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F

Frederik Heinrich

humboldt university of berlin
H指数:27
被引数:3,569
浏览量:0

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Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation

他克莫司抵抗性调节性T细胞的临床开发以实现同时免疫抑制和免疫调节

MOLECULAR THERAPY ADVANCES
IF0
2026-05-012
OAAI
Zarrinrad, Ghazaleh; Burkhardt, Lisa-Marie; Beltran-Mestres, Claudia; Romero-Suarez, Silvina; Wagner, Dimitrios Laurin; Schlickeiser, Stephan; Stein, Maik; Wendering, Desiree Jacqueline; de la Cebosa, Ivan Juky Carrera Diaz; Ehlen, Lukas; Hamm, Frederik; Kurgan, Gavin L.; Durek, Pawel; Heinrich, Frederik; Giri, Anamika; Pu, Yaolin; Ou, Kristy; Hoffmann, Henrike; Muench, Sandra; Stuewe, Insa; Dolling, Sven; McCallion, Oliver; Kaeda, Jaspal; Kath, Jonas; Schulenberg, Sarah; Wiese, Niklas; Nazari, Abdolreza; Peter, Lena; Picht, Samira; Sanchez-Pena, Andrea; Usman, Olalekan; Brommel, Christian; Turk, Rolf; Rettig, Garrett; Sturgeon, Morgan; Osborne, Thomas L.; Jacobi, Ashley; Friedrich, Rebecca; Kaufmann, Masako Monika; Klermund, Julia; Fink, Simon; Templin, Markus F.; Roemhild, Andy; Kaiser, Daniel; Klein, Oliver; Cathomen, Toni; Mashreghi, Mir-Farzin; Issa, Fadi; Polansky, Julia K.; Volk, Hans-Dieter; Schmueck-Henneresse, Michael; Reinke, Petra; Amini, Leila
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial

Daratumumab治疗系统性红斑狼疮: 一项单臂2期试验

Nature Communications
IF15.7
2026-02-030
OAAI
Lennard Ostendorf; Jan Zernicke; Jens Klotsche; Robin Kempkens; Anne E. Beenken; Robert Biesen; Qingyu Cheng; Laleh Khodadadi; Gabriela Maria Guerra; Frederik Heinrich; Pawel Durek; Gerd-Rüdiger Burmester; Gerhard Krönke; Falk Hiepe; Mir-Farzin Mashreghi; Tobias Alexander
Two subsets of regulatory CD8+ T cells with differential transcriptome revealed by single cell analysis

通过单细胞分析揭示的具有差异转录组的两群调节性CD8+ T细胞。

iScience
IF4.1
2025-09-080
OAAI
Céline Sérazin; Lisa Dugast; Léa Flippe; Mathias Streitz; Désirée-Jacqueline Wendering; Stephan Schlickeiser; Frederik Heinrich; Pawel Durek; Gabriela Maria Guerra; Katrin Lehmann; Mir-Farzin Mashreghi; Harald Wajant; Hans Dieter Volk; Ignacio Anegon; Laurent David; Séverine Bézie; Carole Guillonneau
Effects of CRISPR-Cas9-mediated FOXP3 knockout on CAR T-cell potency

CRISPR-Cas9介导的FOXP3基因敲除对CAR T细胞效力的影响

Molecular Therapy Methods & Clinical Development
IF4.7
2025-08-210
OAAI
Lena Peter; Martí Farrera-Sal; Ferhat Ali Yaman; Nils Henrik Dempewolf; Samira Picht; Sarah Schulenberg; Jonas Kath; Frederik Hamm; Frederik Heinrich; Dimitrios L. Wagner; Mir-Farzin Mashreghi; Annette Künkele; Petra Reinke; Julia K. Polánsky; Michael Schmueck-Henneresse
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis

Cineus, R.; Luo, Y.; Saliutina, M.; Manna, S.; Cancino, C.A.; Blazquez, L.V. IL-22-肿瘤坏死因子M轴促进肠道炎症和肿瘤发生。Nat. Immunol. 2025, 26, 837–853. [Google Scholar] [CrossRef]

