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P

Pawel Durek

humboldt university of berlin
H指数:37
被引数:6,540
浏览量:0

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Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation

他克莫司抵抗性调节性T细胞的临床开发以实现同时免疫抑制和免疫调节

MOLECULAR THERAPY ADVANCES
IF0
2026-05-012
OAAI
Zarrinrad, Ghazaleh; Burkhardt, Lisa-Marie; Beltran-Mestres, Claudia; Romero-Suarez, Silvina; Wagner, Dimitrios Laurin; Schlickeiser, Stephan; Stein, Maik; Wendering, Desiree Jacqueline; de la Cebosa, Ivan Juky Carrera Diaz; Ehlen, Lukas; Hamm, Frederik; Kurgan, Gavin L.; Durek, Pawel; Heinrich, Frederik; Giri, Anamika; Pu, Yaolin; Ou, Kristy; Hoffmann, Henrike; Muench, Sandra; Stuewe, Insa; Dolling, Sven; McCallion, Oliver; Kaeda, Jaspal; Kath, Jonas; Schulenberg, Sarah; Wiese, Niklas; Nazari, Abdolreza; Peter, Lena; Picht, Samira; Sanchez-Pena, Andrea; Usman, Olalekan; Brommel, Christian; Turk, Rolf; Rettig, Garrett; Sturgeon, Morgan; Osborne, Thomas L.; Jacobi, Ashley; Friedrich, Rebecca; Kaufmann, Masako Monika; Klermund, Julia; Fink, Simon; Templin, Markus F.; Roemhild, Andy; Kaiser, Daniel; Klein, Oliver; Cathomen, Toni; Mashreghi, Mir-Farzin; Issa, Fadi; Polansky, Julia K.; Volk, Hans-Dieter; Schmueck-Henneresse, Michael; Reinke, Petra; Amini, Leila
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial

Daratumumab治疗系统性红斑狼疮: 一项单臂2期试验

Nature Communications
IF15.7
2026-02-030
OAAI
Lennard Ostendorf; Jan Zernicke; Jens Klotsche; Robin Kempkens; Anne E. Beenken; Robert Biesen; Qingyu Cheng; Laleh Khodadadi; Gabriela Maria Guerra; Frederik Heinrich; Pawel Durek; Gerd-Rüdiger Burmester; Gerhard Krönke; Falk Hiepe; Mir-Farzin Mashreghi; Tobias Alexander
Bronchiectasis and chronic active EBV (CAEBV) as first signs of IRF8-deficiency

支气管扩张和慢性活动性EBV（CAEBV）作为IRF8缺乏的首发症状

Klinische Padiatrie
IF0.9
2026-02-010
PRE
Voller, M.; Ham, H.; Mandry, M.; Kumanovics, A.; Knight, O.; Ehlers, L.; Zirngibl, F.; Ruckert, T.; Wittkowski, H.; Lentz, J.; Meisel, C.; Unterwalder, N.; Dinges, S.; Staudacher, O.; Cyrull, S.; Dorr, J.; Mall, M. A.; Durek, P.; Kallinich, T.; Mashreghi, M-F; Lau, S.; von Stackelberg, A.; Romagnani, C.; Billadeau, D. D.; Akha, A. A. Sadighi; von Bernuth, H.
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs

肠神经系统来源的VIP抑制LGR5+干细胞向分泌谱系的分化，阻碍2型免疫程序。

Nature Immunology
IF27.6
2025-11-240
PRE
Manuel O. Jakob; Nele Sterczyk; Sotiria Boulekou; Patrycja M. Forster; Luisa Barleben; Nadra Alzain; Katja J. Jarick; Roksana M. Pirzgalska; Bruno Raposo; Karl Hansson; Elisabeth E. L. Nyström; Aurelia Gondrand; Miguel González-Acera; Pierre S. Leclère; Marlen S. Lapson; Sarah Poggenseier; Divija Deshpande; Laura Velleman; Tilman Breiderhoff; Max Felix Brunkhorst; Anton M. Schüle; Gabriela M. Guerra; Pawel Durek; Mir-Farzin Mashreghi; Anja A. Kühl; Coco Chu; Christoph Schneider; Carl Weidinger; Britta Siegmund; Thierry M. Nordmann; David Voehringer; Jay V. Patankar; Christoph Becker; George M. H. Birchenough; Henrique Veiga-Fernandes; Francesca Ronchi; Marina Kolesnichenko; Andreas Diefenbach; Christoph S. N. Klose
Two subsets of regulatory CD8+ T cells with differential transcriptome revealed by single cell analysis

