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Z

ZhouChengji (Zhen Dong)

hebei agricultural university
H指数:25
被引数:2,886

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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

OGT通过抑制全基因组TET活性，阻止DNA去甲基化并抑制异染色质中转座子的表达。

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2025-03-281
OA
Sepulveda, Hugo; Li, Xiang; Arteaga-Vazquez, Leo J.; Lopez-Moyado, Isaac F.; Brunelli, Melina; Hernandez-Espinosa, Lot; Yue, Xiaojing; Angel, J. Carlos; Brown, Caitlin; Dong, Zhen; Jansz, Natasha; Puddu, Fabio; Modat, Aurelie; Scotcher, Jamie; Creed, Paidi; Kennedy, Patrick H.; Manriquez-Rodriguez, Cindy; Myers, Samuel A.; Crawford, Robert; Faulkner, Geoffrey J.
A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia

突变型ASXL1-BAP1-EHMT复合物在克隆性造血和慢性单核细胞性白血病中导致异染色质功能障碍。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-01-031
PRE
Dong, Zhen; Sepulveda, Hugo; Arteaga-Vazquez, Leo J.; Blouin, Chad; Fernandez, Jenna; Binder, Moritz; Chou, Wen-Chien; Tien, Hwei-Fang; Patnaik, Mrinal M.; Faulkner, Geoffrey J.; Myers, Samuel A.; Rao, Anjana
Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2021-10-0710
OAAI
Zhang, Guoxin; Dong, Zhen; Gimple, Ryan C.; Wolin, Arthur; Wu, Qiulian; Qiu, Zhixin; Wood, Lisa M.; Shen, Jia Z.; Jiang, Li; Zhao, Linjie; Lv, Deguan; Prager, Briana C.; Kim, Leo J. Y.; Wang, Xiuxing; Zhang, Lingdi; Anderson, Ryan L.; Moore, Jeffrey K.; Bao, Shideng; Keller, Thomas H.; Lin, Grace; Kang, Congbao; Hamerlik, Petra; Zhao, Rui; Ford, Heide L.; Rich, Jeremy N.
The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells

RNA m6A阅读器YTHDF2维持癌基因表达，并且是胶质母细胞瘤干细胞中的可靶向依赖性

CANCER DISCOVERY
IF33.3
2021-02-02270
OAAI
Dixit, Deobrat; Prager, Briana C.; Gimple, Ryan C.; Poh, Hui Xian; Wang, Yang; Wu, Qiulian; Qiu, Zhixin; Kidwell, Reilly L.; Kim, Leo J. Y.; Xie, Qi; Vitting-Seerup, Kristoffer; Bhargava, Shruti; Dong, Zhen; Jiang, Li; Zhu, Zhe; Hamerlik, Petra; Jaffrey, Samie R.; Zhao, Jing Crystal; Wang, Xiuxing; Rich, Jeremy N.
Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
CANCER DISCOVERY
IF33.3
2019-09-03126
OAAI
Gimple, Ryan C.; Kidwell, Reilly L.; Kim, Leo J. Y.; Sun, Tengqian; Gromovsky, Anthony D.; Wu, Qiulian; Wolf, Megan; Lv, Deguan; Bhargava, Shruti; Jiang, Li; Prager, Briana C.; Wang, Xiuxing; Ye, Qing; Zhu, Zhe; Zhang, Guoxin; Dong, Zhen; Zhao, Linjie; Lee, Derrick; Bi, Junfeng; Sloan, Andrew E.; Mischel, Paul S.; Brown, J. Mark; Cang, Hu; Huan, Tao; Mack, Stephen C.; Xie, Qi; Rich, Jeremy N.
Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
CELL STEM CELL
IF20.4
2018-04-01188
OAAI
Wang, Xiuxing; Prager, Briana C.; Wu, Qiulian; Kim, Leo J. Y.; Gimple, Ryan C.; Shi, Yu; Yang, Kailin; Morton, Andrew R.; Zhou, Wenchao; Zhu, Zhe; Obara, Elisabeth Anne Adanma; Miller, Tyler E.; Song, Anne; Lai, Sisi; Hubert, Christopher G.; Jin, Xun; Huang, Zhi; Fang, Xiaoguang; Dixit, Deobrat; Tao, Weiwei; Zhai, Kui; Chen, Cong; Dong, Zhen; Zhang, Guoxin; Dombrowski, Stephen M.; Hamerlik, Petra; Mack, Stephen C.; Bao, Shideng; Rich, Jeremy N.
MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells

MYC调节的甲羟戊酸代谢维持脑肿瘤起始细胞

CANCER RESEARCH
IF16.6
2017-09-14101
OAAI
Wang, Xiuxing; Huang, Zhi; Wu, Qiulian; Prager, Briana C.; Mack, Stephen C.; Yang, Kailin; Kim, Leo J. Y.; Gimple, Ryan C.; Shi, Yu; Lai, Sisi; Xie, Qi; Miller, Tyler E.; Hubert, Christopher G.; Song, Anne; Dong, Zhen; Zhou, Wenchao; Fang, Xiaoguang; Zhu, Zhe; Mahadev, Vaidehi; Bao, Shideng; Rich, Jeremy N.

研究方向

Tissue/organ morphogenesisDevelopmental disorders
Y
Ying Xu
H 指数:47论文数:391被引数:1.0万
R
Ryan C. Gimple
H 指数:35论文数:224被引数:6,500
L
Leo J.Y. Kim
H 指数:26论文数:113被引数:4,521
B
Briana C. Prager
H 指数:33论文数:168被引数:6,830
J
Jeremy N. Rich
H 指数:127论文数:1,484被引数:6.0万
Q
Qiulian Wu
H 指数:57论文数:134被引数:2.0万
汪秀星 封面图
汪秀星
H 指数:41论文数:245被引数:6,650
Z
Zhe Zhu
H 指数:36论文数:340被引数:6,052
G
Guangsen Shi
H 指数:19论文数:27被引数:1,155
L
Ling Yang
H 指数:16论文数:43被引数:842