Nature Immunology
IF27.6
2025-05-300
OA
Roodline Cineus; Yanjiang Luo; Mariia Saliutina; Subhakankha Manna; Camila A. Cancino; Luis Velasco Blázquez; Lifen Wang; Diana Bösel; Aya Abdelrahman; Joanna E. Klementowicz; Alexis Scherl; Saskia Hainbuch; Béatrice Bréart; Gino Kwon; Agata Konopka; Gabriela M. Guerra; Elena von Coburg; Lorenz Gerbeth; Juliette Roels; Frederik Heinrich; Nils Müller; Pawel Durek; Nikolaus Deigendesch; James Ziai; Jeffrey Hung; Thomas Conrad; Anja A. Kühl; Stefan Wirtz; Max Löhning; Mary Keir; Andreas Diefenbach; Mir-Farzin Mashreghi; Britta Siegmund; Michael Schumann; Chiara Romagnani; Nathaniel R. West; Ahmed N. Hegazy
TGFβ links EBV to multisystem inflammatory syndrome in children

TGFβ将EBV与儿童多系统炎症综合征联系起来

NATURE
IF48.5
2025-03-121
OA
Goetzke, Carl Christoph; Massoud, Mona; Frischbutter, Stefan; Guerra, Gabriela Maria; Ferreira-Gomes, Marta; Heinrich, Frederik; von Stuckrad, Anne Sae Lim; Wisniewski, Sebastian; Licha, Jan Robin; Bondareva, Marina; Ehlers, Lisa; Khaldi-Plassart, Samira; Javouhey, Etienne; Pons, Sylvie; Trouillet-Assant, Sophie; Ozsurekci, Yasemin; Zhang, Yu; Poli, Maria Cecilia; Discepolo, Valentina; Lo Vecchio, Andrea; Sahin, Bengue; Verboom, Murielle; Hallensleben, Michael; Heuhsen, Anja Isabelle; Astudillo, Camila; Espinosa, Yazmin; Vial Cox, Maria Cecilia; Dobbs, Kerry; Delmonte, Ottavia M.; Montealegre Sanchez, Gina A.; Magliocco, Mary; Barron, Karyl; Danielson, Jeffrey; Petrov, Lev; Unterwalder, Nadine; Sawitzki, Birgit; Matz, Mareen; Lehmann, Katrin; Gratopp, Alexander; von Bernuth, Horst; Burkhardt, Lisa-Marie; Wiese, Niklas; Peter, Lena; Amini, Leila; Roehmel, Jobst Fridolin; Gewurz, Benjamin E.; Yonker, Lael M.; Witkowski, Mario; Kruglov, Andrey; Mall, Marcus Alexander; Su, Helen C.; Ozen, Seza; Radbruch, Andreas; Belot, Alexandre; Durek, Pawel; Kallinich, Tilmann; Mashreghi, Mir-Farzin
Effector memory-type regulatory T cells display phenotypic and functional instability
SCIENCE ADVANCES
IF12.5
2024-09-060
OAAI
Wendering, Desiree Jacqueline; Amini, Leila; Schlickeiser, Stephan; Farrera-Sal, Marti; Schulenberg, Sarah; Peter, Lena; Mai, Marco; Vollmer, Tino; Du, Weijie; Stein, Maik; Hamm, Frederik; Malard, Alisier; Castro, Carla; Yang, Mingxing; Ranka, Ramon; Rueckert, Timo; Durek, Pawel; Heinrich, Frederik; Gasparoni, Gilles; Salhab, Abdulrahman; Walter, Joern; Wagner, Dimitrios Laurin; Mashreghi, Mir-Farzin; Landwehr-Kenzel, Sybille; Polansky, Julia K.; Reinke, Petra; Volk, Hans-Dieter; Schmueck-Henneresse, Michael
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host-microbiota homeostasis (vol 20, pg 471, 2019)
NATURE IMMUNOLOGY
IF27.6
2024-05-231
OA
Neumann, Christian; Blume, Jonas; Roy, Urmi; Teh, Peggy P.; Vasanthakumar, Ajithkumar; Beller, Alexander; Liao, Yang; Heinrich, Frederik; Arenzana, Teresita L.; Hackney, Jason A.; Eidenschenk, Celine; Galvez, Eric J. C.; Stehle, Christina; Heinz, Gitta A.; Maschmeyer, Patrick; Sidwell, Tom; Hu, Yifang; Amsen, Derk; Romagnani, Chiara; Chang, Hyun-Dong; Kruglov, Andrey; Mashreghi, Mir-Farzin; Shi, Wei; Strowig, Till; Rutz, Sascha; Kallies, Axel; Scheffold, Alexander
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow
NATURE COMMUNICATIONS
IF15.7
2024-05-171
OAAI
Ferreira-Gomes, Marta; Chen, Yidan; Durek, Pawel; Rincon-Arevalo, Hector; Heinrich, Frederik; Bauer, Laura; Szelinski, Franziska; Guerra, Gabriela Maria; Stefanski, Ana-Luisa; Niedobitek, Antonia; Wiedemann, Annika; Bondareva, Marina; Ritter, Jacob; Lehmann, Katrin; Hardt, Sebastian; Hipfl, Christian; Hein, Sascha; Hildt, Eberhard; Matz, Mareen; Mei, Henrik E.; Cheng, Qingyu; Dang, Van Duc; Witkowski, Mario; Lino, Andreia C.; Kruglov, Andrey; Melchers, Fritz; Perka, Carsten; Schrezenmeier, Eva V.; Hutloff, Andreas; Radbruch, Andreas; Doerner, Thomas; Mashreghi, Mir-Farzin
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses
NATURE IMMUNOLOGY
IF27.6
2024-01-032
OAAI
Brunner, Tobias M.; Serve, Sebastian; Marx, Anna-Friederike; Fadejeva, Jelizaveta; Saikali, Philippe; Dzamukova, Maria; Duran-Hernandez, Nayar; Kommer, Christoph; Heinrich, Frederik; Durek, Pawel; Heinz, Gitta A.; Hoefer, Thomas; Mashreghi, Mir-Farzin; Kuehn, Ralf; Pinschewer, Daniel D.; Loehning, Max
NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age- related osteoarthritis

