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赖德华 封面图

赖德华 (De‐Hua Lai)

Sun Yat-Sen University

26H指数
111论文数
3.6K被引数
收录论文 50
发表时间
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Identification of New Anti-Trypanosoma brucei Leads: An Integrated CRK12-Guided Virtual Screen With Experimental Validation鉴定新型抗锥虫属布鲁氏锥虫先导化合物：一种整合CRK12指导的虚拟筛选与实验验证的方法
errChemical Biology & Drug Design
IF3.3
err2026-09-10
err0
errOAAI
errQin Li; Chenggong Fu; Jiayi Luo; Qianqian Zhang; Lingling Wang; Xiaomeng Liu; Jiayue Qiu; Xiaoqing Gong; Henry H. Y. Tong; Xiaojun Yao; Dehua Lai; Huanxiang Liu
err分享
err收藏
Cell cycle of Trypanosoma epinepheli bloodstream forms in vivo and in vitro真鳗锥虫（Trypanosoma epinepheli）血鞭毛体在体内和体外的细胞周期
errCurrent Zoology
IF2
err2025-12-01
err0
errOAAI
errLiang, Yu-Bei; Chen, Ke; Xie, Zhi-Qiang; Zhang, Peng; Hide, Geoff; Hong, Xiaokun; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
Ultrastructural and morphological characterization of Trypanosoma bubalisi reveals an active endocytic system长颈鹿锥虫（Trypanosoma bubalisi）的超微结构和形态学表征揭示了其活跃的内吞系统
errACTA TROPICA
IF2.5
err2025-12-01
err0
PREAI
errWang, Ju-Feng; Bi, Ying-Xin; Yang, Jiong; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
Kinetoplast DNA structure, RNA editing patterns and small respiratory Complex I in Trypanosoma musculi锥虫Trypanosoma musculi的动粒体DNA结构、RNA编辑模式和小型呼吸链复合物I
errCommunications Biology
IF5.1
err2025-11-07
err0
errOAAI
errJu-Feng Wang; Ying-Xin Bi; Michael Hammond; Julius Lukeš; De-Hua Lai; Zhao-Rong Lun
err分享
err收藏
Thermo-related degeneration of stumpy forms of Trypanosoma brucei, the pathogen of African sleeping sickness与热相关的布氏锥虫(非洲昏睡病的病原体)的粗短形态的退化
errADVANCED BIOTECHNOLOGY
IF0
err2025-09-23
err0
errOAAI
errLuo, Jia-Yi; Wang, Ju-Feng; Yang, Jiong; Zhang, Peng; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
Effects of artesunate-loaded nanoparticles on Plasmodium berghei treatment in a mouse modelartesunate-loaded nanoparticles 对伯氏疟原虫在小鼠模型中治疗效果的影响
errACTA TROPICA
IF2.5
err2025-09-01
err0
PREAI
errWen, Haoshen; Li, Yawei; Luo, Jiayi; Zhu, Wenhe; Hide, Geoff; Feng, Xianmin; Lun, Zhao-Rong; Lai, De-Hua
err分享
err收藏
Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection
errBMC INFECTIOUS DISEASES
IF3
err2024-10-17
err0
errOAAI
errXie, Yiting; Zhang, Congxi; Tang, Petrus; Hide, Geoff; Lai, Dehua; Lun, Zhao-Rong
err分享
err收藏
First outbreak of trypanosomiasis in farmed blood parrot cichlids ( Vieja melanura 9 x Amphilophus citrinellus ♂ ) from southern China
errAQUACULTURE
IF3.9
err2024-07-01
err1
PREAI
errZhou, Jun-Yu; Xu, Liwen; Bi, Ying-Xin; Zhang, Jinyong; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
Morphological and molecular characteristics of a Trypanosoma sp. from triatomines (Triatoma rubrofasciata) in China
errPARASITES & VECTORS
IF3.5
err2024-05-10
err0
errOAAI
errShi, Yunliang; Lai, Dehua; Liu, Dengyu; Du, Liyan; Li, Yuanyuan; Fu, Xiaoyin; Deng, Peichao; Tang, Lili; He, Shanshan; Liu, Xiaoquan; Li, Yanwen; Liu, Qin
err分享
err收藏
Apicomplexa micropore: history, function, and formation
errTrends in Parasitology
IF6.6
err2024-05-01
err0
PREAI
errYang, Jiong; Long, Shaojun; Hide, Geoff; Lun, Zhao-Rong; Lai, De-Hua
err分享
err收藏
The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival
errELIFE
IF0
err2024-03-19
err4
errOAAI
errDong, Hui; Yang, Jiong; He, Kai; Zheng, Wen-Bin; Lai, De-Hua; Liu, Jing; Ding, Hui-Yong; Wu, Rui-Bin; Brown, Kevin M.; Hide, Geoff; Lun, Zhao-Rong; Zhu, Xing-Quan; Long, Shaojun
err分享
err收藏
Towards disentangling the classification of freshwater fish trypanosomes
errMARINE LIFE SCIENCE & TECHNOLOGY
IF5.3
err2023-10-13
err3
errOAAI
errZhang, Peng; Liu, Jie; Yin, Xiao-Ming; Zhou, Jun-Yu; Lukes, Julius; Lun, Zhao-Rong; Lai, De-Hua
err分享
err收藏
Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting
errMBIO
IF4.7
err2023-08-07
err11
errOAAI
errWang, Qiang-Qiang; Sun, Ming; Tang, Tao; Lai, De-Hua; Liu, Jing; Maity, Sanjay; He, Kai; Wu, Xi-Ting; Yang, Jiong; Li, Yue-Bao; Tang, Xiao-Yan; Ding, Hui-Yong; Hide, Geoff; Distefano, Mark; Lun, Zhao-Rong; Zhu, Xing-Quan; Long, Shaojun
err分享
err收藏
Cryo-Electron Tomography of Toxoplasma gondii Indicates That the Conoid Fiber May Be Derived from Microtubules
errADVANCED SCIENCE
IF14.1
err2023-02-25
err6
errOAAI
errLi, Zhixun; Du, Wenjing; Yang, Jiong; Lai, De-Hua; Lun, Zhao-Rong; Guo, Qiang
err分享
err收藏
The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments
errNATURE COMMUNICATIONS
IF15.7
err2023-02-22
err24
errOAAI
errWan, Wenyan; Dong, Hui; Lai, De-Hua; Yang, Jiong; He, Kai; Tang, Xiaoyan; Liu, Qun; Hide, Geoff; Zhu, Xing-Quan; Sibley, L. David; Lun, Zhao-Rong; Long, Shaojun
err分享
err收藏
Inflammasome Activation Dampens Type I IFN Signaling to Strengthen Anti-Toxoplasma Immunity炎症小体激活抑制I型IFN信号增强抗弓形虫免疫
errMBIO
IF4.7
err2022-12-20
err11
errOAAI
errHu, Zhiqiang; Wu, Dan; Lu, Jiansen; Zhang, Yufen; Yu, Shao-Meng; Xie, Yingchao; Li, Hongyu; Yang, Jianwu; Lai, De-Hua; Zeng, Ke; Jiang, Huaji; Lun, Zhao-Rong; Yu, Xiao
err分享
err收藏
iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2022-05-18
err11
errOAAI
errShen, Jia; Yu, Si-fei O.; Peng, Mei; Lai, De-Hua O.; Hide, Geoff; Wu, Zhong-Dao O.; Lun, Zhao-Rong
err分享
err收藏
A new species of mammalian trypanosome, Trypanosoma (Megatrypanum) bubalisi sp. nov., found in the freshwater leech Hirudinaria manillensis
errINTERNATIONAL JOURNAL FOR PARASITOLOGY
IF3.2
err2022-03-01
err5
PREAI
errSu, Bi-Xiu; Wang, Ju-Feng; Yang, Ting-Bao; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
The Occurrence of Malignancy in Trypanosoma brucei brucei by Rapid Passage in Mice
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2022-01-11
err2
errOAAI
errCai, Xiao-Li; Li, Su-Jin; Zhang, Peng; Li, Ziyin; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏
Species identification and phylogenetic analysis of Leishmania isolated from patients, vectors and hares in the Xinjiang Autonomous Region, The People's Republic of China
errPLOS NEGLECTED TROPICAL DISEASES
IF3.4
err2021-12-17
err4
errOAAI
errChen, Yun-Fu; Liao, Li-Fu; Wu, Na; Gao, Jiang-Mei; Zhang, Peng; Wen, Yan-Zi; Hide, Geoff; Lai, De-Hua; Lun, Zhao-Rong
err分享
err收藏

