未登录.png)
分享.png)
收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Rational design strategy for thermostability enhancement of protein-glutaminase and investigation of the underlying mechanisms蛋白质谷氨酰胺酶热稳定性增强的理性设计策略及其作用机制的探究
Wu, Jiajing; Wang, Lina; Sun, Yixin; Lv, Shuai; Wu, Jing; Zheng, Lihui; Wang, Cong; Su, Wei; Zhang, Zheng; Chang, Zhongyi; Jin, Mingfei; Gao, Hongliang; Zhang, Qiansen; Huang, Jing 分享 收藏 分享 收藏 Small molecule inhibits KCNQ channels with a non-blocking mechanism小分子通过非阻断机制抑制KCNQ通道Li, Junnan; Yang, Zhenni; Zhang, Shaoying; Ye, Yangliang; He, Jiangnan; Zhang, Yan; Han, Huayun; Kong, Wan; Liu, Jiangru; Min, Yu; Shen, Juwen; Mei, Lianghe; Chen, Zongsheng; Hou, Panpan; Guo, Jiangtao; Zhang, Qiansen 分享 收藏 分享 收藏 Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment发现用于胰腺癌治疗的高选择性和有效的STAT3抑制剂Chen, Huang; Bian, Aiwu; Zhou, Wenbo; Miao, Ying; Ye, Jiangnan; Li, Jiahui; He, Peng; Zhang, Qiansen; Sun, Yue; Sun, Zhenliang; Ti, Chaowen; Chen, Yihua; Yi, Zhengfang; Liu, Mingyao 分享 收藏 A small-molecule activation mechanism that directly opens the KCNQ2 channelZhang, Shaoying; Ma, Demin; Wang, Kun; Li, Ya; Yang, Zhenni; Li, Xiaoxiao; Li, Junnan; He, Jiangnan; Mei, Lianghe; Ye, Yangliang; Chen, Zongsheng; Shen, Juwen; Hou, Panpan; Guo, Jiangtao; Zhang, Qiansen; Yang, Huaiyu 分享 收藏 Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channelsLiu, Heng; Polovitskaya, Maya M.; Yang, Linlin; Li, Meiling; Li, Hongyu; Han, Zhen; Wu, Jianguo; Zhang, Qiansen; Jentsch, Thomas J.; Liao, Jun 分享 收藏 Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer ImmunotherapyCheng, Zhiyuan; Wang, Yijie; Zhang, Yao; Zhang, Chan; Wang, Mengru; Wang, Wei; He, Jiacheng; Wang, Yang; Zhang, Hankun; Zhang, Qiansen; Ding, Chunyong; Wu, Deyan; Yang, Linlin; Liu, Mingyao; Lu, Weiqiang 分享 收藏 Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic CancerChen, Huang; Zhou, Wenbo; Bian, Aiwu; Zhang, Qiansen; Miao, Ying; Yin, Xuan; Ye, Jiangnan; Xu, Shifen; Ti, Chaowen; Sun, Zhenliang; Zheng, Jianghua; Chen, Yihua; Liu, Mingyao; Yi, Zhengfang 分享 收藏 General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel GatesLiu, Shijie; Guo, Peipei; Wang, Kun; Zhang, Shaoying; Li, Ya; Shen, Juwen; Mei, Lianghe; Ye, Yangliang; Zhang, Qiansen; Yang, Huaiyu 分享 收藏 Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer ImmunotherapyWang, Wei; He, Jiacheng; Yang, Junjie; Zhang, Chan; Cheng, Zhiyuan; Zhang, Yao; Zhang, Qiansen; Wang, Peili; Tang, Shuowen; Wang, Xin; Liu, Mingyao; Lu, Weiqiang; Zhang, Han-Kun 分享 收藏 SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumorsWang, Xiaomin; Chen, Ziqi; Xu, Jun; Tang, Shuai; An, Nan; Jiang, Lei; Zhang, Yixiang; Zhang, Shaoying; Zhang, Qingli; Shen, Yanyan; Chen, Shijie; Lan, Xiaojing; Wang, Ting; Zhai, Linhui; Cao, Siyuwei; Guo, Siqi; Liu, Yingluo; Bi, Aiwei; Chen, Yuehong; Gai, Xiameng; Duan, Yichen; Zheng, Ying; Fu, Yixian; Li, Yize; Yuan, Liang; Tong, Linjiang; Mo, Kun; Wang, Mingcheng; Lin, Shu-Hai; Tan, Minjia; Luo, Cheng; Chen, Yi; Liu, Jia; Zhang, Qiansen; Li, Leping; Huang, Min 分享 收藏 An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo一种可口服的小分子BCL6抑制剂可有效抑制体内和体外弥漫性大b细胞淋巴瘤细胞的生长Xing, Yajing; Guo, Weikai; Wu, Min; Xie, Jiuqing; Huang, Dongxia; Hu, Pan; Zhou, Miaoran; Zhang, Lin; Zhang, Qiansen; Wang, Peili; Wang, Xin; Wang, Guixue; Wu, Huangan; Zhou, Cili; Chen, Yihua; Liu, Mingyao; Yi, Zhengfang; Sun, Zhenliang 分享 收藏 Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects抑制外周感觉神经元Hv1通道减轻慢性炎性痛和阿片类药物副作用Zhang, Qiansen; Ren, Yimin; Mo, Yiqing; Guo, Peipei; Liao, Ping; Luo, Yuncheng; Mu, Jie; Chen, Zhuo; Zhang, Yang; Li, Ya; Yang, Linghui; Liao, Daqing; Fu, Jie; Shen, Juwen; Huang, Wei; Xu, Xuewen; Guo, Yanyan; Mei, Lianghe; Zuo, Yunxia; Liu, Jin; Yang, Huaiyu; Jiang, Ruotian 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
