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燕贞 封面图

燕贞 (Zhen Yan)

Jacobs School of Medicine and Biomedical Sciences

77H指数
262论文数
2.0W被引数
收录论文 143
发表时间
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Cognitive and synaptic impairment induced by deficiency of autism risk gene Smarcc2 and its rescue by histone deacetylase inhibition自闭症风险基因Smarcc2缺失诱导的认知和突触功能障碍及其通过组蛋白去乙酰化酶抑制的修复
errMolecular Psychiatry
IF10.1
err2026-08-26
err0
errOAAI
errPei Li; Siqi Men; Prachetas J. Patel; Komal Saleem; Ping Zhong; Kin Wai Tam; Jian Feng; Zhen Yan
err分享
err收藏
Reduced expression of Brain Expressed X-linked genes in Alzheimer's disease阿尔茨海默病中脑表达X连锁基因的表达降低
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2026-08-03
err0
PREAI
errLi Li; Eliana Kenner; Lei Wan; Zhen Yan; Jian Feng
err分享
err收藏
Epigenomic aberrations of histone methylation in prefrontal cortex of humans with mild cognitive impairment and Alzheimer's disease
errJournal of Alzheimer’s Disease
IF0
err2026-01-21
err0
PREAI
errPrachetas Jai Patel; Zhen Yan
err分享
err收藏
Epigenetic treatment of synaptic and behavioral deficits in Dyrk1a-mutant miceDyrk1a-mutant小鼠突触和行为缺陷的表观遗传治疗
errNeuropsychopharmacology
IF7.1
err2026-01-20
err0
errOAAI
errChih-Hung Lin; Mingjun Yu; Prachetas Jai Patel; Pei Li; Zhen Yan
err分享
err收藏
Impact of dietary transitions on overweight and obesity burden and future trends among Chinese adults膳食转变对中国成年人超重和肥胖负担及未来趋势的影响
errnpj Science of Food
IF7.8
err2025-11-21
err0
errOAAI
errPan Zhuang; Xiaohui Liu; Yang Ao; Zhen Yan; You Wu; Xuzhi Wan; Yin Li; Yuqi Wu; Yu Zhang; Jingjing Jiao
err分享
err收藏
Elevated SGK1 increases Tau phosphorylation and microtubule instability in Alzheimer’s patient-derived cortical neuronsSGK1的升高增加了阿尔茨海默病患者源性皮层神经元中Tau的磷酸化及微管的不稳定性。
errMolecular Psychiatry
IF10.1
err2025-09-08
err0
errOAAI
errKomal Saleem; Zichun Xiao; Binglin Zhu; Yong Ren; Zhen Yan; Jian Feng
err分享
err收藏
Histone demethylase PHF2 regulates inflammatory genes in Alzheimer’s disease组蛋白去甲基化酶PHF2调控阿尔茨海默病中的炎症基因
errMolecular Psychiatry
IF10.1
err2025-08-23
err0
errOAAI
errGuojun Yang; Yong Ren; Ping Zhong; Prechetas Jai Patel; Xiao-Qing Chen; Lei Wan; Young-Ho Lee; Komal Saleem; Jian Feng; Zhen Yan
err分享
err收藏
Synaptic Deficits in Adnp-Mutant Mice Are Ameliorated by Histone Demethylase LSD1 InhibitionADNP突变小鼠的突触缺陷可被组蛋白去甲基化酶LSD1抑制剂改善
errAutism Research
IF5.6
err2025-06-19
err0
PREAI
errChih-Hung Lin; Yong Ren; Kin Wai Tam; Megan Conrow-Graham; Zhen Yan
err分享
err收藏
Childhood socioeconomic position and cognitive aging in Europe: The role of depressive symptoms and loneliness童年社会经济地位与认知老化在欧洲：抑郁症状和孤独感的作用
errJOURNAL OF AFFECTIVE DISORDERS
IF4.9
err2025-05-26
err0
PREAI
errHuang, Ruixue; Zou, Huiyun; Yan, Zhen; Wu, Weidong
err分享
err收藏
Low dietary intake of marine n-3 fatty acids and seafood significantly contributes to metabolic syndrome burden in China低海洋n-3脂肪酸和海产品的膳食摄入量显著增加了中国的代谢综合征负担。
errNutrition Research
IF3.1
err2025-05-02
err0
PREAI
errXiao Tang; Pan Zhuang; Suhua Wu; Xiaohui Liu; Xionghai Lu; You Wu; Zhen Yan; Yin Li; Yu Zhang; Jingjing Jiao
err分享
err收藏
Generation of human induced pluripotent stem cell-derived cortical neurons expressing the six tau isoforms
