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S

Stefan G. Sarafianos

Emory University School of Medicine

58H指数
281论文数
1.2W被引数
收录论文 148
发表时间
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Inside Front Cover: Breakthrough Design of Highly Potent Antivirals Against Wild-Type HIV-1 and Lenacapavir-Resistant M66I Variant封面内页：针对野生型HIV-1和Lenacapavir抗性M66I变异体的强效抗病毒药物突破性设计
errAngewandte Chemie-International Edition
IF16.9
err2026-10-07
err0
errOAAI
errNicolas Jamey; D. M. Nirosh Udayanga; Huanchun Zhang; Roshan Katekar; Wei Xie; Shreya M. Ravichandran; Zachary C. Lorson; William M. McFadden; Won Hee Ryu; Jiashu; Karen A. Kirby; Stefan G. Sarafianos; Zhengqiang Wang
err分享
err收藏
Discovery of a 4′-Azido Fleximer Nucleoside Analog With Broad-Spectrum Antiviral Activity Against DENV, EBOV, and Other RNA Viruses发现一种具有广谱抗病毒活性的4′-叠氮基柔性核苷类似物，可对抗登革热病毒、埃博拉病毒及其他RNA病毒
errChemMedChem
IF3.4
err2026-09-08
err0
PREAI
errKyle A. Davis; Ryan L. Slack; Thomas R. Foulkes; Tereza Frčková; Lenka Tomková; Jessica L. Smith; Meareg Amare; Grayson D. Pipher; Peter Halfmann; Alec J. Hirsch; Luděk Eyer; Stefan G. Sarafianos; Katherine L. Seley-Radtke
err分享
err收藏
Breakthrough Design of Highly Potent Antivirals Against Wild-Type HIV-1 and Lenacapavir-Resistant M66I Variant突破性设计：针对野生型HIV-1和Lenacapavir耐药性M66I变体的高效抗病毒药物
errAngewandte Chemie-International Edition
IF16.9
err2026-08-28
err0
errOAAI
errNicolas Jamey; D. M. Nirosh Udayanga; Huanchun Zhang; Roshan Katekar; Wei Xie; Shreya M. Ravichandran; Xinyong Cai; Zachary C. Lorson; William M. McFadden; Won Hee Ryu; Jiashu Xie; Karen A. Kirby; Stefan G. Sarafianos; Zhengqiang Wang
err分享
err收藏
Catching our breath: development of interventions and therapies for respiratory syncytial virus抓住我们的呼吸：呼吸道合胞病毒干预措施和治疗方法的开发
errMicrobiology and Molecular Biology Reviews
IF7.8
err2026-01-01
err0
PREAI
errMathew, Asha Maria; Neilsen, Grace; Lan, Shuiyun; Shooter, Savannah Leanne; Zheng, Jeffrey Shi Jie; Estes, Jeremy; Cao, Dongdong; Schinazi, Raymond F.; Singh, Uma S.; Liang, Bo; Lee, Sujin; Sarafianos, Stefan G.
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Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents新型二聚体衣壳组装调节剂作为一类独特的强效抗HBV药物
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errAmblard, Franck; Chen, Zhe; Kra, Kalouna; Patel, Dharmeshkumar; Bassit, Leda; Gargowitsch, Laetitia; Degrouard, Jeril; Rat, Virgile; Arteni, Ana-Andreea; Matthews, Lauren; Ravichandran, Shreya M.; Jiang, Alfred; Athanasiadis, Antonis; Dangas, Georgios; Abate, Maedot; Tresset, Guillaume; Pronost, Julien; Salman, Mohammad; Verma, Kiran; Kirby, Karen A.; Michailidis, Eleftherios; de Rocquigny, Hugues; Durantel, David; Bressanelli, Stephane; Sarafianos, Stefan G.; Schinazi, Raymond F.
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Monkeypox Virus Is Inhibited by Nucleoside Analogues Including the Acyclic Phosphonates Adefovir and Tenofovir In Vitro猴痘病毒被核苷类似物（包括环状磷酸盐阿德福韦和替诺福韦）在体外抑制
errJournal of Medical Virology
