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PERSONALIZED MULTIVALENT DNA VACCINATION SAFELY INDUCES BROAD NEOANTIGEN-SPECIFIC T CELL RESPONSES IN NEWLY DIAGNOSED MGMT UNMETHYLATED GLIOBLASTOMA IN A CLINICALLY RELEVANT TIME SCALE 个性化多价DNA疫苗接种安全地诱导新诊断的MGMT未甲基化胶质母细胞瘤中广泛的 neoantigen特异性T细胞反应，在临床上相关的时间尺度内。 Garfinkle, Elizabeth; Perales-Linares, Renzo; Gimple, Ryan; Yan, Jian; Navarro, Jaye; Paxton, Sophia; Livingstone, Alexandra; Roberts, Kaleigh; Cooch, Neil; Perales-Puchalt, Alfredo; Rochestie, Sarah; Peters, Joann; Campian, Jian; Junker, Beth; Chheda, Milan; Chicoine, Michael; Kim, Albert; Willie, Jon; Zipfel, Gregory; Dowling, Joshua; Gillanders, William; Miller, Katherine; Mardis, Elaine; Sardesai, Niranjan; Dunn, Gavin; Johanns, Tanner 分享 收藏
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Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression 对不同细胞状态胶质母细胞瘤干细胞的联合靶向可破坏恶性进展 Lu, Chenfei; Kang, Tao; Zhang, Junxia; Yang, Kailin; Liu, Yang; Song, Kefan; Lin, Qiankun; Dixit, Deobrat; Gimple, Ryan C.; Zhang, Qian; Shi, Zhumei; Fan, Xiao; Wu, Qiulian; Li, Daqi; Shan, Danyang; Gao, Jiancheng; Gu, Danling; You, Hao; Li, Yangqing; Yang, Junlei; Zhao, Linjie; Qiu, Zhixin; Yang, Hui; Zhao, Ningwei; Gao, Wei; Tao, Weiwei; Lu, Yingmei; Chen, Yun; Ji, Jing; Kang, Chunsheng; Man, Jianghong; Agnihotri, Sameer; Wang, Qianghu; Lin, Fan; Qian, Xu; Mack, Stephen C.; Hu, Zhibin; Li, Chaojun; Taylor, Michael D.; Liu, Ning; Zhang, Nu; Lu, Ming; You, Yongping; Wang, Xiuxing 分享 收藏
A peptide encoded by upstream open reading frame of MYC binds to tropomyosin receptor kinase B and promotes glioblastoma growth in mice 由MYC上游开放阅读框编码的肽与原肌球蛋白受体激酶B结合并促进小鼠胶质母细胞瘤的生长 Li, Fanying; Yang, Kailin; Gao, Xinya; Zhang, Maolei; Gu, Danling; Wu, Xujia; Lu, Chenfei; Wu, Qiulian; Dixit, Deobrat; Gimple, Ryan C.; You, Yongping; Mack, Stephen C.; Shi, Yu; Kang, Tiebang; Agnihotri, Sameer A.; Taylor, Michael D.; Rich, Jeremy N.; Zhang, Nu; Wang, Xiuxing 分享 收藏
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages Li, Daqi; Wang, Xiefeng; Chen, Kexin; Shan, Danyang; Cui, Gaoyuan; Yuan, Wei; Lin, Qiankun; Gimple, Ryan C.; Dixit, Deobrat; Lu, Chenfei; Gu, Danling; You, Hao; Gao, Jiancheng; Li, Yangqing; Kang, Tao; Yang, Junlei; Yu, Hang; Song, Kefan; Shi, Zhumei; Fan, Xiao; Wu, Qiulian; Gao, Wei; Zhu, Zhe; Man, Jianghong; Wang, Qianghu; Lin, Fan; Tao, Weiwei; Mack, Stephen C.; Chen, Yun; Zhang, Junxia; Li, Chaojun; Zhang, Nu; You, Yongping; Qian, Xu; Yang, Kailin; Rich, Jeremy N.; Zhang, Qian; Wang, Xiuxing 分享 收藏
Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism 淋巴管内皮样细胞通过细胞因子驱动的胆固醇代谢促进胶质母细胞瘤干细胞生长 Zhao, Linjie; Qiu, Zhixin; Yang, Zhengnan; Xu, Lian; Pearce, Thomas M.; Wu, Qiulian; Yang, Kailin; Li, Fulong; Saulnier, Olivier; Fei, Fan; Yu, Huaxu; Gimple, Ryan C.; Varadharajan, Venkateshwari; Liu, Juxiu; Hendrikse, Liam D.; Fong, Vernon; Wang, Wei; Zhang, Jiao; Lv, Deguan; Lee, Derrick; Lehrich, Brandon M.; Jin, Chunyu; Ouyang, Liang; Dixit, Deobrat; Wu, Haoxing; Wang, Xiang; Sloan, Andrew E.; Wang, Xiuxing; Huan, Tao; Mark Brown, J.; Goldman, Steven A.; Taylor, Michael D.; Zhou, Shengtao; Rich, Jeremy N. 分享 收藏
LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation Liu, Lihui; Liu, Ziyang; Liu, Qinghua; Wu, Wei; Lin, Peng; Liu, Xing; Zhang, Yuechuan; Wang, Dongpeng; Prager, Briana C.; Gimple, Ryan C.; Yu, Jichuan; Zhao, Weixi; Wu, Qiulian; Zhang, Wei; Wu, Erzhong; Chen, Xiaomin; Luo, Jianjun; Rich, Jeremy N.; Xie, Qi; Jiang, Tao; Chen, Runsheng 分享 收藏