通过单细胞分析揭示的具有差异转录组的两群调节性CD8+ T细胞。

iScience
IF4.1
2025-09-080
OAAI
Céline Sérazin; Lisa Dugast; Léa Flippe; Mathias Streitz; Désirée-Jacqueline Wendering; Stephan Schlickeiser; Frederik Heinrich; Pawel Durek; Gabriela Maria Guerra; Katrin Lehmann; Mir-Farzin Mashreghi; Harald Wajant; Hans Dieter Volk; Ignacio Anegon; Laurent David; Séverine Bézie; Carole Guillonneau
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis

Cineus, R.; Luo, Y.; Saliutina, M.; Manna, S.; Cancino, C.A.; Blazquez, L.V. IL-22-肿瘤坏死因子M轴促进肠道炎症和肿瘤发生。Nat. Immunol. 2025, 26, 837–853. [Google Scholar] [CrossRef]

Nature Immunology
IF27.6
2025-05-300
OA
Roodline Cineus; Yanjiang Luo; Mariia Saliutina; Subhakankha Manna; Camila A. Cancino; Luis Velasco Blázquez; Lifen Wang; Diana Bösel; Aya Abdelrahman; Joanna E. Klementowicz; Alexis Scherl; Saskia Hainbuch; Béatrice Bréart; Gino Kwon; Agata Konopka; Gabriela M. Guerra; Elena von Coburg; Lorenz Gerbeth; Juliette Roels; Frederik Heinrich; Nils Müller; Pawel Durek; Nikolaus Deigendesch; James Ziai; Jeffrey Hung; Thomas Conrad; Anja A. Kühl; Stefan Wirtz; Max Löhning; Mary Keir; Andreas Diefenbach; Mir-Farzin Mashreghi; Britta Siegmund; Michael Schumann; Chiara Romagnani; Nathaniel R. West; Ahmed N. Hegazy
Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells
NATURE COMMUNICATIONS
IF15.7
2024-12-040
OAAI
Troch, Karoline F.; Jakob, Manuel O.; Forster, Patrycja M.; Jarick, Katja J.; Schreiber, Jonathan; Preusser, Alexandra; Guerra, Gabriela M.; Durek, Pawel; Tizian, Caroline; Sterczyk, Nele; Helfrich, Sofia; Duerr, Claudia U.; Voehringer, David; Witkowski, Mario; Artis, David; Rollenske, Tim; Kruglov, Andrey A.; Mashreghi, Mir-Farzin; Klose, Christoph S. N.
Effector memory-type regulatory T cells display phenotypic and functional instability
SCIENCE ADVANCES
IF12.5
2024-09-060
OAAI
Wendering, Desiree Jacqueline; Amini, Leila; Schlickeiser, Stephan; Farrera-Sal, Marti; Schulenberg, Sarah; Peter, Lena; Mai, Marco; Vollmer, Tino; Du, Weijie; Stein, Maik; Hamm, Frederik; Malard, Alisier; Castro, Carla; Yang, Mingxing; Ranka, Ramon; Rueckert, Timo; Durek, Pawel; Heinrich, Frederik; Gasparoni, Gilles; Salhab, Abdulrahman; Walter, Joern; Wagner, Dimitrios Laurin; Mashreghi, Mir-Farzin; Landwehr-Kenzel, Sybille; Polansky, Julia K.; Reinke, Petra; Volk, Hans-Dieter; Schmueck-Henneresse, Michael
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow
NATURE COMMUNICATIONS
IF15.7
2024-05-171
OAAI
Ferreira-Gomes, Marta; Chen, Yidan; Durek, Pawel; Rincon-Arevalo, Hector; Heinrich, Frederik; Bauer, Laura; Szelinski, Franziska; Guerra, Gabriela Maria; Stefanski, Ana-Luisa; Niedobitek, Antonia; Wiedemann, Annika; Bondareva, Marina; Ritter, Jacob; Lehmann, Katrin; Hardt, Sebastian; Hipfl, Christian; Hein, Sascha; Hildt, Eberhard; Matz, Mareen; Mei, Henrik E.; Cheng, Qingyu; Dang, Van Duc; Witkowski, Mario; Lino, Andreia C.; Kruglov, Andrey; Melchers, Fritz; Perka, Carsten; Schrezenmeier, Eva V.; Hutloff, Andreas; Radbruch, Andreas; Doerner, Thomas; Mashreghi, Mir-Farzin
UNC93B1 variants underlie TLR7-dependent autoimmunity
SCIENCE IMMUNOLOGY
IF16.3
2024-02-2321
PRE
Wolf, Christine; Lim, Ee Lyn; Mokhtari, Mohammad; Kind, Barbara; Odainic, Alexandru; Lara-Villacanas, Eusebia; Koss, Sarah; Mages, Simon; Menzel, Katharina; Engel, Kerstin; Dueckers, Gregor; Bernbeck, Benedikt; Schneider, Dominik T.; Siepermann, Kathrin; Niehues, Tim; Goetzke, Carl Christoph; Durek, Pawel; Minden, Kirsten; Doerner, Thomas; Stittrich, Anna; Szelinski, Franziska; Guerra, Gabriela Maria; Massoud, Mona; Bieringer, Markus; Mann, Carina C. de Oliveira; Beltran, Eduardo; Kallinich, Tilmann; Mashreghi, Mir-Farzin; Schmidt, Susanne V.; Latz, Eicke; Klughammer, Johanna; Majer, Olivia; Lee-Kirsch, Min Ae
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses
NATURE IMMUNOLOGY
IF27.6
2024-01-032
OAAI
Brunner, Tobias M.; Serve, Sebastian; Marx, Anna-Friederike; Fadejeva, Jelizaveta; Saikali, Philippe; Dzamukova, Maria; Duran-Hernandez, Nayar; Kommer, Christoph; Heinrich, Frederik; Durek, Pawel; Heinz, Gitta A.; Hoefer, Thomas; Mashreghi, Mir-Farzin; Kuehn, Ralf; Pinschewer, Daniel D.; Loehning, Max
NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age- related osteoarthritis

