristoffer L.; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.; Grapin-Botton, Anne; Jensen, Kim B.; Schwartz, Thue W.

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

MOLECULAR METABOLISM

IF6.6

2018-02-01

112

OAAI

Tsonkova, Violeta Georgieva; Sand, Fredrik Wolfhagen; Wolf, Xenia Asbaek; Grunnet, Lars Groth; Ringgaard, Anna Kirstine; Ingvorsen, Camilla; Winkel, Louise; Kalisz, Mark; Dalgaard, Kevin; Bruun, Christine; Fels, Johannes Josef; Helgstrand, Charlotte; Hastrup, Sven; Oberg, Fredrik Kryh; Vernet, Erik; Sandrini, Michael Paolo Bastner; Shaw, Allan Christian; Jessen, Carsten; Gronborg, Mads; Hald, Jacob; Willenbrock, Hanni; Madsen, Dennis; Wernersson, Rasmus; Hansson, Lena; Jensen, Jan Nygaard; Plesner, Annette; Alanentalo, Tomas; Petersen, Maja Borup Kjaer; Grapin-Botton, Anne; Honore, Christian; Ahnfelt-Ronne, Jonas; Hecksher-Sorensen, Jacob; Ravassard, Philippe; Madsen, Ole D.; Rescan, Claude; Frogne, Thomas

Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

DEVELOPMENT

IF3.6

2018-01-01

OAAI

Ramond, Cyrille; Beydag-Tasoz, Belin Selcen; Azad, Ajuna; van de Bunt, Martijn; Petersen, Maja Borup Kjaer; Beer, Nicola L.; Glaser, Nicolas; Berthault, Claire; Gloyn, Anna L.; Hansson, Mattias; McCarthy, Mark, I; Honore, Christian; Grapin-Botton, Anne; Scharfmann, Raphael

研究方向