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M

Mir-Farzin Mashreghi

german rheumatology research center
H指数:37
被引数:6,700

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Cytokine-mediated activation of kidney-infiltrating CD8+ T cells enables their contribution to inflammation in human lupus nephritis

细胞因子介导的肾脏浸润CD8+ T细胞激活使其能够参与人类狼疮肾炎的炎症过程

Science Translational Medicine
IF14.6
2026-07-080
PRE
Christopher M. Skopnik; Jan Klocke; Paul Freund; Diana Metzke; Lennard Ostendorf; Mario Bunse; Luka Prskalo; Johanna Kotzbauer; Christian Hinze; Emil Grothgar; Nina Goerlich; Leonie Wagner; Christoph Daniel; Arndt Hartmann; Udo Schneider; Robert Biesen; Tobias Alexander; Anja E. Hauser; Andreas Radbruch; Kai-Uwe Eckardt; Falk Hiepe; Andrey Kruglov; Mir-Farzin Mashreghi; Philipp Enghard
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation

他克莫司抵抗性调节性T细胞的临床开发以实现同时免疫抑制和免疫调节

MOLECULAR THERAPY ADVANCES
IF0
2026-05-012
OAAI
Zarrinrad, Ghazaleh; Burkhardt, Lisa-Marie; Beltran-Mestres, Claudia; Romero-Suarez, Silvina; Wagner, Dimitrios Laurin; Schlickeiser, Stephan; Stein, Maik; Wendering, Desiree Jacqueline; de la Cebosa, Ivan Juky Carrera Diaz; Ehlen, Lukas; Hamm, Frederik; Kurgan, Gavin L.; Durek, Pawel; Heinrich, Frederik; Giri, Anamika; Pu, Yaolin; Ou, Kristy; Hoffmann, Henrike; Muench, Sandra; Stuewe, Insa; Dolling, Sven; McCallion, Oliver; Kaeda, Jaspal; Kath, Jonas; Schulenberg, Sarah; Wiese, Niklas; Nazari, Abdolreza; Peter, Lena; Picht, Samira; Sanchez-Pena, Andrea; Usman, Olalekan; Brommel, Christian; Turk, Rolf; Rettig, Garrett; Sturgeon, Morgan; Osborne, Thomas L.; Jacobi, Ashley; Friedrich, Rebecca; Kaufmann, Masako Monika; Klermund, Julia; Fink, Simon; Templin, Markus F.; Roemhild, Andy; Kaiser, Daniel; Klein, Oliver; Cathomen, Toni; Mashreghi, Mir-Farzin; Issa, Fadi; Polansky, Julia K.; Volk, Hans-Dieter; Schmueck-Henneresse, Michael; Reinke, Petra; Amini, Leila
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial

Daratumumab治疗系统性红斑狼疮: 一项单臂2期试验

Nature Communications
IF15.7
2026-02-030
OAAI
Lennard Ostendorf; Jan Zernicke; Jens Klotsche; Robin Kempkens; Anne E. Beenken; Robert Biesen; Qingyu Cheng; Laleh Khodadadi; Gabriela Maria Guerra; Frederik Heinrich; Pawel Durek; Gerd-Rüdiger Burmester; Gerhard Krönke; Falk Hiepe; Mir-Farzin Mashreghi; Tobias Alexander
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs

肠神经系统来源的VIP抑制LGR5+干细胞向分泌谱系的分化，阻碍2型免疫程序。

Nature Immunology
IF27.6
2025-11-240
PRE
Manuel O. Jakob; Nele Sterczyk; Sotiria Boulekou; Patrycja M. Forster; Luisa Barleben; Nadra Alzain; Katja J. Jarick; Roksana M. Pirzgalska; Bruno Raposo; Karl Hansson; Elisabeth E. L. Nyström; Aurelia Gondrand; Miguel González-Acera; Pierre S. Leclère; Marlen S. Lapson; Sarah Poggenseier; Divija Deshpande; Laura Velleman; Tilman Breiderhoff; Max Felix Brunkhorst; Anton M. Schüle; Gabriela M. Guerra; Pawel Durek; Mir-Farzin Mashreghi; Anja A. Kühl; Coco Chu; Christoph Schneider; Carl Weidinger; Britta Siegmund; Thierry M. Nordmann; David Voehringer; Jay V. Patankar; Christoph Becker; George M. H. Birchenough; Henrique Veiga-Fernandes; Francesca Ronchi; Marina Kolesnichenko; Andreas Diefenbach; Christoph S. N. Klose
Two subsets of regulatory CD8+ T cells with differential transcriptome revealed by single cell analysis

通过单细胞分析揭示的具有差异转录组的两群调节性CD8+ T细胞。

iScience
IF4.1
2025-09-080
OAAI
Céline Sérazin; Lisa Dugast; Léa Flippe; Mathias Streitz; Désirée-Jacqueline Wendering; Stephan Schlickeiser; Frederik Heinrich; Pawel Durek; Gabriela Maria Guerra; Katrin Lehmann; Mir-Farzin Mashreghi; Harald Wajant; Hans Dieter Volk; Ignacio Anegon; Laurent David; Séverine Bézie; Carole Guillonneau
DNA methylomes undergo distinct waves of remodeling during thymic T cell development and do not acquire a proliferation-induced imprint

