Shimeng Guo

Chongqing Medical University

H指数:20

被引数:1,556

个人简介

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教育背景

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荣誉奖项

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Research progress of gut microbiota and its metabolites in polycystic ovary syndrome

多囊卵巢综合征中肠道微生物群及其代谢物的研究进展

Frontiers in Endocrinology

IF4.6

2025-12-170

OAAI

Exposure to zinc oxide nanoparticles inhibits preimplantation embryonic development by disrupting zygotic genome activation

氧化锌纳米颗粒暴露通过破坏合子基因组激活抑制植入前胚胎发育

Cell Biology and Toxicology

IF5.9

2025-12-100

OAAI

Autophagy regulates the maternal-to-zygotic transition through MAP1LC3B-mediated maternal mRNA decay

自噬通过MAP1LC3B介导的母体mRNA降解调控母源-合子转换

AUTOPHAGY

IF14.3

2025-11-010

PRE

Intratumoral Microenvironment Remodeling by lncRNA ROLLCSC Enhances Lung Adenocarcinoma Progression.

lncRNA ROLLCSC介导的肿瘤微环境重塑增强了肺腺癌进展。

Genes & Diseases

IF9.4

2025-08-050

OAAI

Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signaling

GPR4中pH感应和激活的分子机制揭示了质子介导的GPCR信号

Cell Discovery

IF12.5

2025-06-250

OAAI

Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor

生长激素分泌素受体对两种获批药物Macimorelin和Anamorelin的分子识别

Acta Pharmacologica Sinica

IF8.4

2025-06-200

PRE

KLF12 transcriptional activation by a novel LncRNA A930015D03Rik enhances melanoma metastasis

LncRNA A930015D03Rik介导的KLF12转录激活增强黑色素瘤转移

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-05-010

PRE

Discovery of potent free fatty acid receptor 1 full agonists with a novel scaffold bearing conjugated double bond linker

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2025-03-010

PRE

V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor

CELL AND BIOSCIENCE

IF6.2

2024-08-311

OAAI

Structural and functional evidence that GPR30 is not a direct estrogen receptor (Vol 34, Pg 530, 2024)

CELL RESEARCH

IF25.9

2024-07-290

Structural basis of tethered agonism and G protein coupling of protease-activated receptors

蛋白酶激活受体的束缚激动和g蛋白偶联的结构基础

CELL RESEARCH

IF25.9

2024-07-120

OAAI

Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair

拓扑异构酶抑制剂和PIM1激酶抑制剂通过CRISPR-Cas9和同源定向修复介导提高基因编辑效率

MOLECULES

IF4.6

2024-06-180

OAAI

Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor

CELL DISCOVERY

IF12.5

2024-06-040

OAAI

A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2024-06-012

PRE

Structural and functional evidence that GPR30 is not a direct estrogen receptor

CELL RESEARCH

IF25.9

2024-05-143

PRE

The landscape of transcriptional profiles in human oocytes with different chromatin configurations

JOURNAL OF OVARIAN RESEARCH

IF4.2

2024-05-102

OAAI

Deficiency of nucleosome-destabilizing factor GLYR1 dampens spermatogenesis in mice

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2024-05-010

PRE

Cryo-EM structures of adenosine receptor A3AR bound to selective agonists

腺苷受体A3AR与选择性激动剂结合的cryo-em结构

NATURE COMMUNICATIONS

IF15.7

2024-04-1611

OAAI

Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-01-011

PRE

Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-12-012

PRE

Shimeng Guo

个人简介

教育背景

工作经历

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