NOS抑制逆转TLR2-induced软骨细胞功能障碍并减轻年龄相关性骨关节炎

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-07-108
OAAI
Shen, Ping; Serve, Sebastian; Wu, Peihua; Liu, Xiaohui; Dai, Yujie; Duran-Hernandez, Nayar; Nguyen, Dan Thi Mai; Fuchs, Michael; Maleitzke, Tazio; Reisener, Marie-Jacqueline; Dzamukova, Maria; Nussbaumer, Katrin; Brunner, Tobias M.; Li, Yonghai; Holecska, Vivien; Heinz, Gitta A.; Heinrich, Frederik; Durek, Pawel; Katsoula, Georgia; Gwinner, Clemens; Jung, Tobias; Zeggini, Eleftheria; Winkler, Tobias; Mashreghi, Mir-Farzin; Pumberger, Matthias; Perka, Carsten; Lohning, Max
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
NATURE COMMUNICATIONS
IF15.7
2023-02-1121
OAAI
Mothes, Ronja; Pascual-Reguant, Anna; Koehler, Ralf; Liebeskind, Juliane; Liebheit, Alina; Bauherr, Sandy; Philipsen, Lars; Dittmayer, Carsten; Laue, Michael; von Manitius, Regina; Elezkurtaj, Sefer; Durek, Pawel; Heinrich, Frederik; Heinz, Gitta A.; Guerra, Gabriela M.; Obermayer, Benedikt; Meinhardt, Jenny; Ihlow, Jana; Radke, Josefine; Heppner, Frank L.; Enghard, Philipp; Stockmann, Helena; Aschman, Tom; Schneider, Julia; Corman, Victor M.; Sander, Leif E.; Mashreghi, Mir-Farzin; Conrad, Thomas; Hocke, Andreas C.; Niesner, Raluca A.; Radbruch, Helena; Hauser, Anja E.
Non-redundant functions of group 2 innate lymphoid cells
Nature
IF48.5
2022-11-020
PRE
Katja J. Jarick; Patrycja M. Topczewska; Manuel O. Jakob; Hiroshi Yano; Mohammad Arifuzzaman; Xuemei Gao; Sotiria Boulekou; Vladislava Stokic-Trtica; Pierre S. Leclère; Alexandra Preußer; Zoe A. Rompe; Anton Stamm; Amy M. Tsou; Coco Chu; Frederik R. Heinrich; Gabriela M. Guerra; Pawel Durek; Andranik Ivanov; Dieter Beule; Sofia Helfrich; Claudia U. Duerr; Anja A. Kühl; Christina Stehle; Chiara Romagnani; Mir-Farzin Mashreghi; Andreas Diefenbach; David Artis; Christoph S. N. Klose
Questioning whether IgM Fc receptor (FcμR) is expressed by innate immune cells

