Yan Chen

Guizhou Medical University

H指数:23

被引数:1,410

个人简介

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POLG mediates CAF-stimulated TNBC cell metastasis by utilizing internal and exosome-derived external mtDNA to increase oxidative phosphorylation

POLG通过利用内源性和外泌体衍生的外源性线粒体DNA来增加氧化磷酸化，介导CAF刺激的TNBC细胞转移

Cell Death & Disease

IF9.6

2026-10-310

The liquid crystalline and optical properties of chiral symmetrical dimers with two azo groups and 1,2-propanediol chiral moiety

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2025-06-010

PRE

Impact of intensive health education on influenza vaccination and acute exacerbations in outpatients with chronic obstructive pulmonary disease: a real-world study

高强度健康教育对慢性阻塞性肺疾病门诊患者流感疫苗接种及急性加重的影响：一项真实世界研究

JOURNAL OF GLOBAL HEALTH

IF4.3

2025-03-070

Shikonin blocks CAF-induced TNBC metastasis by suppressing mitochondrial biogenesis through GSK-3β/NEDD4-1 mediated phosphorylation-dependent degradation of PGC-1α

紫草素通过GSK-3β/NEDD4-1介导的PGC-1α 磷酸化依赖性降解抑制线粒体生物合成来阻断CAF诱导的TNBC转移

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2024-06-271

OAAI

Gastrodin alleviates mitochondrial dysfunction by regulating SIRT3-mediated TFAM acetylation in vascular dementia

PHYTOMEDICINE

IF8.3

2024-06-012

PRE

Inhibition of MFN1 restores tamoxifen-induced apoptosis in resistant cells by disrupting aberrant mitochondrial fusion dynamics

CANCER LETTERS

IF10.1

2024-05-010

PRE

Essential oil from Fructus Alpinia zerumbet ameliorates atherosclerosis by activating PPARγ-LXRα-ABCA1/G1 signaling pathway

PHYTOMEDICINE

IF8.3

2024-01-013

PRE

Cyclovirobuxine D alleviates aldosterone-induced myocardial hypertrophy by protecting mitochondrial function depending on the mutual regulation of Nrf2-SIRT3

环维黄丁星D通过Nrf2-SIRT3的相互调节保护线粒体功能来减轻醛固酮诱导的心肌肥大

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-11-015

OAAI

GPER-mediated stabilization of HIF-1α contributes to upregulated aerobic glycolysis in tamoxifen-resistant cells

ONCOGENE

IF7.3

2022-11-189

PRE

Inhibition of Mitochondrial Biosynthesis using a Right-Side-Out Membrane-Camouflaged Micelle to Facilitate the Therapeutic Effects of Shikonin on Triple-Negative Breast Cancer

ADVANCED HEALTHCARE MATERIALS

IF9.6

2022-08-1213

PRE

Dual-Aptamer-Targeted Immunomagnetic Nanoparticles to Accurately Explore the Correlations between Circulating Tumor Cells and Gastric Cancer

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2022-02-0125

PRE

Deltamethrin interacts with Culex quinquefasciatus odorant-binding protein: a novel potential resistance mechanism

PARASITES & VECTORS

IF3.5

2022-01-0311

OAAI

Baicalein resensitizes tamoxifen-resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia-inducible factor-1α

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2021-11-0452

The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation

PHARMACOLOGICAL RESEARCH

IF10.5

2021-08-0127

OAAI

Metagenome Sequencing Reveals the Midgut Microbiota Makeup of Culex pipiens quinquefasciatus and Its Possible Relationship With Insecticide Resistance

宏基因组测序揭示了淡色库蚊的中肠菌群组成及其与杀虫剂抗性的可能关系

FRONTIERS IN MICROBIOLOGY

IF4.5

2021-02-2524

OAAI

Baicalein inhibits fibronectin-induced epithelial-mesenchymal transition by decreasing activation and upregulation of calpain-2 (vol 10, 341, 2019)

CELL DEATH & DISEASE

IF9.6

2020-07-131

OAAI

EOFAZ inhibits endothelial-to-mesenchymal transition through downregulation of KLF4

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

IF5.8

2020-04-0913

OAAI

Shikonin inhibits triple-negative breast cancer-cell metastasis by reversing the epithelial-to-mesenchymal transition via glycogen synthase kinase 3β-regulated suppression of β-catenin signaling

BIOCHEMICAL PHARMACOLOGY

IF5.6

2019-08-0149

PREAI

Identification and tissue expression profile of genes from three chemoreceptor families in an urban pest, Periplaneta americana

SCIENTIFIC REPORTS

IF3.9

2016-06-0924

OAAI

PAQR3 enhances Twist1 degradation to suppress epithelial-mesenchymal transition and metastasis of gastric cancer cells

CARCINOGENESIS

IF2.9

2016-02-1036

OAAI

Yan Chen

个人简介

教育背景

工作经历

荣誉奖项

研究方向