DNA甲基化组在胸腺T细胞发育过程中经历特定的重塑波，并且不会获得增殖诱导的印记。

Cell Reports
IF6.9
2025-08-020
OA
Frederik Hamm; Emilie Coppin; Mingxing Yang; Alisier Malard; Anne Schulze; Marcel Finke; Dania Hamo; Abdulrahman Salhab; Gilles Gasparoni; Jörn Walter; Mir-Farzin Mashreghi; Joachim Photiadis; Claudia Waskow; Julia K. Polansky
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis

Cineus, R.; Luo, Y.; Saliutina, M.; Manna, S.; Cancino, C.A.; Blazquez, L.V. IL-22-肿瘤坏死因子M轴促进肠道炎症和肿瘤发生。Nat. Immunol. 2025, 26, 837–853. [Google Scholar] [CrossRef]

Nature Immunology
IF27.6
2025-05-300
OAAI
Roodline Cineus; Yanjiang Luo; Mariia Saliutina; Subhakankha Manna; Camila A. Cancino; Luis Velasco Blázquez; Lifen Wang; Diana Bösel; Aya Abdelrahman; Joanna E. Klementowicz; Alexis Scherl; Saskia Hainbuch; Béatrice Bréart; Gino Kwon; Agata Konopka; Gabriela M. Guerra; Elena von Coburg; Lorenz Gerbeth; Juliette Roels; Frederik Heinrich; Nils Müller; Pawel Durek; Nikolaus Deigendesch; James Ziai; Jeffrey Hung; Thomas Conrad; Anja A. Kühl; Stefan Wirtz; Max Löhning; Mary Keir; Andreas Diefenbach; Mir-Farzin Mashreghi; Britta Siegmund; Michael Schumann; Chiara Romagnani; Nathaniel R. West; Ahmed N. Hegazy
Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn's disease