质疑IgM Fc受体 (Fc μ r) 是否由先天免疫细胞表达

NATURE COMMUNICATIONS
IF15.7
2022-07-114
OAAI
Skopnik, Christopher M.; Riedel, Rene; Addo, Richard K.; Heinz, Gitta Anne; Heinrich, Frederik; Honjo, Kazuhito; Durek, Pawel; Enghard, Philipp; Mashreghi, Mir-Farzin; Radbruch, Andreas; Kubagawa, Hiromi
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
NATURE COMMUNICATIONS
IF15.7
2022-06-0133
OAAI
Dzamukova, Maria; Brunner, Tobias M.; Miotla-Zarebska, Jadwiga; Heinrich, Frederik; Brylka, Laura; Mashreghi, Mir-Farzin; Kusumbe, Anjali; Kuehn, Ralf; Schinke, Thorsten; Vincent, Tonia L.; Loehning, Max
B Cell Numbers Predict Humoral and Cellular Response Upon SARS-CoV-2 Vaccination Among Patients Treated With Rituximab

B细胞数量可预测利妥昔单抗治疗患者SARS-CoV-2疫苗接种后的体液和细胞反应

ARTHRITIS & RHEUMATOLOGY
IF10.9
2022-04-1748
OA
Stefanski, Ana-Luisa; Rincon-Arevalo, Hector; Schrezenmeier, Eva; Karberg, Kirsten; Szelinski, Franziska; Ritter, Jacob; Jahrsdoerfer, Bernd; Schrezenmeier, Hubert; Ludwig, Carolin; Sattler, Arne; Kotsch, Katja; Chen, Yidan; Claussnitzer, Anne; Haibel, Hildrun; Proft, Fabian; Guerra, Gabriela; Durek, Pawel; Heinrich, Frederik; Ferreira-Gomes, Marta; Burmester, Gerd R.; Radbruch, Andreas; Mashreghi, Mir-Farzin; Lino, Andreia C.; Doerner, Thomas
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn′s disease patients
MUCOSAL IMMUNOLOGY
IF7.6
2022-03-0120
OAAI
Ahlers, Jonas; Mantei, Andrej; Lozza, Laura; Staeber, Manuela; Heinrich, Frederik; Bacher, Petra; Hohnstein, Thordis; Menzel, Lutz; Yuez, Simge G.; Alvarez-Simon, Daniel; Bickenbach, Anne Rieke; Weidinger, Carl; Mockel-Tenbrinck, Nadine; Kuehl, Anja A.; Siegmund, Britta; Maul, Jochen; Neumann, Christian; Scheffold, Alexander
Follicular Helper-like T Cells in the Lung Highlight a Novel Role of B Cells in Sarcoidosis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2021-12-1521
OAAI
Bauer, Laura; Mueller, Lisa Jasmin; Volkers, Sarah M.; Heinrich, Frederik; Mashreghi, Mir-Farzin; Ruppert, Clemens; Sander, Leif E.; Hutloff, Andreas
Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients

肾移植受者和透析患者对SARS-CoV-2 BNT162b2疫苗的体液免疫受损

SCIENCE IMMUNOLOGY
IF16.3
2021-06-15216
OA
Rincon-Arevalo, Hector; Choi, Mira; Stefanski, Ana-Luisa; Halleck, Fabian; Weber, Ulrike; Szelinski, Franziska; Jahrsdorfer, Bernd; Schrezenmeier, Hubert; Ludwig, Carolin; Sattler, Arne; Kotsch, Katja; Potekhin, Alexander; Chen, Yidan; Burmester, Gerd R.; Eckardt, Kai-Uwe; Guerra, Gabriela Maria; Durek, Pawel; Heinrich, Frederik; Ferreira-Gomes, Marta; Radbruch, Andreas; Budde, Klemens; Lino, Andreia C.; Mashreghi, Mir-Farzin; Schrezenmeier, Eva; Doerner, Thomas
Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint
OSTEOARTHRITIS AND CARTILAGE
IF9
2021-06-0112
OAAI
Sunkara, V; Heinz, G. A.; Heinrich, F. F.; Durek, P.; Mobasheri, A.; Mashreghi, M-F; Lang, A.

研究方向

暂未获取到该数据
M
Mir‐Farzin Mashreghi
H 指数:37论文数:191被引数:6,700
P
Pawel Durek
H 指数:37论文数:135被引数:6,540
G
Gitta Anne Heinz
H 指数:25论文数:68被引数:3,475
A
Andreas Radbruch
H 指数:113论文数:752被引数:4.5万
G
Gabriela Maria Guerra
H 指数:13论文数:47被引数:1,058
A
Andrey Kruglov
H 指数:35论文数:151被引数:4,764
A
Andreas Diefenbach
H 指数:63论文数:181被引数:3.4万
C
Chiara Romagnani
H 指数:50论文数:128被引数:1.0万
C
Christian Neumann
H 指数:21论文数:56被引数:1,755
M
Marta Ferreira‐Gomes
H 指数:12论文数:24被引数:1,266