Alfred Ayala - Publications, H-index & Citations

Alfred Ayala

lifespan health rhode island

80H指数

538论文数

2.2W被引数

收录论文 121

发表时间

VISTA mediated anti-inflammatory function in monocyte-derived macrophages for treatment of septic ARDS

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Garcia, Fernando Gutierrez; Chen, Yaping; Ayala, Alfred

Predicting nonsense-mediated mRNA decay from splicing events in sepsis using RNA-sequencing data 利用RNA测序数据，根据脓毒症中的剪接事件预测无意义介导的mRNA降解

LIFE SCIENCE ALLIANCE

IF2.9

2025-09-24

OAAI

Shin, Jaewook; Fredericks, Alger M.; Armstead, Brandon E.; Ayala, Alfred; Cohen, Maya; Fairbrother, William G.; Levy, Mitchell M.; Lillard, Kwesi K.; Raggi, Emanuele; Nau, Gerard J.; Monaghan, Sean F.

Mechanisms of immune suppression in sepsis/shock: one investigator's/lab group's experience (SLB 2024 legacy award presentation)脓毒症/休克中免疫抑制的机制：一位研究者/实验室团队的经验（SLB 2024 继承奖演讲）

Journal of Leukocyte Biology

IF3.1

2025-07-24

PREAI

Alfred Ayala

Value of animal sepsis research in navigating the translational labyrinth 动物脓毒症研究的价值：在转化医学迷宫中的导航

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-04-15

OAAI

Wang, Haichao; Ayala, Alfred; Aziz, Monowar; Billiar, Timothy R.; Deutschman, Clifford S.; Jeyaseelan, Samithamby; Tang, Daolin; Wang, Ping

Herpes virus entry mediator signaling blockade produces mortality in neonatal sepsis through induced cardiac dysfunction

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-05-07

OAAI

Wakeley, Michelle E.; Denning, Naomi-Liza; Jiang, Jihong; De Paepe, Monique E.; Chung, Chun-Shiang; Wang, Ping; Ayala, Alfred

VISTA nonredundantly regulates proliferation and CD69low γδ T cell accumulation in the intestine in murine sepsis

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2023-11-30

PREAI

Gray, Chyna C.; Armstead, Brandon E.; Chung, Chun-Shiang; Chen, Yaping; Ayala, Alfred

Lymphocyte HVEM/BTLA co-expression after critical illness demonstrates severity indiscriminate upregulation, impacting critical illness-induced immunosuppression

FRONTIERS IN MEDICINE

IF3

2023-05-25

OAAI

Wakeley, Michelle E.; Armstead, Brandon E.; Gray, Chyna C.; Tindal, Elizabeth W.; Heffernan, Daithi S.; Chung, Chun-Shiang; Ayala, Alfred

Application of single cell multiomics points to changes in chromatin accessibility near calcitonin receptor like receptor and a possible role for adrenomedullin in the post-shock lung

FRONTIERS IN MEDICINE

IF3

2023-04-11

OAAI

Armstead, Brandon E.; Lee, Chung Sunny; Chen, Yaping; Zhao, Runping; Chung, Chun-Shiang; Fredericks, Alger M.; Monaghan, Sean F.; Ayala, Alfred

Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-12-16

OAAI

Fredericks, Alger M.; East, Kyle W.; Shi, Yuanjun; Liu, Jinchan; Maschietto, Federica; Ayala, Alfred; Cioffi, William G.; Cohen, Maya; Fairbrother, William G.; Lefort, Craig T.; Nau, Gerard J.; Levy, Mitchell M.; Wang, Jimin; Batista, Victor S.; Lisi, George P.; Monaghan, Sean F.

Deep RNA sequencing of intensive care unit patients with COVID-19

SCIENTIFIC REPORTS

IF3.9

2022-09-21

OAAI

Fredericks, Alger M.; Jentzsch, Maximilian S.; Cioffi, William G.; Cohen, Maya; Fairbrother, William G.; Gandhi, Shivam J.; Harrington, Elizabeth O.; Nau, Gerard J.; Reichner, Jonathan S.; Ventetuolo, Corey E.; Levy, Mitchell M.; Ayala, Alfred; Monaghan, Sean F.