研究方向

锥虫的退化CRK12抑制剂人非洲锥虫病弓形虫超微结构Apicomplexa micropore功能与形成弓形虫微孔内吞作用营养劫持哺乳动物锥虫新种发现利什曼原虫物种鉴定与系统发育分析Toxoplasma gondii infectioninducible nitric oxide synthase基体连接蛋白在锥虫基体遗传中的功能锥虫线粒体微小环组织原生动物学研究寄生虫发育一氧化氮免疫力人间充质基质细胞刚地弓形虫输入性皮肤利什曼病病原体鉴定基因组与系统发育分析动基体缺失传染病学锥虫属和苏拉病叶绿体基因组分裂光系统蛋白线性映射拓扑结构复杂性生长锥虫线粒体锥虫进化与传播Trypanosoma brucei evansi血清敏感性锥虫血清抵抗相关基因进化华支睾吸虫分子遗传分析人嗜酸性脑膜炎抗寄生原虫药物伊氏锥虫马媾疫锥虫布氏锥虫华支睾吸虫病
合作学者
合作期刊
L
L. David Sibley
H 指数: 112 · 论文数: 361
P
Patrick J. Keeling
H 指数: 98 · 论文数: 572
R
Robin B. Gasser
H 指数: 92 · 论文数: 1.0K
K
Keith Gull
H 指数: 88 · 论文数: 906
M
Masahiro Yamamoto
H 指数: 87 · 论文数: 428
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