单细胞微生物组表型分析揭示了克罗恩病中与疾病和疗法相关的不同特征。

GUT MICROBES
IF11
2025-01-151
OAAI
Lisa Budzinski; Gi-Ung Kang; René Riedel; Toni Sempert; Leonie Lietz; René Maier; Janine Büttner; Bettina Bochow; Marcell T. Tordai; Aayushi Shah; Amro Abbas; Tanisha Momtaz; Jannike L. Krause; Robin Kempkens; Katrin Lehman; Gitta A. Heinz; Anne E. Benken; Stefanie Bartsch; Kathleen Necke; Ute Hoffmann; Mir-Farzin Mashreghi; Robert Biesen; Tilmann Kallinich; Tobias Alexander; Bosse Jessen; Carl Weidinger; Britta Siegmund; Andreas Radbruch; Anja Schirbel; Benjamin Moser; Hyun-Dong Chang
Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells
NATURE COMMUNICATIONS
IF15.7
2024-12-040
OAAI
Troch, Karoline F.; Jakob, Manuel O.; Forster, Patrycja M.; Jarick, Katja J.; Schreiber, Jonathan; Preusser, Alexandra; Guerra, Gabriela M.; Durek, Pawel; Tizian, Caroline; Sterczyk, Nele; Helfrich, Sofia; Duerr, Claudia U.; Voehringer, David; Witkowski, Mario; Artis, David; Rollenske, Tim; Kruglov, Andrey A.; Mashreghi, Mir-Farzin; Klose, Christoph S. N.
Effector memory-type regulatory T cells display phenotypic and functional instability
SCIENCE ADVANCES
IF12.5
2024-09-060
OAAI
Wendering, Desiree Jacqueline; Amini, Leila; Schlickeiser, Stephan; Farrera-Sal, Marti; Schulenberg, Sarah; Peter, Lena; Mai, Marco; Vollmer, Tino; Du, Weijie; Stein, Maik; Hamm, Frederik; Malard, Alisier; Castro, Carla; Yang, Mingxing; Ranka, Ramon; Rueckert, Timo; Durek, Pawel; Heinrich, Frederik; Gasparoni, Gilles; Salhab, Abdulrahman; Walter, Joern; Wagner, Dimitrios Laurin; Mashreghi, Mir-Farzin; Landwehr-Kenzel, Sybille; Polansky, Julia K.; Reinke, Petra; Volk, Hans-Dieter; Schmueck-Henneresse, Michael
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis (vol 20, pg 471, 2019)
NATURE IMMUNOLOGY
IF27.6
2024-05-231
OA
Neumann, Christian; Blume, Jonas; Roy, Urmi; Teh, Peggy P.; Vasanthakumar, Ajithkumar; Beller, Alexander; Liao, Yang; Heinrich, Frederik; Arenzana, Teresita L.; Hackney, Jason A.; Eidenschenk, Celine; Galvez, Eric J. C.; Stehle, Christina; Heinz, Gitta A.; Maschmeyer, Patrick; Sidwell, Tom; Hu, Yifang; Amsen, Derk; Romagnani, Chiara; Chang, Hyun-Dong; Kruglov, Andrey; Mashreghi, Mir-Farzin; Shi, Wei; Strowig, Till; Rutz, Sascha; Kallies, Axel; Scheffold, Alexander
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-05-233
OAAI
Roewekamp, Ivo; Maschirow, Laura; Rabes, Anne; Vernengo, Facundo Fiocca; Hamann, Lutz; Heinz, Gitta Anne; Mashreghi, Mir- Farzin; Caesar, Sandra; Milek, Miha; Fonseca, Anna Carolina Fagundes; Wienhold, Sandra - Maria; Nouailles, Geraldine; Yao, Ling; Mousavi, Soraya; Bruder, Dunja; Boehme, Julia D.; Puzianowska-Kuznicka, Monika; Beule, Dieter; Witzenrath, Martin; Loehning, Max; Klose, Christoph S. N.; Heimesaat, Markus M.; Diefenbach, Andreas; Opitz, Bastian
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow
NATURE COMMUNICATIONS
IF15.7
2024-05-171
OAAI
Ferreira-Gomes, Marta; Chen, Yidan; Durek, Pawel; Rincon-Arevalo, Hector; Heinrich, Frederik; Bauer, Laura; Szelinski, Franziska; Guerra, Gabriela Maria; Stefanski, Ana-Luisa; Niedobitek, Antonia; Wiedemann, Annika; Bondareva, Marina; Ritter, Jacob; Lehmann, Katrin; Hardt, Sebastian; Hipfl, Christian; Hein, Sascha; Hildt, Eberhard; Matz, Mareen; Mei, Henrik E.; Cheng, Qingyu; Dang, Van Duc; Witkowski, Mario; Lino, Andreia C.; Kruglov, Andrey; Melchers, Fritz; Perka, Carsten; Schrezenmeier, Eva V.; Hutloff, Andreas; Radbruch, Andreas; Doerner, Thomas; Mashreghi, Mir-Farzin
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung
NATURE COMMUNICATIONS
IF15.7
2024-03-301
OAAI
Doerner, Patrick J.; Anandakumar, Harithaa; Roewekamp, Ivo; Fiocca Vernengo, Facundo; Millet Pascual-Leone, Belen; Krzanowski, Marta; Sellmaier, Josua; Bruening, Ulrike; Fritsche-Guenther, Raphaela; Pfannkuch, Lennart; Kurth, Florian; Milek, Miha; Igbokwe, Vanessa; Loeber, Ulrike; Gutbier, Birgitt; Holstein, Markus; Heinz, Gitta Anne; Mashreghi, Mir-Farzin; Schulte, Leon N.; Klatt, Ann-Brit; Caesar, Sandra; Wienhold, Sandra-Maria; Offermanns, Stefan; Mack, Matthias; Witzenrath, Martin; Jordan, Stefan; Beule, Dieter; Kirwan, Jennifer A.; Forslund, Sofia K.; Wilck, Nicola; Bartolomaeus, Hendrik; Heimesaat, Markus M.; Opitz, Bastian
UNC93B1 variants underlie TLR7-dependent autoimmunity
SCIENCE IMMUNOLOGY
IF16.3
2024-02-2321
PRE
Wolf, Christine; Lim, Ee Lyn; Mokhtari, Mohammad; Kind, Barbara; Odainic, Alexandru; Lara-Villacanas, Eusebia; Koss, Sarah; Mages, Simon; Menzel, Katharina; Engel, Kerstin; Dueckers, Gregor; Bernbeck, Benedikt; Schneider, Dominik T.; Siepermann, Kathrin; Niehues, Tim; Goetzke, Carl Christoph; Durek, Pawel; Minden, Kirsten; Doerner, Thomas; Stittrich, Anna; Szelinski, Franziska; Guerra, Gabriela Maria; Massoud, Mona; Bieringer, Markus; Mann, Carina C. de Oliveira; Beltran, Eduardo; Kallinich, Tilmann; Mashreghi, Mir-Farzin; Schmidt, Susanne V.; Latz, Eicke; Klughammer, Johanna; Majer, Olivia; Lee-Kirsch, Min Ae

研究方向

暂未获取到该数据
A
Andreas Radbruch
H 指数:113论文数:752被引数:4.5万
P
Pawel Durek
H 指数:37论文数:135被引数:6,540
F
Frederik Heinrich
H 指数:27论文数:83被引数:3,569
H
Hyun‐Dong Chang
H 指数:43论文数:218被引数:9,273
G
Gitta Anne Heinz
H 指数:25论文数:68被引数:3,475
C
Claudia Haftmann
H 指数:20论文数:38被引数:3,331
R
René Riedel
H 指数:20论文数:63被引数:2,167
P
Patrick Maschmeyer
H 指数:19论文数:46被引数:1,225
A
Andrey Kruglov
H 指数:35论文数:151被引数:4,764
G
Gabriela Maria Guerra
H 指数:13论文数:47被引数:1,058