IF4.6
err2025-10-25
err0
PREAI
errJasper Lee; Huanchun Zhang; Emerson Ailidh Boggs; Jesse Kilcullen; Margaret Moriarty; Yuhong Du; Haian Fu; Shuiyun Lan; Christina L. Hutson; Panayampalli S. Satheshkumar; Philip R. Tedbury; Stefan G. Sarafianos
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Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis针对衣壳靶向抗逆转录病毒药物在暴露前预防中的考量
errTrends in Molecular Medicine
IF13.8
err2025-02-27
err0
PREAI
errWilliam M. McFadden; Mia Faerch; Karen A. Kirby; Robert A. Dick; Bruce E. Torbett; Stefan G. Sarafianos
err分享
err收藏
Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles
errMBIO
IF4.7
err2024-12-11
err0
errOAAI
errNeilsen, Grace; Mathew, Asha Maria; Castro, Jose M.; Mcfadden, William M.; Wen, Xin; Ong, Yee T.; Tedbury, Philip R.; Lan, Shuiyun; Sarafianos, Stefan G.
err分享
err收藏
Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-10-08
err2
errOAAI
errAkaberi, Dario; Lati, Monireh Pourghasemi; Krambrich, Janina; Berger, Julia; Neilsen, Grace; Strandback, Emilia; Turunen, S. Pauliina; Wannberg, Johan; Gullberg, Hjalmar; Moche, Martin; Chinthakindi, Praveen Kumar; Nyman, Tomas; Sarafianos, Stefan G.; Sandstrom, Anja; Jarhult, Josef D.; Sandberg, Kristian; Lundkvist, Ake; Verho, Oscar; Lennerstrand, Johan
err分享
err收藏
HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-09-11
err0
errOAAI
errJang, Sooin; Bedwell, Gregory J.; Singh, Satya P.; Yu, Hyun Jae; Arnarson, Bjarki; Singh, Parmit K.; Radhakrishnan, Rajalingam; Douglas, AidanDarian W.; Ingram, Zachary M.; Freniere, Christian; Akkermans, Onno; Sarafianos, Stefan G.; Ambrose, Zandrea; Xiong, Yong; Anekal, Praju, V; Montero Llopis, Paula; Kewalramani, Vineet N.; Francis, Ashwanth C.; Engelman, Alan N.
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Myrtus communis L. Essential Oil Exhibits Antiviral Activity against CoronavirusesMyrtus communis L.精油对冠状病毒具有抗病毒活性
errPHARMACEUTICALS
IF4.8
err2024-09-10
err0
errOAAI
errLi, Dar-Yin; Donadu, Matthew G.; Shue, Taylor; Dangas, Georgios; Athanasiadis, Antonis; Lan, Shuiyun; Wen, Xin; Battah, Basem; Zanetti, Stefania; Mazzarello, Vittorio; Sarafianos, Stefan G.; Ferrari, Marco; Michailidis, Eleftherios
err分享
err收藏
A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries用于合成和筛选环肽库的无标签平台
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-04-17
err4
errOAAI
errBruce, Angele; Adebomi, Victor; Czabala, Patrick; Palmer, Jonathan; McFadden, William M.; Lorson, Zachary C.; Slack, Ryan L.; Bhardwaj, Gaurav; Sarafianos, Stefan G.; Raj, Monika
err分享
err收藏
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err4
PREAI
errAmblard, Franck; Lecher, Julia C.; De, Ramyani; Zhou, Shaoman; Liu, Peng; Goh, Shu Ling; Tao, Sijia; Patel, Dharmeshkumar; Downs-Bowen, Jessica; Zandi, Keivan; Zhang, Huanchun; Chaudhry, Gitika; McBrayer, Tamara; Muczynski, Michael; Al-Homoudi, Abdullah; Engel, Joseph; Lan, Shuiyun; Sarafianos, Stefan G.; Kovari, Ladislau C.; Schinazi, Raymond F.
err分享
err收藏
Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-03-01
err6
errOAAI
errMcfadden, William M.; Casey-Moore, Mary C.; Bare, Grant A. L.; Kirby, Karen A.; Wen, Xin; Li, Gencheng; Wang, Hua; Slack, Ryan L.; Snyder, Alexa A.; Lorson, Zachary C.; Kaufman, Isabella L.; Cilento, Maria E.; Tedbury, Philip R.; Gembicky, Milan; Olson, Arthur J.; Torbett, Bruce E.; Sharpless, Barry; Sarafianos, Stefan G.
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err收藏
HIV-2 inhibits HIV-1 gene expression via two independent mechanisms during cellular co-infection
errJOURNAL OF VIROLOGY
IF3.8
err2023-12-21
err2
errOAAI
errYapo, Vincent; Majumder, Kinjal; Tedbury, Philip R.; Wen, Xin; Ong, Yee T.; Johnson, Marc C.; Sarafianos, Stefan G.
err分享
err收藏
HIV-1 Resistance to Islatravir/Tenofovir Combination Therapy in Wild-Type or NRTI-Resistant Strains of Diverse HIV-1 Subtypes
errVIRUSES-BASEL
IF3.5
err2023-09-25
err4
errOAAI
errCilento, Maria E.; Wen, Xin; Reeve, Aaron B.; Ukah, Obiaara B.; Snyder, Alexa A.; Carrillo, Ciro M.; Smith, Cole P.; Edwards, Kristin; Wahoski, Claudia C.; Kitzler, Deborah R.; Kodama, Eiichi N.; Mitsuya, Hiroaki; Parniak, Michael A.; Tedbury, Philip R.; Sarafianos, Stefan G.
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err收藏
Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization
errNATURE COMMUNICATIONS
IF15.7
err2023-09-12
err6
errOAAI
errGres, Anna T.; Kirby, Karen A.; Mcfadden, William M.; Du, Haijuan; Liu, Dandan; Xu, Chaoyi; Bryer, Alexander J.; Perilla, Juan R.; Shi, Jiong; Aiken, Christopher; Fu, Xiaofeng; Zhang, Peijun; Francis, Ashwanth C.; Melikyan, Gregory B.; Sarafianos, Stefan G.
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err收藏
The HIV-1 capsid core is an opportunistic nuclear import receptor
errNATURE COMMUNICATIONS
IF15.7
err2023-06-24
err18
errOAAI
errXue, Guangai; Yu, Hyun Jae; Buffone, Cindy; Huang, Szu-Wei; Lee, KyeongEun; Goh, Shih Lin; Gres, Anna T. T.; Guney, Mehmet Hakan; Sarafianos, Stefan G. G.; Luban, Jeremy; Diaz-Griffero, Felipe; KewalRamani, Vineet N. N.
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err收藏
Mechanisms of Action of the Host-Targeting Agent Cyclosporin A and Direct-Acting Antiviral Agents against Hepatitis C Virus宿主靶向剂环孢菌素A和直接作用抗病毒剂对丙型肝炎病毒的作用机制
errVIRUSES-BASEL
IF3.5
err2023-04-17
err3
errOAAI
errLiu, Dandan; Ndongwe, Tanya P.; Ji, Juan; Huber, Andrew D.; Michailidis, Eleftherios; Rice, Charles M.; Ralston, Robert; Tedbury, Philip R.; Sarafianos, Stefan G.
err分享
err收藏
Targeting the HIV-1 and HBV Capsids, an EnCore
errVIRUSES-BASEL
IF3.5
err2023-03-31
err4
errOAAI
errMcFadden, William M.; Sarafianos, Stefan G.
err分享
err收藏

研究方向

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合作学者
合作期刊
C
Charles M. Rice
H 指数: 166 · 论文数: 718
K
Krzysztof Palczewski
H 指数: 115 · 论文数: 737
M
Mignon L. Loh
H 指数: 101 · 论文数: 901
S
Stephen P. Goff
H 指数: 95 · 论文数: 343
A
Alasdair C. Steven
H 指数: 95 · 论文数: 424
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