NOS抑制逆转TLR2-induced软骨细胞功能障碍并减轻年龄相关性骨关节炎

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-07-108
OAAI
Shen, Ping; Serve, Sebastian; Wu, Peihua; Liu, Xiaohui; Dai, Yujie; Duran-Hernandez, Nayar; Nguyen, Dan Thi Mai; Fuchs, Michael; Maleitzke, Tazio; Reisener, Marie-Jacqueline; Dzamukova, Maria; Nussbaumer, Katrin; Brunner, Tobias M.; Li, Yonghai; Holecska, Vivien; Heinz, Gitta A.; Heinrich, Frederik; Durek, Pawel; Katsoula, Georgia; Gwinner, Clemens; Jung, Tobias; Zeggini, Eleftheria; Winkler, Tobias; Mashreghi, Mir-Farzin; Pumberger, Matthias; Perka, Carsten; Lohning, Max
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
NATURE COMMUNICATIONS
IF15.7
2023-02-1121
OAAI
Mothes, Ronja; Pascual-Reguant, Anna; Koehler, Ralf; Liebeskind, Juliane; Liebheit, Alina; Bauherr, Sandy; Philipsen, Lars; Dittmayer, Carsten; Laue, Michael; von Manitius, Regina; Elezkurtaj, Sefer; Durek, Pawel; Heinrich, Frederik; Heinz, Gitta A.; Guerra, Gabriela M.; Obermayer, Benedikt; Meinhardt, Jenny; Ihlow, Jana; Radke, Josefine; Heppner, Frank L.; Enghard, Philipp; Stockmann, Helena; Aschman, Tom; Schneider, Julia; Corman, Victor M.; Sander, Leif E.; Mashreghi, Mir-Farzin; Conrad, Thomas; Hocke, Andreas C.; Niesner, Raluca A.; Radbruch, Helena; Hauser, Anja E.
Questioning whether IgM Fc receptor (FcμR) is expressed by innate immune cells