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Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages CXCL8在维持胶质母细胞瘤干细胞和M2-Like肿瘤相关巨噬细胞间充质状态中的双重作用 Yuan, Wei; Zhang, Qian; Gu, Danling; Lu, Chenfei; Dixit, Deobrat; Gimple, Ryan C.; Gao, Yisu; Gao, Jiancheng; Li, Daqi; Shan, Danyang; Hu, Lang; Li, Lu; Li, Yangqing; Ci, Shusheng; You, Hao; Yan, Linping; Chen, Kexin; Zhao, Ningwei; Xu, Chuanhai; Lan, Jianyun; Liu, Dong; Zhang, Junxia; Shi, Zhumei; Wu, Qiulian; Yang, Kailin; Zhao, Linjie; Qiu, Zhixin; Lv, Deguang; Gao, Wei; Yang, Hui; Lin, Fan; Wang, Qianghu; Man, Jianghong; Li, Chaojun; Tao, Weiwei; Agnihotri, Sameer; Qian, Xu; Mack, Stephen C.; Zhang, Nu; You, Yongping; Rich, Jeremy N.; Sun, Guan; Wang, Xiuxing 分享 收藏
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting Gimple, Ryan C.; Zhang, Guoxin; Wang, Shuai; Huang, Tengfei; Lee, Jina; Taori, Suchet; Lv, Deguan; Dixit, Deobrat; Halbert, Matthew E.; Morton, Andrew R.; Kidwell, Reilly L.; Dong, Zhen; Prager, Briana C.; Kim, Leo J. Y.; Qiu, Zhixin; Zhao, Linjie; Xie, Qi; Wu, Qiulian; Agnihotri, Sameer; Rich, Jeremy N. 分享 收藏
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma Ye, Zengpanpan; Ai, Xiaolin; Yang, Kailin; Yang, Zhengnan; Fei, Fan; Liao, Xiaoling; Qiu, Zhixin; Gimple, Ryan C.; Yuan, Huairui; Huang, Hao; Gong, Yanqiu; Xiao, Chaoxin; Yue, Jing; Huang, Liang; Saulnier, Olivier; Wang, Wei; Zhang, Peidong; Dai, Lunzhi; Wang, Xin; Wang, Xiuxing; Ha Ahn, Young; You, Chao; Xu, Jianguo; Wan, Xiaoxiao; Taylor, Michael D.; Zhao, Linjie; Rich, Jeremy N.; Zhou, Shengtao 分享 收藏
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling Lee, Derrick; Gimple, Ryan C.; Wu, Xujia; Prager, Briana C.; Qiu, Zhixin; Wu, Qiulian; Daggubati, Vikas; Mariappan, Aruljothi; Gopalakrishnan, Jay; Sarkisian, Matthew R.; Raleigh, David R.; Rich, Jeremy N. 分享 收藏
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages Li, Daqi; Zhang, Qian; Li, Lu; Chen, Kexin; Yang, Junlei; Dixit, Deobrat; Gimple, Ryan C.; Ci, Shusheng; Lu, Chenfei; Hu, Lang; Gao, Jiancheng; Shan, Danyang; Li, Yangqing; Zhang, Junxia; Shi, Zhumei; Gu, Danling; Yuan, Wei; Wu, Qiulian; Yang, Kailin; Zhao, Linjie; Qiu, Zhixin; Lv, Deguang; Gao, Wei; Yang, Hui; Lin, Fan; Wang, Qianghu; Man, Jianghong; Li, Chaojun; Tao, Weiwei; Agnihotri, Sameer; Qian, Xu; Shi, Yu; You, Yongping; Zhang, Nu; Rich, Jeremy N.; Wang, Xiuxing 分享 收藏
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PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine Lv, Deguan; Gimple, Ryan C.; Zhong, Cuiqing; Wu, Qiulian; Yang, Kailin; Prager, Briana C.; Godugu, Bhaskar; Qiu, Zhixin; Zhao, Linjie; Zhang, Guoxin; Dixit, Deobrat; Lee, Derrick; Shen, Jia Z.; Li, Xiqing; Xie, Qi; Wang, Xiuxing; Agnihotri, Sameer; Rich, Jeremy N. 分享 收藏
Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy Lim, Yi Chieh; Jensen, Kamilla E.; Aguilar-Morante, Diana; Vardouli, Lina; Vitting-Seerup, Kristoffer; Gimple, Ryan C.; Wu, Qiulian; Pedersen, Henriette; Elbaek, Kirstine J.; Gromova, Irina; Ihnatko, Robert; Kristensen, Bjarne W.; Petersen, Jeanette K.; Skjoth-Rasmussen, Jane; Flavahan, William; Rich, Jeremy N.; Hamerlik, Petra 分享 收藏
ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance Jiang, Li; Hao, Yajing; Shao, Changwei; Wu, Qiulian; Prager, Briana C.; Gimple, Ryan C.; Sulli, Gabriele; Kim, Leo J. Y.; Zhang, Guoxin; Qiu, Zhixin; Zhu, Zhe; Fu, Xiang-Dong; Rich, Jeremy N. 分享 收藏
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