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A

Antonio Ramos-Montoya

AstraZeneca
H指数:28
被引数:3,481

个人简介

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教育背景

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工作经历

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荣誉奖项

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Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity

蛋白质组指导的药物发现图谱并缓解治疗降解剂毒性

Nature Chemical Biology
IF13.7
2026-10-090
OAAI
Shaon Basu; Jason Shu Lim Yu; Jessica Bosak; Sharan K. Bagal; Claire Crafter; Charlene Fallan; Oliver Lemke; Anja Freiwald; Matthew E. H. White; Spyros I. Vernardis; Christoph B. Messner; Chrysiis Michaloglou; Kenneth Pryde; Antonio Ramos-Montoya; Sophie Regan; Monica Rodrigo-Brenni; Sascha Roth; Camilla Ruffilli; Michael Mülleder; Kevin Moreau; Markus Ralser
Discovery of AZD9750; an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
Journal of Medicinal Chemistry
IF6.8
2026-01-290
PRE
James S. Scott; Laura Evans; Peter C. Astles; Argyrides Argyrou; Sharan K. Bagal; David Beattie; Erin L. Braybrooke; Doyle J. Cassar; Claire Crafter; Coura Diène; Gary Fairley; Charlene Fallan; Graham Fraser; Nuria Galeano-Dalmau; Thomas G. Hammond; Andreas K. Hock; Thomas Jones; Jasper Komen; Gillian M. Lamont; Chrysiis Michaloglou; Michael J. Niedbala; Antonio Ramos-Montoya; Monica C. Rodrigo-Brenni; Martin J. Packer; Stuart Pearson; Andy Pike; Markus Schade; Joseph Shaw; Ziyanda Shologu; Oliver Steward
Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8H-purin-8-one Inhibitors of DNA-PK
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2022-07-076
OA
Goldberg, Frederick W.; Ting, Attilla K. T.; Beattie, David; Lamont, Gillian M.; Fallan, Charlene; Finlay, M. Raymond, V; Williamson, Beth; Schimpl, Marianne; Harmer, Alexander R.; Adeyemi, Oladipupo B.; Nordell, Par; Cronin, Anna S.; Vazquez-Chantada, Mercedes; Barratt, Derek; Ramos-Montoya, Antonio; Cadogan, Elaine B.; Davies, Barry R.
VEGF pathway inhibition potentiates PARP inhibitor efficacy in ovarian cancer independent of BRCA status

VEGF通路抑制增强PARP抑制剂在卵巢癌中的功效，而与BRCA状态无关

JOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
2021-11-0638
OAAI
Bizzaro, Francesca; Fuso Nerini, Ilaria; Taylor, Molly A.; Anastasia, Alessia; Russo, Massimo; Damia, Giovanna; Guffanti, Federica; Guana, Francesca; Ostano, Paola; Minoli, Lucia; Hattersley, Maureen M.; Arnold, Stephanie; Ramos-Montoya, Antonio; Williamson, Stuart C.; Galbiati, Alessandro; Urosevic, Jelena; Leo, Elisabetta; Cavallaro, Ugo; Ghilardi, Carmen; Barry, Simon T.; Bani, Maria Rosa; Giavazzi, Raffaella
Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-03-3011
OA
Carnevalli, Larissa S.; Taylor, Molly A.; King, Matthew; Coenen-Stass, Anna M. L.; Hughes, Adina M.; Bell, Sigourney; Proia, Theresa A.; Wang, Yanjun; Ramos-Montoya, Antonio; Wali, Neha; Carroll, Danielle; Singh, Maneesh; Moschetta, Michele; Gutierrez, Pablo Morentin; Gardelli, Cristina; Critchlow, Susan E.; Klinowska, Teresa; Fawell, Stephen E.; Barry, Simon T.
Independence of HIF1a and androgen signaling pathways in prostate cancer

前列腺癌中HIF1a与雄激素信号通路的独立性

BMC CANCER
IF3.4
2020-05-2528
OAAI
Tran, Maxine G. B.; Bibby, Becky A. S.; Yang, Lingjian; Lo, Franklin; Warren, Anne Y.; Shukla, Deepa; Osborne, Michelle; Hadfield, James; Carroll, Thomas; Stark, Rory; Scott, Helen; Ramos-Montoya, Antonio; Massie, Charlie; Maxwell, Patrick; West, Catharine M. L.; Mills, Ian G.; Neal, David E.
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-12-1863
OAAI
Goldberg, Frederick W.; Finlay, M. Raymond, V; Ting, Attilla K. T.; Beattie, David; Lamont, Gillian M.; Fallan, Charlene; Wrigley, Gail L.; Schimpl, Marianne; Howard, Martin R.; Williamson, Beth; Vazquez-Chantada, Mercedes; Barratt, Derek G.; Davies, Barry R.; Cadogan, Elaine B.; Ramos-Montoya, Antonio; Dean, Emma
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity
NATURE COMMUNICATIONS
IF15.7
2019-11-07237
OAAI
Fok, Jacqueline H. L.; Ramos-Montoya, Antonio; Vazquez-Chantada, Mercedes; Wijnhoven, Paul W. G.; Follia, Valeria; James, Neil; Farrington, Paul M.; Karmokar, Ankur; Willis, Sophie E.; Cairns, Jonathan; Nikkila, Jenni; Beattie, David; Lamont, Gillian M.; Finlay, M. Raymond, V; Wilson, Joanne; Smith, Aaron; O'Connor, Lenka Oplustil; Ling, Stephanie; Fawell, Stephen E.; O'Connor, Mark J.; Hollingsworth, Simon J.; Dean, Emma; Goldberg, Frederick W.; Davies, Barry R.; Cadogan, Elaine B.
pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry
BRITISH JOURNAL OF CANCER
IF6.8
2018-11-0229
OAAI
Jones, Gemma N.; Rooney, Claire; Griffin, Nicola; Roudier, Martine; Young, Lucy A.; Garcia-Trinidad, Antonio; Hughes, Gareth D.; Whiteaker, Jeffrey R.; Wilson, Zena; Odedra, Rajesh; Zhao, Lei; Ivey, Richard G.; Howat, William J.; Harrington, Elizabeth A.; Barrett, J. Carl; Ramos-Montoya, Antonio; Lau, Alan; Paulovich, Amanda G.; Cadogan, Elaine B.; Pierce, Andrew J.

研究方向

暂未获取到该数据
D
David E. Neal
H 指数:123论文数:1,310被引数:6.7万
E
Elaine Cadogan
H 指数:26论文数:128被引数:2,860
I
Ian G. Mills
H 指数:68论文数:582被引数:2.9万
A
Anne Y. Warren
H 指数:67论文数:438被引数:2.8万
B
Barry R. Davies
H 指数:43论文数:374被引数:6,889
A
Alastair Lamb
H 指数:35论文数:244被引数:4,661
D
Dean, Emma
H 指数:0论文数:2被引数:0
M
Mercedes Vázquez–Chantada
H 指数:18论文数:60被引数:1,918
H
Hayley C. Whitaker
H 指数:49论文数:222被引数:2.0万
H
Helen Ross‐Adams
H 指数:21论文数:73被引数:2,481