质疑IgM Fc受体 (Fc μ r) 是否由先天免疫细胞表达

NATURE COMMUNICATIONS
IF15.7
2022-07-114
OAAI
Skopnik, Christopher M.; Riedel, Rene; Addo, Richard K.; Heinz, Gitta Anne; Heinrich, Frederik; Honjo, Kazuhito; Durek, Pawel; Enghard, Philipp; Mashreghi, Mir-Farzin; Radbruch, Andreas; Kubagawa, Hiromi
Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma
GUT MICROBES
IF11
2022-05-295
OAAI
Schmiester, Maren; Maier, Rene; Riedel, Rene; Durek, Pawel; Frentsch, Marco; Kolling, Stefan; Mashreghi, Mir-Farzin; Jenq, Robert; Zhang, Liangliang; Peterson, Christine B.; Bullinger, Lars; Chang, Hyun-Dong; Na, Il-Kang
B Cell Numbers Predict Humoral and Cellular Response Upon SARS-CoV-2 Vaccination Among Patients Treated With Rituximab

B细胞数量可预测利妥昔单抗治疗患者SARS-CoV-2疫苗接种后的体液和细胞反应

ARTHRITIS & RHEUMATOLOGY
IF10.9
2022-04-1748
OA
Stefanski, Ana-Luisa; Rincon-Arevalo, Hector; Schrezenmeier, Eva; Karberg, Kirsten; Szelinski, Franziska; Ritter, Jacob; Jahrsdoerfer, Bernd; Schrezenmeier, Hubert; Ludwig, Carolin; Sattler, Arne; Kotsch, Katja; Chen, Yidan; Claussnitzer, Anne; Haibel, Hildrun; Proft, Fabian; Guerra, Gabriela; Durek, Pawel; Heinrich, Frederik; Ferreira-Gomes, Marta; Burmester, Gerd R.; Radbruch, Andreas; Mashreghi, Mir-Farzin; Lino, Andreia C.; Doerner, Thomas
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability
MUCOSAL IMMUNOLOGY
IF7.6
2022-04-0114
OAAI
Ninnemann, Justus; Winsauer, Caroline; Bondareva, Marina; Kuehl, Anja A.; Lozza, Laura; Durek, Pawel; Lissner, Donata; Siegmund, Britta; Kaufmann, Stefan H. E.; Mashreghi, Mir-Farzin; Nedospasov, Sergei A.; Kruglov, Andrey A.
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development
SCIENCE IMMUNOLOGY
IF16.3
2021-11-266
PRE
Haftmann, Claudia; Zwicky, Pascale; Ingelfinger, Florian; Mair, Florian; Floess, Stefan; Riedel, Rene; Durek, Pawel; Spalinger, Marianne R.; Friebel, Ekaterina; Leung, Brian P.; Lutz, Mirjam; Puertas, Nicole; Amorim, Ana; Scharli, Stefanie; Becher, Benedict; Kisielow, Jan; Waisman, Ari; Mashreghi, Mir-Farzin; Huehn, Jochen; Becher, Burkhard
An in vitro platform supports generation of human innate lymphoid cells from CD34+ hematopoietic progenitors that recapitulate ex vivo identity
IMMUNITY
IF26.3
2021-10-0141
OAAI
Hernandez, Daniela Carolina; Juelke, Kerstin; Mueller, Nils Christian; Durek, Pawel; Ugursu, Bilge; Mashreghi, Mir-Farzin; Rueckert, Timo; Romagnani, Chiara
T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation
NATURE IMMUNOLOGY
IF27.6
2021-09-2325
OAAI
Stehle, Christina; Rueckert, Timo; Fiancette, Remi; Gajdasik, Dominika W.; Willis, Claire; Ulbricht, Carolin; Durek, Pawel; Mashreghi, Mir-Farzin; Finke, Daniela; Hauser, Anja Erika; Withers, David R.; Chang, Hyun-Dong; Zimmermann, Jakob; Romagnani, Chiara

研究方向

暂未获取到该数据
M
Mir‐Farzin Mashreghi
H 指数:37论文数:191被引数:6,700
F
Frederik Heinrich
H 指数:27论文数:83被引数:3,569
A
Andreas Radbruch
H 指数:113论文数:752被引数:4.5万
G
Gitta Anne Heinz
H 指数:25论文数:68被引数:3,475
H
Hyun‐Dong Chang
H 指数:43论文数:218被引数:9,273
G
Gabriela Maria Guerra
H 指数:13论文数:47被引数:1,058
C
Chiara Romagnani
H 指数:50论文数:128被引数:1.0万
A
Alf Hamann
H 指数:66论文数:211被引数:1.9万
T
Thomas Dörner
H 指数:97论文数:648被引数:4.2万
K
Katrin Lehmann
H 指数:20论文数:81被引数:1,556