Amber K. L. Wezenaar - Publications, H-index & Citations

Amber K. L. Wezenaar

princess maxima center

4H指数

14论文数

330被引数

收录论文 12

发表时间

IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma IGSF11-VISTA是弥漫性中线胶质瘤的关键和可靶向的免疫检查点轴

Cancer Cell

IF44.5

2026-01-22

OAAI

Raphaël Collot; Cristian Ruiz-Moreno; Celina Honhoff; Thijs J.M. van den Broek; Amber K.L. Wezenaar; Daan J. Kloosterman; Hendrikus C.R. Ariese; Hannah Johnson; Britt M.T. Vervoort; Amal Jeiroshi; Jens Bunt; Ravian L. van Ineveld; Emma Bokobza; Heggert G. Rebel; Brigit M. te Pas; Femke C.A. Ringnalda; Marc van de Wetering; Pierre A. Robe; Marcel Kool; Jennifer R. Cochran

De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function 从头H3.3K27M-人类脑干类器官中改变的弥漫性中线胶质瘤，以解剖GD2 CAR T细胞功能

Nature Cancer

IF28.5

2026-01-05

OAAI

Nils Bessler; Amber K. L. Wezenaar; Hendrikus C. R. Ariese; Celina Honhoff; Noëlle Dommann; Ellen J. Wehrens; Cristian Ruiz Moreno; Thijs J. M. van den Broek; Raphaël V. U. Collot; Daan J. Kloosterman; Farid Keramati; Mieke Roosen; Sam de Blank; Esmée van Vliet; Mario Barrera Román; Lucrezia C. D. E. Gatti; Ali Ertürk; Jürgen Kuball; Zsolt Sebestyén; Marcel Kool; Sara Patrizi; Evelina Miele; Annette Künkele; Mariëtte E. G. Kranendonk; Annelisa M. Cornel; Stefan Nierkens; Christian Mayer; Hendrik G. Stunnenberg; Anna Alemany; Maria Alieva; Anne C. Rios

Modeling Pediatric DMG in Human BrOs (Brainstem-regionalized Organoids) Dissects Tumour-Microglia-Immune Crosstalk and CAR T Cell Dysfunction 在人类脑干区域性类器官（Human BrOs）中模拟儿童弥漫性中脑胶质瘤（Pediatric DMG），解析了肿瘤-小胶质细胞-免疫互作以及CAR T细胞功能障碍。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Bessler, Nils; Wezenaar, Amber K. L.; Ariese, Hendrikus C. R.; Honhoff, Celina; Wehrens, Ellen J.; Dommann, Noelle; Moreno, Cristian Ruiz; Van Den Broek, Thijs; Collot, Raphael V. U.; Kloosterman, Daan J.; Keramati, Farid; Roosen, Mieke; De Blank, Sam; Van Vliet, Esmee; Roman, Mario Barrera; Gatti, Lucrezia C. D. E.; Erturk, Ali; Kuball, Jurgen; Sebestyen, Zsolt; Kool, Marcel; Patrizi, Sara; Miele, Evelina; Kunkele, Annette; Kranendonk, Mariette E. G.; Cornel, Annelisa M.; Nierkens, Stefan; Mayer, Christian; Stunnenberg, Hendrik G.; Alemany, Anna; Alieva, Maria; Rios, Anne C.

JS07.7.A VISTA IS A CRITICAL AND TARGETABLE IMMUNE CHECKPOINT PATHWAY IN DIFFUSE MIDLINE GLIOMA JS07.7.A 视野是一种在弥漫性中线胶质瘤中具有关键性和可靶向性的免疫检查点通路

Neuro-Oncology

IF13.4

2025-10-03

OAAI

R Collot; C Ruiz-Moreno; C Honhoff; A K L Wezenaar; H C R Ariese; H Johnson; B M T Vervoort; J Bunt; E Bokobza; H G Rebel; B M te Pas; P A Robe; M Kool; M E G Kranendonk; D G van Vuurden; E Hulleman; E J Wehrens; A Zomer; H G Stunnenberg; A Rios

Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics 通过行为引导转录组学将T细胞动态映射到分子谱中

NATURE PROTOCOLS

IF16

2025-02-10

PREAI

Wezenaar, A. K. L.; Pandey, U.; Keramati, F.; Hernandez-Roca, M.; Brazda, P.; Roman, M. Barrera; Cleven, A.; Karaiskaki, F.; Aarts-Riemens, T.; de Blank, S.; Hernandez-Lopez, P.; Heijhuurs, S.; Alemany, A.; Kuball, J.; Sebestyen, Z.; Dekkers, J. F.; Stunnenberg, H. G.; Alieva, M.