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2025-04-01
err0
PREAI
errJiang, Houbo; Xiao, Zichun; Saleem, Komal; Zhong, Ping; Li, Li; Chhetri, Gaurav; Li, Pei; Jiang, Zhongjiao; Yan, Zhen; Feng, Jian
err分享
err收藏
CRISPR-based epigenetic editing of Gad1 improves synaptic inhibition and cognitive behavior in a Tauopathy mouse model
errNEUROBIOLOGY OF DISEASE
IF5.6
err2025-03-01
err1
errOAAI
errWan, Lei; Zhong, Ping; Li, Pei; Ren, Yong; Wang, Wei; Yu, Mingjun; Feng, Henry Y.; Yan, Zhen
err分享
err收藏
Targeting epigenetic enzymes for autism treatment
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2024-09-01
err0
PREAI
errYan, Zhen
err分享
err收藏
Identification of a molecular network regulated by multiple ASD high risk genes
errHUMAN MOLECULAR GENETICS
IF3.2
err2024-04-08
err1
PREAI
errWan, Lei; Yang, Guojun; Yan, Zhen
err分享
err收藏
Distinct and Convergent Alterations of Entorhinal Cortical Circuits in Two Mouse Models for Alzheimer's Disease and Related Disorders
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2024-03-14
err0
errOAAI
errZhong, Ping; Cao, Qing; Yan, Zhen
err分享
err收藏
An epigenetic mechanism of social isolation stress in adolescent female mice
errNEUROBIOLOGY OF STRESS
IF3.6
err2024-03-01
err2
errOAAI
errLi, Pei; Yan, Zhen
err分享
err收藏
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophySNF8中的双等位基因变体引起的疾病谱从严重的发育性和癫痫性脑病到综合征性视神经萎缩
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2024-03-01
err4
errOAAI
errBrugger, Melanie; Lauri, Antonella; Zhen, Yan; Gramegna, Laura L.; Zott, Benedikt; Sekulic, Nikolina; Fasano, Giulia; Kopajtich, Robert; Cordeddu, Viviana; Radio, Francesca Clementina; Mancini, Cecilia; Pizzi, Simone; Paradisi, Graziamaria; Zanni, Ginevra; Vasco, Gessica; Carrozzo, Rosalba; Palombo, Flavia; Tonon, Caterina; Lodi, Raffaele; Morgia, Chiara La; Arelin, Maria; Blechschmidt, Cristiane; Finck, Tom; Sorensen, Vigdis; Kreiser, Kornelia; Strobl-Wildemann, Gertrud; Daum, Hagit; Michaelson-Cohen, Rachel; Ziccardi, Lucia; Zampino, Giuseppe; Prokisch, Holger; Jamra, Rami Abou; Fiorini, Claudio; Arzberger, Thomas; Winkelmann, Juliane; Caporali, Leonardo; Carelli, Valerio; Stenmark, Harald; Tartaglia, Marco; Wagner, Matias
err分享
err收藏
PTBP2 attenuation facilitates fibroblast to neuron conversion by promoting alternative splicing of neuronal genes
errSTEM CELL REPORTS
IF5.1
err2023-11-01
err2
errOAAI
errZhu, Binglin; Fisher, Emily; Li, Li; Zhong, Ping; Yan, Zhen; Feng, Jian
err分享
err收藏
Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization
errNEUROBIOLOGY OF DISEASE
IF5.6
err2023-08-01
err9
errOAAI
errPatel, Prachetas J.; Ren, Yong; Yan, Zhen
err分享
err收藏
Parkin Maintains Robust Pacemaking in Human Induced Pluripotent Stem Cell-Derived A9 Dopaminergic NeuronsParkin在人类诱导的多能干细胞衍生的A9多巴胺能神经元中保持稳健的起搏
errMOVEMENT DISORDERS
IF7.6
err2023-05-11
err1
PREAI
errPu, Jiali; Lin, Lin; Jiang, Houbo; Hu, Zhixing; Li, Hong; Yan, Zhen; Zhang, Baorong; Feng, Jian
err分享
err收藏

研究方向

环境与健康
合作学者
合作期刊
B
Bruce S. McEwen
H 指数: 221 · 论文数: 1.3K
P
Paul Greengard
H 指数: 206 · 论文数: 1.1K
R
Richard L. Huganir
H 指数: 145 · 论文数: 490
M
Morgan Sheng
H 指数: 141 · 论文数: 365
J
Joseph D. Buxbaum
H 指数: 140 · 论文数: 792
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