The Neonatal Innate Immune Response to Sepsis: Checkpoint Proteins as Novel Mediators of This Response and as Possible Therapeutic/Diagnostic Levers

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-04

OAAI

Hensler, Emily; Petros, Habesha; Gray, Chyna C.; Chung, Chun-Shiang; Ayala, Alfred; Fallon, Eleanor A.

Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-03-24

OAAI

Gray, Chyna C.; Biron-Girard, Bethany; Wakeley, Michelle E.; Chung, Chun-Shiang; Chen, Yaping; Quiles-Ramirez, Yael; Tolbert, Jessica D.; Ayala, Alfred

Survival and Pulmonary Injury After Neonatal Sepsis: PD1/PDL1's Contributions to Mouse and Human Immunopathology

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-03-03

OAAI

Fallon, Eleanor A.; Chung, Chun-Shiang; Heffernan, Daithi S.; Chen, Yaping; De Paepe, Monique E.; Ayala, Alfred

SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model

MOLECULAR MEDICINE

IF6.4

2020-09-21

OAAI

Jiang, Jihong; Hu, Baoji; Chung, Chun-Shiang; Chen, Yaping; Zhang, Yunhe; Tindal, Elizabeth W.; Li, Jinbao; Ayala, Alfred

Blockade of endothelial, but not epithelial, cell expression of PD-L1 following severe shock attenuates the development of indirect acute lung injury in mice

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IF3.5

2020-04-01

OAAI

Xu, Shumin; Yang, Qian; Bai, Jianwen; Tao, Tianzhu; Tang, Lunxian; Chen, Yaping; Chung, Chun-Shiang; Fallon, Eleanor A.; Ayala, Alfred

Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-03-06

OAAI

Kotraiah, Vinayaka; Phares, Timothy W.; Browne, Cecille D.; Pannucci, James; Mansour, Marc; Noe, Amy R.; Tucker, Kenneth D.; Christen, Jayne M.; Reed, Charles; MacKay, Alecia; Weir, Genevieve M.; Rajagopalan, Rajkannan; Stanford, Marianne M.; Chung, Chun-Shiang; Ayala, Alfred; Huang, Jing; Tsuji, Moriya; Gutierrez, Gabriel M.

Alternative RNA splicing and alternative transcription start/end in acute respiratory distress syndrome

INTENSIVE CARE MEDICINE

IF21.2

2020-02-20

OAAI

Fredericks, Alger M.; Wang, Li Juan; Fairbrother, William G.; Ayala, Alfred; Monaghan, Sean F.

Check Point Inhibitors and Their Role in Immunosuppression in Sepsis

CRITICAL CARE CLINICS

IF2.4

2020-01-01

OAAI

Wakeley, Michelle E.; Gray, Chyna C.; Monaghan, Sean F.; Heffernan, Daithi S.; Ayala, Alfred

Blockade of equilibrative nucleoside transporter 1/2 protects against Pseudomonas aeruginosa-induced acute lung injury and NLRP3 inflammasome activation 阻断平衡核苷转运蛋白1/2可防止铜绿假单胞菌诱导的急性肺损伤和NLRP3炎性体激活

FASEB JOURNAL

IF4.2

2019-12-02

OAAI

Chambers, Eboni D.; White, Alexis; Vang, Alexander; Wang, Zhengke; Ayala, Alfred; Weng, Tingting; Blackburn, Michael; Choudhary, Gaurav; Rounds, Sharon; Lu, Qing

A novel role for programmed cell death receptor ligand 2 in sepsis-induced hepatic dysfunction

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

IF3.3

2019-01-01

OAAI

Rossi, Anne-Lise; Le, Marilyn; Chung, Chun-Shiang; Chen, Yaping; Fallon, Eleanor A.; Matoso, Andres; Xu, Shumin; Chun, Tristen T.; Erickson, Craig P.; Ayala, Alfred

研究方向