Bridging live-cell imaging and next-generation cancer treatment 桥接活细胞成像和下一代癌症治疗

NATURE REVIEWS CANCER

IF66.8

2023-09-13

PREAI

Alieva, Maria; Wezenaar, Amber K. L.; Wehrens, Ellen J.; Rios, Anne C.

DISSECTING THE DIFFUSE MIDLINE GLIOMA TUMOUR MICROENVIRONMENT COMMUNICATIONS USING MULTIOMICS APPROACHES

NEURO-ONCOLOGY

IF13.4

2023-09-08

PREAI

Collot, R.; Moreno, C. Ruiz; Wezenaar, A.; Zomer, A.; Johnson, H.; Stunnenberg, H.; Rios, A.

INDUCTION AND TARGETING OF DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL

NEURO-ONCOLOGY

IF13.4

2023-09-08

OAAI

Bessler, N.; Moreno, C. Ruiz; Wezenaar, A.; Dommann, N.; Keramati, F.; Ariese, H. C. R.; Honhoff, C.; de Blank, S.; Roman, M. Barrera; Alieva, M.; Wehrens, E. J.; Alemany, A.; Stunnenberg, H. G.; Rios, A. C.

DISSECTING THE DIFFUSE MIDLINE GLIOMA TUMOR MICROENVIRONMENT COMMUNICATIONS USING MULTI-OMICS APPROACHES

NEURO-ONCOLOGY

IF13.4

2023-06-12

OAAI

Collot, Raphael; Moreno, Cristian Ruiz; Wezenaar, Amber; Zomer, Anoek; Johnson, Hannah; Stunnenberg, Henk; Rios, Anne

FROM NON-MALIGNANT TO MALIGNANT: GENERATING AND TARGETING DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL.

NEURO-ONCOLOGY

IF13.4

2023-06-12

OAAI

Bessler, Nils; Moreno, Cristian Ruiz; Wezenaar, Amber; Dommann, Noelle; Keramati, Farid; Ariese, Hendrikus C. R.; Honhoff, Celina; de Blank, Sam; Roman, Mario Barrera; Collot, Raphael; van Ineveld, Ravian; Krashennikova, Maria Alieva; Kranendonk, Mariette E. G.; Wehrens, Ellen J.; Alemany, Anna; Stunnenberg, Henk G.; Rios, Anne C.

Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma

NATURE COMMUNICATIONS

IF15.7

2023-05-27

OAAI

DeMartino, Jeff; Meister, Michael T.; Visser, Lindy L.; Brok, Mariel; Koerkamp, Marian J. A. Groot; Wezenaar, Amber K. L.; Hiemcke-Jiwa, Laura S.; de Souza, Terezinha; Merks, Johannes H. M.; Rios, Anne C.; Holstege, Frank C. P.; Margaritis, Thanasis; Drost, Jarno

Uncovering the mode of action of engineered T cells in patient cancer organoids 揭示工程改造的T细胞在患者癌症类器官中的作用方式

NATURE BIOTECHNOLOGY

IF41.7

2022-07-25

OAAI

Dekkers, Johanna F.; Alieva, Maria; Cleven, Astrid; Keramati, Farid; Wezenaar, Amber K. L.; van Vliet, Esmee J.; Puschhof, Jens; Brazda, Peter; Johanna, Inez; Meringa, Angelo D.; Rebel, Heggert G.; Buchholz, Maj-Britt; Roman, Mario Barrera; Zeeman, Amber L.; de Blank, Sam; Fasci, Domenico; Geurts, Maarten H.; Cornel, Annelisa M.; Driehuis, Else; Millen, Rosemary; Straetemans, Trudy; Nicolasen, Mara J. T.; Aarts-Riemens, Tineke; Ariese, Hendrikus C. R.; Johnson, Hannah R.; van Ineveld, Ravian L.; Karaiskaki, Froso; Kopper, Oded; Bar-Ephraim, Yotam E.; Kretzschmar, Kai; Eggermont, Alexander M. M.; Nierkens, Stefan; Wehrens, Ellen J.; Stunnenberg, Henk G.; Clevers, Hans; Kuball, Jurgen; Sebestyen, Zsolt; Rios, Anne C.

研究方向